| Chain sequence(s) |
A: NVEEETKYIELMIVNDHLMFKKHRLSVVHTNTYAKSVVNMADLIYKDQLKTRIVLVAMETWATDNKFAISENPLITLREFMKYRRDFIKEKSDAVHLFSGSQFESSRSGAAYIGGICSLLKGGGVNEFGKTDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDTGYYLPKKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAECVLEGAECCKKCTLTQDSQCSDGLCCKKCKFQPMGTVCREAVNDCDIRETCSGNSSQCAPNIHKMDGYSCDGVQGICFGGRCKTRDRQCKYIWGQKVTASDKYCYEKLNIEGTEKGNCGKDKDTWIQCNKRDVLCGYLLCTNIGNIPRLGELDGEITSTLVVQQGRTLNCSGGHVKLEEDVDLGYVEDGTPCGPQMMCLEHRCLPVASFNFSTCLSSKEGTICSGNGVCSNELKCVCNRHWIGSDCNTYFPHN B: NVEEETKYIELMIVNDHLMFKKHRLSVVHTNTYAKSVVNMADLIYKDQLKTRIVLVAMETWATDNKFAISENPLITLREFMKYRRDFIKEKSDAVHLFSGSQFESSRSGAAYIGGICSLLKGGGVNEFGKTDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDTGYYLPKKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAECVLEGAECCKKCTLTQDSQCSDGLCCKKCKFQPMGTVCREAVNDCDIRETCSGNSSQCAPNIHKMDGYSCDGVQGICFGGRCKTRDRQCKYIWGQKVTASDKYCYEKLNIEGTEKGNCGKDKDTWIQCNKRDVLCGYLLCTNIGNIPRLGELDGEITSTLVVQQGRTLNCSGGHVKLEEDVDLGYVEDGTPCGPQMMCLEHRCLPVASFNFSTCLSSKEGTICSGNGVCSNELKCVCNRHWIGSDCNTYFPHN |
| Distance of aggregation | 5 Å |
| Dynamic mode | No |
| Mutated residues | CA394Y |
| Energy difference between WT (input) and mutated protein (by FoldX) | 3.40232 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure Changes in protein stability upon mutation are calculated using the FoldX forcefield. Computational prediction of protein stability is used with the intention of preventing the experimental characterization of proteins bearing mutations that significantly destabilize their structure. Mutations resulting in a predicted reduction in protein stability ≥ 1 kcal/mol are considered disruptive. |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 233 | N | A | -1.2730 | |
| 234 | V | A | 0.0000 | |
| 235 | E | A | -0.8775 | |
| 236 | E | A | -1.9540 | |
| 237 | E | A | -0.5276 | |
| 238 | T | A | -0.0636 | |
| 239 | K | A | 0.0000 | |
| 240 | Y | A | 0.0879 | |
| 241 | I | A | 0.0000 | |
| 242 | E | A | -0.2526 | |
| 243 | L | A | 0.0000 | |
| 244 | M | A | 0.0000 | |
| 245 | I | A | 0.0000 | |
| 246 | V | A | 0.0000 | |
| 247 | N | A | 0.0000 | |
| 248 | D | A | 0.0000 | |
| 249 | H | A | 0.0030 | |
| 250 | L | A | 0.4275 | |
| 251 | M | A | 0.0000 | |
| 252 | F | A | 0.0000 | |
| 253 | K | A | -1.8780 | |
| 254 | K | A | -1.6480 | |
| 255 | H | A | -0.6913 | |
| 256 | R | A | -1.5832 | |
| 257 | L | A | 1.2059 | |
| 258 | S | A | 0.4735 | |
| 259 | V | A | 1.5418 | |
| 260 | V | A | 1.8914 | |
| 261 | H | A | -0.2534 | |
| 262 | T | A | 0.0000 | |
| 263 | N | A | -0.3626 | |
| 264 | T | A | -0.1311 | |
| 265 | Y | A | 0.1706 | |
| 266 | A | A | 0.0000 | |
| 267 | K | A | -0.3212 | |
| 268 | S | A | -0.2913 | |
| 269 | V | A | 0.0000 | |
| 270 | V | A | 0.0000 | |
| 271 | N | A | -1.1999 | |
| 272 | M | A | 0.2278 | |
| 273 | A | A | 0.0000 | |
| 274 | D | A | 0.0000 | |
| 275 | L | A | 1.0079 | |
| 276 | I | A | 0.0000 | |
| 277 | Y | A | 0.0000 | |
| 278 | K | A | -1.3913 | |
| 279 | D | A | -2.0676 | |
| 280 | Q | A | -0.6622 | |
| 281 | L | A | 0.0000 | |
| 282 | K | A | -1.1991 | |
| 283 | T | A | 0.0000 | |
| 284 | R | A | -0.4160 | |
| 285 | I | A | 0.0000 | |
| 286 | V | A | 0.0000 | |
| 287 | L | A | 0.0000 | |
| 288 | V | A | 0.3047 | |
| 289 | A | A | 0.0000 | |
| 290 | M | A | 0.1033 | |
| 291 | E | A | -0.4368 | |
| 292 | T | A | -0.0973 | |
| 293 | W | A | 0.0000 | |
| 294 | A | A | 0.0130 | |
| 295 | T | A | -0.2243 | |
| 296 | D | A | -0.9172 | |
| 297 | N | A | -0.4708 | |
| 298 | K | A | -0.6396 | |
| 299 | F | A | 0.0000 | |
| 300 | A | A | 0.1202 | |
