Project name: 5ba4650b9fa6e4e

Chain sequence(s)	H: QVQLQESGPGLVQPSETLSLTCTVSGGSVSSGDTYITWIRQSPGQGLEWIGHIYYSGNTNYNPSLRSRLTISIDTSRTQFSLQLSSVTAADTAVYYCSRDRVTGAFDIWGQGTMVTVSS; L: DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQRPGRAPRLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYFCQHFDHLPLAFGGGTRVEIR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.971
• Maximal score value: 0.9215
• Average score: -0.6554
• Total score value: -148.1263

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5548
2	V	H	-1.2418
3	Q	H	-1.9349
4	L	H	0.0000
5	Q	H	-1.8654
6	E	H	0.0000
7	S	H	-0.6605
8	G	H	-0.5013
9	P	H	-0.1378
11	G	H	0.3187
12	L	H	0.8198
13	V	H	0.0000
14	Q	H	-1.2143
15	P	H	-1.1734
16	S	H	-1.4770
17	E	H	-2.2915
18	T	H	-1.4687
19	L	H	0.0000
20	S	H	-0.8977
21	L	H	0.0000
22	T	H	-0.6326
23	C	H	0.0000
24	T	H	-1.1725
25	V	H	0.0000
26	S	H	-1.4626
27	G	H	-1.2768
28	G	H	-1.0187
29	S	H	-0.8141
30	V	H	0.0000
31	S	H	-0.3769
34	S	H	-0.6036
35	G	H	-0.8699
36	D	H	-1.8458
37	T	H	-0.9723
38	Y	H	-0.0432
39	I	H	0.0000
40	T	H	0.0000
41	W	H	0.0000
42	I	H	0.0000
43	R	H	0.0000
44	Q	H	-0.4704
45	S	H	-0.6575
46	P	H	-0.9371
47	G	H	-1.3059
48	Q	H	-1.7553
49	G	H	-1.2483
50	L	H	0.0000
51	E	H	-0.5837
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	H	H	0.0000
56	I	H	0.0000
57	Y	H	-0.0100
58	Y	H	0.3095
59	S	H	-0.2664
63	G	H	-0.7093
64	N	H	-1.4084
65	T	H	-0.7846
66	N	H	-0.7269
67	Y	H	-0.5160
68	N	H	0.0000
69	P	H	-0.7605
70	S	H	-0.7258
71	L	H	0.0000
72	R	H	-1.6641
74	S	H	-1.1301
75	R	H	-1.1780
76	L	H	0.0000
77	T	H	-0.7350
78	I	H	0.0000
79	S	H	-0.3965
80	I	H	-0.3014
81	D	H	-1.2912
82	T	H	-1.0327
83	S	H	-1.4419
84	R	H	-2.2781
85	T	H	-1.4893
86	Q	H	-1.2965
87	F	H	0.0000
88	S	H	-0.4856
89	L	H	0.0000
90	Q	H	-0.9355
91	L	H	0.0000
92	S	H	-1.1815
93	S	H	-1.2512
94	V	H	0.0000
95	T	H	-0.5934
96	A	H	-0.1294
97	A	H	-0.2004
98	D	H	0.0000
99	T	H	0.2725
100	A	H	0.0000
101	V	H	0.4409
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	S	H	0.0000
106	R	H	0.0000
107	D	H	0.0000
108	R	H	-1.4468
109	V	H	-0.3001
110	T	H	-0.3216
113	G	H	0.0000
114	A	H	0.0000
115	F	H	0.0000
116	D	H	-0.7743
117	I	H	-0.6681
118	W	H	-0.9099
119	G	H	0.0000
120	Q	H	-2.0416
121	G	H	-0.9436
122	T	H	-0.1231
123	M	H	0.9215
124	V	H	0.0000
125	T	H	0.4021
126	V	H	0.0000
127	S	H	-0.2322
128	S	H	-0.4078
1	D	L	-2.2779
2	I	L	0.0000
3	Q	L	-2.0854
4	M	L	0.0000
5	T	L	-1.0409
6	Q	L	0.0000
7	S	L	-0.4747
8	P	L	-0.6011
9	S	L	-0.8583
10	S	L	-1.2215
11	L	L	-0.9714
12	S	L	-1.1478
13	A	L	-1.2362
14	S	L	-0.9865
15	V	L	-0.1704
16	G	L	-0.7393
17	D	L	-1.6504
18	R	L	-2.3014
19	V	L	0.0000
20	T	L	-0.6341
21	I	L	0.0000
22	T	L	-0.7431
23	C	L	0.0000
24	Q	L	-2.1308
25	A	L	0.0000
26	S	L	-2.1431
27	Q	L	-2.9710
28	D	L	-2.9063
29	I	L	0.0000
36	S	L	-1.2687
37	N	L	-0.9572
38	Y	L	-0.1995
39	L	L	0.0000
40	N	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	-1.5135
45	R	L	-2.0014
46	P	L	-1.2923
47	G	L	-1.8426
48	R	L	-2.8440
49	A	L	-1.7786
50	P	L	0.0000
51	R	L	-1.5951
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	-0.3291
56	D	L	-0.7629
57	A	L	0.0000
65	S	L	-0.9332
66	N	L	-0.9938
67	L	L	-0.2442
68	E	L	-0.6228
69	T	L	-0.4055
70	G	L	-0.4610
71	V	L	-0.3168
72	P	L	-0.3136
74	S	L	-0.4072
75	R	L	-0.6741
76	F	L	0.0000
77	S	L	-0.4311
78	G	L	0.0000
79	S	L	-0.9763
80	G	L	-1.2182
83	S	L	-1.3330
84	G	L	-1.8613
85	T	L	-2.3272
86	D	L	-2.7110
87	F	L	0.0000
88	T	L	-0.7525
89	F	L	0.0000
90	T	L	-0.5902
91	I	L	0.0000
92	S	L	-1.2811
93	S	L	-1.0918
94	L	L	0.0000
95	Q	L	-0.8524
96	P	L	-1.1962
97	E	L	-1.8889
98	D	L	0.0000
99	I	L	-0.9492
100	A	L	0.0000
101	T	L	-1.1532
102	Y	L	0.0000
103	F	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	H	L	0.0000
107	F	L	-0.0375
108	D	L	-0.9756
109	H	L	-0.8893
114	L	L	-0.2654
115	P	L	0.0000
116	L	L	0.0000
117	A	L	-0.6096
118	F	L	0.0000
119	G	L	0.0000
120	G	L	-1.1227
121	G	L	-0.8324
122	T	L	0.0000
123	R	L	-2.0937
124	V	L	0.0000
125	E	L	-2.3045
126	I	L	-1.3899
127	R	L	-1.8733