Project name: 5n2k:A

Chain sequence(s)	A: QSVLTQPPSVSGAPGQRVTISCSGSRSNIGSNTVKWYQQLPGTAPKLLIYYNDQRPSGVPDRFSGSKSGTSASLAITGLQAEDEADYYCQSYDDRRYYTTHHPPALLFGTGTKVTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1974
• Maximal score value: 1.8543
• Average score: -0.7368
• Total score value: -159.1509

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-0.8177
2	S	A	0.2534
3	V	A	1.4978
4	L	A	0.0000
5	T	A	0.3892
6	Q	A	0.0000
7	P	A	-0.3181
8	P	A	-0.5047
9	S	A	-0.4078
10	V	A	-0.1756
11	S	A	-0.6607
12	G	A	0.0000
13	A	A	-1.0467
14	P	A	-1.5723
15	G	A	-1.8066
16	Q	A	-2.4908
17	R	A	-2.6523
18	V	A	0.0000
19	T	A	-0.5213
20	I	A	0.0000
21	S	A	-0.3465
22	C	A	0.0000
23	S	A	-0.2058
24	G	A	-0.4512
25	S	A	-1.1240
26	R	A	-2.4405
27	S	A	-1.4989
28	N	A	0.0000
29	I	A	0.0000
30	G	A	-1.6681
31	S	A	-1.0601
32	N	A	-0.5881
33	T	A	-0.0451
34	V	A	0.0000
35	K	A	-0.0692
36	W	A	0.0000
37	Y	A	-0.2121
38	Q	A	0.0000
39	Q	A	-0.8107
40	L	A	-0.5743
41	P	A	-0.4562
42	G	A	-0.5542
43	T	A	-0.5290
44	A	A	-0.5028
45	P	A	-0.8955
46	K	A	-1.3347
47	L	A	-0.3996
48	L	A	0.0000
49	I	A	0.0000
50	Y	A	-0.0397
51	Y	A	0.3845
52	N	A	-0.8487
53	D	A	-1.8444
54	Q	A	-1.6392
55	R	A	-1.6909
56	P	A	-0.9569
57	S	A	-0.6858
58	G	A	-0.8618
59	V	A	-1.0256
60	P	A	-1.2750
61	D	A	-2.2529
62	R	A	-1.5426
63	F	A	0.0000
64	S	A	-1.3526
65	G	A	0.0000
66	S	A	-0.9971
67	K	A	-1.0422
68	S	A	-0.7982
69	G	A	-1.1938
70	T	A	-1.2538
71	S	A	-0.9005
72	A	A	0.0000
73	S	A	-0.6292
74	L	A	0.0000
75	A	A	-0.6022
76	I	A	0.0000
77	T	A	-1.7968
78	G	A	-1.6891
79	L	A	0.0000
80	Q	A	-1.8321
81	A	A	-1.4810
82	E	A	-2.1528
83	D	A	0.0000
84	E	A	-1.2027
85	A	A	0.0000
86	D	A	-0.6693
87	Y	A	0.0000
88	Y	A	0.1666
89	C	A	0.0000
90	Q	A	0.0000
91	S	A	0.0000
92	Y	A	0.1875
93	D	A	-0.9782
94	R	A	-1.7887
95	Y	A	0.0615
96	T	A	-0.2896
97	H	A	-0.7373
98	P	A	-0.2299
99	A	A	0.3883
100	L	A	1.7286
101	L	A	0.0000
102	F	A	1.8543
103	G	A	0.0000
104	T	A	0.4823
105	G	A	-0.0893
106	T	A	0.0000
107	K	A	-0.7417
108	V	A	0.0000
109	T	A	0.0000
110	V	A	0.0000
111	L	A	-0.6387
112	G	A	-0.7365
113	Q	A	-1.1198
114	P	A	-1.2416
115	K	A	-2.0344
116	A	A	-1.2563
117	A	A	-0.6544
118	P	A	0.0000
119	S	A	-0.5820
120	V	A	0.0000
121	T	A	0.1348
122	L	A	0.6051
123	F	A	1.5946
124	P	A	0.4503
125	P	A	0.0000
126	S	A	-1.0365
127	S	A	-1.7497
128	E	A	-2.8418
129	E	A	-2.4484
130	L	A	-2.4262
131	Q	A	-2.6289
132	A	A	-2.1903
133	N	A	-2.9423
134	K	A	-3.0778
135	A	A	0.0000
136	T	A	-0.0729
137	L	A	0.0000
138	V	A	0.9159
139	C	A	0.0000
140	L	A	0.8561
141	I	A	0.0000
142	S	A	-0.7055
143	D	A	-1.6501
144	F	A	0.0000
145	Y	A	0.0000
146	P	A	0.0000
147	G	A	-0.9375
148	A	A	-0.1633
149	V	A	0.0258
150	T	A	-0.0333
151	V	A	-0.0249
152	A	A	-0.3352
153	W	A	0.0000
154	K	A	-1.0686
155	A	A	0.0000
156	D	A	-1.4996
157	S	A	-0.9680
158	S	A	-0.8053
159	P	A	-0.8845
160	V	A	-0.8386
161	K	A	-1.5612
162	A	A	-0.8946
163	G	A	-0.6502
164	V	A	-0.5226
165	E	A	-1.3915
166	T	A	-0.6161
167	T	A	-0.5005
168	T	A	-0.1485
169	P	A	-0.5630
170	S	A	-1.2799
171	K	A	-2.6067
172	Q	A	-2.2421
173	S	A	-1.7770
174	N	A	-2.5436
175	N	A	-2.8318
176	K	A	-2.4509
177	Y	A	-1.6541
178	A	A	-0.8897
179	A	A	0.0000
180	S	A	0.0307
181	S	A	0.0000
182	Y	A	0.2467
183	L	A	0.0000
184	S	A	-0.5833
185	L	A	-1.0722
186	T	A	-1.9248
187	P	A	-2.6048
188	E	A	-3.1974
189	Q	A	-2.4906
190	W	A	0.0000
191	K	A	-3.1370
192	S	A	-2.4068
193	H	A	-2.4661
194	R	A	-2.6761
195	S	A	0.0000
196	Y	A	0.0000
197	S	A	0.0000
198	C	A	0.0000
199	Q	A	-1.0029
200	V	A	0.0000
201	T	A	-0.4543
202	H	A	0.0000
203	E	A	-1.2907
204	G	A	-0.9399
205	S	A	-0.7177
206	T	A	-0.5742
207	V	A	-0.7218
208	E	A	-2.0807
209	K	A	-1.7279
210	T	A	-0.9589
211	V	A	0.0000
212	A	A	-1.2398
213	P	A	-1.4873
214	T	A	-1.3567
215	E	A	-1.5204
216	C	A	-0.2029