| 301 | I | A | 0.3429 | |
| 302 | S | A | -0.2980 | |
| 303 | E | A | -1.8888 | |
| 304 | N | A | -0.6834 | |
| 305 | P | A | 0.0000 | |
| 306 | L | A | 0.4158 | |
| 307 | I | A | 1.1613 | |
| 308 | T | A | 0.0000 | |
| 309 | L | A | 0.0000 | |
| 310 | R | A | -0.7771 | |
| 311 | E | A | -0.8672 | |
| 312 | F | A | 0.0000 | |
| 313 | M | A | 0.0000 | |
| 314 | K | A | -0.4670 | |
| 315 | Y | A | 0.0000 | |
| 316 | R | A | -0.3053 | |
| 317 | R | A | -0.6717 | |
| 318 | D | A | 0.0000 | |
| 319 | F | A | 0.3820 | |
| 320 | I | A | 0.0000 | |
| 321 | K | A | -2.0321 | |
| 322 | E | A | -2.4404 | |
| 323 | K | A | -2.0380 | |
| 324 | S | A | -0.3443 | |
| 325 | D | A | 0.0000 | |
| 326 | A | A | 0.0000 | |
| 327 | V | A | 0.0000 | |
| 328 | H | A | 0.0000 | |
| 329 | L | A | 0.0000 | |
| 330 | F | A | 0.0000 | |
| 331 | S | A | 0.0000 | |
| 332 | G | A | 0.0000 | |
| 333 | S | A | -0.2772 | |
| 334 | Q | A | -1.2090 | |
| 335 | F | A | 0.0000 | |
| 336 | E | A | -1.8541 | |
| 337 | S | A | -0.5590 | |
| 338 | S | A | -0.5847 | |
| 339 | R | A | -1.8831 | |
| 340 | S | A | 0.0000 | |
| 341 | G | A | -0.0853 | |
| 342 | A | A | 0.0000 | |
| 343 | A | A | 0.0058 | |
| 344 | Y | A | 0.0000 | |
| 345 | I | A | 0.4677 | |
| 346 | G | A | -0.0783 | |
| 347 | G | A | 0.0000 | |
| 348 | I | A | 0.0000 | |
| 349 | C | A | 0.3916 | |
| 350 | S | A | 0.2592 | |
| 351 | L | A | 1.5474 | |
| 352 | L | A | 0.7232 | |
| 353 | K | A | -1.0392 | |
| 354 | G | A | 0.0000 | |
| 355 | G | A | 0.0000 | |
| 356 | G | A | 0.0000 | |
| 357 | V | A | 0.0000 | |
| 358 | N | A | 0.0000 | |
| 359 | E | A | -0.1613 | |
| 360 | F | A | 0.3108 | |
| 361 | G | A | -0.3587 | |
| 362 | K | A | -1.7025 | |
| 363 | T | A | -0.4832 | |
| 364 | D | A | -0.7075 | |
| 365 | L | A | -0.0638 | |
| 366 | M | A | 0.0000 | |
| 367 | A | A | 0.0000 | |
| 368 | V | A | 0.0000 | |
| 369 | T | A | 0.0000 | |
| 370 | L | A | 0.0000 | |
| 371 | A | A | 0.0000 | |
| 372 | Q | A | -0.1818 | |
| 373 | S | A | 0.0000 | |
| 374 | L | A | 0.0000 | |
| 375 | A | A | 0.0000 | |
| 376 | H | A | -0.1537 | |
| 377 | N | A | 0.0000 | |
| 378 | I | A | 0.0000 | |
| 379 | G | A | -0.0711 | |
| 380 | I | A | 0.0000 | |
| 381 | I | A | 0.0000 | |
| 382 | S | A | -0.0344 | |
| 383 | D | A | 0.0000 | |
| 384 | K | A | -1.3754 | |
| 385 | R | A | -1.0352 | |
| 386 | K | A | -0.8719 | |
| 387 | L | A | 0.4843 | |
| 388 | A | A | 0.1559 | |
| 389 | S | A | -0.2230 | |
| 390 | G | A | -0.4112 | |
| 391 | E | A | -1.9176 | |
| 392 | C | A | 0.0000 | |
| 393 | K | A | -1.4595 | |
| 394 | Y | A | 0.6724 | mutated: CA394Y |
| 395 | E | A | -1.8594 | |
| 396 | D | A | -1.8634 | |
| 397 | T | A | -0.1443 | |
| 398 | W | A | 1.1625 | |
| 399 | S | A | 0.1419 | |
| 400 | G | A | -0.1038 | |
| 401 | C | A | 0.0000 | |
| 402 | I | A | 0.0000 | |
| 403 | M | A | 0.0000 | |
| 404 | G | A | -0.4056 | |
| 405 | D | A | -1.8166 | |
| 406 | T | A | -0.4811 | |
| 407 | G | A | -0.3253 | |
| 408 | Y | A | 0.9910 | |
| 409 | Y | A | 1.5349 | |
| 410 | L | A | 0.6041 | |
| 411 | P | A | 0.0000 | |
| 412 | K | A | -0.8682 | |
| 413 | K | A | -0.8226 | |
| 414 | F | A | 0.0000 | |
| 415 | T | A | -0.1749 | |
| 416 | Q | A | -0.8970 | |
| 417 | C | A | -0.0665 | |
| 418 | N | A | 0.0000 | |
| 419 | I | A | -0.0342 | |
| 420 | E | A | -1.8257 | |
| 421 | E | A | -0.5278 | |
| 422 | Y | A | 0.0000 | |
| 423 | H | A | -0.7495 | |
| 424 | D | A | -1.8937 | |
| 425 | F | A | 0.0000 | |
| 426 | L | A | 0.0000 | |
| 427 | N | A | -0.7928 | |
| 428 | S | A | -0.1478 | |
| 429 | G | A | -0.0520 | |
