| Chain sequence(s) |
A: ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNRAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ B: ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNRAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | A | A | -1.5321 | |
| 2 | T | A | -1.3236 | |
| 3 | K | A | -1.4398 | |
| 4 | A | A | 0.0000 | |
| 5 | V | A | 0.0000 | |
| 6 | C | A | 0.0000 | |
| 7 | V | A | 0.0144 | |
| 8 | L | A | 0.0000 | |
| 9 | K | A | -2.2913 | |
| 10 | G | A | -2.2222 | |
| 11 | D | A | -2.5284 | |
| 12 | G | A | -1.8355 | |
| 13 | P | A | -1.6334 | |
| 14 | V | A | 0.0000 | |
| 15 | Q | A | -2.2201 | |
| 16 | G | A | -0.9374 | |
| 17 | I | A | 0.3809 | |
| 18 | I | A | 0.0000 | |
| 19 | N | A | -0.3452 | |
| 20 | F | A | 0.0000 | |
| 21 | E | A | -1.8674 | |
| 22 | Q | A | 0.0000 | |
| 23 | K | A | -2.9207 | |
| 24 | E | A | -2.7748 | |
| 25 | S | A | -2.0407 | |
| 26 | N | A | -2.1673 | |
| 27 | G | A | -1.8210 | |
| 28 | P | A | -1.8060 | |
| 29 | V | A | 0.0000 | |
| 30 | K | A | -2.4788 | |
| 31 | V | A | 0.0000 | |
| 32 | W | A | -0.6420 | |
| 33 | G | A | -0.2431 | |
| 34 | S | A | -0.8651 | |
| 35 | I | A | 0.0000 | |
| 36 | K | A | -2.0090 | |
| 37 | G | A | -1.6014 | |
| 38 | L | A | 0.0000 | |
| 39 | T | A | -2.1420 | |
| 40 | E | A | -3.0796 | |
| 41 | G | A | -1.2209 | |
| 42 | L | A | 0.1926 | |
| 43 | H | A | 0.0000 | |
| 44 | G | A | 0.0000 | |
| 45 | F | A | 0.0000 | |
| 46 | H | A | 0.0000 | |
| 47 | V | A | 0.0000 | |
| 48 | H | A | 0.0000 | |
| 49 | E | A | 0.0000 | |
| 50 | F | A | -0.8738 | |
| 51 | G | A | 0.0000 | |
| 52 | D | A | 0.0000 | |
| 53 | N | A | -2.0088 | |
| 54 | R | A | -2.6594 | |
| 55 | A | A | -1.3940 | |
| 56 | G | A | -1.2010 | |
| 57 | C | A | -0.6962 | |
| 58 | T | A | -0.3676 | |
| 59 | S | A | -0.7857 | |
| 60 | A | A | 0.0000 | |
| 61 | G | A | -0.8898 | |
| 62 | P | A | -0.5963 | |
| 63 | H | A | 0.0000 | |
| 64 | F | A | 0.0000 | |
| 65 | N | A | -0.5303 | |
| 66 | P | A | -0.3179 | |
| 67 | L | A | 0.3953 | |
| 68 | S | A | -0.8591 | |
| 69 | R | A | -2.8531 | |
| 70 | K | A | -3.6496 | |
| 71 | H | A | 0.0000 | |
| 72 | G | A | 0.0000 | |
| 73 | G | A | 0.0000 | |
| 74 | P | A | -1.7187 | |
| 75 | K | A | -2.5419 | |
| 76 | D | A | -2.6395 | |
| 77 | E | A | -3.4937 | |
| 78 | E | A | -3.8217 | |
| 79 | R | A | 0.0000 | |
| 80 | H | A | 0.0000 | |
| 81 | V | A | 0.0000 | |
| 82 | G | A | 0.0000 | |
| 83 | D | A | 0.0000 | |
| 84 | L | A | 0.0000 | |
| 85 | G | A | 0.0000 | |
| 86 | N | A | -0.1581 | |
| 87 | V | A | 0.0000 | |
| 88 | T | A | -0.6045 | |
| 89 | A | A | 0.0000 | |
| 90 | D | A | -3.2336 | |
| 91 | K | A | -3.6489 | |
| 92 | D | A | -3.3944 | |
| 93 | G | A | 0.0000 | |
| 94 | V | A | -1.9980 | |
| 95 | A | A | 0.0000 | |
| 96 | D | A | -2.0509 | |
| 97 | V | A | 0.0000 | |
| 98 | S | A | -1.0054 | |
