Project name: 6e9v 1 cadena
Status: done
submitted: 2018-12-04 15:22:03, status changed: 2018-12-04 15:36:14
Settings
|
Chain sequence(s)
|
Q: PEDELKRVEKLVKEAEMLLMLAKIKGSEKDLEKALRTAEEAAREAKKVLEQAEKEGDPEVALRAVELVVRVAELLLRIAKESGSEEALMTALLVAVVAATLAVRVLVLAAVQGDPEVALRAVELVVRVAELLLRIAKESGSEEALERALRVAEEAARLAKRVLELAQEQGDPVVAIAAVMLVKRVAELLERIARESGSEEAKERAERVREE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-5.4215
-
Maximal score value
-
2.9359
-
Average score
-
-1.4261
-
Total score value
-
-300.9122
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
P |
Q |
-1.9613 |
|
| 2 |
E |
Q |
-3.4129 |
|
| 3 |
D |
Q |
-3.6916 |
|
| 4 |
E |
Q |
-3.9497 |
|
| 5 |
L |
Q |
0.0000 |
|
| 6 |
K |
Q |
-4.3440 |
|
| 7 |
R |
Q |
-4.6764 |
|
| 8 |
V |
Q |
0.0000 |
|
| 9 |
E |
Q |
-4.5523 |
|
| 10 |
K |
Q |
-4.7269 |
|
| 11 |
L |
Q |
0.0000 |
|
| 12 |
V |
Q |
0.0000 |
|
| 13 |
K |
Q |
-3.9464 |
|
| 14 |
E |
Q |
-3.4419 |
|
| 15 |
A |
Q |
0.0000 |
|
| 16 |
E |
Q |
-1.8940 |
|
| 17 |
M |
Q |
-0.9750 |
|
| 18 |
L |
Q |
-0.8998 |
|
| 19 |
L |
Q |
0.0000 |
|
| 20 |
M |
Q |
0.1704 |
|
| 21 |
L |
Q |
0.4374 |
|
| 22 |
A |
Q |
0.0000 |
|
| 23 |
K |
Q |
-1.5649 |
|
| 24 |
I |
Q |
0.5481 |
|
| 25 |
K |
Q |
-1.4982 |
|
| 26 |
G |
Q |
-1.8526 |
|
| 27 |
S |
Q |
-2.3617 |
|
| 28 |
E |
Q |
-3.8730 |
|
| 29 |
K |
Q |
-3.4027 |
|
| 30 |
D |
Q |
-2.7080 |
|
| 31 |
L |
Q |
-2.6957 |
|
| 32 |
E |
Q |
-3.1661 |
|
| 33 |
K |
Q |
-3.2006 |
|
| 34 |
A |
Q |
0.0000 |
|
| 35 |
L |
Q |
-2.0730 |
|
| 36 |
R |
Q |
-3.0589 |
|
| 37 |
T |
Q |
-2.7459 |
|
| 38 |
A |
Q |
0.0000 |
|
| 39 |
E |
Q |
-2.7394 |
|
| 40 |
E |
Q |
-2.8659 |
|
| 41 |
A |
Q |
0.0000 |
|
| 42 |
A |
Q |
0.0000 |
|
| 43 |
R |
Q |
-3.4517 |
|
| 44 |
E |
Q |
-3.3579 |
|
| 45 |
A |
Q |
0.0000 |
|
| 46 |
K |
Q |
-2.6950 |
|
| 47 |
K |
Q |
-3.2208 |
|
| 48 |
V |
Q |
0.0000 |
|
| 49 |
L |
Q |
0.0000 |
|
| 50 |
E |
Q |
-2.7412 |
|
| 51 |
Q |
Q |
-3.0137 |
|
| 52 |
A |
Q |
0.0000 |
|
| 53 |
E |
Q |
-2.8155 |
|
| 54 |
K |
Q |
-3.5221 |
|
| 55 |
E |
Q |
-3.5581 |
|
| 56 |
G |
Q |
-2.5470 |
|
| 57 |
D |
Q |
-2.5581 |
|
| 58 |
P |
Q |
0.0000 |
