Project name: 6bgt:B

Chain sequence(s)	B: EVQLVESGGGLVQPGGSLRLSCAASGFNIDDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSSASTKGPSVFPLAPTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8757
• Maximal score value: 2.3846
• Average score: -0.5153
• Total score value: -108.2204

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.0416
2	V	B	-1.1845
3	Q	B	-1.0727
4	L	B	0.0000
5	V	B	0.8026
6	E	B	0.1789
7	S	B	-0.4295
8	G	B	-0.9610
9	G	B	-0.5994
10	G	B	-0.2547
11	L	B	-0.0112
12	V	B	-0.5784
13	Q	B	-1.5171
14	P	B	-1.6803
15	G	B	-1.4576
16	G	B	-1.2066
17	S	B	-1.4862
18	L	B	-1.4046
19	R	B	-2.3695
20	L	B	0.0000
21	S	B	-0.5077
22	C	B	0.0000
23	A	B	-0.1564
24	A	B	0.0000
25	S	B	-0.9658
26	G	B	-1.4811
27	F	B	-1.4390
28	N	B	-2.2438
29	I	B	0.0000
30	D	B	-2.1835
31	D	B	-2.7695
32	T	B	0.0000
33	Y	B	-0.1677
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.4819
40	A	B	-1.0770
41	P	B	-1.0695
42	G	B	-1.5766
43	K	B	-2.0789
44	G	B	-0.9043
45	L	B	0.6504
46	E	B	-0.1602
47	W	B	0.2259
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-0.7882
51	I	B	0.0000
52	Y	B	-0.3098
53	P	B	-0.9087
54	T	B	-0.8985
55	N	B	-0.7475
56	G	B	-0.4238
57	Y	B	0.5119
58	T	B	-0.5408
59	R	B	-2.0991
60	Y	B	-1.8508
61	A	B	-1.8101
62	D	B	-2.6253
63	S	B	-1.5901
64	V	B	0.0000
65	K	B	-2.8579
66	G	B	-1.8938
67	R	B	-1.7283
68	F	B	0.0000
69	T	B	-1.3873
70	I	B	0.0000
71	S	B	-0.1886
72	A	B	-0.6715
73	D	B	-1.3605
74	T	B	-1.5244
75	S	B	-1.5423
76	K	B	-2.2484
77	N	B	-1.7778
78	T	B	0.0000
79	A	B	0.0000
80	Y	B	-0.6404
81	L	B	0.0000
82	Q	B	-1.8044
83	M	B	0.0000
84	N	B	-2.2704
85	S	B	-1.5756
86	L	B	0.0000
87	R	B	-2.5109
88	A	B	-1.7824
89	E	B	-2.2905
90	D	B	0.0000
91	T	B	-0.7794
92	A	B	0.0000
93	V	B	0.3109
94	Y	B	0.0000
95	Y	B	0.3021
96	C	B	0.0000
97	S	B	0.0000
98	R	B	0.0000
99	W	B	0.4934
100	G	B	0.2102
101	G	B	-0.6774
102	D	B	-1.6923
103	G	B	-0.2383
104	F	B	1.4112
105	Y	B	1.6596
106	A	B	1.0784
107	M	B	0.7836
108	D	B	0.2135
109	Y	B	0.4162
110	W	B	0.4826
111	G	B	0.0000
112	Q	B	-0.8048
113	G	B	-0.2988
114	T	B	-0.1055
115	L	B	0.0048
116	V	B	0.0000
117	T	B	0.0000
118	V	B	0.0000
119	S	B	-0.9029
120	S	B	-0.6535
121	A	B	-0.4867
122	S	B	-0.6930
123	T	B	-0.8348
124	K	B	-1.7435
125	G	B	-1.7371
126	P	B	-0.8030
127	S	B	-0.2528
128	V	B	0.0000
129	F	B	1.0254
130	P	B	0.4914
131	L	B	0.6988
132	A	B	0.2484
133	P	B	0.0099
142	T	B	-0.2911
143	A	B	-0.1757
144	A	B	0.0485
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.6979
149	V	B	0.0000
150	K	B	-0.6339
151	D	B	-0.7656
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.5940
156	P	B	-0.7147
157	V	B	-0.6999
158	T	B	-0.5726
159	V	B	-0.1970
160	S	B	-0.3137
161	W	B	0.0000
162	N	B	-0.6693
163	S	B	-0.5863
164	G	B	-0.5421
165	A	B	-0.2205
166	L	B	0.0001
167	T	B	-0.2721
168	S	B	-0.3066
169	G	B	-0.3269
170	V	B	0.0376
171	H	B	-0.3708
172	T	B	0.4333
173	F	B	1.5604
174	P	B	0.9679
175	A	B	1.3149
176	V	B	2.3846
177	L	B	1.7493
178	Q	B	0.3818
179	S	B	-0.0791
180	S	B	-0.3178
181	G	B	0.1102
182	L	B	0.1247
183	Y	B	0.6902
184	S	B	0.5390
185	L	B	0.0000
186	S	B	0.7600
187	S	B	0.0000
188	V	B	0.4776
189	V	B	0.0000
190	T	B	-0.2165
191	V	B	0.0000
192	P	B	-0.3862
193	S	B	-0.4357
194	S	B	-0.4926
195	S	B	-0.5011
196	L	B	-0.2315
197	G	B	-0.6374
198	T	B	-0.7086
199	Q	B	-1.0637
200	T	B	-0.7592
201	Y	B	0.0000
202	I	B	-1.0285
203	C	B	0.0000
204	N	B	0.0000
205	V	B	0.0000
206	N	B	-1.8718
207	H	B	0.0000
208	K	B	-2.8757
209	P	B	-1.7220
210	S	B	-2.0206
211	N	B	-2.7532
212	T	B	-2.2157
213	K	B	-2.6050
214	V	B	-1.4203
215	D	B	-2.0286
216	K	B	-1.5663
217	K	B	-1.6371
218	V	B	-0.0118