| Chain sequence(s) |
A: GPLGSEDDLYRQSLEIISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVTNWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFFHVQDLEGG B: AELPPEFAAQLRKIGDKVYCTWSAPDM |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 147 | G | A | -1.2156 | |
| 148 | P | A | -0.6584 | |
| 149 | L | A | 0.5153 | |
| 150 | G | A | -0.4835 | |
| 151 | S | A | -0.9738 | |
| 152 | E | A | -2.1080 | |
| 153 | D | A | -2.0664 | |
| 154 | D | A | -2.6074 | |
| 155 | L | A | -1.8080 | |
| 156 | Y | A | -2.0839 | |
| 157 | R | A | -2.6106 | |
| 158 | Q | A | -1.6178 | |
| 159 | S | A | 0.0000 | |
| 160 | L | A | -1.1725 | |
| 161 | E | A | -1.1785 | |
| 162 | I | A | 0.0000 | |
| 163 | I | A | 0.0000 | |
| 164 | S | A | -0.9210 | |
| 165 | R | A | -0.9634 | |
| 166 | Y | A | 0.0000 | |
| 167 | L | A | 0.0000 | |
| 168 | R | A | -1.5228 | |
| 169 | E | A | 0.0000 | |
| 170 | Q | A | -1.3393 | |
| 171 | A | A | 0.0000 | |
| 172 | T | A | -1.1690 | |
| 173 | G | A | -1.3679 | |
| 174 | S | A | -1.5672 | |
| 175 | K | A | -2.3699 | |
| 176 | D | A | -2.1970 | |
| 177 | S | A | -2.1582 | |
| 178 | K | A | -1.7903 | |
| 179 | P | A | -1.3392 | |
| 180 | L | A | -1.1407 | |
| 181 | G | A | -0.9456 | |
| 182 | E | A | -1.4846 | |
| 183 | A | A | 0.0000 | |
| 184 | G | A | -1.0693 | |
| 185 | A | A | -0.8742 | |
| 186 | A | A | -1.2240 | |
| 187 | G | A | 0.0000 | |
| 188 | R | A | -2.8074 | |
| 189 | R | A | -2.1859 | |
| 190 | A | A | 0.0000 | |
| 191 | L | A | 0.0000 | |
| 192 | E | A | -3.0815 | |
| 193 | T | A | 0.0000 | |
| 194 | L | A | 0.0000 | |
| 195 | R | A | -2.1840 | |
| 196 | R | A | -2.5240 | |
| 197 | V | A | 0.0000 | |
| 198 | G | A | 0.0000 | |
| 199 | D | A | -1.7758 | |
| 200 | G | A | -1.7674 | |
| 201 | V | A | 0.0000 | |
| 202 | Q | A | 0.0000 | |
| 203 | R | A | -2.7812 | |
| 204 | N | A | -2.4420 | |
| 205 | H | A | -1.8012 | |
| 206 | E | A | -2.0317 | |
| 207 | T | A | -1.2826 | |
| 208 | A | A | -1.2630 | |
| 209 | F | A | 0.0000 | |
| 210 | Q | A | -2.1052 | |
| 211 | G | A | -1.8330 | |
| 212 | M | A | 0.0000 | |
| 213 | L | A | -1.8301 | |
| 214 | R | A | -2.8711 | |
| 215 | K | A | -2.5488 | |
| 216 | L | A | -2.0687 | |
| 217 | D | A | -2.3791 | |
| 218 | I | A | 0.0000 | |
| 219 | K | A | -2.5843 | |
| 220 | N | A | -2.6504 | |
| 221 | E | A | -2.9013 | |
| 222 | G | A | -2.2170 | |
| 223 | D | A | -2.0757 | |
| 224 | V | A | -2.0862 | |
| 225 | K | A | -2.5218 | |
| 226 | S | A | -1.5190 | |
| 227 | F | A | 0.0000 | |
| 228 | S | A | 0.0000 | |
| 229 | R | A | -2.2475 | |
| 230 | V | A | 0.0000 | |
| 231 | M | A | 0.0000 | |
| 232 | V | A | -1.0093 | |
| 233 | H | A | -1.8113 | |
| 234 | V | A | 0.0000 | |
| 235 | F | A | -1.2373 | |
| 236 | K | A | -2.5812 | |
