Project name: 5vl3:A
Status: done
submitted: 2019-03-20 16:13:10, status changed: 2019-03-20 17:31:27
Settings
|
Chain sequence(s)
|
A: QVQLVQSGAEVKKPGSSVKVSCKASGYTFTSYWLHWVRQAPGQGLEWIGYINPRNDYTEYNQNFKDKATITADESTNTAYMELSSLRSEDTAFYFCARRDITTFYWGQGTTVTVSSASTKGPSVFPLAPSSKGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5148
-
Maximal score value
-
1.9593
-
Average score
-
-0.624
-
Total score value
-
-133.5311
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
A |
-1.3247 |
|
| 2 |
V |
A |
-0.5696 |
|
| 3 |
Q |
A |
-0.7566 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
V |
A |
0.7557 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
-0.4050 |
|
| 8 |
G |
A |
-0.4203 |
|
| 9 |
A |
A |
-0.0227 |
|
| 10 |
E |
A |
-0.3232 |
|
| 11 |
V |
A |
0.1647 |
|
| 12 |
K |
A |
-1.2582 |
|
| 13 |
K |
A |
-2.2443 |
|
| 14 |
P |
A |
-1.9255 |
|
| 15 |
G |
A |
-1.5888 |
|
| 16 |
S |
A |
-1.3491 |
|
| 17 |
S |
A |
-1.3846 |
|
| 18 |
V |
A |
0.0000 |
|
| 19 |
K |
A |
-1.7163 |
|
| 20 |
V |
A |
0.0000 |
|
| 21 |
S |
A |
-0.3820 |
|
| 22 |
C |
A |
0.0000 |
|
| 23 |
K |
A |
-0.5172 |
|
| 24 |
A |
A |
0.0000 |
|
| 25 |
S |
A |
-0.6111 |
|
| 26 |
G |
A |
-0.7493 |
|
| 27 |
Y |
A |
-0.2492 |
|
| 28 |
T |
A |
-0.2861 |
|
| 29 |
F |
A |
0.0000 |
|
| 30 |
T |
A |
0.0000 |
|
| 31 |
S |
A |
-0.2979 |
|
| 32 |
Y |
A |
0.1451 |
|
| 33 |
W |
A |
0.1694 |
|
| 34 |
L |
A |
0.0000 |
|
| 35 |
H |
A |
-0.0744 |
|
| 36 |
W |
A |
0.0000 |
|
| 37 |
V |
A |
0.0000 |
|
| 38 |
R |
A |
-0.2328 |
|
| 39 |
Q |
A |
-0.4006 |
|
| 40 |
A |
A |
-0.9833 |
|
| 41 |
P |
A |
-1.0373 |
|
| 42 |
G |
A |
-1.3340 |
|
| 43 |
Q |
A |
-1.7558 |
|
| 44 |
G |
A |
-0.9754 |
|
| 45 |
L |
A |
0.2913 |
|
| 46 |
E |
A |
-1.0140 |
|
| 47 |
W |
A |
-0.2616 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
G |
A |
0.0000 |
|
| 50 |
Y |
A |
0.0000 |
|
| 51 |
I |
A |
0.0000 |
|
| 52 |
N |
A |
-1.1857 |
|
| 52A |
P |
A |
0.0000 |
|
| 53 |
R |
A |
-3.0850 |
|
| 54 |
N |
A |
-2.7275 |
|
| 55 |
D |
A |
-2.7567 |
|
| 56 |
Y |
A |
-0.6652 |
|
| 57 |
T |
A |
-0.5236 |
|
| 58 |
E |
A |
-1.3059 |
|
| 59 |
Y |
A |
-1.4991 |
|
| 60 |
