Project name: 5g64:H
Status: done
submitted: 2019-03-20 15:52:50, status changed: 2019-03-20 17:27:49
Settings
|
Chain sequence(s)
|
H: VQLVESGGGLVQPGGSLRLSCAVSGYSITSGYSWNWIRQAPGKGLEWVASITYDGSTNYNPSVKGRITISRDDSKNTFYLQMNSLRAEDTAVYYCARGSHYFGHWHFAVWGQGTLVTVSSASTKGPSVFPLAPGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8219
-
Maximal score value
-
2.2877
-
Average score
-
-0.5136
-
Total score value
-
-110.9391
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
V |
H |
1.1712 |
|
| 3 |
Q |
H |
-0.1056 |
|
| 4 |
L |
H |
0.0000 |
|
| 5 |
V |
H |
0.5189 |
|
| 6 |
E |
H |
-0.0704 |
|
| 7 |
S |
H |
-0.6381 |
|
| 8 |
G |
H |
-1.0126 |
|
| 9 |
G |
H |
-0.9313 |
|
| 10 |
G |
H |
-0.4625 |
|
| 11 |
L |
H |
-0.0307 |
|
| 12 |
V |
H |
-0.4701 |
|
| 13 |
Q |
H |
-1.5676 |
|
| 14 |
P |
H |
-1.5562 |
|
| 15 |
G |
H |
-1.5612 |
|
| 16 |
G |
H |
-1.1972 |
|
| 17 |
S |
H |
-1.3612 |
|
| 18 |
L |
H |
0.0000 |
|
| 19 |
R |
H |
-2.3192 |
|
| 20 |
L |
H |
0.0000 |
|
| 21 |
S |
H |
-0.6451 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
A |
H |
-0.3137 |
|
| 24 |
V |
H |
0.0000 |
|
| 25 |
S |
H |
-0.0828 |
|
| 26 |
G |
H |
0.0971 |
|
| 27 |
Y |
H |
0.4817 |
|
| 28 |
S |
H |
-0.3278 |
|
| 29 |
I |
H |
0.0000 |
|
| 30 |
T |
H |
-0.7255 |
|
| 31 |
S |
H |
-0.0899 |
|
| 32 |
G |
H |
0.0277 |
|
| 33 |
Y |
H |
0.0927 |
|
| 34 |
S |
H |
0.0000 |
|
| 35 |
W |
H |
0.0000 |
|
| 36 |
N |
H |
-0.0307 |
|
| 37 |
W |
H |
0.0000 |
|
| 38 |
I |
H |
0.0000 |
|
| 39 |
R |
H |
0.0000 |
|
| 40 |
Q |
H |
-0.3877 |
|
| 41 |
A |
H |
-1.1905 |
|
| 42 |
P |
H |
-1.1162 |
|
| 43 |
G |
H |
-1.4198 |
|
| 44 |
K |
H |
-2.1481 |
|
| 45 |
G |
H |
-1.1612 |
|
| 46 |
L |
H |
0.1947 |
|
| 47 |
E |
H |
-0.4267 |
|
| 48 |
W |
H |
0.7737 |
|
| 49 |
V |
H |
0.0000 |
|
| 50 |
A |
H |
0.0000 |
|
| 51 |
S |
H |
-0.3778 |
|
| 52 |
I |
H |
0.0000 |
|
| 53 |
T |
H |
-0.3875 |
|
| 54 |
Y |
H |
-0.1498 |
|
| 55 |
D |
H |
-1.3948 |
|
| 56 |
G |
H |
-1.0167 |
|
| 57 |
S |
H |
-0.8477 |
|
| 58 |
T |
H |
-0.8624 |
|
| 59 |
N |
H |
-1.4840 |
|
| 60 |
Y |
H |
-0.9684 |
|
| 61 |
N |
H |
-0.9704 |
|
| 62 |
P |
H |
-1.0175 |
|
| 63 |
S |
H |
