Project name: test8

Chain sequence(s)	A: SHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGPTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDKEGLLSMANAGSNTNGSQFFITTVPTPHLDGKHVVFGQVIKGMGVAKILENVEVKGEKPAKLCVIAECGELKEGDDWGIFPKDGSGDSHPDFPEDADVDLKDVDKILLISEDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAELLKVKQKIKAQKDKEKAAY
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.4514
• Maximal score value: 1.948
• Average score: -0.4153
• Total score value: -151.187

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	S	A	-0.3712
3	H	A	-0.9000
4	P	A	-0.2837
5	S	A	0.0000
6	P	A	-0.2500
7	Q	A	-1.1929
8	A	A	-0.4718
9	K	A	-1.7073
10	P	A	-0.5639
11	S	A	-0.1392
12	N	A	-0.3980
13	P	A	-0.3562
14	S	A	-0.2592
15	N	A	0.0000
16	P	A	-0.0840
17	R	A	-0.2226
18	V	A	0.0000
19	F	A	0.2055
20	F	A	0.0000
21	D	A	0.0000
22	V	A	0.0000
23	D	A	-0.3449
24	I	A	0.0795
25	G	A	-0.5136
26	G	A	-0.8868
27	E	A	-2.0795
28	R	A	-1.2454
29	V	A	0.1583
30	G	A	-0.0658
31	R	A	-0.2260
32	I	A	0.0000
33	V	A	0.0000
34	L	A	0.0000
35	E	A	0.0000
36	L	A	0.0000
37	F	A	0.0000
38	A	A	-0.2909
39	D	A	-1.3251
40	I	A	0.2627
41	V	A	0.0000
42	P	A	-0.4066
43	K	A	-0.9405
44	T	A	0.0000
45	A	A	0.0000
46	E	A	-0.8444
47	N	A	0.0000
48	F	A	0.0000
49	R	A	-0.3155
50	A	A	0.0000
51	L	A	0.0000
52	C	A	0.0000
53	T	A	-0.0452
54	G	A	-0.4434
55	E	A	-2.1389
56	K	A	-2.0642
57	G	A	-0.1540
58	I	A	1.9480
59	G	A	0.0000
60	P	A	-0.2683
61	T	A	-0.1230
62	T	A	-0.1219
63	G	A	-0.6178
64	K	A	-0.9285
65	P	A	-0.0291
66	L	A	0.0000
67	H	A	-0.1950
68	F	A	0.0000
69	K	A	-1.4895
70	G	A	-0.5792
71	C	A	0.0000
72	P	A	0.0000
73	F	A	0.0000
74	H	A	0.0000
75	R	A	-0.6371
76	I	A	0.0000
77	I	A	0.2870
78	K	A	-1.8986
79	K	A	-1.9431
80	F	A	0.0645
81	M	A	0.0000
82	I	A	0.0000
83	Q	A	0.0000
84	G	A	0.0000
85	G	A	0.0000
86	D	A	0.0000
87	F	A	0.0000
88	S	A	-0.2732
89	N	A	-1.4058
90	Q	A	-1.1479
91	N	A	-1.3709
92	G	A	-0.4457
93	T	A	-0.1258
94	G	A	-0.1146
95	G	A	-0.0756
96	E	A	0.0000
97	S	A	0.0000
98	I	A	0.0000
99	Y	A	0.6894
100	G	A	-0.3390
101	E	A	-2.0683
102	K	A	-1.5561
103	F	A	0.0000
104	E	A	-2.0299
105	D	A	-0.8235
106	E	A	-0.6855
107	N	A	-0.4418
108	F	A	0.5136
109	H	A	-0.1711
110	Y	A	-0.1238
111	K	A	-0.5305
112	H	A	0.0000
113	D	A	-0.6840
114	K	A	-0.6202
115	E	A	-1.1839
116	G	A	0.0000
117	L	A	0.0000
118	L	A	0.0000
119	S	A	0.0000
120	M	A	0.0000
121	A	A	-0.0386
122	N	A	-0.2321
123	A	A	-0.0146
124	G	A	-0.1774
125	S	A	-0.4304
126	N	A	-1.3824
127	T	A	-0.2117
128	N	A	0.0000
129	G	A	0.0000
130	S	A	0.0000
131	Q	A	-0.1262
132	F	A	0.0000
133	F	A	0.0000
134	I	A	0.0000
135	T	A	0.0000
136	T	A	0.0000
137	V	A	0.1164
138	P	A	-0.2236
139	T	A	0.0000
140	P	A	-0.4362
141	H	A	-1.0368
142	L	A	0.0000
143	D	A	-0.7865
144	G	A	-0.8499
145	K	A	-1.4594
146	H	A	0.0000
147	V	A	0.0000
148	V	A	0.0000
149	F	A	0.0000
150	G	A	0.0000
151	Q	A	0.0000
152	V	A	0.0000
153	I	A	0.0000
154	K	A	-0.2552
155	G	A	0.0000
156	M	A	0.1801
157	G	A	-0.1163
158	V	A	0.0000
159	A	A	0.0000
160	K	A	-0.5183
161	I	A	0.7370
162	L	A	0.0000
163	E	A	0.0000
164	N	A	-1.2399
165	V	A	-0.3018
166	E	A	-1.1221
167	V	A	0.3475
168	K	A	-1.6201
169	G	A	-0.9578
170	E	A	-1.2536
171	K	A	-1.3919
172	P	A	-0.0958
173	A	A	-0.1406
174	K	A	-0.7627
175	L	A	1.3482
176	C	A	0.0000
177	V	A	0.2040
178	I	A	0.0000
179	A	A	-0.1146
180	E	A	-0.6709
181	C	A	0.0000
182	G	A	-0.1013
183	E	A	-0.2947
184	L	A	0.0000
185	K	A	-2.0374
186	E	A	-2.2211
187	G	A	-1.0873
188	D	A	-1.9570
189	D	A	-1.9985
190	W	A	0.0827
191	G	A	0.0768
192	I	A	0.4613
193	F	A	1.0701
194	P	A	-0.0421
195	K	A	-1.2175
196	D	A	-0.9921
197	G	A	-0.6026
198	S	A	-0.2147
199	G	A	-0.4742
200	D	A	0.0000
201	S	A	-0.2356
202	H	A	-0.1688
203	P	A	0.0051
204	D	A	-0.3432
205	F	A	0.2019
206	P	A	0.0000
207	E	A	-1.8594
208	D	A	-0.5479
209	A	A	-0.3653
210	D	A	-1.7552
211	V	A	-0.4802
212	D	A	-1.7200
213	L	A	-0.4438
214	K	A	-1.9069
215	D	A	-1.6470
216	V	A	0.0000
217	D	A	-1.9763
218	K	A	-1.3516
219	I	A	0.0000
220	L	A	0.4891
221	L	A	1.5856
222	I	A	0.0000
223	S	A	0.0000
224	E	A	-1.3966
225	D	A	-1.2534
226	L	A	0.0000
227	K	A	-0.5906
228	N	A	-1.2995
229	I	A	-0.0155
230	G	A	0.0000
231	N	A	-0.2770
232	T	A	-0.0778
233	F	A	0.3223
234	F	A	0.0622
235	K	A	-1.6689
236	S	A	-0.7393
237	Q	A	-1.3329
238	N	A	-0.7127
239	W	A	-0.2774
240	E	A	-1.7652
241	M	A	-0.3767
242	A	A	0.0000
243	I	A	-0.0102
244	K	A	-1.6277
245	K	A	0.0000
246	Y	A	0.0000
247	T	A	-0.0268
248	K	A	0.0000
249	V	A	0.0000
250	L	A	0.1032
251	R	A	-0.5302
252	Y	A	0.0000
253	V	A	0.0000
254	E	A	-1.8326
255	G	A	-0.4024
256	S	A	0.0000
257	R	A	-1.8332
258	A	A	-0.2810
259	A	A	0.0311
260	A	A	-0.5304
261	E	A	-2.1467
262	D	A	-2.1124
263	A	A	-0.5544
264	D	A	-1.4880
265	G	A	0.0000
266	A	A	-0.2037
267	K	A	-1.2649
268	L	A	0.0000
269	Q	A	-0.6939
270	P	A	-0.3716
271	V	A	0.0000
272	A	A	0.0000
273	L	A	0.2144
274	S	A	0.0014
275	C	A	0.0000
276	V	A	0.0000
277	L	A	0.0000
278	N	A	-0.2470
279	I	A	0.0000
280	G	A	0.0000
281	A	A	-0.0156
282	C	A	0.0000
283	K	A	-0.1835
284	L	A	-0.1698
285	K	A	-1.5973
286	M	A	-0.0130
287	S	A	-0.2839
288	D	A	-0.8326
289	W	A	0.0245
290	Q	A	-0.8690
291	G	A	-0.2259
292	A	A	0.0000
293	V	A	0.0000
294	D	A	-1.2687
295	S	A	0.0000
296	C	A	0.0000
297	L	A	0.4712
298	E	A	-1.2725
299	A	A	0.0000
300	L	A	0.0000
301	E	A	-1.6803
302	I	A	0.3420
303	D	A	-0.3312
304	P	A	-0.3706
305	S	A	-0.2784
306	N	A	-0.1934
307	T	A	-0.2590
308	K	A	-1.1890
309	A	A	0.0000
310	L	A	0.0000
311	Y	A	0.1068
312	R	A	-0.4954
313	R	A	-0.3267
314	A	A	0.0000
315	Q	A	-0.4460
316	G	A	0.0000
317	W	A	0.1492
318	Q	A	0.0000
319	G	A	0.0347
320	L	A	0.3124
321	K	A	-1.7394
322	E	A	-1.1546
323	Y	A	-0.3532
324	D	A	-1.8771
325	Q	A	-0.9446
326	A	A	0.0000
327	L	A	0.2924
328	A	A	0.0947
329	D	A	0.0000
330	L	A	0.0000
331	K	A	-1.5100
332	K	A	-1.1371
333	A	A	0.0000
334	Q	A	-0.5846
335	E	A	-1.6597
336	I	A	0.7684
337	A	A	0.1419
338	P	A	-0.6120
339	E	A	-1.9721
340	D	A	-1.2216
341	K	A	-1.8540
342	A	A	-0.2837
343	I	A	0.0000
344	Q	A	-0.7063
345	A	A	-0.0835
346	E	A	0.0000
347	L	A	0.0000
348	L	A	1.2550
349	K	A	-1.2552
350	V	A	0.0000
351	K	A	-1.7644
352	Q	A	-1.6228
353	K	A	-0.8943
354	I	A	0.1278
355	K	A	-1.5898
356	A	A	-0.3781
357	Q	A	-0.7623
358	K	A	-1.8964
359	D	A	-1.2394
360	K	A	-2.1527
361	E	A	-2.4514
362	K	A	-2.0257
363	A	A	-0.2365
364	A	A	0.3100
365	Y	A	1.3260