Project name: 61f38b17d92dd22

Chain sequence(s)	A: AAIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPT; B: NEKVSCV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2758
• Maximal score value: 1.5073
• Average score: -0.6947
• Total score value: -68.7728

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
315	A	A	0.4545
316	A	A	0.8467
317	I	A	1.5073
318	M	A	-0.1751
319	E	A	-1.7574
320	I	A	0.0000
321	K	A	-1.2469
322	L	A	0.0000
323	I	A	1.2651
324	K	A	-0.4926
325	G	A	-0.7584
326	P	A	-1.2899
327	K	A	-1.9771
328	G	A	-1.3321
329	L	A	0.0000
330	G	A	0.0000
331	F	A	0.0000
332	S	A	0.5040
333	I	A	0.0000
334	A	A	0.0000
335	G	A	0.0000
336	G	A	0.0000
337	V	A	-0.6548
338	G	A	-0.5904
339	N	A	-1.3571
340	Q	A	-1.3585
341	H	A	-0.7495
342	I	A	0.2926
343	P	A	-0.3892
344	G	A	-0.7463
345	D	A	-0.8432
346	N	A	-1.2431
347	S	A	0.0000
348	I	A	0.0000
349	Y	A	0.0696
350	V	A	0.0000
351	T	A	-0.0550
352	K	A	-1.0479
353	I	A	-0.8921
354	I	A	-1.0798
355	E	A	-2.3257
356	G	A	-1.9730
357	G	A	-1.8964
358	A	A	-1.3778
359	A	A	0.0000
360	H	A	-2.9297
361	K	A	-3.2758
362	D	A	-2.9614
363	G	A	-2.7858
364	K	A	-3.0418
365	L	A	0.0000
366	Q	A	-1.1212
367	I	A	0.7926
368	G	A	0.0669
369	D	A	0.0000
370	K	A	-0.4926
371	L	A	0.0000
372	L	A	-0.5347
373	A	A	-0.2805
374	V	A	0.0000
375	N	A	-0.0508
376	S	A	0.2605
377	V	A	0.6893
378	C	A	0.0515
379	L	A	0.0000
380	E	A	-2.2519
381	E	A	-2.5404
382	V	A	-1.7141
383	T	A	-1.5584
384	H	A	0.0000
385	E	A	-2.6296
386	E	A	-2.4290
387	A	A	0.0000
388	V	A	-1.3291
389	T	A	-1.9422
390	A	A	-1.4083
391	L	A	0.0000
392	K	A	-2.2283
393	N	A	-2.1367
394	T	A	-1.3964
395	S	A	-1.0204
396	D	A	-0.6279
397	F	A	1.3781
398	V	A	0.0000
399	Y	A	0.2031
400	L	A	0.0000
401	K	A	-1.0050
402	V	A	0.0000
403	A	A	0.0000
404	K	A	-0.0567
405	P	A	-0.4312
406	T	A	-0.2448
14	N	B	-2.1017
15	E	B	-2.3861
16	K	B	-1.9332
17	V	B	0.2657
18	S	B	0.3704
19	C	B	0.7682
20	V	B	-0.1039