Project name: 5euk:B
Status: done
submitted: 2019-03-20 15:51:27, status changed: 2019-03-20 17:24:32
Settings
|
Chain sequence(s)
|
B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8819
-
Maximal score value
-
2.4331
-
Average score
-
-0.5385
-
Total score value
-
-118.4636
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
B |
-1.5301 |
|
| 2 |
V |
B |
-0.9618 |
|
| 3 |
Q |
B |
-1.8239 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
K |
B |
-2.3053 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.8227 |
|
| 8 |
G |
B |
-1.0656 |
|
| 9 |
P |
B |
-0.4208 |
|
| 10 |
G |
B |
-0.3592 |
|
| 11 |
L |
B |
0.0524 |
|
| 12 |
V |
B |
-0.6282 |
|
| 13 |
Q |
B |
-1.1787 |
|
| 14 |
P |
B |
-1.2508 |
|
| 15 |
S |
B |
-1.4341 |
|
| 16 |
Q |
B |
-1.7652 |
|
| 17 |
S |
B |
-1.4398 |
|
| 18 |
L |
B |
0.0000 |
|
| 19 |
S |
B |
-0.5431 |
|
| 20 |
I |
B |
0.0000 |
|
| 21 |
T |
B |
-0.4816 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
T |
B |
-1.2180 |
|
| 24 |
V |
B |
0.0000 |
|
| 25 |
S |
B |
-1.3612 |
|
| 26 |
G |
B |
-1.0723 |
|
| 27 |
F |
B |
-0.5804 |
|
| 28 |
S |
B |
-0.8792 |
|
| 29 |
L |
B |
0.0000 |
|
| 30 |
T |
B |
-0.8877 |
|
| 31 |
N |
B |
-0.8804 |
|
| 32 |
Y |
B |
0.3412 |
|
| 33 |
G |
B |
0.0000 |
|
| 34 |
V |
B |
0.0000 |
|
| 35 |
H |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.3100 |
|
| 40 |
S |
B |
-0.9295 |
|
| 41 |
P |
B |
-1.0823 |
|
| 42 |
G |
B |
-1.6005 |
|
| 43 |
K |
B |
-1.9849 |
|
| 44 |
G |
B |
-0.6130 |
|
| 45 |
L |
B |
0.7968 |
|
| 46 |
E |
B |
0.0000 |
|
| 47 |
W |
B |
0.4467 |
|
| 48 |
L |
B |
0.0000 |
|
| 49 |
G |
B |
0.0000 |
|
| 50 |
V |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
W |
B |
-0.5898 |
|
| 53 |
S |
B |
-0.6471 |
|
| 54 |
G |
B |
-1.2076 |
|
| 55 |
G |
B |
-1.4824 |
|
| 56 |
N |
B |
-1.8901 |
|
| 57 |
T |
B |
-1.4012 |
|
| 58 |
D |
B |
-1.3198 |
|
| 59 |
Y |
B |
-0.5766 |
|
| 60 |
N |
B |
-0.5791 |
|
| 61 |
T |
B |
-0.5047 |
|
| 62 |
P |
B |
-0.4673 |
|
| 63 |
F |
B |
0.0000 |
|
| 64 |
T |
B |
-0.5706 |
|
| 65 |
S |
B |
-0.5395 |
|
| 66 |
R |
B |
-0.9157 |
|
| 67 |
L |
B |
0.0000 |
|
| 68 |
S |
B |
-0.9710 |
|
| 69 |
I |
B |
0.0000 |
|
| 70 |
N |
B |
-1.6603 |
|
| 71 |
K |
B |
-1.3800 |
|
| 72 |
D |
B |
-1.7057 |
|
| 73 |
N |
B |
-2.0968 |
|
| 74 |
S |
B |
-1.6371 |
|
| 75 |
K |
B |
-2.3389 |
|
| 76 |
S |
B |
-1.5980 |
|
| 77 |
Q |
B |
-1.5196 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
F |
B |
-0.1826 |
|
| 80 |
F |
B |
0.0000 |
|
| 81 |
K |
B |
-1.3219 |
|
| 82 |
M |
B |
0.0000 |
|
| 83 |
N |
B |
-1.5140 |
|
| 84 |
S |
B |
-1.3892 |
|
| 85 |
L |
B |
0.0000 |
|
| 86 |
Q |
B |
-2.0459 |
|
| 87 |
S |
B |
-1.4901 |
|
| 88 |
N |
B |
-2.0606 |
|
| 89 |
D |
B |
0.0000 |
|
| 90 |
T |
B |
-0.6913 |
|
| 91 |
A |
B |
0.0000 |
|
| 92 |
I |
B |
0.4661 |
|
| 93 |
Y |
B |
0.0000 |
|
| 94 |
Y |
B |
-0.1112 |
|
| 95 |
C |
B |
0.0000 |
|
| 96 |
A |
B |
0.0000 |
|
| 97 |
R |
B |
0.0000 |
|
| 98 |
A |
B |
0.0000 |
|
| 99 |
L |
B |
1.5435 |
|
| 100 |
T |
B |
1.2002 |
|
| 101 |
Y |
B |
1.8755 |
|
| 102 |
Y |
B |
1.5887 |
|
| 103 |
D |
B |
0.3901 |
|
| 104 |
Y |
B |
0.2372 |
|
| 105 |
E |
B |
-0.9383 |
|
| 106 |
F |
B |
0.1665 |
|
| 107 |