| 430 | G | A | 0.0000 | |
| 431 | G | A | 0.0000 | |
| 432 | A | A | 0.0359 | |
| 433 | C | A | 0.1643 | |
| 434 | L | A | 0.0000 | |
| 435 | F | A | 0.0000 | |
| 436 | N | A | -0.4470 | |
| 437 | K | A | -0.5088 | |
| 438 | P | A | -0.1256 | |
| 439 | S | A | -0.4249 | |
| 440 | K | A | -1.6600 | |
| 441 | L | A | 0.1710 | |
| 442 | L | A | 0.7687 | |
| 443 | D | A | -0.9510 | |
| 444 | P | A | -0.4776 | |
| 445 | P | A | -0.5512 | |
| 446 | E | A | -1.7245 | |
| 447 | C | A | 0.3292 | |
| 448 | G | A | -0.1483 | |
| 449 | N | A | -0.7219 | |
| 450 | G | A | -0.2200 | |
| 451 | F | A | 0.0000 | |
| 452 | I | A | 0.9961 | |
| 453 | E | A | 0.0000 | |
| 454 | T | A | -0.1567 | |
| 455 | G | A | -0.5778 | |
| 456 | E | A | -0.9544 | |
| 457 | E | A | -1.9180 | |
| 458 | C | A | 0.0000 | |
| 459 | D | A | 0.0000 | |
| 460 | C | A | 0.0519 | |
| 461 | G | A | -0.1692 | |
| 462 | T | A | -0.1039 | |
| 463 | P | A | -0.2492 | |
| 464 | A | A | -0.3177 | |
| 465 | E | A | -1.8093 | |
| 466 | C | A | 0.0000 | |
| 467 | V | A | 2.0552 | |
| 468 | L | A | 1.6217 | |
| 469 | E | A | -1.0838 | |
| 470 | G | A | 0.0000 | |
| 471 | A | A | -0.3248 | |
| 472 | E | A | -1.8180 | |
| 473 | C | A | 0.0000 | |
| 474 | C | A | 0.0000 | |
| 475 | K | A | -1.7113 | |
| 476 | K | A | -1.9552 | |
| 477 | C | A | 0.0000 | |
| 478 | T | A | 0.0096 | |
| 479 | L | A | 0.2802 | |
| 480 | T | A | -0.2016 | |
| 481 | Q | A | -1.5321 | |
| 482 | D | A | -2.0150 | |
| 483 | S | A | -0.5749 | |
| 484 | Q | A | -1.1441 | |
| 485 | C | A | 0.0000 | |
| 486 | S | A | 0.0000 | |
| 487 | D | A | -0.4399 | |
| 488 | G | A | 0.0139 | |
| 489 | L | A | 1.1165 | |
| 490 | C | A | 0.0000 | |
| 491 | C | A | 0.0000 | |
| 492 | K | A | -2.0102 | |
| 493 | K | A | -1.9941 | |
| 494 | C | A | -0.4220 | |
| 495 | K | A | -1.0095 | |
| 496 | F | A | 0.0625 | |
| 497 | Q | A | -0.2011 | |
| 498 | P | A | -0.1141 | |
| 499 | M | A | 0.9250 | |
| 500 | G | A | -0.0926 | |
| 501 | T | A | 0.0892 | |
| 502 | V | A | 0.8862 | |
| 503 | C | A | 0.2663 | |
| 504 | R | A | 0.0000 | |
| 505 | E | A | -2.0362 | |
| 506 | A | A | -0.4522 | |
| 507 | V | A | 0.4078 | |
| 508 | N | A | -0.5271 | |
| 509 | D | A | -1.8412 | |
| 510 | C | A | 0.0000 | |
| 511 | D | A | -0.1361 | |
| 512 | I | A | -0.1507 | |
| 513 | R | A | -2.0198 | |
| 514 | E | A | 0.0000 | |
| 515 | T | A | 0.0633 | |
| 516 | C | A | 0.0000 | |
| 517 | S | A | 0.0157 | |
| 518 | G | A | -0.2223 | |
| 519 | N | A | -1.3132 | |
| 520 | S | A | -0.3376 | |
| 521 | S | A | -0.1573 | |
| 522 | Q | A | -0.5367 | |
| 523 | C | A | 0.0000 | |
| 524 | A | A | -0.0308 | |
| 525 | P | A | -0.2771 | |
| 526 | N | A | -0.1432 | |
| 527 | I | A | 0.1870 | |
| 528 | H | A | 0.0000 | |
| 529 | K | A | -0.2641 | |
| 530 | M | A | -0.1742 | |
| 531 | D | A | -0.7740 | |
| 532 | G | A | -0.2803 | |
| 533 | Y | A | 0.1637 | |
| 534 | S | A | -0.0798 | |
| 535 | C | A | 0.0000 | |
| 536 | D | A | -1.8746 | |
| 537 | G | A | -0.4722 | |
| 538 | V | A | 1.4705 | |
| 539 | Q | A | -0.8760 | |
| 540 | G | A | 0.0000 | |
| 541 | I | A | 0.1773 | |
| 542 | C | A | 0.0000 | |
| 543 | F | A | 0.1120 | |
| 544 | G | A | -0.4140 | |
| 545 | G | A | 0.0000 | |
| 546 | R | A | -0.7211 | |
| 547 | C | A | -0.0723 | |
| 548 | K | A | -0.4322 | |
| 549 | T | A | 0.0000 | |
| 550 | R | A | -0.3138 | |
| 551 | D | A | -0.8513 | |
| 552 | R | A | -1.5809 | |
| 553 | Q | A | 0.0000 | |
| 554 | C | A | 0.0000 | |
| 555 | K | A | -0.2923 | |
| 556 | Y | A | 0.3997 | |
| 557 | I | A | 0.0000 | |
| 558 | W | A | 0.0000 | |
