Project name: 5icz:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9075
• Maximal score value: 2.5115
• Average score: -0.5179
• Total score value: -111.8706

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4179
2	V	B	-0.7681
3	Q	B	-1.3214
4	L	B	0.0000
5	K	B	-1.7237
6	Q	B	0.0000
7	S	B	-0.7272
8	G	B	-0.9535
9	P	B	-0.3671
10	G	B	-0.3583
11	L	B	-0.1604
12	V	B	0.0000
13	Q	B	-1.7250
14	P	B	-1.5200
15	S	B	-1.5465
16	Q	B	-1.8810
17	S	B	-1.4597
18	L	B	0.0000
19	S	B	-0.5142
20	I	B	0.0000
21	T	B	-0.4340
22	C	B	0.0000
23	T	B	-0.9707
24	V	B	0.0000
25	S	B	-0.9316
26	G	B	-0.9428
27	F	B	-0.5157
28	S	B	-0.9832
29	L	B	0.0000
30	T	B	-1.0038
31	N	B	-0.9166
32	Y	B	0.4022
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.3335
40	S	B	-0.9592
41	P	B	-1.1186
42	G	B	-1.6532
43	K	B	-2.0228
44	G	B	-0.6327
45	L	B	0.7838
46	E	B	0.0000
47	W	B	0.4622
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.4409
53	S	B	-0.7035
54	G	B	-1.2570
55	G	B	-1.5466
56	N	B	-1.9334
57	T	B	-1.4971
58	D	B	-1.5089
59	Y	B	-0.6726
60	N	B	-0.6194
61	T	B	-0.5171
62	P	B	-0.4614
63	F	B	0.0000
64	T	B	-0.5966
65	S	B	-0.5599
66	R	B	-0.8542
67	L	B	0.0000
68	S	B	-0.9084
69	I	B	0.0000
70	N	B	-1.7533
71	K	B	-1.5540
72	D	B	-1.9500
73	N	B	-2.5961
74	S	B	-1.8747
75	K	B	-2.4628
76	S	B	-1.7219
77	Q	B	-1.5766
78	V	B	0.0000
79	F	B	-0.2757
80	F	B	0.0000
81	K	B	-1.1454
82	M	B	0.0000
83	N	B	-1.3707
84	S	B	-1.4059
85	L	B	0.0000
86	Q	B	-2.1662
87	S	B	-1.5798
88	N	B	-2.0957
89	D	B	0.0000
90	T	B	-0.7152
91	A	B	0.0000
92	I	B	0.5125
93	Y	B	0.0000
94	Y	B	-0.0344
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.3330
100	T	B	1.1871
101	Y	B	1.8910
102	Y	B	1.7325
103	D	B	0.7148
104	Y	B	0.6943
105	E	B	-0.4249
106	F	B	0.3481
107	A	B	0.5631
108	Y	B	0.4269
109	W	B	0.1493
110	G	B	0.0000
111	Q	B	-1.3543
112	G	B	-0.5441
113	T	B	0.0000
114	L	B	0.4133
115	V	B	0.0000
116	T	B	-0.3458
117	V	B	0.0000
118	S	B	-0.6447
119	A	B	-0.4229
120	A	B	-0.3578
121	S	B	-0.5860
122	T	B	-0.8094
123	K	B	-1.3444
124	G	B	-1.4942
125	P	B	-0.7039
126	S	B	-0.1792
127	V	B	0.0000
128	F	B	0.8967
129	P	B	-0.1490
130	L	B	0.3199
131	A	B	-0.9094
132	P	B	0.0000
133	S	B	-0.8005
138	S	B	-0.6500
139	G	B	-0.8591
140	G	B	-0.9350
141	T	B	-0.6567
142	A	B	-0.3949
143	A	B	0.0549
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.6194
148	V	B	0.0000
149	K	B	-0.2668
150	D	B	-0.6596
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.0652
155	P	B	-0.4651
156	V	B	-0.5606
157	T	B	-0.5652
158	V	B	-0.3013
159	S	B	-0.5570
160	W	B	0.0000
161	N	B	-0.9164
162	S	B	-0.7326
163	G	B	-0.5988
164	A	B	-0.2723
165	L	B	-0.0881
166	T	B	-0.3401
167	S	B	-0.3655
168	G	B	-0.4320
169	V	B	-0.1155
170	H	B	-0.5501
171	T	B	0.1741
172	F	B	1.0820
173	P	B	0.6467
174	A	B	1.3280
175	V	B	2.5115
176	L	B	2.1844
177	Q	B	0.6707
178	S	B	0.0742
179	S	B	-0.2261
180	G	B	0.2079
181	L	B	0.2725
182	Y	B	0.8413
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6407
186	S	B	0.0000
187	V	B	0.3684
188	V	B	0.0000
189	T	B	-0.2184
190	V	B	0.0000
191	P	B	-0.6918
192	S	B	-0.7493
193	S	B	-0.6648
194	S	B	-0.7576
195	L	B	-0.9054
196	G	B	-1.0512
197	T	B	-0.8782
198	Q	B	-1.5409
199	T	B	-1.3237
200	Y	B	0.0000
201	I	B	-1.6106
202	C	B	0.0000
203	N	B	-1.6194
204	V	B	0.0000
205	N	B	-2.0226
206	H	B	0.0000
207	K	B	-2.4364
208	P	B	-1.4651
209	S	B	-1.7608
210	N	B	-2.4709
211	T	B	-2.0582
212	K	B	-2.7428
213	V	B	-1.9656
214	D	B	-2.7565
215	K	B	-2.0824
216	R	B	-2.7310
217	V	B	0.0000
218	E	B	-2.9075
219	P	B	-1.8661
220	K	B	-2.2385