Project name: 4g3y:L
Status: done
submitted: 2019-03-20 20:15:00, status changed: 2019-03-20 20:23:56
Settings
|
Chain sequence(s)
|
L: DILLTQSPAILSVSPGERVSFSCRASQFVGSSIHWYQQRTNGSPRLLIKYASESMSGIPSRFSGSGSGTDFTLSINTVESEDIADYYCQQSHSWPFTFGSGTNLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6609
-
Maximal score value
-
2.1102
-
Average score
-
-0.726
-
Total score value
-
-155.3561
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.2428 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
L |
L |
1.1453 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
0.0745 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.0377 |
|
| 8 |
P |
L |
0.2375 |
|
| 9 |
A |
L |
0.5587 |
|
| 10 |
I |
L |
1.5459 |
|
| 11 |
L |
L |
0.8517 |
|
| 12 |
S |
L |
0.1350 |
|
| 13 |
V |
L |
0.0000 |
|
| 14 |
S |
L |
-1.7054 |
|
| 15 |
P |
L |
-2.0889 |
|
| 16 |
G |
L |
-2.2996 |
|
| 17 |
E |
L |
-3.3064 |
|
| 18 |
R |
L |
-3.4210 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
S |
L |
-0.7290 |
|
| 21 |
F |
L |
0.0000 |
|
| 22 |
S |
L |
-0.6297 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-1.0002 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.3786 |
|
| 27 |
Q |
L |
-0.6083 |
|
| 28 |
F |
L |
0.8305 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
G |
L |
-0.0254 |
|
| 31 |
S |
L |
-0.0962 |
|
| 32 |
S |
L |
0.1309 |
|
| 33 |
I |
L |
0.0000 |
|
| 34 |
H |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.5925 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-2.2185 |
|
| 39 |
R |
L |
-3.3404 |
|
| 40 |
T |
L |
-2.3421 |
|
| 41 |
N |
L |
-2.1233 |
|
| 42 |
G |
L |
-1.9036 |
|
| 43 |
S |
L |
-1.5178 |
|
| 44 |
P |
L |
-1.7521 |
|
| 45 |
R |
L |
-2.0732 |
|
| 46 |
L |
L |
-0.5789 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
K |
L |
-0.5869 |
|
| 50 |
Y |
L |
0.1861 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-1.0442 |
|
| 53 |
E |
L |
-1.8459 |
|
| 54 |
S |
L |
-1.0107 |
|
| 55 |
M |
L |
-0.4132 |
|
| 56 |
S |
L |
-0.4705 |
|
| 57 |
G |
L |
-0.4349 |
|
| 58 |
I |
L |
-0.2873 |
|
| 59 |
P |
L |
-0.3349 |
|
| 60 |
S |
L |
-0.5616 |
|
| 61 |
R |
L |
-0.9554 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.8848 |
|
| 64 |
G |
L |
-0.6813 |
|
| 65 |
S |
L |
-0.8268 |
|
| 66 |
G |
L |
-0.9839 |
|
| 67 |
S |
L |
-0.5970 |
|
| 68 |
G |
L |
-0.3540 |
|
| 69 |
T |
L |
-0.9309 |
|
| 70 |
D |
L |
-2.0934 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7432 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
S |
L |
-0.8886 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
N |
L |
-2.6582 |
|
| 77 |
T |
L |
-2.2676 |
|
| 78 |
V |
L |
0.0000 |
|
| 79 |
E |
L |
-2.8434 |
|
| 80 |
S |
L |
-2.5741 |
|
| 81 |
E |
L |
-3.1142 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
I |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
D |
L |
-1.0496 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.1522 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
S |
L |
0.4571 |
|
| 92 |
H |
L |
-0.3782 |
|
| 93 |
S |
L |
0.0488 |
|
| 94 |
W |
L |
0.7835 |
|
| 95 |
P |
L |
0.4189 |
|
| 96 |
F |
L |
1.2948 |
|
| 97 |
T |
L |
1.2582 |
|
| 98 |
F |
L |
2.1102 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
S |