| 559 | G | A | 0.0000 | |
| 560 | Q | A | -1.5349 | |
| 561 | K | A | -1.9188 | |
| 562 | V | A | 0.0000 | |
| 563 | T | A | -0.0395 | |
| 564 | A | A | -0.0676 | |
| 565 | S | A | 0.0000 | |
| 566 | D | A | -1.7931 | |
| 567 | K | A | -1.9219 | |
| 568 | Y | A | -0.1794 | |
| 569 | C | A | 0.0000 | |
| 570 | Y | A | 0.0000 | |
| 571 | E | A | -1.3632 | |
| 572 | K | A | -1.3439 | |
| 573 | L | A | 0.0000 | |
| 574 | N | A | 0.0000 | |
| 575 | I | A | -0.0911 | |
| 576 | E | A | -1.7702 | |
| 577 | G | A | -0.6529 | |
| 578 | T | A | -0.3671 | |
| 579 | E | A | -1.9322 | |
| 580 | K | A | -0.9298 | |
| 581 | G | A | 0.0000 | |
| 582 | N | A | 0.0000 | |
| 583 | C | A | 0.0000 | |
| 584 | G | A | 0.0000 | |
| 585 | K | A | -1.9902 | |
| 586 | D | A | -2.4099 | |
| 587 | K | A | -2.3527 | |
| 588 | D | A | -2.1132 | |
| 589 | T | A | -0.3479 | |
| 590 | W | A | 0.1280 | |
| 591 | I | A | 0.4517 | |
| 592 | Q | A | -1.0622 | |
| 593 | C | A | 0.0000 | |
| 594 | N | A | -0.5776 | |
| 595 | K | A | -1.8196 | |
| 596 | R | A | -0.6983 | |
| 597 | D | A | 0.0000 | |
| 598 | V | A | 0.0000 | |
| 599 | L | A | 0.0000 | |
| 600 | C | A | 0.0000 | |
| 601 | G | A | 0.0000 | |
| 602 | Y | A | 0.0000 | |
| 603 | L | A | 0.0000 | |
| 604 | L | A | 0.0000 | |
| 605 | C | A | 0.0000 | |
| 606 | T | A | -0.2449 | |
| 607 | N | A | -1.2228 | |
| 608 | I | A | 0.0155 | |
| 609 | G | A | -0.3564 | |
| 610 | N | A | -1.2196 | |
| 611 | I | A | 0.2317 | |
| 612 | P | A | 0.0000 | |
| 613 | R | A | -0.4522 | |
| 614 | L | A | 0.0000 | |
| 615 | G | A | -0.6049 | |
| 616 | E | A | -1.9201 | |
| 617 | L | A | -0.4201 | |
| 618 | D | A | -1.8304 | |
| 619 | G | A | -1.1328 | |
| 620 | E | A | -1.8124 | |
| 621 | I | A | 0.1693 | |
| 622 | T | A | 0.0000 | |
| 623 | S | A | -0.2149 | |
| 624 | T | A | 0.2329 | |
| 625 | L | A | 1.5779 | |
| 626 | V | A | 0.7854 | |
| 627 | V | A | 1.7609 | |
| 628 | Q | A | -0.2781 | |
| 629 | Q | A | -1.3172 | |
| 630 | G | A | -1.0235 | |
| 631 | R | A | -1.9629 | |
| 632 | T | A | -0.1107 | |
| 633 | L | A | 0.1214 | |
| 634 | N | A | -0.6578 | |
| 635 | C | A | 0.0000 | |
| 636 | S | A | 0.0000 | |
| 637 | G | A | 0.0000 | |
| 638 | G | A | 0.0000 | |
| 639 | H | A | -0.1448 | |
| 640 | V | A | 0.0000 | |
| 641 | K | A | -0.9031 | |
| 642 | L | A | 0.4735 | |
| 643 | E | A | -0.3144 | |
| 644 | E | A | -2.1796 | |
| 645 | D | A | -2.0079 | |
| 646 | V | A | 0.1752 | |
| 647 | D | A | -0.5371 | |
| 648 | L | A | 0.0000 | |
| 649 | G | A | 0.0000 | |
| 650 | Y | A | 0.0000 | |
| 651 | V | A | 0.0000 | |
| 652 | E | A | -0.9113 | |
| 653 | D | A | -0.9035 | |
| 654 | G | A | 0.0000 | |
| 655 | T | A | 0.0000 | |
| 656 | P | A | 0.0000 | |
| 657 | C | A | 0.0371 | |
| 658 | G | A | -0.2479 | |
| 659 | P | A | -0.5110 | |
| 660 | Q | A | -1.2080 | |
| 661 | M | A | -0.0272 | |
| 662 | M | A | 0.0000 | |
| 663 | C | A | 0.0000 | |
| 664 | L | A | -0.1200 | |
| 665 | E | A | -1.8063 | |
| 666 | H | A | -0.6146 | |
| 667 | R | A | -0.3474 | |
| 668 | C | A | 0.0000 | |
| 669 | L | A | 0.0000 | |
| 670 | P | A | 0.0822 | |
| 671 | V | A | 0.5350 | |
| 672 | A | A | 0.1474 | |
| 673 | S | A | 0.0279 | |
| 674 | F | A | 0.0945 | |
| 675 | N | A | -1.0925 | |
| 676 | F | A | 0.3806 | |
| 677 | S | A | -0.1057 | |
| 678 | T | A | -0.1097 | |
| 679 | C | A | 0.0000 | |
| 680 | L | A | 1.5116 | |
| 681 | S | A | 0.1893 | |
| 682 | S | A | -0.3362 | |
| 683 | K | A | -1.4741 | |
| 684 | E | A | -2.1098 | |
| 685 | G | A | -0.8061 | |
| 686 | T | A | 0.0422 | |
| 687 | I | A | 0.8640 | |
| 688 | C | A | 0.0000 | |
| 689 | S | A | 0.0000 | |
| 690 | G | A | -0.5019 | |
| 691 | N | A | -0.2938 | |
| 692 | G | A | -0.0086 | |
| 693 | V | A | 0.3914 | |
| 694 | C | A | 0.0000 | |
| 695 | S | A | 0.0000 | |
| 696 | N | A | -0.8647 | |
| 697 | E | A | -1.6559 | |
| 698 | L | A | 0.0679 | |
| 699 | K | A | -1.5570 | |
| 700 | C | A | -0.0820 | |
| 701 | V | A | 0.7904 | |
| 702 | C | A | 0.0724 | |
| 703 | N | A | -1.5757 | |
| 704 | R | A | -2.1297 | |
| 705 | H | A | -0.5984 | |
| 706 | W | A | 0.5811 | |
| 707 | I | A | 1.0035 | |
| 708 | G | A | -0.3040 | |
| 709 | S | A | -0.3359 | |
| 710 | D | A | -0.0924 | |
| 711 | C | A | 0.0000 | |
| 712 | N | A | -0.4847 | |
| 713 | T | A | 0.1040 | |
| 714 | Y | A | 1.6057 | |
| 715 | F | A | 1.6594 | |
| 716 | P | A | -0.1336 | |
| 717 | H | A | -1.2517 | |
| 718 | N | A | -1.4519 | |
| 233 | N | B | -1.2730 | |
| 234 | V | B | 0.0000 | |
| 235 | E | B | -0.8982 | |
| 236 | E | B | -1.9585 | |
| 237 | E | B | -0.5313 | |
| 238 | T | B | -0.0642 | |
| 239 | K | B | 0.0000 | |
| 240 | Y | B | 0.0925 | |
| 241 | I | B | 0.0000 | |
| 242 | E | B | -0.2436 | |
| 243 | L | B | 0.0000 | |
| 244 | M | B | 0.0000 | |
| 245 | I | B | 0.0000 | |
| 246 | V | B | 0.0000 | |
| 247 | N | B | 0.0000 | |
| 248 | D | B | 0.0000 | |
| 249 | H | B | 0.0218 | |
| 250 | L | B | 0.5718 | |
| 251 | M | B | 0.0000 | |
| 252 | F | B | 0.0000 | |
| 253 | K | B | -1.5726 | |
| 254 | K | B | -1.6894 | |
| 255 | H | B | -0.7031 | |
| 256 | R | B | -1.5823 | |
| 257 | L | B | 1.2058 | |
| 258 | S | B | 0.5229 | |
| 259 | V | B | 1.8249 | |
| 260 | V | B | 1.9413 | |
| 261 | H | B | -0.2620 | |
| 262 | T | B | 0.0000 | |
| 263 | N | B | -0.2635 | |
| 264 | T | B | -0.1020 | |
| 265 | Y | B | 0.2252 | |
| 266 | A | B | 0.0000 | |
| 267 | K | B | -0.3015 | |
| 268 | S | B | -0.2410 | |
| 269 | V | B | 0.0000 | |
| 270 | V | B | 0.0000 | |
| 271 | N | B | -1.1544 | |
| 272 | M | B | 0.1766 | |
| 273 | A | B | 0.0000 | |
| 274 | D | B | 0.0000 | |
| 275 | L | B | 1.3275 | |
| 276 | I | B | 0.4740 | |
| 277 | Y | B | 0.0000 | |
| 278 | K | B | -1.3215 | |
| 279 | D | B | -2.0517 | |
| 280 | Q | B | -0.6181 | |
| 281 | L | B | 0.0000 | |
| 282 | K | B | -1.2566 | |
| 283 | T | B | 0.0000 | |
| 284 | R | B | -0.3337 | |
| 285 | I | B | 0.0000 | |
| 286 | V | B | 0.0000 | |
| 287 | L | B | 0.0000 | |
| 288 | V | B | 0.2984 | |
| 289 | A | B | 0.0000 | |
| 290 | M | B | 0.0781 | |
| 291 | E | B | -0.4344 | |
| 292 | T | B | -0.0958 | |
| 293 | W | B | 0.0000 | |
| 294 | A | B | 0.0157 | |
| 295 | T | B | -0.3919 | |
| 296 | D | B | -1.8500 | |
| 297 | N | B | -0.7032 | |
| 298 | K | B | -0.6760 | |
| 299 | F | B | 0.0000 | |
| 300 | A | B | 0.1276 | |
| 301 | I | B | 0.3835 | |
| 302 | S | B | -0.2920 | |
| 303 | E | B | -1.8888 | |
| 304 | N | B | -0.6817 | |
| 305 | P | B | 0.0000 | |
| 306 | L | B | 0.3203 | |
| 307 | I | B | 0.6303 | |
| 308 | T | B | 0.0000 | |
| 309 | L | B | 0.0000 | |
| 310 | R | B | -1.8891 | |
| 311 | E | B | -0.5830 | |
| 312 | F | B | 0.0000 | |
| 313 | M | B | 0.0000 | |
| 314 | K | B | -0.5129 | |
| 315 | Y | B | 0.0000 | |
| 316 | R | B | -0.3315 | |
| 317 | R | B | -0.8035 | |
| 318 | D | B | 0.0000 | |
| 319 | F | B | 0.3761 | |
| 320 | I | B | 0.0000 | |
| 321 | K | B | -2.0161 | |
| 322 | E | B | -2.3488 | |
| 323 | K | B | -2.0214 | |
| 324 | S | B | -0.3459 | |
| 325 | D | B | 0.0000 | |
| 326 | A | B | 0.0000 | |
| 327 | V | B | 0.0000 | |
| 328 | H | B | 0.0000 | |
| 329 | L | B | 0.0000 | |
| 330 | F | B | 0.0000 | |
| 331 | S | B | 0.0000 | |
| 332 | G | B | 0.0000 | |
