Project name: 3fzu

Chain sequence(s)	A: DIQMTQSPSSLSASVGDRVTITCRASQDIRYYLNWYQQKPGKAPKLLIYVASSLQSGVPSRFSGSGSGTEFTLTVSSLQPEDFATYYCLQVYSTPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEEVQLVESGGGLAKPGGSLRLSCAASGFRFTFNNYYMDWVRQAPGQGLEWVSRISSSGDPTWYADSVKGRFTISRENAKNTLFLQMNSLRAEDTAVYYCASLTTGSDSWGQGVLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3915
• Maximal score value: 0.8444
• Average score: -0.743
• Total score value: -319.498

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-1.8320
2	I	A	-1.0873
3	Q	A	-1.3500
4	M	A	0.0000
5	T	A	-1.1500
6	Q	A	0.0000
7	S	A	-0.7327
8	P	A	-0.6413
9	S	A	-0.8548
10	S	A	-0.7151
11	L	A	-0.3724
12	S	A	-0.6382
13	A	A	0.0000
14	S	A	-0.6759
15	V	A	0.2240
16	G	A	-0.4124
17	D	A	-1.4028
18	R	A	-2.1342
19	V	A	-0.9798
20	T	A	-0.4125
21	I	A	0.0000
22	T	A	-0.6514
23	C	A	0.0000
24	R	A	-2.2673
25	A	A	-1.9219
26	S	A	-1.8688
27	Q	A	-2.4095
28	D	A	-2.7103
29	I	A	0.0000
30	R	A	-1.6803
31	Y	A	-0.2604
32	Y	A	0.4199
33	L	A	0.0000
34	N	A	0.0000
35	W	A	0.0000
36	Y	A	0.0000
37	Q	A	-1.1137
38	Q	A	0.0000
39	K	A	-1.9234
40	P	A	-1.5077
41	G	A	-1.7958
42	K	A	-2.5674
43	A	A	-1.8274
44	P	A	0.0000
45	K	A	-2.1133
46	L	A	0.0000
47	L	A	0.0000
48	I	A	0.0000
49	Y	A	0.3289
50	V	A	0.0000
51	A	A	0.0000
52	S	A	-0.0927
53	S	A	0.0468
54	L	A	0.2808
55	Q	A	-0.3681
56	S	A	-0.2377
57	G	A	-0.1984
58	V	A	-0.0084
59	P	A	-0.3475
60	S	A	-0.4212
61	R	A	-0.8587
62	F	A	0.0000
63	S	A	-0.3113
64	G	A	-0.2633
65	S	A	-0.5464
66	G	A	-1.0903
67	S	A	-1.3986
68	G	A	-2.1450
69	T	A	-2.1944
70	E	A	-2.1047
71	F	A	0.0000
72	T	A	-0.6424
73	L	A	0.0000
74	T	A	-0.5525
75	V	A	0.0000
76	S	A	-1.3610
77	S	A	-1.0285
78	L	A	0.0000
79	Q	A	-0.8558
80	P	A	-1.6634
81	E	A	-1.9948
82	D	A	0.0000
83	F	A	-1.1071
84	A	A	0.0000
85	T	A	-0.7533
86	Y	A	0.0000
87	Y	A	0.0000
88	C	A	0.0000
89	L	A	0.0000
90	Q	A	0.0000
91	V	A	0.8444
92	Y	A	0.6255
93	S	A	0.4137
94	T	A	0.1567
95	P	A	-0.2967
96	R	A	0.0000
97	T	A	-0.3987
98	F	A	0.0000
99	G	A	0.0000
100	Q	A	-1.6206
101	G	A	-1.2405
102	T	A	-0.9974
103	K	A	-1.2653
104	V	A	0.0000
105	E	A	-1.1838
106	I	A	0.0000
107	K	A	-1.0856
108	R	A	-0.7293
109	T	A	0.0928
110	V	A	0.7683
111	A	A	0.0752
112	A	A	-0.1639
113	P	A	-0.4201
114	S	A	-0.3730
115	V	A	0.0982
116	F	A	0.3695
117	I	A	0.2720
118	F	A	0.0000
119	P	A	-0.5122
120	P	A	-0.6480
121	S	A	-1.4369
122	D	A	-2.7058
123	E	A	-2.4777
124	Q	A	0.0000
125	L	A	-1.7891
126	K	A	-2.6633
127	S	A	-1.6660
128	G	A	-1.3031
129	T	A	-1.0291
130	A	A	-0.9780
131	S	A	0.0000
132	V	A	0.0000
133	V	A	0.0000
134	C	A	0.0000
135	L	A	0.0000
136	L	A	0.0000
137	N	A	-0.7916
138	N	A	-1.7330
139	F	A	0.0000
140	Y	A	-1.0594
141	P	A	-1.4755
142	R	A	-2.3345
143	E	A	-2.9791
144	A	A	-2.1239
145	K	A	-2.5261
146	V	A	-1.3017
147	Q	A	-0.9539
148	W	A	0.0000
149	K	A	-0.5530
150	V	A	0.0000
151	D	A	-1.7996
152	N	A	-1.4782
153	A	A	-0.1969
154	L	A	0.6585
155	Q	A	-0.2733
156	S	A	-0.5264
157	G	A	-0.9800
158	N	A	-1.1342
159	S	A	-1.3253
160	Q	A	-1.4855
161	E	A	-1.5105
162	S	A	-0.4065
163	V	A	-0.0855
164	T	A	-0.7007
165	E	A	-1.4985
166	Q	A	0.0000
167	D	A	-2.3796
168	S	A	-2.3455
169	K	A	-2.7844
170	D	A	-2.3065
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-0.7516
175	L	A	-0.2147
176	S	A	0.0000
177	S	A	-0.7540
178	T	A	-0.6894
179	L	A	0.0000
180	T	A	-0.4824
181	L	A	-0.5681
182	S	A	0.0000
183	K	A	-1.8670
184	A	A	-1.6083
185	D	A	-2.1920
186	Y	A	0.0000
187	E	A	-3.3860
188	K	A	-3.3915
189	H	A	-2.9748
190	K	A	-3.0267
191	V	A	-1.7731
192	Y	A	0.0000
193	A	A	-0.7465
194	C	A	0.0000
195	E	A	-0.7015
196	V	A	0.0000
197	T	A	-1.1916
198	H	A	0.0000
199	Q	A	-1.6719
200	G	A	-0.4276
201	L	A	-0.0889
202	S	A	-0.3966
203	S	A	-0.3944
204	P	A	-0.4699
205	V	A	0.0212
206	T	A	-0.4484
207	K	A	-0.6260
208	S	A	-0.6226
209	F	A	-0.8627
210	N	A	-1.9919
211	R	A	-2.3384
212	G	A	-1.6294
1	E	A	-2.0239
2	V	A	-1.2620
3	Q	A	-0.9738
4	L	A	0.0000
5	V	A	0.8239
6	E	A	0.0319
7	S	A	-0.5192
8	G	A	-0.9400
9	G	A	-0.8057
10	G	A	-0.5093
11	L	A	-0.2301
12	A	A	-1.0119
13	K	A	-2.1302
14	P	A	-1.9818
15	G	A	-1.6295
16	G	A	-1.5010
17	S	A	-1.5185
18	L	A	-1.3194
19	R	A	-1.9656
20	L	A	0.0000
21	S	A	-0.4892
22	C	A	0.0000
23	A	A	-0.2611
24	A	A	-0.1112
25	S	A	-0.6285
26	G	A	-1.1080
27	F	A	-0.5621
28	R	A	-1.0003
29	F	A	0.6247
30	T	A	-0.2154
31	F	A	0.0000
32	N	A	-1.7662
33	N	A	-0.8700
34	Y	A	0.0000
35	Y	A	0.5219
36	M	A	0.0000
37	D	A	0.0000
38	W	A	0.0000
39	V	A	0.0000
40	R	A	0.0000
41	Q	A	-0.7576
42	A	A	-1.0930
43	P	A	-1.0855
44	G	A	-1.2442
45	Q	A	-1.9066
46	G	A	-1.4884
47	L	A	0.0000
48	E	A	-1.1532
49	W	A	0.0000
50	V	A	0.0000
51	S	A	0.0000
52	R	A	-0.2277
53	I	A	0.0000
54	S	A	0.0000
55	S	A	-0.6987
56	S	A	-1.1094
57	G	A	-1.4598
58	D	A	-2.1154
59	P	A	-1.4158
60	T	A	-0.6233
61	W	A	-0.5155
62	Y	A	-0.8638
63	A	A	-1.4708
64	D	A	-2.4502
65	S	A	-1.8094
66	V	A	0.0000
67	K	A	-2.5202
68	G	A	-1.7698
69	R	A	-1.5713
70	F	A	0.0000
71	T	A	-0.8230
72	I	A	0.0000
73	S	A	-0.7760
74	R	A	-1.5896
75	E	A	-2.3916
76	N	A	-2.6781
77	A	A	-2.0044
78	K	A	-3.0699
79	N	A	-2.9679
80	T	A	-1.8268
81	L	A	0.0000
82	F	A	-0.4862
83	L	A	0.0000
84	Q	A	-1.2177
85	M	A	0.0000
86	N	A	-1.6747
87	S	A	-1.4078
88	L	A	0.0000
89	R	A	-2.2219
90	A	A	-1.6860
91	E	A	-2.2004
92	D	A	0.0000
93	T	A	-0.6688
94	A	A	0.0000
95	V	A	0.2927
96	Y	A	0.0000
97	Y	A	0.0000
98	C	A	0.0000
99	A	A	0.0000
100	S	A	0.0000
101	L	A	0.0000
102	T	A	0.0135
103	T	A	-0.3060
104	G	A	-0.6838
105	S	A	-0.4887
106	D	A	-0.9660
107	S	A	0.0000
108	W	A	-0.5959
109	G	A	-0.7215
110	Q	A	-1.4247
111	G	A	-0.5666
112	V	A	-0.0242
113	L	A	0.2918
114	V	A	0.0000
115	T	A	0.0000
116	V	A	0.0000
117	S	A	-0.9206
118	S	A	-0.8848
119	A	A	-0.5222
120	S	A	-0.5511
121	T	A	-0.4656
122	K	A	-0.9724
123	G	A	-1.3221
124	P	A	-0.5637
125	S	A	-0.3645
126	V	A	0.0000
127	F	A	-0.7437
128	P	A	-1.1579
129	L	A	0.0000
130	A	A	-0.8304
131	P	A	0.0000
132	S	A	-1.2723
133	S	A	-1.3491
134	K	A	-1.8966
135	S	A	-1.3238
136	T	A	-0.9053
137	S	A	-0.8561
138	G	A	-1.0026
139	G	A	-0.8899
140	T	A	-0.5955
141	A	A	-0.6055
142	A	A	-0.1442
143	L	A	0.0000
144	G	A	0.0000
145	C	A	0.0000
146	L	A	0.0000
147	V	A	0.0000
148	K	A	0.0000
149	D	A	-0.4093
150	Y	A	0.0000
151	F	A	0.0000
152	P	A	0.0000
153	E	A	-0.6548
154	P	A	-0.6634
155	V	A	-0.6504
156	T	A	-0.5491
157	V	A	-0.1542
158	S	A	-0.4562
159	W	A	0.0000
160	N	A	-0.8326
161	S	A	-0.6594
162	G	A	-0.5593
163	A	A	-0.2748
164	L	A	-0.0344
165	T	A	-0.2843
166	S	A	-0.3014
167	G	A	-0.3835
168	V	A	-0.3349
169	H	A	-0.9253
170	T	A	-0.4214
171	F	A	0.0000
172	P	A	-0.4628
173	A	A	0.1092
174	V	A	0.2616
175	L	A	0.6400
176	Q	A	-0.0764
177	S	A	-0.4388
178	S	A	-0.3284
179	G	A	-0.1640
180	L	A	0.0634
181	Y	A	0.3443
182	S	A	0.0000
183	L	A	0.0000
184	S	A	0.0000
185	S	A	0.0000
186	V	A	0.0000
187	V	A	0.0000
188	T	A	-0.2709
189	V	A	0.0000
190	P	A	-0.5705
191	S	A	-0.7910
192	S	A	-0.4743
193	S	A	-0.3097
194	L	A	-0.4754
195	G	A	-0.7433
196	T	A	-0.7247
197	Q	A	-0.8872
198	T	A	-0.9689
199	Y	A	0.0000
200	I	A	-1.3247
201	C	A	0.0000
202	N	A	-1.3678
203	V	A	0.0000
204	N	A	-1.9729
205	H	A	0.0000
206	K	A	-2.7775
207	P	A	-1.5931
208	S	A	-1.8332
209	N	A	-2.6188
210	T	A	-2.1024
211	K	A	-2.6056
212	V	A	-1.3135
213	D	A	-2.0347
214	K	A	-1.8235
215	K	A	-2.5067
216	V	A	0.0000
217	E	A	-2.4813
218	P	A	-1.4547