Project name: 4irz:L
Status: done
submitted: 2019-03-20 20:18:52, status changed: 2019-03-20 20:27:55
Settings
|
Chain sequence(s)
|
L: QMTQSPSSLSASVGDRVTITCKTSQDINKYMAWYQQTPGKAPRLLIHYTSALQPGIPSRFSGSGSGRDYTFTISSLQPEDIATYYCLQYDNLWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.2531
-
Maximal score value
-
1.6711
-
Average score
-
-0.9028
-
Total score value
-
-187.7865
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 3 |
Q |
L |
-1.2979 |
|
| 4 |
M |
L |
-1.1924 |
|
| 5 |
T |
L |
-1.0522 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.6689 |
|
| 8 |
P |
L |
-0.7029 |
|
| 9 |
S |
L |
-1.0134 |
|
| 10 |
S |
L |
-1.1077 |
|
| 11 |
L |
L |
-0.7883 |
|
| 12 |
S |
L |
-1.2709 |
|
| 13 |
A |
L |
-1.1813 |
|
| 14 |
S |
L |
-1.0104 |
|
| 15 |
V |
L |
0.0041 |
|
| 16 |
G |
L |
-0.8027 |
|
| 17 |
D |
L |
-2.0007 |
|
| 18 |
R |
L |
-2.4531 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6778 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7445 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
K |
L |
-2.9719 |
|
| 25 |
T |
L |
0.0000 |
|
| 26 |
S |
L |
-2.2691 |
|
| 27 |
Q |
L |
-3.2034 |
|
| 28 |
D |
L |
-3.9255 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
N |
L |
-2.9322 |
|
| 31 |
K |
L |
-2.5717 |
|
| 32 |
Y |
L |
-0.7688 |
|
| 33 |
M |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.1166 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.4000 |
|
| 39 |
T |
L |
-1.5867 |
|
| 40 |
P |
L |
-1.5007 |
|
| 41 |
G |
L |
-1.6260 |
|
| 42 |
K |
L |
-2.2669 |
|
| 43 |
A |
L |
-1.4559 |
|
| 44 |
P |
L |
-1.4171 |
|
| 45 |
R |
L |
-1.7897 |
|
| 46 |
L |
L |
-0.4943 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
H |
L |
0.4558 |
|
| 50 |
Y |
L |
0.7126 |
|
| 51 |
T |
L |
0.0000 |
|
| 52 |
S |
L |
-0.0744 |
|
| 53 |
A |
L |
0.3408 |
|
| 54 |
L |
L |
0.3602 |
|
| 55 |
Q |
L |
-0.4785 |
|
| 56 |
P |
L |
-0.4493 |
|
| 57 |
G |
L |
-0.5352 |
|
| 58 |
I |
L |
-0.3301 |
|
| 59 |
P |
L |
-0.3271 |
|
| 60 |
S |
L |
-0.4404 |
|
| 61 |
R |
L |
-0.7881 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.2771 |
|
| 64 |
G |
L |
-0.0964 |
|
| 65 |
S |
L |
-0.6715 |
|
| 66 |
G |
L |
-1.6326 |
|
| 67 |
S |
L |
-2.3366 |
|
| 68 |
G |
L |
-3.1931 |
|
| 69 |
R |
L |
-4.2531 |
|
| 70 |
D |
L |
-3.3332 |
|
| 71 |
Y |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7065 |
|
| 73 |
F |
L |
0.0000 |
|
| 74 |
T |
L |
-0.5873 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3615 |
|
| 77 |
S |
L |
-1.1160 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.0355 |
|
| 80 |
P |
L |
-2.3942 |
|
| 81 |
E |
L |
-2.8381 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
I |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-0.9836 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0309 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
L |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Y |
L |
0.3660 |
|
| 92 |
D |
L |
-1.1640 |
|
| 93 |
N |
L |
-0.9267 |
|
| 94 |
L |
L |
1.0010 |
|
| 95 |
W |
L |
1.6711 |
|
| 96 |
T |
L |
1.0205 |
|
| 97 |
F |
L |
1.3645 |
|
| 98 |
G |
L |
-0.2757 |
|
| 99 |
Q |
L |
