| Chain sequence(s) |
A: ANSLSVHQLAAQGEEMLYLATRIEQENVINHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSSLACSKGYTDIVKMLLDCGVDDVNEEYDWNGGTPLLYAVHGNHVKCVKMLLESGADPTIETDDSGYNSSMDLAVALGYRSVQQVIESHLLKLLQN B: HTPRLPTLPKRVP |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 148 | A | A | -0.5239 | |
| 149 | N | A | -1.2068 | |
| 150 | S | A | -0.7232 | |
| 151 | L | A | -0.2621 | |
| 152 | S | A | -0.4687 | |
| 153 | V | A | 0.0000 | |
| 154 | H | A | -0.6654 | |
| 155 | Q | A | -0.9412 | |
| 156 | L | A | 0.0000 | |
| 157 | A | A | 0.0000 | |
| 158 | A | A | -1.1317 | |
| 159 | Q | A | -1.7267 | |
| 160 | G | A | -0.7608 | |
| 161 | E | A | -0.4055 | |
| 162 | M | A | 0.7360 | |
| 163 | L | A | 1.7918 | |
| 164 | Y | A | 1.0623 | |
| 165 | L | A | 0.0000 | |
| 166 | A | A | 0.1193 | |
| 167 | T | A | -0.5939 | |
| 168 | R | A | -1.5429 | |
| 169 | I | A | -1.9934 | |
| 170 | E | A | -3.0981 | |
| 171 | Q | A | -3.2442 | |
| 172 | E | A | -3.4981 | |
| 173 | N | A | -2.7995 | |
| 174 | V | A | -1.7403 | |
| 175 | I | A | -1.3082 | |
| 176 | N | A | -1.1632 | |
| 177 | H | A | -1.2715 | |
| 178 | T | A | -1.3909 | |
| 179 | D | A | -1.9650 | |
| 180 | E | A | -2.6963 | |
| 181 | E | A | -2.5739 | |
| 182 | G | A | -1.9496 | |
| 183 | F | A | 0.0000 | |
| 184 | T | A | 0.0000 | |
| 185 | P | A | 0.0000 | |
| 186 | L | A | 0.0000 | |
| 187 | M | A | 0.0000 | |
| 188 | W | A | -0.5103 | |
| 189 | A | A | 0.0000 | |
| 190 | A | A | 0.0000 | |
| 191 | A | A | 0.0000 | |
| 192 | H | A | -0.7810 | |
| 193 | G | A | -0.6820 | |
| 194 | Q | A | -0.6485 | |
| 195 | I | A | 0.0229 | |
| 196 | A | A | -0.1499 | |
| 197 | V | A | 0.0000 | |
| 198 | V | A | 0.0000 | |
| 199 | E | A | -1.7603 | |
| 200 | F | A | -0.9774 | |
| 201 | L | A | 0.0000 | |
| 202 | L | A | -1.3746 | |
| 203 | Q | A | -2.1794 | |
| 204 | N | A | -1.9665 | |
| 205 | G | A | -1.4532 | |
| 206 | A | A | 0.0000 | |
| 207 | D | A | -1.3198 | |
| 208 | P | A | -0.9517 | |
| 209 | Q | A | -1.4139 | |
| 210 | L | A | -0.5355 | |
| 211 | L | A | -0.6595 | |
| 212 | G | A | -1.6224 | |
| 213 | K | A | -2.3529 | |
| 214 | G | A | -1.0992 | |
| 215 | R | A | -1.0495 | |
| 216 | E | A | -1.0833 | |
| 217 | S | A | -0.7164 | |
| 218 | A | A | 0.0000 | |
| 219 | L | A | 0.0000 | |
| 220 | S | A | 0.0000 | |
| 221 | L | A | 0.0000 | |
| 222 | A | A | 0.0000 | |
| 223 | C | A | 0.0000 | |
| 224 | S | A | -1.1313 | |
| 225 | K | A | -1.6489 | |
| 226 | G | A | -1.3467 | |
| 227 | Y | A | -1.0324 | |
| 228 | T | A | -1.5877 | |
| 229 | D | A | -2.0823 | |
| 230 | I | A | 0.0000 | |
| 231 | V | A | 0.0000 | |
| 232 | K | A | -2.0336 | |
| 233 | M | A | -1.5647 | |
| 234 | L | A | 0.0000 | |
| 235 | L | A | -1.3221 | |
| 236 | D | A | -1.9202 | |
| 237 | C | A | -1.1381 | |
| 238 | G | A | -1.3038 | |
| 239 | V | A | -1.5946 | |
| 240 | D | A | -2.3034 | |
| 241 | V | A | 0.0000 | |
| 242 | N | A | -1.3702 | |
| 243 | E | A | -1.2878 | |
| 244 | Y | A | 0.1409 | |
| 245 | D | A | 0.0000 | |
| 246 | W | A | 0.3344 | |
| 247 | N | A | -0.8960 | |
| 248 | G | A | -0.9877 | |
| 249 | G | A | 0.0000 | |
| 250 | T | A | 0.0000 | |
| 251 | P | A | 0.0000 | |
| 252 | L | A | 0.0000 | |
| 253 | L | A | 0.0000 | |
| 254 | Y | A | 0.0000 | |
| 255 | A | A | 0.0000 | |
| 256 | V | A | 0.0000 | |
| 257 | H | A | -0.6303 | |
| 258 | G | A | -0.9562 | |
| 259 | N | A | -1.5130 | |
| 260 | H | A | -1.3395 | |
| 261 | V | A | -1.3073 | |
| 262 | K | A | -2.1072 | |
| 263 | C | A | 0.0000 | |
| 264 | V | A | 0.0000 | |
| 265 | K | A | -1.9308 | |
| 266 | M | A | -1.6846 | |
| 267 | L | A | 0.0000 | |
| 268 | L | A | 0.0000 | |
| 269 | E | A | -2.3406 | |
| 270 | S | A | -1.9806 | |
| 271 | G | A | -1.5642 | |
| 272 | A | A | 0.0000 | |
| 273 | D | A | -1.3079 | |
| 274 | P | A | 0.0000 | |
| 275 | T | A | -0.6530 | |
| 276 | I | A | -1.0393 | |
| 277 | E | A | -2.4683 | |
| 278 | T | A | -2.4374 | |
| 279 | D | A | -2.9074 | |
| 280 | S | A | -2.3568 | |
| 281 | G | A | -2.0564 | |
| 282 | Y | A | 0.0000 | |
| 283 | N | A | -1.3033 | |
| 284 | S | A | 0.0000 | |
| 285 | M | A | -0.2914 | |
| 286 | D | A | -0.1398 | |
| 287 | L | A | 0.0000 | |
| 288 | A | A | 0.0000 | |
| 289 | V | A | 1.1952 | |
| 290 | A | A | 0.9543 | |
| 291 | L | A | 0.5758 | |
| 292 | G | A | -0.2252 | |
| 293 | Y | A | -0.6942 | |
| 294 | R | A | -1.8779 | |
| 295 | S | A | -1.6097 | |
| 296 | V | A | 0.0000 | |
| 297 | Q | A | 0.0000 | |
| 298 | Q | A | -1.8673 | |
| 299 | V | A | -1.4002 | |
| 300 | I | A | 0.0000 | |
| 301 | E | A | -1.4570 | |
| 302 | S | A | -0.8239 | |
| 303 | H | A | -0.9250 | |
| 304 | L | A | 0.0284 | |
| 305 | L | A | 0.2595 | |
| 306 | K | A | -1.0998 | |
| 307 | L | A | 0.6241 | |
| 308 | L | A | 0.9982 | |
| 309 | Q | A | -1.0052 | |
| 310 | N | A | -1.2242 | |
| 498 | H | B | -1.3184 | |
| 499 | T | B | -1.4693 | |
| 500 | P | B | 0.0000 | |
| 501 | R | B | -2.0771 | |
| 502 | L | B | 0.0000 | |
| 503 | P | B | -0.9504 | |
| 504 | T | B | -0.8868 | |
| 505 | L | B | 0.0000 | |
| 506 | P | B | -1.4015 | |
| 507 | K | B | -2.8663 | |
| 508 | R | B | -2.3472 | |
| 509 | V | B | 0.1580 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine