Project name: 5iop:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSGGTAALGCLVKDYFPEEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8703
• Maximal score value: 2.4455
• Average score: -0.5056
• Total score value: -108.7019

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4869
2	V	B	-0.9027
3	Q	B	-1.6526
4	L	B	0.0000
5	K	B	-2.3503
6	Q	B	-1.4396
7	S	B	-0.9708
8	G	B	-1.2519
9	P	B	-0.5476
10	G	B	-0.4490
11	L	B	-0.0806
12	V	B	-0.8080
13	Q	B	-1.6283
14	P	B	-1.5521
15	S	B	-1.5284
16	Q	B	-1.8383
17	S	B	-1.5384
18	L	B	0.0000
19	S	B	-0.6319
20	I	B	0.0000
21	T	B	-0.6239
22	C	B	0.0000
23	T	B	-1.2372
24	V	B	0.0000
25	S	B	-1.2429
26	G	B	-0.9981
27	F	B	-0.5226
28	S	B	-0.8823
29	L	B	0.0000
30	T	B	-0.9144
31	N	B	-0.8803
32	Y	B	0.4319
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.2649
40	S	B	0.0000
41	P	B	-1.1073
42	G	B	-1.6716
43	K	B	-2.0328
44	G	B	-0.6574
45	L	B	0.7396
46	E	B	0.0672
47	W	B	0.3866
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.5792
53	S	B	-0.6532
54	G	B	-1.2322
55	G	B	-1.5247
56	N	B	-1.9572
57	T	B	-1.5309
58	D	B	-1.5674
59	Y	B	-0.6990
60	N	B	-0.6876
61	T	B	-0.5345
62	P	B	-0.4653
63	F	B	0.0000
64	T	B	-0.6084
65	S	B	-0.6044
66	R	B	-0.9932
67	L	B	0.0000
68	S	B	-1.0797
69	I	B	0.0000
70	N	B	-1.7334
71	K	B	-1.4383
72	D	B	-1.7621
73	N	B	-2.2140
74	S	B	-1.6779
75	K	B	-2.3638
76	S	B	-1.6071
77	Q	B	-1.5768
78	V	B	0.0000
79	F	B	-0.3838
80	F	B	0.0000
81	K	B	-1.4323
82	M	B	0.0000
83	N	B	-1.6895
84	S	B	-1.5156
85	L	B	0.0000
86	Q	B	-2.2241
87	S	B	-1.5917
88	N	B	-2.1133
89	D	B	0.0000
90	T	B	-0.7088
91	A	B	0.0000
92	I	B	0.4934
93	Y	B	0.0000
94	Y	B	-0.1098
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.8107
100	T	B	1.4112
101	Y	B	1.9601
102	Y	B	1.7910
103	D	B	0.8141
104	Y	B	0.7742
105	E	B	-0.0056
106	F	B	0.6281
107	A	B	0.7853
108	Y	B	0.5520
109	W	B	0.0852
110	G	B	0.0000
111	Q	B	-1.5588
112	G	B	-0.7288
113	T	B	0.0000
114	L	B	0.1534
115	V	B	0.0000
116	T	B	-0.3449
117	V	B	0.0000
118	S	B	-0.6103
119	A	B	-0.3933
120	A	B	-0.3203
121	S	B	-0.5400
122	T	B	-0.6192
123	K	B	-1.2893
124	G	B	-1.4138
125	P	B	0.0000
126	S	B	-0.1120
127	V	B	0.0000
128	F	B	0.9522
129	P	B	-0.1098
130	L	B	0.3832
131	A	B	-0.8901
132	P	B	0.0000
133	S	B	-0.7756
139	G	B	-0.7634
140	G	B	-0.8856
141	T	B	-0.6137
142	A	B	-0.3642
143	A	B	0.1036
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.6696
148	V	B	0.0000
149	K	B	-0.2146
150	D	B	-0.6330
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.0997
155	P	B	-0.5312
156	V	B	-0.5415
157	T	B	-0.5253
158	V	B	-0.2446
159	S	B	-0.4395
160	W	B	0.0000
161	N	B	-0.7510
162	S	B	-0.6429
163	G	B	-0.5789
164	A	B	-0.2432
165	L	B	-0.0509
166	T	B	-0.3008
167	S	B	-0.3730
168	G	B	-0.4523
169	V	B	0.0316
170	H	B	-0.3351
171	T	B	0.2922
172	F	B	1.0934
173	P	B	0.7800
174	A	B	1.2986
175	V	B	2.4455
176	L	B	2.0324
177	Q	B	0.6263
178	S	B	0.0565
179	S	B	-0.2318
180	G	B	0.1979
181	L	B	0.2973
182	Y	B	0.8372
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6923
186	S	B	0.0000
187	V	B	0.5100
188	V	B	0.0000
189	T	B	-0.2028
190	V	B	0.0000
191	P	B	-0.5676
192	S	B	-0.6240
193	S	B	-0.6346
194	S	B	-0.6601
195	L	B	-0.8310
196	G	B	-0.9721
197	T	B	-0.7370
198	Q	B	-1.2085
199	T	B	-1.1565
200	Y	B	0.0000
201	I	B	-1.3812
202	C	B	0.0000
203	N	B	-1.4108
204	V	B	0.0000
205	N	B	-1.9063
206	H	B	0.0000
207	K	B	-2.6968
208	P	B	-1.5559
209	S	B	-1.8167
210	N	B	-2.5685
211	T	B	-2.0160
212	K	B	-2.6142
213	V	B	-1.5413
214	D	B	-2.2358
215	K	B	-1.9379
216	R	B	-2.5595
217	V	B	0.0000
218	E	B	-2.8703
219	P	B	-1.8609
220	K	B	-2.2391