N |
A |
-1.7472 |
|
| 61 |
Q |
A |
-2.7046 |
|
| 62 |
N |
A |
-2.7106 |
|
| 63 |
F |
A |
0.0000 |
|
| 64 |
K |
A |
-3.5148 |
|
| 65 |
D |
A |
-3.2283 |
|
| 66 |
K |
A |
-2.2113 |
|
| 67 |
A |
A |
0.0000 |
|
| 68 |
T |
A |
-1.2447 |
|
| 69 |
I |
A |
0.0000 |
|
| 70 |
T |
A |
-0.6440 |
|
| 71 |
A |
A |
-1.6237 |
|
| 72 |
D |
A |
-2.2521 |
|
| 73 |
E |
A |
-2.9587 |
|
| 74 |
S |
A |
-1.4713 |
|
| 75 |
T |
A |
-1.3005 |
|
| 76 |
N |
A |
-1.6632 |
|
| 77 |
T |
A |
-1.0166 |
|
| 78 |
A |
A |
0.0000 |
|
| 79 |
Y |
A |
-0.5297 |
|
| 80 |
M |
A |
0.0000 |
|
| 81 |
E |
A |
-1.5337 |
|
| 82 |
L |
A |
0.0000 |
|
| 82A |
S |
A |
-1.4413 |
|
| 82B |
S |
A |
-1.4419 |
|
| 82C |
L |
A |
0.0000 |
|
| 83 |
R |
A |
-2.9534 |
|
| 84 |
S |
A |
-2.1416 |
|
| 85 |
E |
A |
-2.5080 |
|
| 86 |
D |
A |
0.0000 |
|
| 87 |
T |
A |
-0.7465 |
|
| 88 |
A |
A |
0.0000 |
|
| 89 |
F |
A |
1.1920 |
|
| 90 |
Y |
A |
0.0000 |
|
| 91 |
F |
A |
0.6061 |
|
| 92 |
C |
A |
0.0000 |
|
| 93 |
A |
A |
0.0000 |
|
| 94 |
R |
A |
0.0000 |
|
| 95 |
R |
A |
-0.2678 |
|
| 96 |
D |
A |
0.5507 |
|
| 97 |
I |
A |
1.7493 |
|
| 98 |
T |
A |
0.8913 |
|
| 99 |
T |
A |
0.9259 |
|
| 101 |
F |
A |
1.6399 |
|
| 102 |
Y |
A |
0.6605 |
|
| 103 |
W |
A |
0.6412 |
|
| 104 |
G |
A |
0.0000 |
|
| 105 |
Q |
A |
-0.6208 |
|
| 106 |
G |
A |
0.0135 |
|
| 107 |
T |
A |
0.0000 |
|
| 108 |
T |
A |
0.4470 |
|
| 109 |
V |
A |
0.0000 |
|
| 110 |
T |
A |
0.0000 |
|
| 111 |
V |
A |
0.0000 |
|
| 112 |
S |
A |
0.0000 |
|
| 113 |
S |
A |
-0.9989 |
|
| 115 |
A |
A |
-0.6749 |
|
| 116 |
S |
A |
-0.6873 |
|
| 117 |
T |
A |
-0.9826 |
|
| 118 |
K |
A |
-1.7803 |
|
| 119 |
G |
A |
-1.7713 |
|
| 120 |
P |
A |
0.0000 |
|
| 121 |
S |
A |
-0.1075 |
|
| 122 |
V |
A |
0.0000 |
|
| 123 |
F |
A |
1.1015 |
|
| 124 |
P |
A |
0.1372 |
|
| 125 |
L |
A |
0.2443 |
|
| 126 |
A |
A |
-0.7481 |
|
| 127 |
P |
A |
0.0000 |
|
| 128 |
S |
A |
-1.2725 |
|
| 129 |
S |
A |
-1.1607 |
|
| 130 |
K |
A |
-1.8300 |
|
| 134 |
G |
A |
-0.8111 |
|
| 135 |
G |
A |
-0.8817 |
|
| 136 |
T |
A |
-0.5712 |
|
| 137 |
A |
A |
-0.5429 |
|
| 138 |
A |
A |
-0.0090 |
|
| 139 |
L |
A |
0.0000 |
|
| 140 |