-0.9174 |
|
| 64 |
V |
H |
0.0000 |
|
| 65 |
K |
H |
-2.2978 |
|
| 66 |
G |
H |
-1.5978 |
|
| 67 |
R |
H |
-1.4544 |
|
| 68 |
I |
H |
0.0000 |
|
| 69 |
T |
H |
-0.9141 |
|
| 70 |
I |
H |
0.0000 |
|
| 71 |
S |
H |
-0.7810 |
|
| 72 |
R |
H |
-1.7286 |
|
| 73 |
D |
H |
-2.2873 |
|
| 74 |
D |
H |
-2.8207 |
|
| 75 |
S |
H |
-2.2581 |
|
| 76 |
K |
H |
-2.7673 |
|
| 77 |
N |
H |
-2.1497 |
|
| 78 |
T |
H |
0.0000 |
|
| 79 |
F |
H |
0.0000 |
|
| 80 |
Y |
H |
-0.7956 |
|
| 81 |
L |
H |
0.0000 |
|
| 82 |
Q |
H |
-1.5765 |
|
| 83 |
M |
H |
0.0000 |
|
| 84 |
N |
H |
-1.6576 |
|
| 85 |
S |
H |
-1.4706 |
|
| 86 |
L |
H |
0.0000 |
|
| 87 |
R |
H |
-2.8219 |
|
| 88 |
A |
H |
-1.9628 |
|
| 89 |
E |
H |
-2.4135 |
|
| 90 |
D |
H |
0.0000 |
|
| 91 |
T |
H |
-0.8266 |
|
| 92 |
A |
H |
0.0000 |
|
| 93 |
V |
H |
0.2787 |
|
| 94 |
Y |
H |
0.0000 |
|
| 95 |
Y |
H |
0.3931 |
|
| 96 |
C |
H |
0.0000 |
|
| 97 |
A |
H |
0.0000 |
|
| 98 |
R |
H |
-0.0885 |
|
| 99 |
G |
H |
0.0000 |
|
| 100 |
S |
H |
-0.3817 |
|
| 101 |
H |
H |
-0.1421 |
|
| 102 |
Y |
H |
1.3296 |
|
| 103 |
F |
H |
1.9407 |
|
| 104 |
G |
H |
0.3544 |
|
| 105 |
H |
H |
-0.2511 |
|
| 106 |
W |
H |
0.0909 |
|
| 107 |
H |
H |
-0.6579 |
|
| 108 |
F |
H |
-0.0252 |
|
| 109 |
A |
H |
0.2285 |
|
| 110 |
V |
H |
0.5177 |
|
| 111 |
W |
H |
0.4314 |
|
| 112 |
G |
H |
-0.1932 |
|
| 113 |
Q |
H |
-0.9375 |
|
| 114 |
G |
H |
-0.3219 |
|
| 115 |
T |
H |
-0.2117 |
|
| 116 |
L |
H |
0.0421 |
|
| 117 |
V |
H |
0.0000 |
|
| 118 |
T |
H |
-0.3562 |
|
| 119 |
V |
H |
0.0000 |
|
| 120 |
S |
H |
-0.7709 |
|
| 121 |
S |
H |
-0.5823 |
|
| 122 |
A |
H |
-0.4091 |
|
| 123 |
S |
H |
-0.5292 |
|
| 124 |
T |
H |
-0.5217 |
|
| 125 |
K |
H |
-1.0799 |
|
| 126 |
G |
H |
-1.4375 |
|
| 127 |
P |
H |
-0.5962 |
|
| 128 |
S |
H |
-0.0317 |
|
| 129 |
V |
H |
0.4479 |
|
| 130 |
F |
H |
1.7422 |
|
| 131 |
P |
H |
0.5736 |
|
| 132 |
L |
H |
0.3208 |
|
| 133 |
A |
H |
-0.8548 |
|
| 134 |
P |
H |
-0.8427 |
|
| 141 |
G |
H |
-0.7598 |
|
| 142 |
G |
H |
-0.8551 |
|
| 143 |
T |
H |
-0.5925 |
|
| 144 |
A |
H |
-0.3837 |
|
| 145 |
A |
H |
0.0295 |
|
| 146 |
L |
H |
0.0000 |
|
| 147 |
G |
H |
0.0000 |
|
| 148 |
C |
H |
0.0000 |
|
| 149 |
L |
H |
0.8348 |
|
| 150 |
V |
H |
0.0000 |
|
| 151 |
K |
H |
-0.5728 |
|
| 152 |
D |
H |
-1.1784 |
|
| 153 |
Y |
H |
0.0000 |
|
| 154 |
F |
H |
0.0000 |
|
| 155 |
P |
H |
0.0000 |
|
| 156 |
E |
H |
-0.8004 |
|
| 157 |
P |
H |
-0.7817 |
|
| 158 |
V |
H |
-0.4331 |
|
| 159 |
T |
H |
-0.4762 |
|
| 160 |
V |
H |
-0.0238 |
|
| 161 |
S |
H |
-0.2689 |
|
| 162 |
W |
H |
0.0000 |
|
| 163 |
N |
H |
-0.6527 |
|
| 164 |
S |
H |
-0.6034 |
|
| 165 |
G |
H |
-0.5010 |
|
| 166 |
A |
H |
-0.1845 |
|
| 167 |
L |
H |
0.0330 |
|
| 168 |
T |
H |
-0.2329 |
|
| 169 |
S |
H |
-0.3241 |
|
| 170 |
G |
H |
-0.3976 |
|
| 171 |
V |
H |
0.0647 |
|
| 172 |
H |
H |
-0.5554 |
|
| 173 |
T |
H |
0.0319 |
|
| 174 |
F |
H |
0.7522 |
|
| 175 |
P |
H |
0.4545 |
|
| 176 |
A |
H |
1.0721 |
|
| 177 |
V |
H |
2.2877 |
|
| 178 |
L |
H |
1.8500 |
|
| 179 |
Q |
H |
-0.0634 |
|
| 180 |
S |
H |
-0.3454 |
|
| 181 |
S |
H |
-0.5635 |
|
| 182 |
G |
H |
-0.1936 |
|
| 183 |
L |
H |
-0.0308 |
|
| 184 |
Y |
H |
0.4969 |
|
| 185 |
S |
H |
0.0000 |
|
| 186 |
L |
H |
0.0000 |
|
| 187 |
S |
H |
0.5997 |
|
| 188 |
S |
H |
0.0000 |
|
| 189 |
V |
H |
0.3953 |
|
| 190 |
V |
H |
0.0000 |
|
| 191 |
T |
H |
-0.2160 |
|
| 192 |
V |
H |
0.0000 |
|
| 193 |
P |
H |
-0.5307 |
|
| 194 |
S |
H |
-0.5952 |
|
| 195 |
S |
H |
-0.5928 |
|
| 196 |
S |
H |
-0.5975 |
|
| 197 |
L |
H |
-0.7880 |
|
| 198 |
G |
H |
-1.0089 |
|
| 199 |
T |
H |
-0.7614 |
|
| 200 |
Q |
H |
-1.3267 |
|
| 201 |
T |
H |
-1.0990 |
|
| 202 |
Y |
H |
0.0000 |
|
| 203 |
I |
H |
-1.0761 |
|
| 204 |
C |
H |
0.0000 |
|
| 205 |
N |
H |
-1.3314 |
|
| 206 |
V |
H |
0.0000 |
|
| 207 |
N |
H |
-1.7227 |
|
| 208 |
H |
H |
0.0000 |
|
| 209 |
K |
H |
-2.7028 |
|
| 210 |
P |
H |
-1.5488 |
|
| 211 |
S |
H |
-1.7047 |
|
| 212 |
N |
H |
-2.4171 |
|
| 213 |
T |
H |
-2.0278 |
|
| 214 |
K |
H |
-2.5875 |
|
| 215 |
V |
H |
-1.4745 |
|
| 216 |
D |
H |
-2.3785 |
|
| 217 |
K |
H |
-1.6975 |
|
| 218 |
K |
H |
-2.1867 |
|
| 219 |
V |
H |
0.0000 |
|
| 220 |
E |
H |
-2.7694 |
|
| 221 |
P |
H |
-1.8620 |
|
| 222 |
K |
H |
-2.2739 |
|
| 223 |
S |
H |
-1.2895 |
|