| 99 | I | A | -0.9788 | |
| 100 | E | A | -2.3501 | |
| 101 | D | A | -1.4633 | |
| 102 | S | A | -0.8679 | |
| 103 | V | A | -0.2253 | |
| 104 | I | A | 0.0000 | |
| 105 | S | A | -0.8486 | |
| 106 | L | A | 0.0000 | |
| 107 | S | A | -1.0547 | |
| 108 | G | A | -1.6397 | |
| 109 | D | A | -2.0177 | |
| 110 | H | A | -0.9937 | |
| 111 | C | A | -0.7652 | |
| 112 | I | A | 0.0000 | |
| 113 | I | A | 0.0000 | |
| 114 | G | A | 0.0000 | |
| 115 | R | A | -0.1481 | |
| 116 | T | A | 0.0000 | |
| 117 | L | A | 0.0000 | |
| 118 | V | A | 0.0000 | |
| 119 | V | A | 0.0000 | |
| 120 | H | A | 0.0000 | |
| 121 | E | A | -2.5801 | |
| 122 | K | A | -2.8193 | |
| 123 | A | A | -1.1543 | |
| 124 | D | A | 0.0000 | |
| 125 | D | A | -1.9135 | |
| 126 | L | A | -1.3154 | |
| 127 | G | A | -2.5436 | |
| 128 | K | A | -2.4921 | |
| 129 | G | A | -2.6539 | |
| 130 | G | A | -2.4318 | |
| 131 | N | A | -3.3355 | |
| 132 | E | A | -3.3904 | |
| 133 | E | A | -3.1742 | |
| 134 | S | A | 0.0000 | |
| 135 | T | A | -3.2578 | |
| 136 | K | A | -3.3726 | |
| 137 | T | A | -2.0112 | |
| 138 | G | A | -2.3876 | |
| 139 | N | A | -2.7792 | |
| 140 | A | A | 0.0000 | |
| 141 | G | A | -1.8514 | |
| 142 | S | A | -1.4531 | |
| 143 | R | A | -1.0799 | |
| 144 | L | A | -1.1114 | |
| 145 | A | A | 0.0000 | |
| 146 | C | A | -0.6788 | |
| 147 | G | A | -0.1741 | |
| 148 | V | A | 0.4023 | |
| 149 | I | A | 0.0000 | |
| 150 | G | A | 0.0000 | |
| 151 | I | A | -0.0118 | |
| 152 | A | A | 0.0000 | |
| 153 | Q | A | -1.5458 | |
| 1 | A | B | -1.6639 | |
| 2 | T | B | -1.5173 | |
| 3 | K | B | -1.6049 | |
| 4 | A | B | 0.0000 | |
| 5 | V | B | 0.0000 | |
| 6 | C | B | 0.0000 | |
| 7 | V | B | 0.0999 | |
| 8 | L | B | 0.0000 | |
| 9 | K | B | -2.2665 | |
| 10 | G | B | -2.3909 | |
| 11 | D | B | -2.5925 | |
| 12 | G | B | -1.9070 | |
| 13 | P | B | -1.7344 | |
| 14 | V | B | 0.0000 | |
| 15 | Q | B | -2.3162 | |
| 16 | G | B | -0.9825 | |
| 17 | I | B | 0.4898 | |
| 18 | I | B | 0.0000 | |
| 19 | N | B | -0.6482 | |
| 20 | F | B | 0.0000 | |
| 21 | E | B | -2.1822 | |
| 22 | Q | B | 0.0000 | |
| 23 | K | B | -3.2491 | |
| 24 | E | B | -3.2186 | |
| 25 | S | B | -2.2190 | |
| 26 | N | B | -2.2194 | |
| 27 | G | B | -2.2187 | |
| 28 | P | B | -1.8665 | |
| 29 | V | B | 0.0000 | |
| 30 | K | B | -2.3235 | |
| 31 | V | B | 0.0000 | |
| 32 | W | B | -0.2894 | |
| 33 | G | B | 0.0888 | |
| 34 | S | B | -0.9156 | |
| 35 | I | B | 0.0000 | |
| 36 | K | B | -2.6244 | |
| 37 | G | B | -1.8736 | |
| 38 | L | B | 0.0000 | |
| 39 | T | B | -2.1777 | |
| 40 | E | B | -3.2015 | |
| 41 | G | B | -1.1779 | |
| 42 | L | B | -0.0298 | |
| 43 | H | B | 0.0000 | |
| 44 | G | B | 0.0000 | |
| 45 | F | B | 0.0000 | |
| 46 | H | B | 0.0000 | |
| 47 | V | B | 0.0000 | |
| 48 | H | B | 0.0000 | |
| 49 | E | B | -0.3874 | |
| 50 | F | B | -0.3089 | |
| 51 | G | B | 0.0000 | |
| 52 | D | B | -0.8623 | |
| 53 | N | B | -1.3365 | |
| 54 | R | B | -2.2944 | |
| 55 | A | B | -1.0868 | |
| 56 | G | B | -0.8091 | |
| 57 | C | B | -0.4687 | |
| 58 | T | B | -0.3780 | |
| 59 | S | B | -0.7284 | |
| 60 | A | B | 0.0000 | |
| 61 | G | B | -0.5332 | |
| 62 | P | B | -0.6855 | |
| 63 | H | B | 0.0000 | |
| 64 | F | B | 0.0000 | |
| 65 | N | B | -0.4018 | |
| 66 | P | B | -0.2502 | |
| 67 | L | B | 0.7127 | |
| 68 | S | B | -0.7282 | |
| 69 | R | B | -2.8511 | |
| 70 | K | B | -3.2297 | |
| 71 | H | B | 0.0000 | |
| 72 | G | B | 0.0000 | |
| 73 | G | B | 0.0000 | |
| 74 | P | B | -1.4418 | |
| 75 | K | B | -2.6820 | |
| 76 | D | B | -2.9857 | |
| 77 | E | B | -3.1842 | |
| 78 | E | B | -3.0790 | |
| 79 | R | B | 0.0000 | |
| 80 | H | B | 0.0000 | |
| 81 | V | B | 0.0000 | |
| 82 | G | B | 0.0000 | |
| 83 | D | B | 0.0000 | |
| 84 | L | B | 0.0000 | |
| 85 | G | B | 0.0000 | |
| 86 | N | B | -0.1665 | |
| 87 | V | B | 0.0000 | |
| 88 | T | B | -0.5927 | |
| 89 | A | B | -2.1136 | |
| 90 | D | B | -3.0868 | |
| 91 | K | B | -3.5685 | |
| 92 | D | B | -3.4715 | |
| 93 | G | B | 0.0000 | |
| 94 | V | B | -2.4318 | |
| 95 | A | B | 0.0000 | |
| 96 | D | B | -2.0035 | |
| 97 | V | B | -0.4709 | |
| 98 | S | B | -0.4689 | |
| 99 | I | B | -0.1260 | |
| 100 | E | B | -1.9102 | |
| 101 | D | B | -1.2411 | |
| 102 | S | B | -0.5875 | |
| 103 | V | B | 0.0595 | |
| 104 | I | B | 0.0000 | |
| 105 | S | B | -1.0669 | |
| 106 | L | B | 0.0000 | |
| 107 | S | B | -0.8921 | |
| 108 | G | B | -1.4979 | |
| 109 | D | B | -2.0310 | |
| 110 | H | B | -1.0281 | |
| 111 | C | B | -0.7887 | |
| 112 | I | B | 0.0000 | |
| 113 | I | B | 0.0000 | |
| 114 | G | B | 0.0000 | |
| 115 | R | B | 0.1730 | |
| 116 | T | B | 0.0000 | |
| 117 | L | B | 0.0000 | |
| 118 | V | B | 0.0000 | |
| 119 | V | B | 0.0000 | |
| 120 | H | B | 0.0000 | |
| 121 | E | B | -2.3285 | |
| 122 | K | B | -2.5924 | |
| 123 | A | B | -1.0225 | |
| 124 | D | B | 0.0000 | |
| 125 | D | B | -1.6227 | |
| 126 | L | B | -0.9128 | |
| 127 | G | B | -2.3375 | |
| 128 | K | B | -2.3133 | |
| 129 | G | B | -2.3229 | |
| 130 | G | B | -2.1398 | |
| 131 | N | B | -2.6863 | |
| 132 | E | B | -3.3457 | |
| 133 | E | B | -3.2159 | |
| 134 | S | B | 0.0000 | |
| 135 | T | B | -3.2114 | |
| 136 | K | B | -3.5363 | |
| 137 | T | B | -2.0334 | |
| 138 | G | B | -1.1382 | |
| 139 | N | B | -2.3502 | |
| 140 | A | B | 0.0000 | |
| 141 | G | B | -1.4404 | |
| 142 | S | B | -1.3064 | |
| 143 | R | B | -1.0779 | |
| 144 | L | B | -1.3919 | |
| 145 | A | B | 0.0000 | |
| 146 | C | B | -0.7159 | |
| 147 | G | B | 0.0000 | |
| 148 | V | B | 0.6609 | |
| 149 | I | B | 0.0000 | |
| 150 | G | B | 0.0000 | |
| 151 | I | B | -0.3136 | |
| 152 | A | B | 0.0000 | |
| 153 | Q | B | -1.6688 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine