Project name: 1s78:D

Chain sequence(s)	D: EVQLVESGGGLVQPGGSLRLSCAASGFTFTDYTMDWVRQAPGKGLEWVADVNPNSGGSIYNQRFKGRFTLSVDRSKNTLYLQMNSLRAEDTAVYYCARNLGPSFYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1306
• Maximal score value: 2.415
• Average score: -0.5588
• Total score value: -124.0635

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	D	-2.1304
2	V	D	-1.1434
3	Q	D	-1.3909
4	L	D	0.0000
5	V	D	0.1032
6	E	D	0.0000
7	S	D	-0.5661
8	G	D	-0.9600
9	G	D	-0.4995
10	G	D	-0.2421
11	L	D	0.0363
12	V	D	0.0000
13	Q	D	-1.7626
14	P	D	-1.7463
15	G	D	-1.5985
16	G	D	-1.2544
17	S	D	-1.1736
18	L	D	-1.1077
19	R	D	-2.0916
20	L	D	0.0000
21	S	D	-0.4849
22	C	D	0.0000
23	A	D	-0.7071
24	A	D	0.0000
25	S	D	-1.1735
26	G	D	-1.2621
27	F	D	-0.7366
28	T	D	-0.6107
29	F	D	0.0000
30	T	D	-1.6365
31	D	D	-1.8788
32	Y	D	-0.8189
33	T	D	0.0000
34	M	D	0.0000
35	D	D	0.0000
36	W	D	0.0000
37	V	D	0.0000
38	R	D	0.0000
39	Q	D	-0.3390
40	A	D	-1.0088
41	P	D	-1.0386
42	G	D	-1.5692
43	K	D	-2.0488
44	G	D	-0.8761
45	L	D	0.7741
46	E	D	0.0493
47	W	D	0.6153
48	V	D	0.0000
49	A	D	0.0000
50	D	D	0.0000
51	V	D	0.0000
52	N	D	-0.8877
52A	P	D	0.0000
53	N	D	-2.0854
54	S	D	-1.1526
55	G	D	-1.2788
56	G	D	-0.3277
57	S	D	0.7280
58	I	D	1.9964
59	Y	D	0.5091
60	N	D	-1.0242
61	Q	D	-2.4060
62	R	D	-2.9425
63	F	D	0.0000
64	K	D	-2.8472
65	G	D	-1.8962
66	R	D	-1.6123
67	F	D	0.0000
68	T	D	-0.7964
69	L	D	0.0000
70	S	D	-0.4943
71	V	D	-1.2573
72	D	D	-2.0319
73	R	D	-3.1306
74	S	D	-2.1992
75	K	D	-2.7767
76	N	D	-2.1742
77	T	D	0.0000
78	L	D	0.0000
79	Y	D	-0.4474
80	L	D	0.0000
81	Q	D	-1.1226
82	M	D	0.0000
82A	N	D	-1.5983
82B	S	D	-1.4692
82C	L	D	0.0000
83	R	D	-2.8865
84	A	D	-1.9624
85	E	D	-2.3508
86	D	D	0.0000
87	T	D	-0.7940
88	A	D	0.0000
89	V	D	0.4725
90	Y	D	0.0000
91	Y	D	0.4126
92	C	D	0.0000
93	A	D	0.0000
94	R	D	0.0000
95	N	D	0.0000
96	L	D	0.7207
97	G	D	0.3050
98	P	D	0.0522
99	S	D	0.6213
99A	F	D	1.7289
99B	Y	D	1.8313
100	F	D	1.2531
101	D	D	0.3932
102	Y	D	0.6602
103	W	D	0.4712
104	G	D	-0.2383
105	Q	D	-0.8816
106	G	D	-0.2226
107	T	D	0.0384
108	L	D	0.5153
109	V	D	0.0000
110	T	D	0.0000
111	V	D	0.0000
112	S	D	-0.8449
113	S	D	-0.8550
114	A	D	-0.5249
115	S	D	-0.6350
116	T	D	-0.5946
117	K	D	-1.1371
118	G	D	-1.4630
119	P	D	0.0000
120	S	D	-0.1909
121	V	D	0.0000
122	F	D	1.4056
123	P	D	0.2667
124	L	D	0.4504
125	A	D	-0.8699
126	P	D	-1.0211
127	S	D	-1.1386
128	S	D	-1.3410
129	K	D	-1.9653
130	S	D	-1.2393
131	T	D	-1.0960
132	S	D	-0.8216
133	G	D	-0.7410
134	G	D	-0.7084
135	T	D	-0.5629
136	A	D	-0.5760
137	A	D	0.0513
138	L	D	0.0000
139	G	D	0.0000
140	C	D	0.0000
141	L	D	0.8104
142	V	D	0.0000
143	K	D	-1.0056
144	D	D	-1.1474
145	Y	D	0.0000
146	F	D	0.0000
147	P	D	0.0000
148	E	D	-0.5256
149	P	D	-0.8934
150	V	D	0.0000
151	T	D	-0.5345
152	V	D	-0.5839
153	S	D	-0.2336
154	W	D	0.0000
155	N	D	-0.7295
156	S	D	-0.6752
157	G	D	-0.6152
158	A	D	-0.2440
159	L	D	-0.0444
160	T	D	-0.2888
161	S	D	-0.3484
162	G	D	-0.4153
163	V	D	-0.0987
164	H	D	-0.4871
165	T	D	0.1886
166	F	D	1.1210
167	P	D	0.5643
168	A	D	1.1341
169	V	D	2.4150
170	L	D	1.8252
171	Q	D	0.4545
172	S	D	0.0277
173	S	D	-0.2539
174	G	D	0.1361
175	L	D	-0.0104
176	Y	D	0.3144
177	S	D	0.2618
178	L	D	0.0000
179	S	D	0.4400
180	S	D	0.0000
181	V	D	0.4369
182	V	D	0.0000
183	T	D	-0.2327
184	V	D	0.0000
185	P	D	-0.4070
186	S	D	-0.4875
187	S	D	-0.4390
188	S	D	-0.5629
189	L	D	-0.6875
190	G	D	-1.0662
191	T	D	-1.0265
192	Q	D	-1.4557
193	T	D	-1.2724
194	Y	D	0.0000
195	I	D	-1.3352
196	C	D	0.0000
197	N	D	-1.5285
198	V	D	0.0000
199	N	D	-1.8993
200	H	D	0.0000
201	K	D	-2.6437
202	P	D	-1.6076
203	S	D	-1.8461
204	N	D	-2.3149
205	T	D	-2.1070
206	K	D	-2.6436
207	V	D	-1.3366
208	D	D	-2.4933
209	K	D	-2.1654
210	K	D	-2.5490
211	V	D	0.0000
212	E	D	-2.9180
213	P	D	-1.9027
214	K	D	-2.1499
215	S	D	-0.9760
216	C	D	0.0121