Project name: 6aru:B
Status: done
submitted: 2019-03-21 14:52:58, status changed: 2019-03-21 15:03:10
Settings
|
Chain sequence(s)
|
B: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYADESIDGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFN
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6901
-
Maximal score value
-
1.9143
-
Average score
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-0.913
-
Total score value
-
-191.7201
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
B |
-1.5216 |
|
| 2 |
I |
B |
0.0000 |
|
| 3 |
L |
B |
0.7723 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
T |
B |
-0.1449 |
|
| 6 |
Q |
B |
-0.1106 |
|
| 7 |
S |
B |
0.1520 |
|
| 8 |
P |
B |
0.8838 |
|
| 9 |
V |
B |
1.9143 |
|
| 10 |
I |
B |
1.4563 |
|
| 11 |
L |
B |
0.5971 |
|
| 12 |
S |
B |
-0.2107 |
|
| 13 |
V |
B |
0.0000 |
|
| 14 |
S |
B |
-1.8802 |
|
| 15 |
P |
B |
-1.9937 |
|
| 16 |
G |
B |
-2.2653 |
|
| 17 |
E |
B |
-2.9993 |
|
| 18 |
R |
B |
-3.2638 |
|
| 19 |
V |
B |
0.0000 |
|
| 20 |
S |
B |
-0.8900 |
|
| 21 |
F |
B |
0.0000 |
|
| 22 |
S |
B |
-0.9610 |
|
| 23 |
C |
B |
0.0000 |
|
| 24 |
R |
B |
-2.3138 |
|
| 25 |
A |
B |
0.0000 |
|
| 26 |
S |
B |
-1.0651 |
|
| 27 |
Q |
B |
-1.9098 |
|
| 28 |
S |
B |
-1.5523 |
|
| 29 |
I |
B |
0.0000 |
|
| 30 |
G |
B |
-0.9920 |
|
| 31 |
T |
B |
-1.2195 |
|
| 32 |
N |
B |
-1.0378 |
|
| 33 |
I |
B |
0.0000 |
|
| 34 |
H |
B |
0.0000 |
|
| 35 |
W |
B |
0.0000 |
|
| 36 |
Y |
B |
-0.5626 |
|
| 37 |
Q |
B |
0.0000 |
|
| 38 |
Q |
B |
-2.1267 |
|
| 39 |
R |
B |
-3.0591 |
|
| 40 |
T |
B |
-2.1056 |
|
| 41 |
N |
B |
-1.9586 |
|
| 42 |
G |
B |
-1.8505 |
|
| 43 |
S |
B |
-1.4313 |
|
| 44 |
P |
B |
-1.6091 |
|
| 45 |
R |
B |
-1.7529 |
|
| 46 |
L |
B |
-0.7563 |
|
| 47 |
L |
B |
0.0000 |
|
| 48 |
I |
B |
0.0000 |
|
| 49 |
K |
B |
-1.5422 |
|
| 50 |
Y |
B |
-1.0668 |
|
| 51 |
A |
B |
0.0000 |
|
| 52 |
D |
B |
-2.9030 |
|
| 53 |
E |
B |
-3.0318 |
|
| 54 |
S |
B |
-1.9476 |
|
| 55 |
I |
B |
-1.4920 |
|
| 56 |
D |
B |
-2.0070 |
|
| 57 |
G |
B |
-1.1632 |
|
| 58 |
I |
B |
-0.7309 |
|
| 59 |
P |
B |
-0.5300 |
|
| 60 |
S |
B |
-0.7750 |
|
| 61 |
R |
B |
-1.1897 |
|
| 62 |
F |
B |
0.0000 |
|
| 63 |
S |
B |
-1.3890 |
|
| 64 |
G |
B |
-1.4502 |
|
| 65 |
S |
B |
-1.4502 |
|
| 66 |
G |
B |
-1.4159 |
|
| 67 |
S |
B |
-1.1815 |
|
| 68 |
G |
B |
-1.4107 |
|
| 69 |
T |
B |
-2.0024 |
|
| 70 |
D |
B |
-2.8134 |
|
| 71 |
F |
B |
0.0000 |
|
| 72 |
T |
B |
-1.1129 |
|
| 73 |
L |
B |
0.0000 |
|
| 74 |
S |
B |
-0.9720 |
|
| 75 |
I |
B |
0.0000 |
|
| 76 |
N |
B |
-2.8134 |
|
| 77 |
S |
B |
-2.4628 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
E |
B |
-2.4092 |
|
| 80 |
S |
B |
-2.2236 |
|
| 81 |
E |
B |
-2.7234 |
|
| 82 |
D |
B |
0.0000 |
|
| 83 |
I |
B |
-1.5647 |
|
| 84 |
A |
B |
0.0000 |
|
| 85 |
D |
B |
-1.0369 |
|
| 86 |
Y |
B |
0.0000 |
|
| 87 |
Y |
B |
0.0788 |
|
| 88 |
C |
B |
0.0000 |
|
| 89 |
Q |
B |
0.2646 |
|
| 90 |
Q |
B |
0.0000 |
|
| 91 |
N |
B |
-0.9553 |
|
| 92 |
N |
B |
-1.3931 |
|
| 93 |
N |
B |
-1.0344 |
|
| 94 |
W |
B |
0.2744 |
|
| 95 |
P |
B |
0.0432 |
|
| 96 |
T |
B |
-0.0259 |
|
| 97 |
T |
B |
0.5267 |
|
| 98 |
F |
B |
1.5674 |
|
| 99 |
G |
B |
0.7215 |
|
| 100 |
A |
B |
0.4430 |
|
| 101 |
G |
B |
0.3243 |
|
| 102 |
T |
B |
0.0000 |
|
| 103 |
K |
B |
-0.4071 |
|
| 104 |
L |
B |
0.0000 |
|
| 105 |
E |
B |
-0.9773 |
|
| 106 |
L |
B |
0.0000 |
|
| 107 |
K |
B |
-1.7183 |
|
| 108 |
R |
B |
-1.3350 |
|
| 109 |
T |
B |
-0.2898 |
|
| 110 |
V |
B |
0.1818 |
|
| 111 |
A |
B |
-0.1143 |
|
| 112 |
A |
B |
-0.3148 |
|
| 113 |
P |
B |
0.0000 |
|
| 114 |
S |
B |
-0.1669 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
F |
B |
1.2395 |
|
| 117 |
I |
B |
1.2521 |
|
| 118 |
F |
B |
1.4813 |
|
| 119 |
P |
B |
0.1097 |
|
| 120 |
P |
B |
0.0000 |
|
| 121 |
S |
B |
-1.8020 |
|
| 122 |
D |
B |
-3.2156 |
|
| 123 |
E |
B |
-3.4334 |
|
| 124 |
Q |
B |
-2.4760 |
|
| 125 |
L |
B |
-2.3138 |
|
| 126 |
K |
B |
-2.9961 |
|
| 127 |
S |
B |
-1.8464 |
|
| 128 |
G |
B |
-1.2676 |
|
| 129 |
T |
B |
-1.0516 |
|
| 130 |
A |
B |
0.0000 |
|
| 131 |
S |
B |
0.0779 |
|
| 132 |
V |
B |
0.0000 |
|
| 133 |
V |
B |
0.7700 |
|
| 134 |
C |
B |
0.0000 |
|
| 135 |
L |
B |
0.5569 |
|
| 136 |
L |
B |
0.0000 |
|
| 137 |
N |
B |
-0.6421 |
|
| 138 |
N |
B |
-1.2537 |
|
| 139 |
F |
B |
0.0000 |
|
| 140 |
Y |
B |
0.0000 |
|
| 141 |
P |
B |
-1.9527 |
|
| 142 |
R |
B |
-3.2418 |
|
| 143 |
E |
B |
-3.2319 |
|
| 144 |
A |
B |
-2.3380 |
|
| 145 |
K |
B |
-2.1866 |
|
| 146 |
V |
B |
-1.0871 |
|
| 147 |
Q |
B |
-0.7048 |
|
| 148 |
W |
B |
0.0000 |
|
| 149 |
K |
B |
-0.5129 |
|
| 150 |
V |
B |
0.0000 |
|
| 151 |
D |
B |
-1.8539 |
|
| 152 |
N |
B |
-1.5109 |
|
| 153 |
A |
B |
-0.3125 |
|
| 154 |
L |
B |
0.4956 |
|
| 155 |
Q |
B |
-0.3824 |
|
| 156 |
S |
B |
-0.8381 |
|
| 157 |
G |
B |
-1.3656 |
|
| 158 |
N |
B |
-1.6995 |
|
| 159 |
S |
B |
-1.8026 |
|
| 160 |
Q |
B |
-2.4766 |
|
| 161 |
E |
B |
-2.3532 |
|
| 162 |
S |
B |
-1.3678 |
|
| 163 |
V |
B |
-0.7954 |
|
| 164 |
T |
B |
-1.1888 |
|
| 165 |
E |
B |
-2.0897 |
|
| 166 |
Q |
B |
0.0000 |
|
| 167 |
D |
B |
-1.9988 |
|
| 168 |
S |
B |
-2.2235 |
|
| 169 |
K |
B |
-2.5882 |
|
| 170 |
D |
B |
-2.0469 |
|
| 171 |
S |
B |
-1.8563 |
|
| 172 |
T |
B |
0.0000 |
|
| 173 |
Y |
B |
0.0000 |
|
| 174 |
S |
B |
-0.9716 |
|
| 175 |
L |
B |
0.0000 |
|
| 176 |
S |
B |
-0.5623 |
|
| 177 |
S |
B |
0.0000 |
|
| 178 |
T |
B |
-0.7345 |
|
| 179 |
L |
B |
0.0000 |
|
| 180 |
T |
B |
-0.6375 |
|
| 181 |
L |
B |
-0.7449 |
|
| 182 |
S |
B |
-1.1287 |
|
| 183 |
K |
B |
-1.9844 |
|
| 184 |
A |
B |
-1.8866 |
|
| 185 |
D |
B |
-2.4116 |
|
| 186 |
Y |
B |
-2.3672 |
|
| 187 |
E |
B |
-3.6901 |
|
| 188 |
K |
B |
-3.6711 |
|
| 189 |
H |
B |
-3.3332 |
|
| 190 |
K |
B |
-3.2859 |
|
| 191 |
V |
B |
-1.6636 |
|
| 192 |
Y |
B |
0.0000 |
|
| 193 |
A |
B |
0.0000 |
|
| 194 |
C |
B |
0.0000 |
|
| 195 |
E |
B |
-0.7321 |
|
| 196 |
V |
B |
0.0000 |
|
| 197 |
T |
B |
-1.1839 |
|
| 198 |
H |
B |
0.0000 |
|
| 199 |
Q |
B |
-1.6289 |
|
| 200 |
G |
B |
-0.5439 |
|
| 201 |
L |
B |
-0.2856 |
|
| 202 |
S |
B |
-0.4554 |
|
| 203 |
S |
B |
-0.3998 |
|
| 204 |
P |
B |
-0.4717 |
|
| 205 |
V |
B |
0.1016 |
|
| 206 |
T |
B |
-0.3532 |
|
| 207 |
K |
B |
-0.4103 |
|
| 208 |
S |
B |
-0.4336 |
|
| 209 |
F |
B |
-0.6058 |
|
| 210 |
N |
B |
-2.0363 |
|