Project name: 3eyv

Chain sequence(s)	A: DIQMTQSPSSLSASVGDRVTITCRSSQRIVHSNGNTYLEWYQQTPGKAPKLLIYKVSNRFSGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCFQGSHVPFTFGQGTKLQITRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNREVQLVESGGGVVQPGRSLRLSCSTSGFTFSDYYMYWVRQAPGKGLEWVAYMSNVGAITDYPDTVKGRFTISRDNSKNTLFLQMDSLRPEDTGVYFCARGTRDGSWFAYWGQGTPVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPQPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.492
• Maximal score value: 2.1155
• Average score: -0.7791
• Total score value: -337.3313

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-1.7725
2	I	A	-1.4904
3	Q	A	-1.9599
4	M	A	0.0000
5	T	A	-1.3664
6	Q	A	0.0000
7	S	A	-0.9194
8	P	A	-0.6483
9	S	A	-0.8659
10	S	A	-0.6849
11	L	A	-0.2790
12	S	A	-0.4144
13	A	A	-0.5806
14	S	A	-0.5225
15	V	A	0.2161
16	G	A	-1.1208
17	D	A	-2.5504
18	R	A	-2.7160
19	V	A	0.0000
20	T	A	-0.4950
21	I	A	0.0000
22	T	A	-0.7284
23	C	A	0.0000
24	R	A	-2.8027
25	S	A	-2.2878
26	S	A	-2.1800
27	Q	A	-2.6793
28	R	A	-2.7924
29	I	A	0.0000
30	V	A	-0.8971
31	H	A	-1.1593
32	S	A	-1.1197
33	N	A	-1.7330
34	G	A	-1.3140
35	N	A	-1.0875
36	T	A	-0.8159
37	Y	A	-0.4200
38	L	A	0.0000
39	E	A	0.0000
40	W	A	0.0000
41	Y	A	0.0000
42	Q	A	0.0000
43	Q	A	-1.0818
44	T	A	-1.1768
45	P	A	-1.2220
46	G	A	-1.4528
47	K	A	-2.3116
48	A	A	-1.5126
49	P	A	0.0000
50	K	A	-1.4450
51	L	A	0.0000
52	L	A	0.0000
53	I	A	0.0000
54	Y	A	-0.5769
55	K	A	-1.2292
56	V	A	-0.7315
57	S	A	-1.0522
58	N	A	-1.5556
59	R	A	-1.5475
60	F	A	-0.6083
61	S	A	-0.5106
62	G	A	-0.5724
63	V	A	-0.5276
64	P	A	-0.5360
65	S	A	-0.6647
66	R	A	-1.0497
67	F	A	0.0000
68	S	A	-0.6765
69	G	A	-0.6367
70	S	A	-0.7178
71	G	A	-0.9763
72	S	A	-0.9895
73	G	A	0.0000
74	T	A	-2.0338
75	D	A	-2.1346
76	F	A	0.0000
77	T	A	-0.6884
78	F	A	0.0000
79	T	A	-0.5827
80	I	A	0.0000
81	S	A	-1.6322
82	S	A	-1.5767
83	L	A	0.0000
84	Q	A	-1.3538
85	P	A	-1.7513
86	E	A	-2.6297
87	D	A	0.0000
88	I	A	0.0000
89	A	A	0.0000
90	T	A	-0.7502
91	Y	A	0.0000
92	Y	A	0.0000
93	C	A	0.0000
94	F	A	0.0000
95	Q	A	0.0000
96	G	A	0.0000
97	S	A	-0.2233
98	H	A	0.3861
99	V	A	1.3121
100	P	A	0.2038
101	F	A	0.3510
102	T	A	-0.1741
103	F	A	-0.3889
104	G	A	0.0000
105	Q	A	-1.5859
106	G	A	-1.2948
107	T	A	0.0000
108	K	A	-1.1131
109	L	A	0.0000
110	Q	A	-0.9381
111	I	A	0.0000
112	T	A	-0.1427
113	R	A	-0.5312
114	T	A	-0.4311
115	V	A	0.0000
116	A	A	-0.6402
117	A	A	-0.4777
118	P	A	0.0000
119	S	A	-0.6329
120	V	A	0.0000
121	F	A	0.0000
122	I	A	0.0000
123	F	A	0.0000
124	P	A	-0.6104
125	P	A	-0.7621
126	S	A	-1.8553
127	D	A	-3.2093
128	E	A	-3.4594
129	Q	A	0.0000
130	L	A	0.0000
131	K	A	-3.1367
132	S	A	-1.8720
133	G	A	-1.5439
134	T	A	-1.2460
135	A	A	0.0000
136	S	A	0.0000
137	V	A	0.0000
138	V	A	0.0000
139	C	A	0.0000
140	L	A	0.0000
141	L	A	0.0000
142	N	A	0.0000
143	N	A	-1.2612
144	F	A	0.0000
145	Y	A	-1.4346
146	P	A	-1.7545
147	R	A	-3.2140
148	E	A	-3.2628
149	A	A	-2.4480
150	K	A	-2.7282
151	V	A	-1.3160
152	Q	A	-1.2536
153	W	A	0.0000
154	K	A	-1.1635
155	V	A	0.0000
156	D	A	-2.8922
157	N	A	-2.1349
158	A	A	-0.8207
159	L	A	-0.0909
160	Q	A	-0.6539
161	S	A	-0.6127
162	G	A	-0.8757
163	N	A	-0.8248
164	S	A	-1.1514
165	Q	A	-1.3427
166	E	A	-2.2749
167	S	A	-1.2022
168	V	A	-1.0438
169	T	A	-0.9813
170	E	A	-1.7904
171	Q	A	0.0000
172	D	A	-2.1069
173	S	A	-2.4062
174	K	A	-2.8435
175	D	A	-2.1705
176	S	A	0.0000
177	T	A	0.0000
178	Y	A	-1.3610
179	S	A	-0.9589
180	L	A	0.0000
181	S	A	0.0000
182	S	A	0.0000
183	T	A	-0.6753
184	L	A	0.0000
185	T	A	-0.2489
186	L	A	-0.6092
187	S	A	-1.0150
188	K	A	-1.8984
189	A	A	-1.6187
190	D	A	-1.9868
191	Y	A	-2.0998
192	E	A	-3.3010
193	K	A	-3.4920
194	H	A	-3.1998
195	K	A	-3.2711
196	V	A	-2.0742
197	Y	A	0.0000
198	A	A	0.0000
199	C	A	0.0000
200	E	A	-1.0819
201	V	A	0.0000
202	T	A	-1.1729
203	H	A	0.0000
204	Q	A	-1.8543
205	G	A	-0.7889
206	L	A	-0.3253
207	S	A	-0.3984
208	S	A	-0.3813
209	P	A	-0.4709
210	V	A	-0.0567
211	T	A	-0.9287
212	K	A	-1.9554
213	S	A	-1.4597
214	F	A	0.0000
215	N	A	-1.7917
1	E	A	-1.9166
2	V	A	-1.0091
3	Q	A	-1.0985
4	L	A	0.0000
5	V	A	0.2773
6	E	A	0.0000
7	S	A	-0.6676
8	G	A	-1.0178
9	G	A	-0.7498
10	G	A	-0.4917
11	V	A	-0.0703
12	V	A	-1.0825
13	Q	A	-2.1922
14	P	A	-2.3282
15	G	A	-2.4898
16	R	A	-3.1113
17	S	A	-2.3498
18	L	A	-1.6469
19	R	A	-2.3931
20	L	A	0.0000
21	S	A	-0.7228
22	C	A	0.0000
23	S	A	-0.5905
24	T	A	0.0000
25	S	A	-0.9648
26	G	A	-1.0244
27	F	A	-0.6502
28	T	A	-0.8468
29	F	A	0.0000
30	S	A	-0.8681
31	D	A	-1.7384
32	Y	A	-0.6790
33	Y	A	-0.2563
34	M	A	0.0000
35	Y	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	0.0000
39	Q	A	-0.8259
40	A	A	-1.1913
41	P	A	-1.0529
42	G	A	-1.4885
43	K	A	-2.4249
44	G	A	-1.7174
45	L	A	0.0000
46	E	A	-1.0499
47	W	A	0.0000
48	V	A	0.0000
49	A	A	0.0000
50	Y	A	0.3993
51	M	A	0.0000
52	S	A	0.5959
53	N	A	0.1108
54	V	A	1.5664
55	G	A	0.9321
56	A	A	1.1913
57	I	A	2.1155
58	T	A	0.7311
59	D	A	0.1103
60	Y	A	-0.7960
61	P	A	-1.1209
62	D	A	-2.3355
63	T	A	-1.6257
64	V	A	0.0000
65	K	A	-2.2170
66	G	A	-1.6787
67	R	A	-1.8183
68	F	A	0.0000
69	T	A	-1.1448
70	I	A	0.0000
71	S	A	-0.4070
72	R	A	-1.5317
73	D	A	-2.5490
74	N	A	-2.7822
75	S	A	-2.2181
76	K	A	-2.8516
77	N	A	-2.4189
78	T	A	0.0000
79	L	A	0.0000
80	F	A	0.0000
81	L	A	0.0000
82	Q	A	-1.8997
83	M	A	0.0000
84	D	A	-2.8845
85	S	A	-2.1726
86	L	A	0.0000
87	R	A	-3.3888
88	P	A	-2.2484
89	E	A	-2.5722
90	D	A	0.0000
91	T	A	-0.9500
92	G	A	0.0000
93	V	A	-0.0412
94	Y	A	0.0000
95	F	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0114
99	G	A	0.0000
100	T	A	-1.5124
101	R	A	-2.8944
102	D	A	-2.7686
103	G	A	-1.5394
104	S	A	0.0000
105	W	A	-0.2811
106	F	A	0.0000
107	A	A	0.0160
108	Y	A	0.0524
109	W	A	0.0000
110	G	A	-0.4928
111	Q	A	-1.1718
112	G	A	0.0000
113	T	A	0.0000
114	P	A	0.0000
115	V	A	0.0000
116	T	A	-0.5967
117	V	A	0.0000
118	S	A	-0.8593
119	S	A	-0.6736
120	A	A	-0.4650
121	S	A	-0.5211
122	T	A	-0.6606
123	K	A	-1.2215
124	G	A	-1.2272
125	P	A	-0.5998
126	S	A	-0.3165
127	V	A	0.0000
128	F	A	0.0000
129	P	A	-1.3018
130	L	A	0.0000
131	A	A	-0.8174
132	P	A	-0.5703
133	S	A	-0.6050
134	S	A	-0.6213
135	K	A	-1.2540
136	S	A	0.0000
137	T	A	-0.7370
138	S	A	-0.8825
139	G	A	-0.8334
140	G	A	-0.8307
141	T	A	-0.5273
142	A	A	0.0000
143	A	A	0.0000
144	L	A	0.0000
145	G	A	0.0000
146	C	A	0.0000
147	L	A	0.0000
148	V	A	0.0000
149	K	A	0.0000
150	D	A	-0.4166
151	Y	A	0.0000
152	F	A	-0.1504
153	P	A	0.0000
154	Q	A	-0.3808
155	P	A	-0.4653
156	V	A	-0.2488
157	T	A	-0.4986
158	V	A	0.0000
159	S	A	-0.4977
160	W	A	0.0000
161	N	A	-0.6848
162	S	A	-0.6438
163	G	A	-0.4894
164	A	A	-0.1028
165	L	A	0.1163
166	T	A	-0.0749
167	S	A	-0.3988
168	G	A	-0.2057
169	V	A	0.0746
170	H	A	-0.3922
171	T	A	-0.2545
172	F	A	0.0000
173	P	A	-0.5110
174	A	A	-0.0360
175	V	A	0.2977
176	L	A	0.9828
177	Q	A	0.0996
178	S	A	-0.1930
179	S	A	-0.3126
180	G	A	-0.1439
181	L	A	0.1179
182	Y	A	0.3978
183	S	A	0.0000
184	L	A	0.0000
185	S	A	0.0000
186	S	A	0.0000
187	V	A	0.0000
188	V	A	0.0000
189	T	A	-0.1081
190	V	A	0.0021
191	P	A	-0.4218
192	S	A	-0.5042
193	S	A	-0.3609
194	S	A	-0.3229
195	L	A	-0.4522
196	G	A	-1.1097
197	T	A	-1.0058
198	Q	A	-1.5510
199	T	A	-1.5451
200	Y	A	0.0000
201	I	A	-1.4680
202	C	A	0.0000
203	N	A	-1.6739
204	V	A	0.0000
205	N	A	-1.5890
206	H	A	0.0000
207	K	A	-1.7299
208	P	A	0.0000
209	S	A	-1.4372
210	N	A	-2.1923
211	T	A	-1.7952
212	K	A	-2.5196
213	V	A	-1.6836
214	D	A	-2.7780
215	K	A	-2.4957
216	K	A	-2.7732
217	V	A	0.0000
218	E	A	-2.5377