Project name: 3wd5:H

Chain sequence(s)	H: EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSAITWNSGHIDYADSVEGRFTISRDNAKNSLYLDMNSLRAEDTAVYYCAKVSYLSTASSLDYWGQGTLVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKI
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8772
• Maximal score value: 2.5454
• Average score: -0.4985
• Total score value: -106.6791

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1346
2	V	H	-1.0036
3	Q	H	-1.0232
4	L	H	0.0000
5	V	H	1.1537
6	E	H	0.1934
7	S	H	-0.4421
8	G	H	-1.0042
9	G	H	-0.7416
10	G	H	-0.4077
11	L	H	-0.1484
12	V	H	0.0000
13	Q	H	-2.1860
14	P	H	-2.1223
15	G	H	-2.1942
16	R	H	-2.8065
17	S	H	-2.1774
18	L	H	-1.5026
19	R	H	-2.2171
20	L	H	0.0000
21	S	H	-0.4408
22	C	H	0.0000
23	A	H	-0.0987
24	A	H	0.0000
25	S	H	-1.0048
26	G	H	-1.3214
27	F	H	-0.8601
28	T	H	-0.9110
29	F	H	0.0000
30	D	H	-1.8958
31	D	H	-1.4592
32	Y	H	-0.0736
33	A	H	0.0000
34	M	H	0.0000
35	H	H	0.1586
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.2138
40	A	H	-0.8604
41	P	H	-0.7256
42	G	H	-1.0918
43	K	H	-1.3987
44	G	H	-0.5999
45	L	H	0.7753
46	E	H	0.0527
47	W	H	0.3141
48	V	H	0.0000
49	S	H	0.0000
50	A	H	0.0000
51	I	H	0.0000
52	T	H	-0.5414
53	W	H	-0.6328
54	N	H	-1.7624
55	S	H	-0.9906
56	G	H	-1.0668
57	H	H	-1.0633
58	I	H	-0.3286
59	D	H	-0.9945
60	Y	H	-1.0075
61	A	H	-1.4217
62	D	H	-2.1764
63	S	H	-1.3919
64	V	H	-1.4958
65	E	H	-2.4151
66	G	H	-1.5344
67	R	H	-1.3469
68	F	H	0.0000
69	T	H	-0.9503
70	I	H	0.0000
71	S	H	-0.2970
72	R	H	-1.0251
73	D	H	-1.6156
74	N	H	-1.9365
75	A	H	-1.4212
76	K	H	-2.2250
77	N	H	-1.8783
78	S	H	0.0000
79	L	H	0.0000
80	Y	H	-0.6601
81	L	H	0.0000
82	D	H	-1.5710
83	M	H	0.0000
84	N	H	-1.8768
85	S	H	-1.7719
86	L	H	0.0000
87	R	H	-2.8418
88	A	H	-1.8201
89	E	H	-2.3190
90	D	H	0.0000
91	T	H	-0.8798
92	A	H	0.0000
93	V	H	0.3104
94	Y	H	0.0000
95	Y	H	0.4390
96	C	H	0.0000
97	A	H	0.0000
98	K	H	0.0000
99	V	H	0.0000
100	S	H	0.2271
101	Y	H	1.2660
102	L	H	1.1910
103	S	H	0.6102
104	T	H	0.3541
105	A	H	0.2863
106	S	H	0.1995
107	S	H	-0.2289
108	L	H	-0.2802
109	D	H	-1.1860
110	Y	H	-0.3153
111	W	H	0.0931
112	G	H	-0.0302
113	Q	H	-0.8070
114	G	H	-0.2526
115	T	H	-0.0791
116	L	H	-0.0530
117	V	H	0.0000
118	T	H	-0.5080
119	V	H	0.0000
120	S	H	-0.7983
121	S	H	-0.7229
122	A	H	-0.4015
123	S	H	-0.5021
124	T	H	-0.7838
125	K	H	-1.0326
126	G	H	-1.3733
127	P	H	-0.6012
128	S	H	-0.1152
129	V	H	0.0000
130	F	H	1.0675
131	P	H	0.6137
132	L	H	0.8511
133	A	H	0.3497
134	P	H	-0.0304
135	S	H	-0.2645
136	S	H	-0.3260
142	G	H	-0.6293
143	T	H	-0.4763
144	A	H	-0.3285
145	A	H	0.0536
146	L	H	0.0000
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.8538
150	V	H	0.0000
151	K	H	-0.3109
152	D	H	-0.6219
153	Y	H	0.0000
154	F	H	-0.1875
155	P	H	0.0000
156	E	H	-0.6449
157	P	H	-0.7673
158	V	H	0.0000
159	T	H	-0.7114
160	V	H	-0.2139
161	S	H	-0.4018
162	W	H	0.0000
163	N	H	-0.7295
164	S	H	-0.6339
165	G	H	-0.5128
166	A	H	-0.1790
167	L	H	-0.0235
168	T	H	-0.3062
169	S	H	-0.3846
170	G	H	-0.4824
171	V	H	-0.0147
172	H	H	-0.4215
173	T	H	0.2496
174	F	H	1.1275
175	P	H	0.8083
176	A	H	1.2986
177	V	H	2.5454
178	L	H	2.2272
179	Q	H	0.7058
180	S	H	0.0701
181	S	H	-0.2227
182	G	H	0.2321
183	L	H	0.4162
184	Y	H	0.8703
185	S	H	0.7524
186	L	H	0.0000
187	S	H	0.7159
188	S	H	0.0000
189	V	H	0.4816
190	V	H	0.0000
191	T	H	-0.2633
192	V	H	0.0000
193	P	H	-0.4746
194	S	H	-0.5523
195	S	H	-0.5474
196	S	H	-0.4431
197	L	H	-0.2462
198	G	H	-0.5756
199	T	H	-0.5448
200	Q	H	-0.7468
201	T	H	-0.5948
202	Y	H	0.0000
203	I	H	-0.8114
204	C	H	0.0000
205	N	H	-1.4449
206	V	H	0.0000
207	N	H	-2.0712
208	H	H	0.0000
209	K	H	-2.8772
210	P	H	-1.6683
211	S	H	-1.7679
212	N	H	-2.6076
213	T	H	-2.0937
214	K	H	-2.7420
215	V	H	-1.4183
216	D	H	-2.3490
217	K	H	-1.6997
218	K	H	-1.6924
219	I	H	-0.1382