A |
B |
0.5693 |
|
| 108 |
Y |
B |
0.4224 |
|
| 109 |
W |
B |
0.0659 |
|
| 110 |
G |
B |
0.0000 |
|
| 111 |
Q |
B |
-1.5134 |
|
| 112 |
G |
B |
-0.6438 |
|
| 113 |
T |
B |
0.0000 |
|
| 114 |
L |
B |
0.2840 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
T |
B |
-0.2413 |
|
| 117 |
V |
B |
0.0000 |
|
| 118 |
S |
B |
-0.5612 |
|
| 119 |
A |
B |
-0.3373 |
|
| 120 |
A |
B |
-0.2481 |
|
| 121 |
S |
B |
-0.4694 |
|
| 122 |
T |
B |
-0.7398 |
|
| 123 |
K |
B |
-1.2513 |
|
| 124 |
G |
B |
-1.4403 |
|
| 125 |
P |
B |
0.0000 |
|
| 126 |
S |
B |
-0.0878 |
|
| 127 |
V |
B |
0.0000 |
|
| 128 |
F |
B |
0.9741 |
|
| 129 |
P |
B |
0.0327 |
|
| 130 |
L |
B |
0.1403 |
|
| 131 |
A |
B |
-1.0897 |
|
| 132 |
P |
B |
0.0000 |
|
| 133 |
S |
B |
-1.4384 |
|
| 134 |
S |
B |
-1.3581 |
|
| 135 |
K |
B |
-1.9098 |
|
| 136 |
S |
B |
-1.0368 |
|
| 137 |
T |
B |
-1.0222 |
|
| 138 |
S |
B |
-0.9730 |
|
| 139 |
G |
B |
-0.8545 |
|
| 140 |
G |
B |
-0.9174 |
|
| 141 |
T |
B |
-0.6592 |
|
| 142 |
A |
B |
0.0000 |
|
| 143 |
A |
B |
-0.2036 |
|
| 144 |
L |
B |
0.0000 |
|
| 145 |
G |
B |
0.0000 |
|
| 146 |
C |
B |
0.0000 |
|
| 147 |
L |
B |
0.7160 |
|
| 148 |
V |
B |
0.0000 |
|
| 149 |
K |
B |
-0.1746 |
|
| 150 |
D |
B |
-0.6089 |
|
| 151 |
Y |
B |
0.0000 |
|
| 152 |
F |
B |
0.0000 |
|
| 153 |
P |
B |
0.0000 |
|
| 154 |
E |
B |
-0.1016 |
|
| 155 |
P |
B |
-0.5409 |
|
| 156 |
V |
B |
-0.6395 |
|
| 157 |
T |
B |
-0.6285 |
|
| 158 |
V |
B |
-0.4270 |
|
| 159 |
S |
B |
-0.4605 |
|
| 160 |
W |
B |
0.0000 |
|
| 161 |
N |
B |
-0.8775 |
|
| 162 |
S |
B |
-0.7139 |
|
| 163 |
G |
B |
-0.5770 |
|
| 164 |
A |
B |
-0.2423 |
|
| 165 |
L |
B |
-0.0285 |
|
| 166 |
T |
B |
-0.2957 |
|
| 167 |
S |
B |
-0.3678 |
|
| 168 |
G |
B |
-0.4773 |
|
| 169 |
V |
B |
-0.0167 |
|
| 170 |
H |
B |
-0.4877 |
|
| 171 |
T |
B |
0.0685 |
|
| 172 |
F |
B |
0.8068 |
|
| 173 |
P |
B |
0.6334 |
|
| 174 |
A |
B |
1.2630 |
|
| 175 |
V |
B |
2.4331 |
|
| 176 |
L |
B |
2.0582 |
|
| 177 |
Q |
B |
0.6064 |
|
| 178 |
S |
B |
0.0339 |
|
| 179 |
S |
B |
-0.2514 |
|
| 180 |
G |
B |
0.1739 |
|
| 181 |
L |
B |
0.3061 |
|
| 182 |
Y |
B |
0.8626 |
|
| 183 |
S |
B |
0.0000 |
|
| 184 |
L |
B |
0.0000 |
|
| 185 |
S |
B |
0.6157 |
|
| 186 |
S |
B |
0.0000 |
|
| 187 |
V |
B |
0.4035 |
|
| 188 |
V |
B |
0.0000 |
|
| 189 |
T |
B |
-0.2314 |
|
| 190 |
V |
B |
0.0000 |
|
| 191 |
P |
B |
-0.6386 |
|
| 192 |
S |
B |
-0.6030 |
|
| 193 |
S |
B |
-0.5967 |
|
| 194 |
S |
B |
-0.6416 |
|
| 195 |
L |
B |
-0.8291 |
|
| 196 |
G |
B |
-0.9760 |
|
| 197 |
T |
B |
-0.7463 |
|
| 198 |
Q |
B |
-1.2816 |
|
| 199 |
T |
B |
-1.2351 |
|
| 200 |
Y |
B |
0.0000 |
|
| 201 |
I |
B |
-1.5921 |
|
| 202 |
C |
B |
0.0000 |
|
| 203 |
N |
B |
-1.6341 |
|
| 204 |
V |
B |
0.0000 |
|
| 205 |
N |
B |
-2.0974 |
|
| 206 |
H |
B |
0.0000 |
|
| 207 |
K |
B |
-2.7825 |
|
| 208 |
P |
B |
-1.5543 |
|
| 209 |
S |
B |
-1.8254 |
|
| 210 |
N |
B |
-2.5627 |
|
| 211 |
T |
B |
-2.1012 |
|
| 212 |
K |
B |
-2.7906 |
|
| 213 |
V |
B |
-1.9115 |
|
| 214 |
D |
B |
-2.7653 |
|
| 215 |
K |
B |
-2.2634 |
|
| 216 |
R |
B |
-2.6961 |
|
| 217 |
V |
B |
0.0000 |
|
| 218 |
E |
B |
-2.8819 |
|
| 219 |
P |
B |
-1.8922 |
|
| 220 |
K |
B |
-2.2402 |
|