L |
0.2473 |
|
| 101 |
G |
L |
0.1323 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
N |
L |
-0.1840 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
0.0000 |
|
| 106 |
V |
L |
0.0000 |
|
| 107 |
K |
L |
-1.2661 |
|
| 108 |
R |
L |
-1.0816 |
|
| 109 |
T |
L |
-0.1390 |
|
| 110 |
V |
L |
0.4757 |
|
| 111 |
A |
L |
-0.1086 |
|
| 112 |
A |
L |
-0.1847 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1213 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.1183 |
|
| 117 |
I |
L |
1.1637 |
|
| 118 |
F |
L |
1.5132 |
|
| 119 |
P |
L |
-0.0952 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.7440 |
|
| 122 |
D |
L |
-3.3329 |
|
| 123 |
E |
L |
-3.4592 |
|
| 124 |
Q |
L |
-2.5597 |
|
| 125 |
L |
L |
-2.5961 |
|
| 126 |
K |
L |
-3.0497 |
|
| 127 |
S |
L |
-1.9048 |
|
| 128 |
G |
L |
-1.5562 |
|
| 129 |
T |
L |
-1.4432 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0461 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7019 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.4472 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.3410 |
|
| 138 |
N |
L |
-1.1678 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.3162 |
|
| 142 |
R |
L |
-2.0426 |
|
| 143 |
E |
L |
-2.7697 |
|
| 144 |
A |
L |
-2.0539 |
|
| 145 |
K |
L |
-2.4092 |
|
| 146 |
V |
L |
-1.0441 |
|
| 147 |
Q |
L |
-0.6106 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5180 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.8359 |
|
| 152 |
N |
L |
-1.4961 |
|
| 153 |
A |
L |
-0.2929 |
|
| 154 |
L |
L |
0.6805 |
|
| 155 |
Q |
L |
-0.1850 |
|
| 156 |
S |
L |
-0.4071 |
|
| 157 |
G |
L |
-0.9746 |
|
| 158 |
N |
L |
-0.8911 |
|
| 159 |
S |
L |
-1.3673 |
|
| 160 |
Q |
L |
-2.2712 |
|
| 161 |
E |
L |
-2.2048 |
|
| 162 |
S |
L |
-0.7210 |
|
| 163 |
V |
L |
0.5741 |
|
| 164 |
T |
L |
-0.5385 |
|
| 165 |
E |
L |
-2.1808 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.4995 |
|
| 168 |
S |
L |
-2.9005 |
|
| 169 |
K |
L |
-2.9094 |
|
| 170 |
D |
L |
-2.1541 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.4737 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.2151 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6265 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.3408 |
|
| 181 |
L |
L |
-0.7488 |
|
| 182 |
S |
L |
-1.1680 |
|
| 183 |
K |
L |
-2.1282 |
|
| 184 |
A |
L |
-2.0648 |
|
| 185 |
D |
L |
-3.0208 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.3612 |
|
| 188 |
K |
L |
-3.6609 |
|
| 189 |
H |
L |
-3.1297 |
|
| 190 |
K |
L |
-3.0383 |
|
| 191 |
V |
L |
-1.4807 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
-0.6970 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.7885 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.0951 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.6909 |
|
| 200 |
G |
L |
-0.4839 |
|
| 201 |
L |
L |
-0.1854 |
|
| 202 |
S |
L |
-0.4255 |
|
| 203 |
S |
L |
-0.3651 |
|
| 204 |
P |
L |
-0.5641 |
|
| 205 |
V |
L |
0.1404 |
|
| 206 |
T |
L |
-0.4113 |
|
| 207 |
K |
L |
-0.5005 |
|
| 208 |
S |
L |
-0.4241 |
|
| 209 |
F |
L |
-0.6252 |
|
| 210 |
N |
L |
-1.5936 |
|
| 211 |
R |
L |
-2.2939 |
|
| 212 |
G |
L |
-2.0750 |
|
| 213 |
E |
L |
-2.0626 |
|
| 214 |
C |
L |
-0.3219 |
|