Project name: 4c4577ff3fadae4

Chain sequence(s)	A: MRSEGLSLGLVLLCLLRVQAKPLGTAEPDASKVAGTWYITAMASDSKTYLEKKDQLKMAMANIEVLGDGDLNVSFAIPTPERCMKFSSIYKPTGNPDEYHSSDRGNKTVQLVNTDSSSYMVVFATREKNGKKLKMLRLYSRAQQVRPKIISLFKRFAKQYGFTDETIWILPTQEECQLGEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4343
• Maximal score value: 1.8368
• Average score: -0.8829
• Total score value: -159.7986

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	-0.1383
2	R	A	-1.9862
3	S	A	-1.6388
4	E	A	-2.2709
5	G	A	-1.0246
6	L	A	0.0647
7	S	A	-0.1981
8	L	A	0.0000
9	G	A	0.6837
10	L	A	1.8368
11	V	A	0.9538
12	L	A	0.0000
13	L	A	0.7176
14	C	A	0.5299
15	L	A	-0.1680
16	L	A	0.0000
17	R	A	-1.3605
18	V	A	-0.9456
19	Q	A	-1.8329
20	A	A	-1.6279
21	K	A	-1.9307
22	P	A	-1.1758
23	L	A	-0.7624
24	G	A	-0.9660
25	T	A	-0.2322
26	A	A	-0.9516
27	E	A	-2.4198
28	P	A	-2.2640
29	D	A	-2.8192
30	A	A	-1.8593
31	S	A	-1.6895
32	K	A	-2.5303
33	V	A	0.0000
34	A	A	-1.4260
35	G	A	-1.0787
36	T	A	-0.6881
37	W	A	0.0000
38	Y	A	-0.7011
39	I	A	0.0000
40	T	A	0.0000
41	A	A	0.0000
42	M	A	0.0000
43	A	A	0.0000
44	S	A	0.0000
45	D	A	-1.7126
46	S	A	-1.1716
47	K	A	-1.4770
48	T	A	-1.3566
49	Y	A	0.0000
50	L	A	0.0000
51	E	A	-2.0113
52	K	A	-2.9116
53	K	A	-2.5484
54	D	A	-1.9748
55	Q	A	-1.6875
56	L	A	0.0000
57	K	A	0.0000
58	M	A	0.0000
59	A	A	0.0000
60	M	A	0.0000
61	A	A	0.0000
62	N	A	-1.0247
63	I	A	0.0000
64	E	A	-1.6311
65	V	A	-0.5241
66	L	A	-0.2701
67	G	A	-0.9101
68	D	A	-1.9430
69	G	A	-1.2024
70	D	A	0.0000
71	L	A	0.0000
72	N	A	-0.2060
73	V	A	0.0000
74	S	A	-0.2571
75	F	A	0.0000
76	A	A	0.0000
77	I	A	-0.7312
78	P	A	0.0000
79	T	A	-1.8955
80	P	A	-2.0480
81	E	A	-3.2139
82	R	A	-2.7642
83	C	A	-1.3005
84	M	A	-0.6617
85	K	A	-0.8202
86	F	A	1.1027
87	S	A	0.6590
88	S	A	0.9425
89	I	A	1.2284
90	Y	A	0.2953
91	K	A	-1.0322
92	P	A	-1.2990
93	T	A	-1.2491
94	G	A	-1.2760
95	N	A	-1.8613
96	P	A	-1.6693
97	D	A	-1.5537
98	E	A	-1.3034
99	Y	A	-0.8336
100	H	A	-0.9533
101	S	A	0.0000
102	S	A	-1.2973
103	D	A	-1.5677
104	R	A	-2.6281
105	G	A	-2.5312
106	N	A	-2.5276
107	K	A	0.0000
108	T	A	-0.8306
109	V	A	0.0000
110	Q	A	-0.5581
111	L	A	-0.2780
112	V	A	0.0000
113	N	A	0.0000
114	T	A	-0.4497
115	D	A	0.0000
116	S	A	-1.0840
117	S	A	-0.6565
118	S	A	-0.6917
119	Y	A	0.0000
120	M	A	0.0000
121	V	A	0.0000
122	V	A	0.0000
123	F	A	0.1775
124	A	A	0.0000
125	T	A	-1.1103
126	R	A	0.0000
127	E	A	-3.0407
128	K	A	-3.1590
129	N	A	-2.6867
130	G	A	-2.4882
131	K	A	-3.4343
132	K	A	-3.3655
133	L	A	-1.5004
134	K	A	0.0000
135	M	A	0.0000
136	L	A	0.0000
137	R	A	0.0000
138	L	A	0.0000
139	Y	A	0.0000
140	S	A	0.0000
141	R	A	-0.8665
142	A	A	-0.9122
143	Q	A	-1.6181
144	Q	A	-1.5758
145	V	A	0.0000
146	R	A	-2.5443
147	P	A	-1.9047
148	K	A	-2.2697
149	I	A	-1.2989
150	I	A	-1.0630
151	S	A	-1.3969
152	L	A	0.0000
153	F	A	0.0000
154	K	A	-1.9601
155	R	A	-2.2229
156	F	A	0.0000
157	A	A	0.0000
158	K	A	-2.7411
159	Q	A	-1.7589
160	Y	A	-1.3010
161	G	A	-1.5538
162	F	A	0.0000
163	T	A	-2.0907
164	D	A	-2.2367
165	E	A	-2.3385
166	T	A	-1.7332
167	I	A	-0.9745
168	W	A	0.0000
169	I	A	0.5685
170	L	A	0.0000
171	P	A	-0.8468
172	T	A	-0.6822
173	Q	A	-1.7362
174	E	A	-2.4760
175	E	A	-1.5519
176	C	A	0.0000
177	Q	A	-1.1320
178	L	A	0.5595
179	G	A	-0.2081
180	E	A	-0.7847
181	P	A	-0.4809