Project name: 4llu:B
Status: done
submitted: 2019-03-21 13:04:02, status changed: 2019-03-21 13:11:26
Settings
|
Chain sequence(s)
|
B: DIQMTQSPSSLSASVGDRVTITCKASQDVSIGVAWYQQKPGKAPKLLIYSASYRYTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYYIYPYTFGQGTKVEIKGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.2074
-
Maximal score value
-
2.3824
-
Average score
-
-0.7159
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Total score value
-
-150.3416
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
B |
-1.8925 |
|
| 2 |
I |
B |
-0.9453 |
|
| 3 |
Q |
B |
-1.9532 |
|
| 4 |
M |
B |
0.0000 |
|
| 5 |
T |
B |
-1.1949 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.7857 |
|
| 8 |
P |
B |
-0.4995 |
|
| 9 |
S |
B |
-0.8757 |
|
| 10 |
S |
B |
-0.9701 |
|
| 11 |
L |
B |
-0.6612 |
|
| 12 |
S |
B |
-1.0155 |
|
| 13 |
A |
B |
0.0000 |
|
| 14 |
S |
B |
-1.1514 |
|
| 15 |
V |
B |
-0.7079 |
|
| 16 |
G |
B |
-1.1024 |
|
| 17 |
D |
B |
-1.8282 |
|
| 18 |
R |
B |
-2.3767 |
|
| 19 |
V |
B |
0.0000 |
|
| 20 |
T |
B |
-0.6045 |
|
| 21 |
I |
B |
0.0000 |
|
| 22 |
T |
B |
-0.8607 |
|
| 23 |
C |
B |
0.0000 |
|
| 24 |
K |
B |
-2.5765 |
|
| 25 |
A |
B |
0.0000 |
|
| 26 |
S |
B |
-2.1183 |
|
| 27 |
Q |
B |
-2.3214 |
|
| 28 |
D |
B |
-2.6270 |
|
| 29 |
V |
B |
0.0000 |
|
| 30 |
S |
B |
-0.6205 |
|
| 31 |
I |
B |
0.3185 |
|
| 32 |
G |
B |
0.0000 |
|
| 33 |
V |
B |
0.0000 |
|
| 34 |
A |
B |
0.0000 |
|
| 35 |
W |
B |
0.0000 |
|
| 36 |
Y |
B |
0.0959 |
|
| 37 |
Q |
B |
0.0000 |
|
| 38 |
Q |
B |
-1.4374 |
|
| 39 |
K |
B |
-1.9074 |
|
| 40 |
P |
B |
-1.4890 |
|
| 41 |
G |
B |
-1.5913 |
|
| 42 |
K |
B |
-2.3911 |
|
| 43 |
A |
B |
-1.3759 |
|
| 44 |
P |
B |
-1.2376 |
|
| 45 |
K |
B |
-1.2507 |
|
| 46 |
L |
B |
-0.0711 |
|
| 47 |
L |
B |
0.0000 |
|
| 48 |
I |
B |
0.0000 |
|
| 49 |
Y |
B |
0.9598 |
|
| 50 |
S |
B |
0.6146 |
|
| 51 |
A |
B |
0.0000 |
|
| 52 |
S |
B |
0.2922 |
|
| 53 |
Y |
B |
0.9675 |
|
| 54 |
R |
B |
-0.1380 |
|
| 55 |
Y |
B |
0.4349 |
|
| 56 |
T |
B |
0.0102 |
|
| 57 |
G |
B |
-0.5235 |
|
| 58 |
V |
B |
0.0000 |
|
| 59 |
P |
B |
-0.5313 |