G |
A |
0.0000 |
|
| 141 |
C |
A |
0.0000 |
|
| 142 |
L |
A |
0.7396 |
|
| 143 |
V |
A |
0.0000 |
|
| 144 |
K |
A |
-0.2688 |
|
| 145 |
D |
A |
-0.9692 |
|
| 146 |
Y |
A |
0.0000 |
|
| 147 |
F |
A |
0.0000 |
|
| 148 |
P |
A |
-0.8907 |
|
| 149 |
E |
A |
-1.1629 |
|
| 150 |
P |
A |
-1.2388 |
|
| 151 |
V |
A |
0.0000 |
|
| 152 |
T |
A |
-0.9663 |
|
| 153 |
V |
A |
-0.5346 |
|
| 154 |
S |
A |
-0.4830 |
|
| 155 |
W |
A |
0.0000 |
|
| 156 |
N |
A |
-0.9476 |
|
| 157 |
S |
A |
-0.5874 |
|
| 158 |
G |
A |
-0.4559 |
|
| 159 |
A |
A |
-0.2044 |
|
| 160 |
L |
A |
-0.0005 |
|
| 161 |
T |
A |
-0.2477 |
|
| 162 |
S |
A |
-0.3146 |
|
| 163 |
G |
A |
-0.3999 |
|
| 164 |
V |
A |
0.1393 |
|
| 165 |
H |
A |
-0.2659 |
|
| 166 |
T |
A |
0.3166 |
|
| 167 |
F |
A |
1.1051 |
|
| 168 |
P |
A |
0.6335 |
|
| 169 |
A |
A |
0.8941 |
|
| 170 |
V |
A |
1.9593 |
|
| 171 |
L |
A |
0.9628 |
|
| 172 |
Q |
A |
0.1825 |
|
| 173 |
S |
A |
-0.1592 |
|
| 174 |
S |
A |
-0.3698 |
|
| 175 |
G |
A |
0.0000 |
|
| 176 |
L |
A |
-0.2574 |
|
| 177 |
Y |
A |
0.0000 |
|
| 178 |
S |
A |
0.0000 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
S |
A |
0.6888 |
|
| 181 |
S |
A |
0.0000 |
|
| 182 |
V |
A |
0.5535 |
|
| 183 |
V |
A |
0.0000 |
|
| 184 |
T |
A |
-0.2153 |
|
| 185 |
V |
A |
0.0000 |
|
| 186 |
P |
A |
-0.5762 |
|
| 187 |
S |
A |
-0.5936 |
|
| 188 |
S |
A |
-0.4883 |
|
| 189 |
S |
A |
-0.5549 |
|
| 190 |
L |
A |
-0.6089 |
|
| 191 |
G |
A |
-1.2777 |
|
| 192 |
T |
A |
-1.0292 |
|
| 193 |
Q |
A |
-1.2847 |
|
| 194 |
T |
A |
-1.5124 |
|
| 195 |
Y |
A |
0.0000 |
|
| 196 |
I |
A |
-1.4116 |
|
| 197 |
C |
A |
0.0000 |
|
| 198 |
N |
A |
-1.4755 |
|
| 199 |
V |
A |
0.0000 |
|
| 200 |
N |
A |
-2.6177 |
|
| 201 |
H |
A |
0.0000 |
|
| 202 |
K |
A |
-3.0222 |
|
| 203 |
P |
A |
-1.9089 |
|
| 204 |
S |
A |
-2.0660 |
|
| 205 |
N |
A |
-2.7792 |
|
| 206 |
T |
A |
-2.3342 |
|
| 207 |
K |
A |
-2.7836 |
|
| 208 |
V |
A |
-1.4429 |
|
| 209 |
D |
A |
-2.1256 |
|
| 210 |
K |
A |
-1.8261 |
|
| 211 |
R |
A |
-2.5985 |
|
| 212 |
V |
A |
0.0000 |
|
| 213 |
E |
A |
-2.9124 |
|
| 214 |
P |
A |
-2.0495 |
|
| 215 |
K |
A |
-2.3072 |
|