Project name: 3hmx:H

Chain sequence(s)	H: EVQLVQSGAEVKKPGESLKISCKGSGYSFTTYWLGWVRQMPGKGLDWIGIMSPVDSDIRYSPSFQGQVTMSVDKSITTAYLQWNSLKASDTAMYYCARRRPGQGYFDFWGQGTLVTVSSSSTKGPSVFPLAPSSKSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.856
• Maximal score value: 2.4851
• Average score: -0.5362
• Total score value: -116.3495

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.0391
2	V	H	-0.7514
3	Q	H	-0.9644
4	L	H	0.0000
5	V	H	0.8368
6	Q	H	0.0000
7	S	H	-0.4277
8	G	H	-0.4457
9	A	H	-0.1376
10	E	H	-0.4333
11	V	H	0.1919
12	K	H	-1.1109
13	K	H	-1.7456
14	P	H	-1.8084
15	G	H	-1.9937
16	E	H	-2.2496
17	S	H	-2.0683
18	L	H	0.0000
19	K	H	-2.0235
20	I	H	0.0000
21	S	H	-0.4611
22	C	H	0.0000
23	K	H	-0.7983
24	G	H	0.0000
25	S	H	-0.7245
26	G	H	-1.2118
27	Y	H	-0.5467
28	S	H	-0.1854
29	F	H	0.0000
30	T	H	0.0476
31	T	H	0.1202
32	Y	H	0.0643
33	W	H	0.0885
34	L	H	0.0000
35	G	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.0201
39	Q	H	-0.4447
40	M	H	-0.6987
41	P	H	-1.0425
42	G	H	-1.3862
43	K	H	-2.0794
44	G	H	-0.9545
45	L	H	0.4385
46	D	H	0.1602
47	W	H	0.9067
48	I	H	0.0000
49	G	H	0.0000
50	I	H	0.0000
51	M	H	0.0000
52	S	H	0.0000
53	P	H	0.0000
54	V	H	0.2176
55	D	H	-1.5831
56	S	H	-1.5105
57	D	H	-2.2149
58	I	H	-1.2935
59	R	H	-1.9961
60	Y	H	-0.9769
61	S	H	-0.7620
62	P	H	-1.1104
63	S	H	-0.7656
64	F	H	0.0000
65	Q	H	-1.9361
66	G	H	-1.3478
67	Q	H	-1.4563
68	V	H	0.0000
69	T	H	-0.8642
70	M	H	0.0000
71	S	H	-0.4240
72	V	H	-0.4524
73	D	H	-1.0380
74	K	H	-1.3317
75	S	H	-0.3058
76	I	H	0.2908
77	T	H	-0.6237
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.5770
81	L	H	0.0000
82	Q	H	-1.5446
83	W	H	0.0000
84	N	H	-2.2368
85	S	H	-1.8748
86	L	H	0.0000
87	K	H	-2.0455
88	A	H	-1.0297
89	S	H	-0.6205
90	D	H	0.0000
91	T	H	-0.2150
92	A	H	0.0000
93	M	H	0.3287
94	Y	H	0.0000
95	Y	H	0.4659
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	R	H	-0.6808
100	R	H	-1.2991
101	P	H	-1.1460
102	G	H	-1.2819
103	Q	H	-1.5791
104	G	H	-0.7056
105	Y	H	0.2657
106	F	H	0.0000
107	D	H	-0.1367
108	F	H	0.7710
109	W	H	0.8460
110	G	H	0.0000
111	Q	H	-0.5476
112	G	H	-0.0623
113	T	H	0.0000
114	L	H	0.4465
115	V	H	0.0000
116	T	H	-0.1581
117	V	H	0.0000
118	S	H	-0.7358
119	S	H	-0.8901
120	S	H	-0.5451
121	S	H	-0.6008
122	T	H	-0.6539
123	K	H	-1.2102
124	G	H	-1.4800
125	P	H	0.0000
126	S	H	-0.0667
127	V	H	0.0000
128	F	H	0.8726
129	P	H	0.1772
130	L	H	0.4730
131	A	H	-0.6804
132	P	H	0.0000
133	S	H	-1.1345
134	S	H	-1.4301
135	K	H	-2.1320
136	S	H	-1.2714
140	G	H	-1.1015
141	T	H	-0.8396
142	A	H	0.0000
143	A	H	-0.1381
144	L	H	0.0000
145	G	H	0.0000
146	C	H	0.0000
147	L	H	0.6102
148	V	H	0.0000
149	K	H	-0.2734
150	D	H	-0.5763
151	Y	H	0.0000
152	F	H	0.0000
153	P	H	0.0000
154	E	H	-0.7492
155	P	H	-1.0675
156	V	H	-0.9238
157	T	H	-0.8032
158	V	H	-0.5141
159	S	H	-0.5010
160	W	H	0.0000
161	N	H	-0.8804
162	S	H	-0.6432
163	G	H	-0.4942
164	A	H	-0.2226
165	L	H	-0.0117
166	T	H	-0.3092
167	S	H	-0.3916
168	G	H	-0.4884
169	V	H	-0.0490
170	H	H	-0.5073
171	T	H	0.2000
172	F	H	1.0716
173	P	H	0.7363
174	A	H	1.2345
175	V	H	2.4851
176	L	H	2.1230
177	Q	H	0.7500
178	S	H	0.1612
179	S	H	-0.1927
180	G	H	0.1984
181	L	H	0.1936
182	Y	H	0.7148
183	S	H	0.0000
184	L	H	0.0000
185	S	H	0.6649
186	S	H	0.0000
187	V	H	0.4115
188	V	H	0.0000
189	T	H	-0.2462
190	V	H	0.0000
191	P	H	-0.6534
192	S	H	-0.8795
193	S	H	-0.7439
194	S	H	-0.5479
195	L	H	-0.5678
196	G	H	-0.9656
197	T	H	-0.8101
198	Q	H	-1.3082
199	T	H	-1.2963
200	Y	H	0.0000
201	I	H	-1.5783
202	C	H	0.0000
203	N	H	-1.6298
204	V	H	0.0000
205	N	H	-2.3750
206	H	H	0.0000
207	K	H	-2.8560
208	P	H	-1.6039
209	S	H	-1.8927
210	N	H	-2.5659
211	T	H	-2.1977
212	K	H	-2.8430
213	V	H	-1.9261
214	D	H	-2.5480
215	K	H	-2.0664
216	R	H	-2.5880
217	V	H	0.0000
218	E	H	-2.4002
219	P	H	-1.6740
220	K	H	-2.1542