| 333 | S | B | -0.2955 | |
| 334 | Q | B | -1.2123 | |
| 335 | F | B | 0.0000 | |
| 336 | E | B | -1.8548 | |
| 337 | S | B | -0.5629 | |
| 338 | S | B | -0.5855 | |
| 339 | R | B | -1.8885 | |
| 340 | S | B | -0.3817 | |
| 341 | G | B | -0.0773 | |
| 342 | A | B | 0.0000 | |
| 343 | A | B | 0.0302 | |
| 344 | Y | B | 0.2247 | |
| 345 | I | B | 0.4653 | |
| 346 | G | B | -0.0720 | |
| 347 | G | B | 0.0000 | |
| 348 | I | B | 0.0000 | |
| 349 | C | B | 0.3935 | |
| 350 | S | B | 0.2660 | |
| 351 | L | B | 1.7328 | |
| 352 | L | B | 1.2252 | |
| 353 | K | B | -0.9160 | |
| 354 | G | B | 0.0000 | |
| 355 | G | B | 0.0000 | |
| 356 | G | B | 0.0000 | |
| 357 | V | B | 0.0000 | |
| 358 | N | B | 0.0000 | |
| 359 | E | B | -0.1324 | |
| 360 | F | B | 0.2777 | |
| 361 | G | B | -0.3627 | |
| 362 | K | B | -1.7033 | |
| 363 | T | B | -0.4789 | |
| 364 | D | B | -0.7993 | |
| 365 | L | B | -0.1303 | |
| 366 | M | B | 0.0000 | |
| 367 | A | B | 0.0000 | |
| 368 | V | B | 0.0000 | |
| 369 | T | B | 0.0000 | |
| 370 | L | B | 0.0000 | |
| 371 | A | B | 0.0000 | |
| 372 | Q | B | -0.2298 | |
| 373 | S | B | 0.0000 | |
| 374 | L | B | 0.0000 | |
| 375 | A | B | 0.0000 | |
| 376 | H | B | -0.1359 | |
| 377 | N | B | 0.0000 | |
| 378 | I | B | 0.0000 | |
| 379 | G | B | -0.0706 | |
| 380 | I | B | 0.0000 | |
| 381 | I | B | 0.0000 | |
| 382 | S | B | -0.0347 | |
| 383 | D | B | 0.0000 | |
| 384 | K | B | -1.2980 | |
| 385 | R | B | -1.1302 | |
| 386 | K | B | -1.1257 | |
| 387 | L | B | 0.2229 | |
| 388 | A | B | 0.1167 | |
| 389 | S | B | -0.2641 | |
| 390 | G | B | -0.6564 | |
| 391 | E | B | -1.9813 | |
| 392 | C | B | 0.0000 | |
| 393 | K | B | -1.6659 | |
| 394 | C | B | -0.4556 | |
| 395 | E | B | -2.1158 | |
| 396 | D | B | -2.1380 | |
| 397 | T | B | -0.1996 | |
| 398 | W | B | 1.1433 | |
| 399 | S | B | 0.0327 | |
| 400 | G | B | -0.1583 | |
| 401 | C | B | 0.0000 | |
| 402 | I | B | 0.0000 | |
| 403 | M | B | 0.0000 | |
| 404 | G | B | -0.4846 | |
| 405 | D | B | -1.8310 | |
| 406 | T | B | -0.4498 | |
| 407 | G | B | -0.0688 | |
| 408 | Y | B | 1.5016 | |
| 409 | Y | B | 1.6097 | |
| 410 | L | B | 0.5313 | |
| 411 | P | B | 0.0000 | |
| 412 | K | B | -0.6831 | |
| 413 | K | B | -0.8028 | |
| 414 | F | B | 0.0000 | |
| 415 | T | B | -0.2138 | |
| 416 | Q | B | -1.0921 | |
| 417 | C | B | -0.0433 | |
| 418 | N | B | 0.0000 | |
| 419 | I | B | -0.0153 | |
| 420 | E | B | -1.8215 | |
| 421 | E | B | -0.5305 | |
| 422 | Y | B | 0.0000 | |
| 423 | H | B | -0.7382 | |
| 424 | D | B | -1.8555 | |
| 425 | F | B | -0.1444 | |
| 426 | L | B | 0.0000 | |
| 427 | N | B | -0.7742 | |
| 428 | S | B | -0.1351 | |
| 429 | G | B | -0.0556 | |
| 430 | G | B | 0.0000 | |
| 431 | G | B | 0.0000 | |
| 432 | A | B | 0.0374 | |
| 433 | C | B | 0.1687 | |
| 434 | L | B | 0.0000 | |
| 435 | F | B | 0.0000 | |
| 436 | N | B | -0.4936 | |
| 437 | K | B | -0.5065 | |
| 438 | P | B | -0.1204 | |
| 439 | S | B | -0.4088 | |
| 440 | K | B | -1.6590 | |
| 441 | L | B | 0.1562 | |
| 442 | L | B | 0.7250 | |
| 443 | D | B | -1.0383 | |
| 444 | P | B | -0.4917 | |
| 445 | P | B | -0.5515 | |
| 446 | E | B | -1.7277 | |
| 447 | C | B | 0.3135 | |
| 448 | G | B | -0.0964 | |
| 449 | N | B | -0.4877 | |
| 450 | G | B | -0.1730 | |
| 451 | F | B | 0.0000 | |
| 452 | I | B | 1.0065 | |
| 453 | E | B | 0.0000 | |
| 454 | T | B | -0.1566 | |
| 455 | G | B | -0.5477 | |
| 456 | E | B | -0.7712 | |
| 457 | E | B | -1.7778 | |
| 458 | C | B | 0.0000 | |
| 459 | D | B | 0.0000 | |
| 460 | C | B | 0.0444 | |
| 461 | G | B | -0.2158 | |
| 462 | T | B | -0.1278 | |
| 463 | P | B | -0.2520 | |
| 464 | A | B | -0.3179 | |
| 465 | E | B | -1.8093 | |
| 466 | C | B | 0.0000 | |
| 467 | V | B | 2.0553 | |
| 468 | L | B | 1.6167 | |
| 469 | E | B | -1.1128 | |
| 470 | G | B | 0.0000 | |
| 471 | A | B | -0.3248 | |
| 472 | E | B | -1.8181 | |
| 473 | C | B | 0.0000 | |
| 474 | C | B | 0.0000 | |
| 475 | K | B | -1.7486 | |
| 476 | K | B | -1.9621 | |
| 477 | C | B | 0.0000 | |
| 478 | T | B | 0.0176 | |
| 479 | L | B | 0.3266 | |
| 480 | T | B | -0.1922 | |
| 481 | Q | B | -1.5319 | |
| 482 | D | B | -2.0144 | |
| 483 | S | B | -0.5405 | |
| 484 | Q | B | -0.9739 | |
| 485 | C | B | 0.0000 | |
| 486 | S | B | 0.0000 | |
| 487 | D | B | -0.4569 | |
| 488 | G | B | 0.0055 | |
| 489 | L | B | 1.0651 | |
| 490 | C | B | 0.0000 | |
| 491 | C | B | 0.0000 | |
| 492 | K | B | -2.0098 | |
| 493 | K | B | -1.9936 | |
| 494 | C | B | -0.4260 | |
| 495 | K | B | -1.0415 | |
| 496 | F | B | 0.0367 | |
| 497 | Q | B | -0.2089 | |
| 498 | P | B | -0.1150 | |
| 499 | M | B | 0.9557 | |
| 500 | G | B | 0.0783 | |
| 501 | T | B | 0.1106 | |
| 502 | V | B | 0.8330 | |
| 503 | C | B | 0.2565 | |
| 504 | R | B | 0.0000 | |
| 505 | E | B | -2.0345 | |
| 506 | A | B | -0.4497 | |
| 507 | V | B | 0.3832 | |
| 508 | N | B | -0.5209 | |
| 509 | D | B | -1.8213 | |
| 510 | C | B | 0.0000 | |
| 511 | D | B | -0.1464 | |
| 512 | I | B | -0.1616 | |
| 513 | R | B | -2.0202 | |
| 514 | E | B | 0.0000 | |
| 515 | T | B | 0.0737 | |
| 516 | C | B | 0.0000 | |
| 517 | S | B | 0.0123 | |
| 518 | G | B | -0.2205 | |
| 519 | N | B | -1.3125 | |
| 520 | S | B | -0.3325 | |
| 521 | S | B | -0.1571 | |
| 522 | Q | B | -0.5503 | |
| 523 | C | B | 0.0000 | |
| 524 | A | B | -0.0305 | |
| 525 | P | B | -0.2766 | |
| 526 | N | B | -0.1795 | |
| 527 | I | B | 0.0000 | |
| 528 | H | B | 0.0000 | |
| 529 | K | B | -0.2899 | |
| 530 | M | B | -0.1502 | |
| 531 | D | B | -0.5789 | |
| 532 | G | B | -0.2628 | |
| 533 | Y | B | 0.1921 | |
| 534 | S | B | -0.0699 | |
| 535 | C | B | 0.0000 | |
| 536 | D | B | -1.8107 | |
| 537 | G | B | -0.4608 | |
| 538 | V | B | 1.4706 | |
| 539 | Q | B | -0.8764 | |
| 540 | G | B | 0.0000 | |
| 541 | I | B | 0.1755 | |
| 542 | C | B | 0.0000 | |
| 543 | F | B | 0.1622 | |
| 544 | G | B | -0.4089 | |
| 545 | G | B | 0.0000 | |
| 546 | R | B | -0.8553 | |
| 547 | C | B | -0.1098 | |
| 548 | K | B | -0.4255 | |
| 549 | T | B | 0.0000 | |
| 550 | R | B | -0.3262 | |
| 551 | D | B | -0.9809 | |
| 552 | R | B | -1.9549 | |
| 553 | Q | B | 0.0000 | |
| 554 | C | B | 0.0000 | |
| 555 | K | B | -0.2940 | |
| 556 | Y | B | 0.4919 | |
| 557 | I | B | 0.0000 | |
| 558 | W | B | 0.0000 | |
| 559 | G | B | -0.3006 | |
| 560 | Q | B | -1.5449 | |
| 561 | K | B | -1.9189 | |
| 562 | V | B | 0.0000 | |
| 563 | T | B | -0.0393 | |
| 564 | A | B | -0.0763 | |
| 565 | S | B | 0.0000 | |
| 566 | D | B | -1.7628 | |
| 567 | K | B | -1.9161 | |
| 568 | Y | B | -0.2477 | |
| 569 | C | B | 0.0000 | |
| 570 | Y | B | 0.0000 | |
| 571 | E | B | -2.0362 | |
| 572 | K | B | -1.6787 | |
| 573 | L | B | 0.0000 | |
| 574 | N | B | 0.0000 | |
| 575 | I | B | 0.0011 | |
| 576 | E | B | -1.7532 | |
| 577 | G | B | -0.6532 | |
| 578 | T | B | -0.3677 | |
| 579 | E | B | -1.9626 | |
| 580 | K | B | -1.0953 | |
| 581 | G | B | 0.0000 | |
| 582 | N | B | 0.0000 | |
| 583 | C | B | 0.0771 | |
| 584 | G | B | 0.0000 | |
| 585 | K | B | -1.9913 | |
| 586 | D | B | -2.4103 | |
| 587 | K | B | -2.3529 | |
| 588 | D | B | -2.1129 | |
| 589 | T | B | -0.3498 | |
| 590 | W | B | 0.1324 | |
| 591 | I | B | 0.5289 | |
| 592 | Q | B | -1.0369 | |
| 593 | C | B | 0.0000 | |
| 594 | N | B | -0.6279 | |
| 595 | K | B | -1.8438 | |
| 596 | R | B | -0.7809 | |
| 597 | D | B | 0.0000 | |
| 598 | V | B | 0.0000 | |
| 599 | L | B | 0.1547 | |
| 600 | C | B | 0.0000 | |
| 601 | G | B | 0.0000 | |
| 602 | Y | B | 0.0000 | |
| 603 | L | B | 0.0000 | |
| 604 | L | B | 0.0000 | |
| 605 | C | B | 0.0000 | |
| 606 | T | B | -0.2447 | |
| 607 | N | B | -1.2239 | |
| 608 | I | B | 0.0270 | |
| 609 | G | B | -0.2654 | |
| 610 | N | B | -1.2087 | |
| 611 | I | B | 0.1992 | |
| 612 | P | B | 0.0000 | |
| 613 | R | B | -0.4641 | |
| 614 | L | B | 0.0000 | |
| 615 | G | B | -0.6208 | |
| 616 | E | B | -1.9213 | |
| 617 | L | B | -0.4231 | |
| 618 | D | B | -1.8307 | |
| 619 | G | B | -1.1324 | |
| 620 | E | B | -1.8028 | |
| 621 | I | B | 0.2212 | |
| 622 | T | B | 0.0571 | |
| 623 | S | B | -0.2163 | |
| 624 | T | B | 0.2327 | |
| 625 | L | B | 1.5455 | |
| 626 | V | B | 0.0000 | |
| 627 | V | B | 1.7000 | |
| 628 | Q | B | -0.4309 | |
| 629 | Q | B | -1.3454 | |
| 630 | G | B | -1.0243 | |
| 631 | R | B | -1.9795 | |
| 632 | T | B | -0.1090 | |
| 633 | L | B | 0.1436 | |
| 634 | N | B | -0.5894 | |
| 635 | C | B | 0.0000 | |
| 636 | S | B | 0.0000 | |
| 637 | G | B | 0.0000 | |
| 638 | G | B | 0.0000 | |
| 639 | H | B | -0.1346 | |
| 640 | V | B | 0.0000 | |
| 641 | K | B | -0.9135 | |
| 642 | L | B | 0.2999 | |
| 643 | E | B | -0.5957 | |
| 644 | E | B | -2.2284 | |
| 645 | D | B | -1.9908 | |
| 646 | V | B | 0.2619 | |
| 647 | D | B | -0.4046 | |
| 648 | L | B | 0.0000 | |
| 649 | G | B | 0.0000 | |
| 650 | Y | B | 0.1288 | |
| 651 | V | B | 0.0000 | |
| 652 | E | B | -1.0296 | |
| 653 | D | B | -0.8422 | |
| 654 | G | B | 0.0000 | |
| 655 | T | B | 0.0000 | |
| 656 | P | B | 0.0000 | |
| 657 | C | B | 0.0438 | |
| 658 | G | B | -0.2371 | |
| 659 | P | B | -0.5094 | |
| 660 | Q | B | -1.2054 | |
| 661 | M | B | -0.0111 | |
| 662 | M | B | 0.0000 | |
| 663 | C | B | 0.0000 | |
| 664 | L | B | -0.1465 | |
| 665 | E | B | -1.8192 | |
| 666 | H | B | -0.6375 | |
| 667 | R | B | -0.2960 | |
| 668 | C | B | 0.0000 | |
| 669 | L | B | 0.0000 | |
| 670 | P | B | 0.0842 | |
| 671 | V | B | 0.5297 | |
| 672 | A | B | 0.1489 | |
| 673 | S | B | 0.0394 | |
| 674 | F | B | 0.0903 | |
| 675 | N | B | -1.1090 | |
| 676 | F | B | 0.2978 | |
| 677 | S | B | -0.1210 | |
| 678 | T | B | -0.0967 | |
| 679 | C | B | 0.3386 | |
| 680 | L | B | 1.5045 | |
| 681 | S | B | 0.1417 | |
| 682 | S | B | -0.4929 | |
| 683 | K | B | -2.0618 | |
| 684 | E | B | -2.2160 | |
| 685 | G | B | -0.8058 | |
| 686 | T | B | 0.1878 | |
| 687 | I | B | 1.6371 | |
| 688 | C | B | 0.0000 | |
| 689 | S | B | 0.0000 | |
| 690 | G | B | -0.5108 | |
| 691 | N | B | -0.3464 | |
| 692 | G | B | -0.0353 | |
| 693 | V | B | 0.4070 | |
| 694 | C | B | 0.0000 | |
| 695 | S | B | 0.0000 | |
| 696 | N | B | -0.8952 | |
| 697 | E | B | -1.7983 | |
| 698 | L | B | 0.1317 | |
| 699 | K | B | -1.1868 | |
| 700 | C | B | -0.0839 | |
| 701 | V | B | 0.4900 | |
| 702 | C | B | 0.0153 | |
| 703 | N | B | -1.5757 | |
| 704 | R | B | -2.1832 | |
| 705 | H | B | -0.8920 | |
| 706 | W | B | 0.5258 | |
| 707 | I | B | 0.9424 | |
| 708 | G | B | -0.3179 | |
| 709 | S | B | -0.3581 | |
| 710 | D | B | -0.2124 | |
| 711 | C | B | 0.0000 | |
| 712 | N | B | -0.5263 | |
| 713 | T | B | 0.0951 | |
| 714 | Y | B | 1.6303 | |
| 715 | F | B | 1.7860 | |
| 716 | P | B | -0.1542 | |
| 717 | H | B | -1.2519 | |
| 718 | N | B | -1.4521 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine