Project name: dtave1

Chain sequence(s)	H: EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSAITWNSGHIDYADSVEGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAKVSYLSTASSLDYWGQGTLVTVSS; L: DIQMTQSPSSLSASVGDRVTITCRASQGIRNYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISSLQPEDVATYYCQRYNRAPYTFGQGTKVEIK
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.0002
• Maximal score value: 1.6809
• Average score: -0.268
• Total score value: -61.1057

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.7838
2	V	H	-0.1682
3	Q	H	-0.8282
4	L	H	0.0000
5	V	H	0.6622
6	E	H	0.0000
7	S	H	-0.2044
8	G	H	-0.3501
9	G	H	-0.0924
11	G	H	0.0727
12	L	H	1.5569
13	V	H	0.3874
14	Q	H	-0.7667
15	P	H	-0.3862
16	G	H	-0.8150
17	R	H	-1.8451
18	S	H	-0.5080
19	L	H	-0.1524
20	R	H	-1.8319
21	L	H	0.0000
22	S	H	-0.0117
23	C	H	0.0000
24	A	H	0.0471
25	A	H	0.0000
26	S	H	-0.1545
27	G	H	-0.4336
28	F	H	0.1831
29	T	H	-0.0229
30	F	H	0.0000
35	D	H	-1.2229
36	D	H	-1.7423
37	Y	H	0.0057
38	A	H	0.0000
39	M	H	0.0000
40	H	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	R	H	0.0000
44	Q	H	-0.1431
45	A	H	-0.0652
46	P	H	-0.3391
47	G	H	-0.8262
48	K	H	-1.8106
49	G	H	-0.4458
50	L	H	0.0000
51	E	H	-0.7014
52	W	H	0.0000
53	V	H	0.0000
54	S	H	0.0000
55	A	H	0.0000
56	I	H	0.0000
57	T	H	0.0000
58	W	H	0.4263
59	N	H	-1.1780
62	S	H	-0.4555
63	G	H	-0.5688
64	H	H	-0.3133
65	I	H	0.8864
66	D	H	-0.0422
67	Y	H	0.2004
68	A	H	-0.2766
69	D	H	-1.8224
70	S	H	-0.5160
71	V	H	0.0000
72	E	H	-1.9059
74	G	H	-0.8625
75	R	H	-0.4158
76	F	H	0.0000
77	T	H	-0.0546
78	I	H	0.0000
79	S	H	-0.1679
80	R	H	-0.2999
81	D	H	-0.4940
82	N	H	-0.4081
83	A	H	-0.3098
84	K	H	-1.7653
85	N	H	-0.7643
86	S	H	-0.0953
87	L	H	0.0000
88	Y	H	0.4415
89	L	H	0.0000
90	Q	H	-0.4583
91	M	H	0.0000
92	N	H	-0.6921
93	S	H	-0.3329
94	L	H	0.0000
95	R	H	-1.0886
96	A	H	-0.4723
97	E	H	-1.8093
98	D	H	0.0000
99	T	H	-0.0171
100	A	H	0.0000
101	V	H	0.4849
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	K	H	0.0000
107	V	H	0.0000
108	S	H	0.0430
109	Y	H	0.6779
110	L	H	1.5844
111	S	H	0.0627
111A	T	H	-0.0332
112	A	H	0.0079
113	S	H	0.0000
114	S	H	-0.0299
115	L	H	0.0000
116	D	H	-0.3855
117	Y	H	0.5021
118	W	H	0.0000
119	G	H	0.0000
120	Q	H	-1.2085
121	G	H	-0.2778
122	T	H	0.2660
123	L	H	1.5674
124	V	H	0.0000
125	T	H	0.1338
126	V	H	0.0000
127	S	H	-0.1609
128	S	H	-0.2355
1	D	L	-1.7894
2	I	L	0.0000
3	Q	L	-1.1983
4	M	L	0.0000
5	T	L	-0.2163
6	Q	L	0.0000
7	S	L	-0.1235
8	P	L	-0.1625
9	S	L	-0.2697
10	S	L	-0.3615
11	L	L	0.3856
12	S	L	-0.5472
13	A	L	0.0000
14	S	L	0.2891
15	V	L	1.6809
16	G	L	-0.2832
17	D	L	-1.1112
18	R	L	-1.9960
19	V	L	0.0000
20	T	L	-0.0727
21	I	L	0.0000
22	T	L	-0.0119
23	C	L	0.0000
24	R	L	-1.6327
25	A	L	0.0000
26	S	L	-0.3523
27	Q	L	-1.2854
28	G	L	-0.5865
29	I	L	0.0000
36	R	L	-2.0002
37	N	L	-0.9917
38	Y	L	0.5119
39	L	L	0.0000
40	A	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	-0.1217
44	Q	L	0.0000
45	K	L	-0.4849
46	P	L	-0.4203
47	G	L	-0.8264
48	K	L	-1.7840
49	A	L	-0.3035
50	P	L	0.0000
51	K	L	-1.7000
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	0.3458
56	A	L	0.1790
57	A	L	0.0000
65	S	L	-0.2287
66	T	L	0.0065
67	L	L	0.4054
68	Q	L	-0.2328
69	S	L	-0.3494
70	G	L	-0.4689
71	V	L	0.0964
72	P	L	-0.1021
74	S	L	-0.2907
75	R	L	-0.3658
76	F	L	0.0000
77	S	L	-0.1596
78	G	L	-0.1576
79	S	L	-0.2650
80	G	L	-0.2995
83	S	L	-0.3650
84	G	L	-0.4740
85	T	L	-0.4259
86	D	L	-1.9522
87	F	L	0.0000
88	T	L	-0.0192
89	L	L	0.0000
90	T	L	-0.0238
91	I	L	0.0000
92	S	L	-0.3517
93	S	L	-0.3819
94	L	L	0.0000
95	Q	L	-0.6430
96	P	L	-0.6250
97	E	L	-1.4641
98	D	L	0.0000
99	V	L	0.3435
100	A	L	0.0000
101	T	L	-0.2479
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	R	L	0.0000
107	Y	L	0.0000
108	N	L	-0.6353
109	R	L	-1.8968
114	A	L	-0.3472
115	P	L	-0.0610
116	Y	L	0.0000
117	T	L	-0.0116
118	F	L	0.0000
119	G	L	0.0000
120	Q	L	-1.1434
121	G	L	0.0000
122	T	L	0.0000
123	K	L	-1.7254
124	V	L	0.0000
125	E	L	-1.4992
126	I	L	1.2464
127	K	L	-1.3795