Project name: 6bi2:L
Status: done
submitted: 2019-03-21 14:55:25, status changed: 2019-03-21 15:07:53
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSSRSGTDFTLTISSLQPEDFATYYCCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEEQLKSSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVVTEQDSKDSTYSLSSTLTLSKAAYEKHKVYACCEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.437
-
Maximal score value
-
2.496
-
Average score
-
-0.7776
-
Total score value
-
-165.6335
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.3031 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-2.0552 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.2220 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.7767 |
|
| 8 |
P |
L |
-0.7303 |
|
| 9 |
S |
L |
-1.0299 |
|
| 10 |
S |
L |
-1.0702 |
|
| 11 |
L |
L |
-0.7366 |
|
| 12 |
S |
L |
-0.8992 |
|
| 13 |
A |
L |
-1.0517 |
|
| 14 |
S |
L |
-0.8267 |
|
| 15 |
V |
L |
0.0633 |
|
| 16 |
G |
L |
-0.7165 |
|
| 17 |
D |
L |
-1.9359 |
|
| 18 |
R |
L |
-2.3546 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6469 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7871 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.9403 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-2.3009 |
|
| 27 |
Q |
L |
-2.8670 |
|
| 28 |
D |
L |
-2.8980 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
N |
L |
-1.9859 |
|
| 31 |
T |
L |
-0.9769 |
|
| 32 |
A |
L |
-0.3909 |
|
| 33 |
V |
L |
0.0000 |
|
| 34 |
A |
L |
0.7161 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.0061 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5842 |
|
| 39 |
K |
L |
-2.0565 |
|
| 40 |
P |
L |
-1.4474 |
|
| 41 |
G |
L |
-1.5127 |
|
| 42 |
K |
L |
-2.4260 |
|
| 43 |
A |
L |
-1.5097 |
|
| 44 |
P |
L |
-1.5047 |
|
| 45 |
K |
L |
-1.7656 |
|
| 46 |
L |
L |
-0.1146 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
1.6905 |
|
| 50 |
S |
L |
0.5095 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
0.9285 |
|
| 53 |
F |
L |
2.4960 |
|
| 54 |
L |
L |
1.9165 |
|
| 55 |
Y |
L |
1.3926 |
|
| 56 |
S |
L |
0.3400 |
|
| 57 |
G |
L |
-0.2986 |
|
| 58 |
V |
L |
0.0000 |
|
| 59 |
P |
L |
-0.2847 |
|
| 60 |
S |
L |
-0.3226 |
|
| 61 |
R |
L |
-0.7104 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
0.2686 |
|
| 64 |
G |
L |
0.1851 |
|
| 65 |
S |
L |
-0.6071 |
|
| 66 |
R |
L |
-1.6103 |
|
| 67 |
S |
L |
-1.3780 |
|
| 68 |
G |
L |
-1.8697 |
|
| 69 |
T |
L |
-2.3727 |
|
| 70 |
D |
L |
-2.1715 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.8155 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6172 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3822 |
|
| 77 |
S |
L |
-1.1295 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.7299 |
|
| 80 |
P |
L |
-1.5376 |
|
| 81 |
E |
L |
-2.1553 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-1.3158 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-1.0627 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0272 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.4162 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
H |
L |
-0.3815 |
|
| 92 |
Y |
L |
0.2556 |
|
| 93 |
T |
L |
-0.1340 |
|
| 94 |
T |
L |
-0.5029 |
|
| 95 |
P |
L |
-0.4708 |
|
| 96 |
P |
L |
-0.3869 |
|
| 97 |
T |
L |
-0.0751 |
|
| 98 |
F |
L |
1.1196 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-1.1057 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-2.0231 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.3203 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.4417 |
|
| 108 |
R |
L |
-0.8685 |
|
| 109 |
T |
L |
-0.2171 |
|
| 110 |
V |
L |
0.0265 |
|
| 111 |
A |
L |
-0.2731 |
|
| 112 |
A |
L |
-0.3123 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1539 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.1837 |
|
| 117 |
I |
L |
1.2028 |
|
| 118 |
F |
L |
1.4036 |
|
| 119 |
P |
L |
0.0110 |
|
| 120 |
P |
L |
-0.7614 |
|
| 121 |
S |
L |
-1.8246 |
|
| 122 |
D |
L |
-3.2366 |
|
| 123 |
E |
L |
-3.4370 |
|
| 124 |
Q |
L |
-2.4784 |
|
| 125 |
L |
L |
-2.5972 |
|
| 126 |
K |
L |
-3.0498 |
|
| 127 |
S |
L |
-1.9242 |
|
| 128 |
G |
L |
-1.3967 |
|
| 129 |
T |
L |
-1.0365 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0034 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7034 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5023 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6331 |
|
| 138 |
N |
L |
-1.3298 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.9200 |
|
| 142 |
R |
L |
-2.9834 |
|
| 143 |
E |
L |
-3.2507 |
|
| 144 |
A |
L |
-2.3696 |
|
| 145 |
K |
L |
-2.1023 |
|
| 146 |
V |
L |
-1.0028 |
|
| 147 |
Q |
L |
-0.5959 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5888 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.7006 |
|
| 152 |
N |
L |
-1.5115 |
|
| 153 |
A |
L |
-0.3011 |
|
| 154 |
L |
L |
0.6080 |
|
| 155 |
Q |
L |
-0.1709 |
|
| 156 |
S |
L |
-0.4422 |
|
| 157 |
G |
L |
-0.9966 |
|
| 158 |
N |
L |
-0.9639 |
|
| 159 |
S |
L |
-1.4329 |
|
| 160 |
Q |
L |
-2.3012 |
|
| 161 |
E |
L |
-2.3439 |
|
| 162 |
S |
L |
-1.3567 |
|
| 163 |
V |
L |
-0.8604 |
|
| 164 |
T |
L |
-1.2935 |
|
| 165 |
E |
L |
-2.2944 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.5083 |
|
| 168 |
S |
L |
-2.3368 |
|
| 169 |
K |
L |
-2.6575 |
|
| 170 |
D |
L |
-2.0102 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-1.0581 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4912 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6198 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.3996 |
|
| 181 |
L |
L |
-0.4142 |
|
| 182 |
S |
L |
-0.7636 |
|
| 183 |
K |
L |
-1.8826 |
|
| 184 |
A |
L |
-1.4014 |
|
| 185 |
A |
L |
-1.4143 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.1465 |
|
| 188 |
K |
L |
-3.1625 |
|
| 189 |
H |
L |
-2.7376 |
|
| 190 |
K |
L |
-3.1216 |
|
| 191 |
V |
L |
-1.3518 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.7522 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.1625 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.6019 |
|
| 200 |
G |
L |
-0.5160 |
|
| 201 |
L |
L |
-0.2759 |
|
| 202 |
S |
L |
-0.4645 |
|
| 203 |
S |
L |
-0.4203 |
|
| 204 |
P |
L |
-0.4978 |
|
| 205 |
V |
L |
0.0987 |
|
| 206 |
T |
L |
-0.2840 |
|
| 207 |
K |
L |
-0.2552 |
|
| 208 |
S |
L |
-0.2813 |
|
| 209 |
F |
L |
-0.7370 |
|
| 210 |
N |
L |
-1.9099 |
|
| 211 |
R |
L |
-2.5020 |
|
| 212 |
G |
L |
-2.1398 |
|
| 213 |
E |
L |
-2.4797 |
|