|
| 60 |
S |
B |
-0.6638 |
|
| 61 |
R |
B |
-0.9907 |
|
| 62 |
F |
B |
0.0000 |
|
| 63 |
S |
B |
-0.4226 |
|
| 64 |
G |
B |
-0.2315 |
|
| 65 |
S |
B |
-0.4796 |
|
| 66 |
G |
B |
-0.9075 |
|
| 67 |
S |
B |
-1.1734 |
|
| 68 |
G |
B |
-1.7216 |
|
| 69 |
T |
B |
-2.2537 |
|
| 70 |
D |
B |
-2.7451 |
|
| 71 |
F |
B |
0.0000 |
|
| 72 |
T |
B |
-0.8477 |
|
| 73 |
L |
B |
0.0000 |
|
| 74 |
T |
B |
-0.6251 |
|
| 75 |
I |
B |
0.0000 |
|
| 76 |
S |
B |
-1.4490 |
|
| 77 |
S |
B |
-1.2966 |
|
| 78 |
L |
B |
0.0000 |
|
| 79 |
Q |
B |
-1.2088 |
|
| 80 |
P |
B |
-1.5799 |
|
| 81 |
E |
B |
-2.2070 |
|
| 82 |
D |
B |
0.0000 |
|
| 83 |
F |
B |
0.0000 |
|
| 84 |
A |
B |
0.0000 |
|
| 85 |
T |
B |
-1.0994 |
|
| 86 |
Y |
B |
0.0000 |
|
| 87 |
Y |
B |
-0.0742 |
|
| 88 |
C |
B |
0.0000 |
|
| 89 |
Q |
B |
0.0000 |
|
| 90 |
Q |
B |
0.0000 |
|
| 91 |
Y |
B |
2.0008 |
|
| 92 |
Y |
B |
2.3824 |
|
| 93 |
I |
B |
2.3819 |
|
| 94 |
Y |
B |
2.0637 |
|
| 95 |
P |
B |
1.3626 |
|
| 96 |
Y |
B |
2.1588 |
|
| 97 |
T |
B |
0.8834 |
|
| 98 |
F |
B |
0.8926 |
|
| 99 |
G |
B |
0.0000 |
|
| 100 |
Q |
B |
-1.2228 |
|
| 101 |
G |
B |
0.0000 |
|
| 102 |
T |
B |
0.0000 |
|
| 103 |
K |
B |
-1.9428 |
|
| 104 |
V |
B |
0.0000 |
|
| 105 |
E |
B |
-1.7248 |
|
| 106 |
I |
B |
0.0000 |
|
| 107 |
K |
B |
-1.7736 |
|
| 108 |
G |
B |
-1.4762 |
|
| 109 |
Q |
B |
-1.4417 |
|
| 110 |
P |
B |
-1.5508 |
|
| 111 |
K |
B |
-2.3441 |
|
| 112 |
A |
B |
-1.3656 |
|
| 113 |
A |
B |
-0.7352 |
|
| 114 |
P |
B |
0.0000 |
|
| 115 |
S |
B |
-0.4095 |
|
| 116 |
V |
B |
0.0000 |
|
| 117 |
T |
B |
0.2168 |
|
| 118 |
L |
B |
0.0000 |
|
| 119 |
F |
B |
2.0150 |
|
| 120 |
P |
B |
0.8402 |
|
| 121 |
P |
B |
0.0000 |
|
| 122 |
S |
B |
-1.0721 |
|
| 123 |
S |
B |
-1.8662 |
|
| 124 |
E |
B |
-2.9128 |
|
| 125 |
E |
B |
-2.6076 |
|
| 126 |
L |
B |
-2.5276 |
|
| 127 |
Q |
B |
-2.6955 |
|
| 128 |
A |
B |
-2.2463 |
|
| 129 |
N |
B |
-3.0248 |
|
| 130 |
K |
B |
-3.1616 |
|
| 131 |
A |
B |
0.0000 |
|
| 132 |
T |
B |
-0.0653 |
|
| 133 |
L |
B |
0.0000 |
|
| 134 |
V |
B |
1.2599 |
|
| 135 |
C |
B |
0.0000 |
|
| 136 |
L |
