Project name: Madison Cooper

Chain sequence(s)	A: MRTTVLIVLTCVLSVCAAVTPVQDFSLEKIAGKWYLVGFATNAEWFVTQKDSMKVGTVMFVPTEQGDLHLSYATLNADGTCWRMAHLANKTETPGRFVFHSKTWNNDNDMSIVDVVYDNYALSHTIKTQEGVSDVLVKLYSRTPETTADLQQKFIQYSQTAGIQPENIIVLPKNAECPEIEATPAP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.5756
• Maximal score value: 3.2912
• Average score: -0.4395
• Total score value: -81.7409

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	1.5414
2	R	A	0.2141
3	T	A	1.6939
4	T	A	1.9125
5	V	A	2.5848
6	L	A	2.7394
7	I	A	3.2705
8	V	A	3.2912
9	L	A	3.0723
10	T	A	1.9321
11	C	A	2.5274
12	V	A	2.3972
13	L	A	1.7474
14	S	A	0.0000
15	V	A	0.9227
16	C	A	0.0000
17	A	A	0.3233
18	A	A	0.1190
19	V	A	0.1065
20	T	A	-0.1290
21	P	A	-0.7993
22	V	A	-0.8508
23	Q	A	-2.1237
24	D	A	-2.4077
25	F	A	0.0000
26	S	A	-1.4416
27	L	A	-1.0687
28	E	A	-2.2001
29	K	A	-1.9477
30	I	A	0.0000
31	A	A	-0.3857
32	G	A	-0.2554
33	K	A	-0.2473
34	W	A	0.0000
35	Y	A	0.0000
36	L	A	0.0000
37	V	A	0.0000
38	G	A	0.0000
39	F	A	0.0000
40	A	A	0.0000
41	T	A	0.0000
42	N	A	-1.8035
43	A	A	-0.6294
44	E	A	-1.5775
45	W	A	0.2373
46	F	A	-0.0592
47	V	A	0.0000
48	T	A	-0.5718
49	Q	A	-1.4048
50	K	A	-0.8226
51	D	A	-0.8756
52	S	A	-0.5931
53	M	A	-0.3294
54	K	A	-0.8392
55	V	A	0.0000
56	G	A	0.0000
57	T	A	0.0000
58	V	A	0.0000
59	M	A	0.4523
60	F	A	0.0000
61	V	A	0.9600
62	P	A	-0.4926
63	T	A	-1.1033
64	E	A	-2.2820
65	Q	A	-2.3107
66	G	A	-1.6183
67	D	A	0.0000
68	L	A	0.0000
69	H	A	0.4859
70	L	A	0.6052
71	S	A	0.4149
72	Y	A	0.1976
73	A	A	0.0000
74	T	A	0.0000
75	L	A	-0.7059
76	N	A	-1.5218
77	A	A	-1.3486
78	D	A	-2.2397
79	G	A	-1.5579
80	T	A	-0.9084
81	C	A	-0.7559
82	W	A	0.1217
83	R	A	-0.0589
84	M	A	0.1567
85	A	A	0.1710
86	H	A	0.1832
87	L	A	0.2984
88	A	A	0.0000
89	N	A	-0.9530
90	K	A	-1.5623
91	T	A	-1.5195
92	E	A	-2.1645
93	T	A	-1.3437
94	P	A	-1.6021
95	G	A	-1.3001
96	R	A	-1.2006
97	F	A	0.0000
98	V	A	-0.4841
99	F	A	0.0000
100	H	A	-1.7141
101	S	A	-1.5201
102	K	A	-2.3335
103	T	A	-1.1871
104	W	A	-1.1719
105	N	A	-2.2842
106	N	A	-2.4348
107	D	A	-2.0114
108	N	A	0.0000
109	D	A	0.0000
110	M	A	0.0000
111	S	A	0.0000
112	I	A	0.0000
113	V	A	0.0000
114	D	A	0.1677
115	V	A	0.6475
116	V	A	1.0516
117	Y	A	0.4091
118	D	A	-1.3547
119	N	A	-0.9350
120	Y	A	0.0000
121	A	A	0.0000
122	L	A	0.0000
123	S	A	0.0000
124	H	A	0.0000
125	T	A	0.0000
126	I	A	0.0000
127	K	A	-0.8826
128	T	A	-1.0004
129	Q	A	-1.5512
130	E	A	-2.1405
131	G	A	-0.6455
132	V	A	0.7736
133	S	A	0.0333
134	D	A	-0.2422
135	V	A	0.0000
136	L	A	0.0000
137	V	A	0.0000
138	K	A	0.0000
139	L	A	0.0000
140	Y	A	-0.1580
141	S	A	0.0000
142	R	A	-1.1264
143	T	A	-1.2607
144	P	A	-1.2416
145	E	A	-2.0530
146	T	A	0.0000
147	T	A	-1.2282
148	A	A	-1.4558
149	D	A	-2.2946
150	L	A	-1.3223
151	Q	A	-1.5054
152	Q	A	-2.2113
153	K	A	-2.0581
154	F	A	0.0000
155	I	A	-1.1335
156	Q	A	-1.8919
157	Y	A	0.0000
158	S	A	0.0000
159	Q	A	-1.9332
160	T	A	-0.8498
161	A	A	0.0000
162	G	A	-1.2774
163	I	A	0.0000
164	Q	A	-2.5756
165	P	A	-1.8101
166	E	A	-2.3937
167	N	A	0.0000
168	I	A	0.0000
169	I	A	0.8027
170	V	A	1.0672
171	L	A	0.0000
172	P	A	-1.1782
173	K	A	-1.8944
174	N	A	-1.4951
175	A	A	-1.0755
176	E	A	-1.1520
177	C	A	-0.9058
178	P	A	-1.0947
179	E	A	-1.8786
180	I	A	-0.8076
181	E	A	-0.9312
182	A	A	-0.4207
183	T	A	-0.4069
184	P	A	-0.2638
185	A	A	-0.0949
186	P	A	-0.1873