-1.1190 |
|
| 100 |
G |
L |
0.0000 |
|
| 101 |
T |
L |
0.0000 |
|
| 102 |
K |
L |
-2.1437 |
|
| 103 |
V |
L |
0.0000 |
|
| 104 |
E |
L |
-1.9551 |
|
| 105 |
I |
L |
0.0000 |
|
| 106 |
K |
L |
-1.6582 |
|
| 107 |
R |
L |
-1.2633 |
|
| 108 |
T |
L |
-0.1429 |
|
| 109 |
V |
L |
0.6405 |
|
| 110 |
A |
L |
0.0754 |
|
| 111 |
A |
L |
-0.2159 |
|
| 112 |
P |
L |
0.0000 |
|
| 113 |
S |
L |
-0.1857 |
|
| 114 |
V |
L |
0.0000 |
|
| 115 |
F |
L |
1.2186 |
|
| 116 |
I |
L |
1.3128 |
|
| 117 |
F |
L |
1.4980 |
|
| 118 |
P |
L |
-0.1820 |
|
| 119 |
P |
L |
-1.1017 |
|
| 120 |
S |
L |
-1.9856 |
|
| 121 |
D |
L |
-3.4458 |
|
| 122 |
E |
L |
-3.7362 |
|
| 123 |
Q |
L |
-2.7864 |
|
| 124 |
L |
L |
-2.6235 |
|
| 125 |
K |
L |
-3.3768 |
|
| 126 |
S |
L |
-2.1128 |
|
| 127 |
G |
L |
-1.4084 |
|
| 128 |
T |
L |
-1.3224 |
|
| 129 |
A |
L |
0.0000 |
|
| 130 |
S |
L |
-0.0161 |
|
| 131 |
V |
L |
0.0000 |
|
| 132 |
V |
L |
0.8939 |
|
| 133 |
C |
L |
0.0000 |
|
| 134 |
L |
L |
0.6754 |
|
| 135 |
L |
L |
0.0000 |
|
| 136 |
N |
L |
-0.7407 |
|
| 137 |
N |
L |
-1.7610 |
|
| 138 |
F |
L |
0.0000 |
|
| 139 |
Y |
L |
0.0000 |
|
| 140 |
P |
L |
-1.2667 |
|
| 141 |
R |
L |
-2.1224 |
|
| 142 |
E |
L |
-2.6465 |
|
| 143 |
A |
L |
-2.0522 |
|
| 144 |
K |
L |
-2.2134 |
|
| 145 |
V |
L |
-0.9151 |
|
| 146 |
Q |
L |
-0.4894 |
|
| 147 |
W |
L |
0.0000 |
|
| 148 |
K |
L |
-0.6086 |
|
| 149 |
V |
L |
0.0000 |
|
| 150 |
D |
L |
-1.9748 |
|
| 151 |
N |
L |
-1.3997 |
|
| 152 |
A |
L |
-0.3288 |
|
| 153 |
L |
L |
0.6840 |
|
| 154 |
Q |
L |
-0.2574 |
|
| 155 |
S |
L |
-0.6792 |
|
| 156 |
G |
L |
-1.0618 |
|
| 157 |
N |
L |
-1.0334 |
|
| 158 |
S |
L |
-1.5588 |
|
| 159 |
Q |
L |
-2.4035 |
|
| 160 |
E |
L |
-2.3496 |
|
| 161 |
S |
L |
-1.3498 |
|
| 162 |
V |
L |
-0.8210 |
|
| 163 |
T |
L |
-1.0170 |
|
| 164 |
E |
L |
-2.2690 |
|
| 165 |
Q |
L |
0.0000 |
|
| 166 |
D |
L |
-3.1239 |
|
| 167 |
S |
L |
-3.0224 |
|
| 168 |
K |
L |
-3.6077 |
|
| 169 |
D |
L |
-3.4599 |
|
| 170 |
S |
L |
0.0000 |
|
| 171 |
T |
L |
0.0000 |
|
| 172 |
Y |
L |
0.0000 |
|
| 173 |
S |
L |
-0.9752 |
|
| 174 |
L |
L |
0.0000 |
|
| 175 |
S |
L |
-0.6596 |
|
| 176 |
S |
L |
0.0000 |
|
| 177 |
T |
L |
-0.6558 |
|
| 178 |
L |
L |
0.0000 |
|
| 179 |
T |
L |
-0.3582 |
|
| 180 |
L |
L |
-0.4710 |
|
| 181 |
S |
L |
-1.1571 |
|
| 182 |
K |
L |
-2.2523 |
|
| 183 |
A |
L |
-2.1976 |
|
| 184 |
D |
L |
-3.0383 |
|
| 185 |
Y |
L |
0.0000 |
|
| 186 |
E |
L |
-3.7222 |
|
| 187 |
K |
L |
-3.7007 |
|
| 188 |
H |
L |
-3.2794 |
|
| 189 |
K |
L |
-3.4948 |
|
| 190 |
V |
L |
-2.2524 |
|
| 191 |
Y |
L |
0.0000 |
|
| 192 |
A |
L |
0.0000 |
|
| 193 |
C |
L |
0.0000 |
|
| 194 |
E |
L |
-0.4684 |
|
| 195 |
V |
L |
0.0000 |
|
| 196 |
T |
L |
-0.9472 |
|
| 197 |
H |
L |
0.0000 |
|
| 198 |
Q |
L |
-1.6044 |
|
| 199 |
G |
L |
-0.4161 |
|
| 200 |
L |
L |
-0.1494 |
|
| 201 |
S |
L |
-0.3700 |
|
| 202 |
S |
L |
-0.2807 |
|
| 203 |
P |
L |
-0.1141 |
|
| 204 |
V |
L |
0.3238 |
|
| 205 |
T |
L |
-0.2083 |
|
| 206 |
K |
L |
-0.3091 |
|
| 207 |
S |
L |
-0.4385 |
|
| 208 |
F |
L |
-0.9918 |
|
| 209 |
N |
L |
-2.5515 |
|
| 210 |
R |
L |
-3.1897 |
|