B |
0.9794 |
|
| 137 |
I |
B |
0.0000 |
|
| 138 |
S |
B |
-0.5840 |
|
| 139 |
D |
B |
-1.4752 |
|
| 140 |
F |
B |
0.0000 |
|
| 141 |
Y |
B |
0.0000 |
|
| 142 |
P |
B |
-1.4447 |
|
| 143 |
G |
B |
-0.7130 |
|
| 144 |
A |
B |
-0.2496 |
|
| 145 |
V |
B |
-0.1259 |
|
| 146 |
T |
B |
-0.1336 |
|
| 147 |
V |
B |
-0.0496 |
|
| 148 |
A |
B |
-0.4513 |
|
| 149 |
W |
B |
0.0000 |
|
| 150 |
K |
B |
-1.0546 |
|
| 151 |
A |
B |
0.0000 |
|
| 152 |
D |
B |
-1.4657 |
|
| 153 |
S |
B |
-0.9790 |
|
| 154 |
S |
B |
-0.8391 |
|
| 155 |
P |
B |
-0.9222 |
|
| 156 |
V |
B |
-0.8557 |
|
| 157 |
K |
B |
-1.7740 |
|
| 158 |
A |
B |
-0.9538 |
|
| 159 |
G |
B |
-0.7637 |
|
| 160 |
V |
B |
-0.6104 |
|
| 161 |
E |
B |
-1.6053 |
|
| 162 |
T |
B |
-0.5905 |
|
| 163 |
T |
B |
-0.4644 |
|
| 164 |
T |
B |
-0.3428 |
|
| 165 |
P |
B |
-0.5066 |
|
| 166 |
S |
B |
-1.0290 |
|
| 167 |
K |
B |
-1.9985 |
|
| 168 |
Q |
B |
-1.6928 |
|
| 169 |
S |
B |
-1.5942 |
|
| 170 |
N |
B |
-2.2179 |
|
| 171 |
N |
B |
-2.0054 |
|
| 172 |
K |
B |
-1.9113 |
|
| 173 |
Y |
B |
-1.2662 |
|
| 174 |
A |
B |
-0.6210 |
|
| 175 |
A |
B |
0.0000 |
|
| 176 |
S |
B |
0.0485 |
|
| 177 |
S |
B |
0.0000 |
|
| 178 |
Y |
B |
0.4632 |
|
| 179 |
L |
B |
0.0000 |
|
| 180 |
S |
B |
-0.6458 |
|
| 181 |
L |
B |
0.0000 |
|
| 182 |
T |
B |
-1.9474 |
|
| 183 |
P |
B |
-2.6381 |
|
| 184 |
E |
B |
-3.2074 |
|
| 185 |
Q |
B |
-2.3191 |
|
| 186 |
W |
B |
0.0000 |
|
| 187 |
K |
B |
-3.1173 |
|
| 188 |
S |
B |
-2.4381 |
|
| 189 |
H |
B |
-2.3959 |
|
| 190 |
R |
B |
-2.5110 |
|
| 191 |
S |
B |
-1.5379 |
|
| 192 |
Y |
B |
0.0000 |
|
| 193 |
S |
B |
0.0000 |
|
| 194 |
C |
B |
0.0000 |
|
| 195 |
Q |
B |
-1.0981 |
|
| 196 |
V |
B |
0.0000 |
|
| 197 |
T |
B |
-0.7000 |
|
| 198 |
H |
B |
0.0000 |
|
| 199 |
E |
B |
-2.2850 |
|
| 200 |
G |
B |
-1.4303 |
|
| 201 |
S |
B |
-0.8838 |
|
| 202 |
T |
B |
-0.7250 |
|
| 203 |
V |
B |
-0.6769 |
|
| 204 |
E |
B |
-2.0956 |
|
| 205 |
K |
B |
-1.4425 |
|
| 206 |
T |
B |
-0.9150 |
|
| 207 |
V |
B |
0.0327 |
|
| 208 |
A |
B |
-0.5893 |
|
| 209 |
P |
B |
-0.9810 |
|
| 210 |
T |
B |
-0.3681 |
|