Project name: 6bi2:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSSCCAASGFNNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCCSSRWGGDGFYAMDYWGQGTLVTVSSASSTKGPSVFPLAPSSKSTSGGTAALGCCLVKDYFPEPVVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICCNVNHKPSNTKVDKKVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9862
• Maximal score value: 2.4336
• Average score: -0.6004
• Total score value: -133.2861

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.0980
2	V	H	-1.4041
3	Q	H	-1.0165
4	L	H	0.0000
5	V	H	1.2148
6	E	H	0.0000
7	S	H	-0.3591
8	G	H	-0.9224
9	G	H	-0.4561
10	G	H	0.0551
11	L	H	0.1916
12	V	H	-0.4789
13	Q	H	-1.4498
14	P	H	-1.5467
15	G	H	-1.3268
16	G	H	-1.0178
17	S	H	-1.0542
18	L	H	-1.0507
19	R	H	-2.0212
20	L	H	0.0000
21	S	H	-0.3355
22	C	H	0.0000
23	A	H	0.0495
24	A	H	0.0000
25	S	H	-0.8191
26	G	H	-1.3422
27	F	H	-1.2891
28	N	H	-2.0209
29	I	H	0.0000
30	K	H	-2.5061
31	D	H	-2.7352
32	T	H	0.0000
33	Y	H	0.0122
34	I	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.4976
40	A	H	-1.0832
41	P	H	-1.0457
42	G	H	-1.4236
43	K	H	-2.0974
44	G	H	-0.9771
45	L	H	0.4935
46	E	H	-0.3480
47	W	H	0.1817
48	V	H	0.0000
49	A	H	0.0000
50	R	H	-0.7683
51	I	H	0.0000
52	Y	H	-0.3739
53	P	H	-1.0009
54	T	H	-1.1471
55	N	H	-0.9438
56	G	H	-0.3406
57	Y	H	0.4779
58	T	H	-0.5261
59	R	H	-2.0454
60	Y	H	-1.8373
61	A	H	-1.7793
62	D	H	-2.6784
63	S	H	-1.6951
64	V	H	0.0000
65	K	H	-2.8808
66	G	H	-1.7725
67	R	H	-1.5135
68	F	H	0.0000
69	T	H	-1.0668
70	I	H	0.0000
71	S	H	-0.1442
72	A	H	-0.8964
73	D	H	-1.5050
74	T	H	-1.6025
75	S	H	-1.5599
76	K	H	-2.2251
77	N	H	-1.6948
78	T	H	-0.8387
79	A	H	0.0000
80	Y	H	-0.5033
81	L	H	0.0000
82	Q	H	-1.1024
83	M	H	0.0000
84	N	H	-1.2998
85	S	H	-1.1365
86	L	H	0.0000
87	R	H	-2.1654
88	A	H	-1.6486
89	E	H	-2.2164
90	D	H	0.0000
91	T	H	-0.6507
92	A	H	0.0000
93	V	H	0.4428
94	Y	H	0.0000
95	Y	H	0.5005
96	C	H	0.0000
97	S	H	0.0000
98	R	H	0.1493
99	W	H	0.3703
100	G	H	-0.0417
101	G	H	-0.6401
102	D	H	-1.6824
103	G	H	-0.3573
104	F	H	1.1236
105	Y	H	1.5570
106	A	H	0.8984
107	M	H	0.5122
108	D	H	-0.2121
109	Y	H	-0.1583
110	W	H	0.2701
111	G	H	0.0441
112	Q	H	-0.7233
113	G	H	-0.1052
114	T	H	0.0829
115	L	H	0.2575
116	V	H	0.0000
117	T	H	-0.3173
118	V	H	0.0000
119	S	H	-0.8367
120	S	H	-0.6373
121	A	H	-0.4133
122	S	H	-0.5403
123	T	H	-0.7157
124	K	H	-1.1718
125	G	H	-1.4673
126	P	H	0.0000
127	S	H	-0.1069
128	V	H	0.0000
129	F	H	1.0490
130	P	H	-0.0024
131	L	H	0.4120
132	A	H	-0.8362
133	P	H	0.0000
134	S	H	-1.2331
135	S	H	-1.4566
136	K	H	-1.9233
137	S	H	-1.2047
138	T	H	-0.9600
139	S	H	-0.9170
140	G	H	-0.8185
141	G	H	-0.6397
142	T	H	-0.4482
143	A	H	0.0000
144	A	H	0.1189
145	L	H	0.0000
146	G	H	0.0000
147	C	H	0.0000
148	L	H	0.7001
149	V	H	0.0000
150	K	H	-0.2106
151	D	H	-0.5994
152	Y	H	0.0000
153	F	H	0.0000
154	P	H	0.0000
155	E	H	-0.5186
156	P	H	-0.8691
157	V	H	-0.8999
158	T	H	-0.7899
159	V	H	-0.3452
160	S	H	-0.5976
161	W	H	0.0000
162	N	H	-0.7863
163	S	H	-0.6753
164	G	H	-0.5796
165	A	H	-0.2521
166	L	H	-0.0541
167	T	H	-0.3573
168	S	H	-0.4108
169	G	H	-0.5189
170	V	H	-0.1581
171	H	H	-0.6092
172	T	H	0.0474
173	F	H	0.8955
174	P	H	0.6673
175	A	H	1.2141
176	V	H	2.4336
177	L	H	1.9758
178	Q	H	0.6503
179	S	H	0.0775
180	S	H	-0.2197
181	G	H	0.2191
182	L	H	0.3067
183	Y	H	0.7744
184	S	H	0.0000
185	L	H	0.0000
186	S	H	0.6348
187	S	H	0.0000
188	V	H	0.3552
189	V	H	0.0000
190	T	H	-0.2350
191	V	H	0.0000
192	P	H	-0.6082
193	S	H	-0.7689
194	S	H	-0.6955
195	S	H	-0.6211
196	L	H	-0.8121
197	G	H	-1.2771
198	T	H	-0.9180
199	Q	H	-1.2378
200	T	H	-1.1479
201	Y	H	0.0000
202	I	H	-1.3942
203	C	H	0.0000
204	N	H	-1.7151
205	V	H	0.0000
206	N	H	-2.5449
207	H	H	0.0000
208	K	H	-2.9111
209	P	H	-1.6448
210	S	H	-1.8825
211	N	H	-2.6930
212	T	H	-2.2454
213	K	H	-2.9862
214	V	H	-1.8671
215	D	H	-2.7791
216	K	H	-2.2066
217	K	H	-2.5332
218	V	H	0.0000
219	E	H	-2.9268
220	P	H	-1.9941
221	K	H	-2.4061
222	S	H	-1.3501