Project name: 52a17de98051609

Chain sequence(s)	A: AMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL; C: YGALDMADFEFEQMFTDALGIDEYGG; B: AMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3337
• Maximal score value: 1.4149
• Average score: -0.8437
• Total score value: -133.2995

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
61	A	A	0.0094
62	M	A	0.8317
63	F	A	0.1465
64	Q	A	-0.6741
65	I	A	0.0000
66	G	A	-1.5665
67	K	A	-1.8787
68	M	A	-0.5171
69	R	A	-0.9244
70	Y	A	-0.0645
71	V	A	0.0000
72	S	A	0.0000
73	V	A	0.0000
74	R	A	-1.3549
75	D	A	-2.3423
76	F	A	-2.0447
77	K	A	-2.4715
78	G	A	-1.7914
79	K	A	-1.3901
80	V	A	-1.3044
81	L	A	0.0000
82	I	A	0.0000
83	D	A	0.0000
84	I	A	0.0000
85	R	A	0.0000
86	E	A	-0.8816
87	Y	A	0.0000
88	W	A	1.4149
89	M	A	1.1023
90	D	A	0.0000
91	P	A	-0.8105
92	E	A	-1.8595
93	G	A	-1.2496
94	E	A	-0.5664
95	M	A	0.6401
96	K	A	0.0000
97	P	A	-0.1374
98	G	A	-0.8445
99	R	A	-2.4087
100	K	A	-2.0201
101	G	A	0.0000
102	I	A	0.0000
103	S	A	0.0000
104	L	A	0.0000
105	N	A	0.0000
106	P	A	-0.8829
107	E	A	-1.2800
108	Q	A	0.0000
109	W	A	0.0000
110	S	A	-1.2788
111	Q	A	-1.5592
112	L	A	0.0000
113	K	A	-1.8817
114	E	A	-2.6457
115	Q	A	-2.2018
116	I	A	-1.6720
117	S	A	-1.8421
118	D	A	-2.4189
119	I	A	0.0000
120	D	A	-1.8410
121	D	A	-2.2330
122	A	A	0.0000
123	V	A	-1.9480
124	R	A	-2.4262
125	K	A	-2.2315
126	L	A	-0.9944
61	A	B	-0.3712
62	M	B	0.3505
63	F	B	-0.1226
64	Q	B	-0.5693
65	I	B	0.0000
66	G	B	0.0000
67	K	B	-0.4651
68	M	B	0.0763
69	R	B	0.0000
70	Y	B	0.0018
71	V	B	0.0000
72	S	B	0.0000
73	V	B	0.0000
74	R	B	-1.8406
75	D	B	-2.5209
76	F	B	-1.6787
77	K	B	-2.4718
78	G	B	-2.1679
79	K	B	-2.5237
80	V	B	-1.8582
81	L	B	-1.1053
82	I	B	0.0000
83	D	B	-0.3552
84	I	B	0.0000
85	R	B	-0.7802
86	E	B	0.0000
87	Y	B	-0.5013
88	W	B	0.1130
89	M	B	-0.2960
90	D	B	-1.3894
91	P	B	-1.4366
92	E	B	-2.5716
93	G	B	-2.1867
94	E	B	-2.5590
95	M	B	-1.2147
96	K	B	-1.8543
97	P	B	-1.3296
98	G	B	-1.2869
99	R	B	-2.5415
100	K	B	-1.6913
101	G	B	0.0000
102	I	B	0.0000
103	S	B	-0.3993
104	L	B	0.0000
105	N	B	-1.1129
106	P	B	-1.5796
107	E	B	-2.1484
108	Q	B	-1.9921
109	W	B	0.0000
110	S	B	-1.6964
111	Q	B	-1.8887
112	L	B	0.0000
113	K	B	-1.7820
114	E	B	-2.5328
115	Q	B	-1.8902
116	I	B	-1.7093
117	S	B	-1.9015
118	D	B	-2.4645
119	I	B	0.0000
120	D	B	-2.4528
121	D	B	-3.3337
122	A	B	-2.2226
123	V	B	0.0000
124	R	B	-2.9346
125	K	B	-2.3429
126	L	B	-0.2425
465	Y	C	0.2456
466	G	C	-0.4301
467	A	C	0.1200
468	L	C	0.3661
469	D	C	-0.1839
470	M	C	0.7481
471	A	C	0.0000
472	D	C	0.0782
473	F	C	1.1415
474	E	C	-0.2292
475	F	C	0.0000
476	E	C	-1.2593
477	Q	C	-1.1625
478	M	C	0.0000
479	F	C	0.0000
480	T	C	-0.8084
481	D	C	-0.5946
482	A	C	0.0000
483	L	C	0.0000
484	G	C	0.0000
485	I	C	-0.0088
486	D	C	0.0000
487	E	C	-0.7576
488	Y	C	0.5677
489	G	C	-0.3153
490	G	C	-0.7470