Project name: TTRed

Chain sequence(s)	A: CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEQFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN; B: CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEQFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6547
• Maximal score value: 1.8702
• Average score: -0.703
• Total score value: -160.9887

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
10	C	A	-0.5578
11	P	A	0.0000
12	L	A	0.0000
13	M	A	-0.3667
14	V	A	0.0000
15	K	A	-0.2934
16	V	A	0.0000
17	L	A	0.2870
18	D	A	0.0000
19	A	A	-0.0625
20	V	A	-0.1942
21	R	A	-1.7012
22	G	A	-1.1306
23	S	A	-0.8314
24	P	A	-0.7253
25	A	A	0.0000
26	I	A	-0.9076
27	N	A	-1.9865
28	V	A	0.0000
29	A	A	-1.2543
30	V	A	0.0000
31	H	A	-0.7081
32	V	A	0.0000
33	F	A	-0.4657
34	R	A	-1.0639
35	K	A	-1.6338
36	A	A	-1.7006
37	A	A	-1.6190
38	D	A	-2.8241
39	D	A	-2.9020
40	T	A	-1.8862
41	W	A	-1.1896
42	E	A	-1.8172
43	P	A	-0.8319
44	F	A	-0.4157
45	A	A	-0.3054
46	S	A	-0.7266
47	G	A	-1.4597
48	K	A	-2.5375
49	T	A	0.0000
50	S	A	-1.8375
51	E	A	-2.1952
52	S	A	-1.1677
53	G	A	0.0000
54	E	A	-1.3042
55	L	A	-1.3980
56	H	A	-1.2727
57	G	A	-0.7662
58	L	A	0.0000
59	T	A	0.0000
60	T	A	-1.7491
61	E	A	-3.1660
62	E	A	-3.0949
63	Q	A	-2.4913
64	F	A	0.0000
65	V	A	-1.3738
66	E	A	-2.2283
67	G	A	-1.1320
68	I	A	-0.5996
69	Y	A	0.0000
70	K	A	-0.3808
71	V	A	0.0000
72	E	A	-0.4687
73	I	A	0.0000
74	D	A	-1.0404
75	T	A	0.0000
76	K	A	-1.2722
77	S	A	-1.1030
78	Y	A	-0.6045
79	W	A	0.0000
80	K	A	-1.5290
81	A	A	-0.3988
82	L	A	0.4316
83	G	A	-0.3124
84	I	A	-0.0636
85	S	A	-0.4257
86	P	A	-0.4995
87	F	A	0.0000
88	H	A	0.0000
89	E	A	-0.5433
90	H	A	-0.6597
91	A	A	0.0000
92	E	A	0.0000
93	V	A	0.0000
94	V	A	0.0000
95	F	A	0.0000
96	T	A	-0.8409
97	A	A	0.0000
98	N	A	0.0000
99	D	A	-2.4786
100	S	A	-1.5627
101	G	A	-1.3931
102	P	A	-2.2839
103	R	A	-2.6458
104	R	A	-2.1838
105	Y	A	0.0000
106	T	A	0.1796
107	I	A	0.0000
108	A	A	0.3498
109	A	A	0.0000
110	L	A	0.8724
111	L	A	0.0000
112	S	A	0.2259
113	P	A	0.0677
114	Y	A	0.7091
115	S	A	0.4335
116	Y	A	0.0000
117	S	A	0.2682
118	T	A	0.0000
119	T	A	0.6589
120	A	A	0.0000
121	V	A	1.8702
122	V	A	0.5321
123	T	A	-0.8358
124	N	A	-1.9112
10	C	B	-0.6517
11	P	B	0.0000
12	L	B	0.0000
13	M	B	-0.2834
14	V	B	0.0000
15	K	B	-0.3009
16	V	B	0.0000
17	L	B	0.3808
18	D	B	0.0000
19	A	B	0.3922
20	V	B	0.7562
21	R	B	-1.2421
22	G	B	-0.7858
23	S	B	-0.7097
24	P	B	-0.7671
25	A	B	0.0000
26	I	B	-0.9937
27	N	B	-2.0468
28	V	B	0.0000
29	A	B	-1.2327
30	V	B	0.0000
31	H	B	-0.6973
32	V	B	0.0000
33	F	B	-0.6021
34	R	B	-1.2713
35	K	B	-1.7987
36	A	B	-1.8567
37	A	B	-1.6903
38	D	B	-2.6951
39	D	B	-2.9734
40	T	B	-2.0318
41	W	B	-1.4312
42	E	B	-2.0911
43	P	B	-1.0451
44	F	B	-0.5034
45	A	B	-0.3114
46	S	B	-0.6931
47	G	B	-1.4292
48	K	B	-2.5483
49	T	B	0.0000
50	S	B	-1.8518
51	E	B	-2.2197
52	S	B	-1.1876
53	G	B	0.0000
54	E	B	-1.3029
55	L	B	-1.3500
56	H	B	-1.2145
57	G	B	-0.7057
58	L	B	-0.2833
59	T	B	-1.0810
60	T	B	-1.7888
61	E	B	-3.3699
62	E	B	-3.1353
63	Q	B	-2.6024
64	F	B	0.0000
65	V	B	-1.7462
66	E	B	-2.4611
67	G	B	-1.2639
68	I	B	-0.5077
69	Y	B	0.0000
70	K	B	0.0000
71	V	B	0.0000
72	E	B	-0.5101
73	I	B	0.0000
74	D	B	-1.0973
75	T	B	0.0000
76	K	B	-1.2737
77	S	B	-1.2215
78	Y	B	0.0000
79	W	B	0.0000
80	K	B	-1.7183
81	A	B	-0.6630
82	L	B	-0.0619
83	G	B	-0.5566
84	I	B	-0.2181
85	S	B	-0.4637
86	P	B	-0.4422
87	F	B	0.0000
88	H	B	0.0000
89	E	B	-0.5758
90	H	B	-0.6885
91	A	B	0.0000
92	E	B	-0.4346
93	V	B	0.0000
94	V	B	0.0000
95	F	B	0.0000
96	T	B	-0.9733
97	A	B	0.0000
98	N	B	-2.7932
99	D	B	-3.6547
100	S	B	-2.1805
101	G	B	-1.8313
102	P	B	-1.8488
103	R	B	-2.5067
104	R	B	-2.0377
105	Y	B	0.0000
106	T	B	0.1428
107	I	B	0.0000
108	A	B	0.3501
109	A	B	0.0000
110	L	B	0.9057
111	L	B	0.0000
112	S	B	0.5486
113	P	B	0.3235
114	Y	B	0.9638
115	S	B	0.5441
116	Y	B	0.0000
117	S	B	0.2568
118	T	B	0.0000
119	T	B	0.5716
120	A	B	0.0000
121	V	B	1.6505
122	V	B	0.4752
123	T	B	-0.3175