Project name: GCSF2
Status: done
submitted: 2018-11-30 11:57:23, status changed: 2018-11-30 12:03:45
Settings
|
Chain sequence(s)
|
A: GPASSLPQSFLLKCLEQVRKIQGDGAALQEKLCATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSYRVLRHLAQP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-3.043
-
Maximal score value
-
1.6195
-
Average score
-
-0.6408
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Total score value
-
-109.5793
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 5 |
G |
A |
-0.6214 |
|
| 6 |
P |
A |
-0.6939 |
|
| 7 |
A |
A |
-0.3015 |
|
| 8 |
S |
A |
-0.4237 |
|
| 9 |
S |
A |
-0.0757 |
|
| 10 |
L |
A |
0.0000 |
|
| 11 |
P |
A |
-0.6010 |
|
| 12 |
Q |
A |
-1.4813 |
|
| 13 |
S |
A |
-0.8657 |
|
| 14 |
F |
A |
0.0000 |
|
| 15 |
L |
A |
0.0000 |
|
| 16 |
L |
A |
-0.7565 |
|
| 17 |
K |
A |
-1.5805 |
|
| 18 |
C |
A |
0.0000 |
|
| 19 |
L |
A |
0.0000 |
|
| 20 |
E |
A |
-2.4494 |
|
| 21 |
Q |
A |
-2.3390 |
|
| 22 |
V |
A |
0.0000 |
|
| 23 |
R |
A |
-2.9794 |
|
| 24 |
K |
A |
-3.0430 |
|
| 25 |
I |
A |
0.0000 |
|
| 26 |
Q |
A |
-1.9978 |
|
| 27 |
G |
A |
-1.6624 |
|
| 28 |
D |
A |
-1.6579 |
|
| 29 |
G |
A |
-1.2906 |
|
| 30 |
A |
A |
-1.2590 |
|
| 31 |
A |
A |
-1.1723 |
|
| 32 |
L |
A |
0.0000 |
|
| 33 |
Q |
A |
-1.5307 |
|
| 34 |
E |
A |
-2.4043 |
|
| 35 |
K |
A |
-2.0865 |
|
| 36 |
L |
A |
0.0000 |
|
| 37 |
C |
A |
-1.4002 |
|
| 38 |
A |
A |
-1.0580 |
|
| 39 |
T |
A |
-1.0338 |
|
| 40 |
Y |
A |
-0.6265 |
|
| 41 |
K |
A |
-1.7277 |
|
| 42 |
L |
A |
-1.2527 |
|
| 43 |
C |
A |
-1.4834 |
|
| 44 |
H |
A |
-1.9971 |
|
| 45 |
P |
A |
-1.3511 |
|
| 46 |
E |
A |
-2.1659 |
|
| 47 |
E |
A |
-2.1187 |
|
| 48 |
L |
A |
0.0000 |
|
| 49 |
V |
A |
1.0541 |
|
| 50 |
L |
A |
1.6195 |
|
| 51 |
L |
A |
0.8193 |
|
| 52 |
G |
A |
0.5480 |
|
| 53 |
H |
A |
-0.4395 |
|
| 54 |
S |
A |
-0.0911 |
|
| 55 |
L |
A |
-0.1680 |
|
| 56 |
G |
A |
-0.5202 |
|
| 57 |
I |
A |
0.0000 |
|
| 58 |
P |
A |
0.3066 |
|
| 59 |
W |
A |
1.0340 |
|
| 60 |
A |
A |
0.0000 |
|
| 61 |
P |
A |
0.1883 |
|
| 62 |
L |
A |
0.0095 |
|
| 63 |
S |
A |
-0.3512 |
|
| 64 |
S |
A |
-0.4728 |
|
| 65 |
C |
A |
0.0000 |
|
| 66 |
P |
A |
-0.7496 |
|
| 67 |
S |
A |
-0.7752 |
|
| 68 |
Q |
A |
-0.8403 |
|
| 69 |
A |
A |
-0.3783 |
|
| 70 |
L |
A |
0.1567 |
|
| 71 |
Q |
A |
-0.9758 |
|
| 72 |
L |
A |
0.0000 |
|
| 73 |
A |
A |
-0.3580 |
|
| 74 |
G |
A |
-0.6029 |
|
| 75 |
C |
A |
0.0000 |
|
| 76 |
L |
A |
0.0000 |
|
| 77 |
S |
A |
-0.2561 |
|
| 78 |
Q |
A |
-0.3746 |
|
| 79 |
L |
A |
0.0000 |
|
| 80 |
H |
A |
0.0000 |
|
| 81 |
S |
A |
-0.4369 |
|
| 82 |
G |
A |
0.0000 |
|
| 83 |
L |
A |
0.0000 |
|
| 84 |
F |
A |
-0.2476 |
|
| 85 |
L |
A |
-0.0687 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Q |
A |
-0.6795 |
|
| 88 |
G |
A |
-0.6952 |
|
| 89 |
L |
A |
0.0000 |
|
| 90 |
L |
A |
0.0000 |
|
| 91 |
Q |
A |
-1.8238 |
|
| 92 |
A |
A |
-1.2609 |
|
| 93 |
L |
A |
0.0000 |
|
| 94 |
E |
A |
-2.4366 |
|
| 95 |
G |
A |
-1.9935 |
|
| 96 |
I |
A |
0.0000 |
|
| 97 |
S |
A |
-1.2977 |
|
| 98 |
P |
A |
-1.2637 |
|
| 99 |
E |
A |
-2.1678 |
|
| 100 |
L |
A |
0.0000 |
|
| 101 |
G |
A |
-1.4616 |
|
| 102 |
P |
A |
-1.1124 |
|
| 103 |
T |
A |
-1.0605 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
D |
A |
-1.2651 |
|
| 106 |
T |
A |
-0.3601 |
|
| 107 |
L |
A |
0.0000 |
|
| 108 |
Q |
A |
-0.6525 |
|
| 109 |
L |
A |
0.2891 |
|
| 110 |
D |
A |
-0.9391 |
|
| 111 |
V |
A |
0.0000 |
|
| 112 |
A |
A |
-0.5390 |
|
| 113 |
D |
A |
-1.5802 |
|
| 114 |
F |
A |
0.0000 |
|
| 115 |
A |
A |
0.0000 |
|
| 116 |
T |
A |
-1.0038 |
|
| 117 |
T |
A |
-1.0447 |
|
| 118 |
I |
A |
0.0000 |
|
| 119 |
W |
A |
-1.4926 |
|
| 120 |
Q |
A |
-2.2228 |
|
| 121 |
Q |
A |
0.0000 |
|
| 122 |
M |
A |
0.0000 |
|
| 123 |
E |
A |
-3.0116 |
|
| 124 |
E |
A |
-2.7844 |
|
| 125 |
L |
A |
-1.1206 |
|
| 126 |
G |
A |
-1.4301 |
|
| 127 |
M |
A |
-0.8980 |
|
| 128 |
A |
A |
-1.0339 |
|
| 129 |
P |
A |
-0.1172 |
|
| 130 |
A |
A |
0.4676 |
|
| 131 |
L |
A |
0.9312 |
|
| 132 |
Q |
A |
-0.6781 |
|
| 133 |
P |
A |
-0.6489 |
|
| 134 |
T |
A |
-0.7217 |
|
| 135 |
Q |
A |
-1.3988 |
|
| 136 |
G |
A |
-0.4603 |
|
| 137 |
A |
A |
-0.1948 |
|
| 138 |
M |
A |
-0.0647 |
|
| 139 |
P |
A |
0.0500 |
|
| 140 |
A |
A |
0.0111 |
|
| 141 |
F |
A |
0.0000 |
|
| 142 |
A |
A |
0.1058 |
|
| 143 |
S |
A |
0.1286 |
|
| 144 |
A |
A |
0.2883 |
|
| 145 |
F |
A |
0.8787 |
|
| 146 |
Q |
A |
0.0661 |
|
| 147 |
R |
A |
-0.7023 |
|
| 148 |
R |
A |
-0.2355 |
|
| 149 |
A |
A |
0.0000 |
|
| 150 |
G |
A |
0.0000 |
|
| 151 |
G |
A |
0.0000 |
|
| 152 |
V |
A |
0.0000 |
|
| 153 |
L |
A |
0.0000 |
|
| 154 |
V |
A |
0.0000 |
|
| 155 |
A |
A |
0.0000 |
|
| 156 |
S |
A |
-0.5312 |
|
| 157 |
H |
A |
-0.3017 |
|
| 158 |
L |
A |
0.0000 |
|
| 159 |
Q |
A |
-0.8160 |
|
| 160 |
S |
A |
-0.4958 |
|
| 161 |
F |
A |
0.0000 |
|
| 162 |
L |
A |
0.0000 |
|
| 163 |
E |
A |
-1.3082 |
|
| 164 |
V |
A |
-0.2184 |
|
| 165 |
S |
A |
0.0000 |
|
| 166 |
Y |
A |
-1.5779 |
|
| 167 |
R |
A |
-2.3452 |
|
| 168 |
V |
A |
0.0000 |
|
| 169 |
L |
A |
0.0000 |
|
| 170 |
R |
A |
-2.3317 |
|
| 171 |
H |
A |
-2.4358 |
|
| 172 |
L |
A |
-1.5094 |
|
| 173 |
A |
A |
0.0000 |
|
| 174 |
Q |
A |
-2.0476 |
|
| 175 |
P |
A |
-1.1635 |
|