|
| 59 |
E |
Q |
-2.4654 |
|
| 60 |
V |
Q |
-2.0813 |
|
| 61 |
A |
Q |
0.0000 |
|
| 62 |
L |
Q |
-1.2811 |
|
| 63 |
R |
Q |
-2.1298 |
|
| 64 |
A |
Q |
0.0000 |
|
| 65 |
V |
Q |
0.0000 |
|
| 66 |
E |
Q |
-1.1165 |
|
| 67 |
L |
Q |
0.0000 |
|
| 68 |
V |
Q |
0.0000 |
|
| 69 |
V |
Q |
0.0000 |
|
| 70 |
R |
Q |
-1.3415 |
|
| 71 |
V |
Q |
0.0000 |
|
| 72 |
A |
Q |
0.0000 |
|
| 73 |
E |
Q |
-1.1908 |
|
| 74 |
L |
Q |
0.0000 |
|
| 75 |
L |
Q |
0.0000 |
|
| 76 |
L |
Q |
0.0000 |
|
| 77 |
R |
Q |
-2.8608 |
|
| 78 |
I |
Q |
0.0000 |
|
| 79 |
A |
Q |
0.0000 |
|
| 80 |
K |
Q |
-3.6186 |
|
| 81 |
E |
Q |
-3.4219 |
|
| 82 |
S |
Q |
-2.8810 |
|
| 83 |
G |
Q |
-2.5484 |
|
| 84 |
S |
Q |
-2.2962 |
|
| 85 |
E |
Q |
-2.9949 |
|
| 86 |
E |
Q |
-2.5511 |
|
| 87 |
A |
Q |
0.0000 |
|
| 88 |
L |
Q |
-1.4553 |
|
| 89 |
M |
Q |
-0.1961 |
|
| 90 |
T |
Q |
0.0151 |
|
| 91 |
A |
Q |
0.0000 |
|
| 92 |
L |
Q |
0.9136 |
|
| 93 |
L |
Q |
1.6837 |
|
| 94 |
V |
Q |
0.6370 |
|
| 95 |
A |
Q |
0.0000 |
|
| 96 |
V |
Q |
0.8082 |
|
| 97 |
V |
Q |
0.9265 |
|
| 98 |
A |
Q |
0.0000 |
|
| 99 |
A |
Q |
0.0000 |
|
| 100 |
T |
Q |
0.1728 |
|
| 101 |
L |
Q |
0.0000 |
|
| 102 |
A |
Q |
0.0000 |
|
| 103 |
V |
Q |
0.3082 |
|
| 104 |
R |
Q |
-0.0892 |
|
| 105 |
V |
Q |
0.0000 |
|
| 106 |
L |
Q |
0.0000 |
|
| 107 |
V |
Q |
0.8614 |
|
| 108 |
L |
Q |
0.0000 |
|
| 109 |
A |
Q |
0.0000 |
|
| 110 |
A |
Q |
0.2236 |
|
| 111 |
V |
Q |
1.2365 |
|
| 112 |
Q |
Q |
-0.6761 |
|
| 113 |
G |
Q |
-0.9683 |
|
| 114 |
D |
Q |
-1.5297 |
|
| 115 |
P |
Q |
-2.2309 |
|
| 116 |
E |
Q |
-2.1712 |
|
| 117 |
V |
Q |
-1.5289 |
|
| 118 |
A |
Q |
0.0000 |
|
| 119 |
L |
Q |
0.0000 |
|
| 120 |
R |
Q |
-1.2115 |
|
| 121 |
A |
Q |
0.0000 |
|
| 122 |
V |
Q |
0.0000 |
|
| 123 |
E |
Q |
-0.9113 |
|
| 124 |
L |
Q |
0.0000 |
|
| 125 |
V |
Q |
0.0000 |
|
| 126 |
V |
Q |
0.0000 |
|
| 127 |
R |
Q |
-1.1990 |
|
| 128 |
V |
Q |
0.0000 |
|
| 129 |
A |
Q |
0.0000 |
|
| 130 |
E |
Q |
-1.2223 |
|
| 131 |
L |
Q |
0.0000 |
|
| 132 |
L |
Q |
0.0000 |
|
| 133 |
L |
Q |
0.0000 |
|
| 134 |
R |
Q |
-2.2977 |
|
| 135 |
I |
Q |
0.0000 |
|
| 136 |
A |
Q |
0.0000 |
|
| 137 |
K |
Q |
-3.0243 |
|
| 138 |
E |
Q |
-2.9293 |
|
| 139 |
S |
Q |
-2.3389 |
|
| 140 |
G |
Q |
-2.2038 |
|
| 141 |
S |
Q |
-2.4479 |
|
| 142 |
E |
Q |
-3.4694 |
|
| 143 |
E |
Q |
-3.5316 |
|
| 144 |
A |
Q |
0.0000 |
|
| 145 |
L |
Q |
-2.8431 |
|
| 146 |
E |
Q |
-3.7105 |
|
| 147 |
R |
Q |
-2.9350 |
|
| 148 |
A |
Q |
0.0000 |
|
| 149 |
L |
Q |
0.0000 |
|
| 150 |
R |
Q |
-2.9181 |
|
| 151 |
V |
Q |
-2.0135 |
|
| 152 |
A |
Q |
0.0000 |
|
| 153 |
E |
Q |
0.0000 |
|
| 154 |
E |
Q |
-2.1933 |
|
| 155 |
A |
Q |
0.0000 |
|
| 156 |
A |
Q |
0.0000 |
|
| 157 |
R |
Q |
-3.1104 |
|
| 158 |
L |
Q |
-2.0040 |
|
| 159 |
A |
Q |
0.0000 |
|
| 160 |
K |
Q |
-2.8321 |
|
| 161 |
R |
Q |
-2.8171 |
|
| 162 |
V |
Q |
0.0000 |
|
| 163 |
L |
Q |
-1.3931 |
|
| 164 |
E |
Q |
-3.1938 |
|
| 165 |
L |
Q |
-2.3525 |
|
| 166 |
A |
Q |
0.0000 |
|
| 167 |
Q |
Q |
-3.0778 |
|
| 168 |
E |
Q |
-3.3408 |
|
| 169 |
Q |
Q |
-2.7110 |
|
| 170 |
G |
Q |
-2.1095 |
|
| 171 |
D |
Q |
-1.2306 |
|
| 172 |
P |
Q |
0.2106 |
|
| 173 |
V |
Q |
1.9091 |
|
| 174 |
V |
Q |
0.0000 |
|
| 175 |
A |
Q |
0.0000 |
|
| 176 |
I |
Q |
2.9359 |
|
| 177 |
A |
Q |
1.5844 |
|
| 178 |
A |
Q |
0.0000 |
|
| 179 |
V |
Q |
0.9826 |
|
| 180 |
M |
Q |
0.5687 |
|
| 181 |
L |
Q |
0.0000 |
|
| 182 |
V |
Q |
0.0000 |
|
| 183 |
K |
Q |
-2.8407 |
|
| 184 |
R |
Q |
-2.9355 |
|
| 185 |
V |
Q |
0.0000 |
|
| 186 |
A |
Q |
0.0000 |
|
| 187 |
E |
Q |
-3.5953 |
|
| 188 |
L |
Q |
-2.2877 |
|
| 189 |
L |
Q |
0.0000 |
|
| 190 |
E |
Q |
-4.5232 |
|
| 191 |
R |
Q |
-4.0355 |
|
| 192 |
I |
Q |
0.0000 |
|
| 193 |
A |
Q |
-3.9071 |
|
| 194 |
R |
Q |
-3.9689 |
|
| 195 |
E |
Q |
-3.4688 |
|
| 196 |
S |
Q |
-2.3731 |
|
| 197 |
G |
Q |
-2.1746 |
|
| 198 |
S |
Q |
-2.6707 |
|
| 199 |
E |
Q |
-2.9935 |
|
| 200 |
E |
Q |
-3.3863 |
|
| 201 |
A |
Q |
0.0000 |
|
| 202 |
K |
Q |
-4.7409 |
|
| 203 |
E |
Q |
-4.6281 |
|
| 204 |
R |
Q |
-3.9118 |
|
| 205 |
A |
Q |
0.0000 |
|
| 206 |
E |
Q |
-5.2690 |
|
| 207 |
R |
Q |
-4.9100 |
|
| 208 |
V |
Q |
0.0000 |
|
| 209 |
R |
Q |
-5.4215 |
|
| 210 |
E |
Q |
-4.6266 |
|
| 211 |
E |
Q |
-4.4191 |
|