| 237 | D | A | -2.5841 | |
| 238 | G | A | -1.3412 | |
| 239 | V | A | -0.0096 | |
| 240 | T | A | -0.0200 | |
| 241 | N | A | 0.1859 | |
| 242 | W | A | 0.0000 | |
| 243 | G | A | 0.0000 | |
| 244 | R | A | 0.0000 | |
| 245 | I | A | 0.0000 | |
| 246 | V | A | 0.0000 | |
| 247 | T | A | 0.0000 | |
| 248 | L | A | 0.0000 | |
| 249 | I | A | 0.0000 | |
| 250 | S | A | 0.0000 | |
| 251 | F | A | 0.0000 | |
| 252 | G | A | 0.0000 | |
| 253 | A | A | 0.0000 | |
| 254 | F | A | 0.0000 | |
| 255 | V | A | 0.0000 | |
| 256 | A | A | 0.0000 | |
| 257 | K | A | -1.0403 | |
| 258 | H | A | -1.0414 | |
| 259 | L | A | 0.0000 | |
| 260 | K | A | -1.1381 | |
| 261 | S | A | -0.3711 | |
| 262 | V | A | 0.6067 | |
| 263 | N | A | -1.0633 | |
| 264 | Q | A | -1.3581 | |
| 265 | E | A | -1.3708 | |
| 266 | S | A | -1.2401 | |
| 267 | F | A | -1.6748 | |
| 268 | I | A | 0.0000 | |
| 269 | E | A | -1.6650 | |
| 270 | P | A | -1.5955 | |
| 271 | L | A | 0.0000 | |
| 272 | A | A | 0.0000 | |
| 273 | E | A | -2.3695 | |
| 274 | T | A | -1.8318 | |
| 275 | I | A | 0.0000 | |
| 276 | T | A | 0.0000 | |
| 277 | D | A | -2.2845 | |
| 278 | V | A | -1.9577 | |
| 279 | L | A | 0.0000 | |
| 280 | V | A | 0.0000 | |
| 281 | R | A | -2.8842 | |
| 282 | T | A | -1.6488 | |
| 283 | K | A | 0.0000 | |
| 284 | R | A | -3.1328 | |
| 285 | D | A | -3.0006 | |
| 286 | W | A | -1.7252 | |
| 287 | L | A | 0.0000 | |
| 288 | V | A | -1.7484 | |
| 289 | K | A | -2.6823 | |
| 290 | Q | A | -2.4073 | |
| 291 | R | A | -2.4493 | |
| 292 | G | A | 0.0000 | |
| 293 | W | A | 0.0000 | |
| 294 | D | A | -1.5072 | |
| 295 | G | A | -1.3571 | |
| 296 | F | A | 0.0000 | |
| 297 | V | A | 0.0000 | |
| 298 | E | A | -0.6362 | |
| 299 | F | A | -0.1457 | |
| 300 | F | A | 0.0000 | |
| 301 | H | A | 0.0000 | |
| 302 | V | A | -0.7799 | |
| 303 | Q | A | -1.6138 | |
| 304 | D | A | -1.9505 | |
| 305 | L | A | -0.1879 | |
| 306 | E | A | -1.0802 | |
| 307 | G | A | -1.1034 | |
| 308 | G | A | -0.9096 | |
| 17 | A | B | -1.1282 | |
| 18 | E | B | -1.9415 | |
| 19 | L | B | -0.9130 | |
| 20 | P | B | -0.7949 | |
| 21 | P | B | -0.8504 | |
| 22 | E | B | -0.8339 | |
| 23 | F | B | 0.0000 | |
| 24 | A | B | -1.2511 | |
| 25 | A | B | -1.0564 | |
| 26 | Q | B | -1.1572 | |
| 27 | L | B | 0.0000 | |
| 28 | R | B | -2.3746 | |
| 29 | K | B | -2.2916 | |
| 30 | I | B | 0.0000 | |
| 31 | G | B | 0.0000 | |
| 32 | D | B | -1.4513 | |
| 33 | K | B | -1.9497 | |
| 34 | V | B | 0.0000 | |
| 35 | Y | B | -0.0741 | |
| 36 | C | B | 0.1839 | |
| 37 | T | B | -0.2487 | |
| 38 | W | B | -0.0041 | |
| 39 | S | B | 0.0236 | |
| 40 | A | B | 0.0021 | |
| 41 | P | B | -0.9730 | |
| 42 | D | B | -1.6379 | |
| 43 | M | B | 0.0720 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine