Project name: 4evn:A

Chain sequence(s)	A: QVQLVESGAEVKKPGSSVKVSCKASGGPFRSYAISWVRQAPGQGPEWMGGIIPIFGTTKYAPKFQGRVTITADDFAGTVYMELSSLRSEDTAMYYCAKHMGYQVRETMDVWGKGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7751
• Maximal score value: 3.1414
• Average score: -0.4454
• Total score value: -98.4384

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.4200
2	V	A	-0.9213
3	Q	A	-1.2200
4	L	A	0.0000
5	V	A	0.6861
6	E	A	0.0000
7	S	A	-0.4062
8	G	A	-0.4561
9	A	A	-0.4584
10	E	A	-0.8225
11	V	A	-0.4384
12	K	A	-1.4084
13	K	A	-2.1553
14	P	A	-2.0659
15	G	A	-1.5223
16	S	A	-1.1939
17	S	A	-1.2307
18	V	A	0.0000
19	K	A	-2.1152
20	V	A	0.0000
21	S	A	-0.5645
22	C	A	0.0000
23	K	A	-0.9260
24	A	A	0.0000
25	S	A	-0.7521
26	G	A	-0.8617
27	G	A	-0.4572
28	P	A	0.3599
29	F	A	1.9967
30	R	A	0.0000
31	S	A	0.9399
32	Y	A	1.1113
33	A	A	0.0000
34	I	A	0.0000
35	S	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	-0.4332
39	Q	A	-0.8929
40	A	A	-1.1307
41	P	A	-0.8915
42	G	A	-1.2306
43	Q	A	-1.6798
44	G	A	-1.3194
45	P	A	-0.9517
46	E	A	-0.7840
47	W	A	-0.1951
48	M	A	0.0000
49	G	A	0.0000
50	G	A	0.0000
51	I	A	0.0000
52	I	A	0.0000
52A	P	A	0.0000
53	I	A	3.1414
54	F	A	2.7613
55	G	A	1.2140
56	T	A	0.3501
57	T	A	-0.5872
58	K	A	-1.6583
59	Y	A	-1.2656
60	A	A	0.0000
61	P	A	-1.6469
62	K	A	-2.2506
63	F	A	0.0000
64	Q	A	-2.3015
65	G	A	-1.5405
66	R	A	-1.4794
67	V	A	0.0000
68	T	A	-1.0217
69	I	A	0.0000
70	T	A	-0.3387
71	A	A	-0.0331
72	D	A	-0.0466
73	D	A	0.7291
74	F	A	1.8390
75	A	A	0.6009
76	G	A	0.0000
77	T	A	-0.0967
78	V	A	0.0000
79	Y	A	-0.6482
80	M	A	0.0000
81	E	A	-1.5735
82	L	A	0.0000
82A	S	A	-1.2051
82B	S	A	-1.1517
82C	L	A	0.0000
83	R	A	-2.7751
84	S	A	-2.2224
85	E	A	-2.4486
86	D	A	0.0000
87	T	A	-0.9714
88	A	A	0.0000
89	M	A	0.0396
90	Y	A	0.0000
91	Y	A	0.1667
92	C	A	0.0000
93	A	A	0.0000
94	K	A	0.1992
95	H	A	0.0000
96	M	A	0.6645
97	G	A	0.4246
98	Y	A	1.1248
99	Q	A	-0.2231
100	V	A	-0.8277
101	R	A	-1.8769
102	E	A	-1.2995
103	T	A	-0.6225
104	M	A	-0.1487
105	D	A	-0.2816
106	V	A	0.1760
107	W	A	0.3125
108	G	A	0.0000
109	K	A	-1.1544
110	G	A	0.0000
111	T	A	0.0000
112	T	A	-0.0518
113	V	A	0.0000
114	T	A	-0.7560
115	V	A	0.0000
116	S	A	-1.1763
117	S	A	-1.0846
118	A	A	-0.6801
119	S	A	-0.7460
120	T	A	-0.7065
121	K	A	-1.3787
122	G	A	-1.4647
123	P	A	-0.5696
124	S	A	-0.0103
125	V	A	0.0000
126	F	A	1.0842
127	P	A	0.0862
128	L	A	0.4558
129	A	A	-0.6203
130	P	A	0.0000
131	S	A	-0.9705
132	S	A	-1.1662
133	K	A	-1.9193
134	S	A	-1.1045
135	T	A	-1.0073
136	S	A	-0.9684
137	G	A	-0.8561
138	G	A	-0.9104
139	T	A	-0.6742
140	A	A	0.0000
141	A	A	-0.1265
142	L	A	0.0000
143	G	A	0.0000
144	C	A	0.0000
145	L	A	0.7852
146	V	A	0.0000
147	K	A	-0.0557
148	D	A	-0.4376
149	Y	A	0.0000
150	F	A	0.0000
151	P	A	0.0000
152	E	A	-0.8477
153	P	A	-0.8717
154	V	A	-0.6858
155	T	A	-0.6154
156	V	A	-0.3726
158	S	A	-0.4686
159	W	A	0.0000
164	N	A	-0.8684
165	S	A	-0.7178
166	G	A	-0.5431
167	A	A	-0.2181
168	L	A	0.0836
169	T	A	-0.2028
170	S	A	-0.2988
171	G	A	-0.3434
173	V	A	0.1050
174	H	A	-0.3620
175	T	A	0.3198
176	F	A	1.2392
177	P	A	0.8188
178	A	A	1.3114
179	V	A	2.4946
180	L	A	2.1462
181	Q	A	0.6277
182	S	A	0.0431
183	S	A	-0.2505
184	G	A	0.1696
185	L	A	0.2033
186	Y	A	0.7055
187	S	A	0.0000
188	L	A	0.0000
189	S	A	0.7663
190	S	A	0.0000
191	V	A	0.4540
192	V	A	0.0000
193	T	A	-0.2136
194	V	A	0.0000
195	P	A	-0.6780
196	S	A	-0.6643
197	S	A	-0.6114
198	S	A	-0.6538
199	L	A	-0.8837
200	G	A	-1.0888
201	T	A	-0.7199
204	Q	A	-1.2795
206	T	A	-1.1720
207	Y	A	0.0000
208	I	A	-1.4642
209	C	A	0.0000
210	N	A	-1.5932
211	V	A	0.0000
212	N	A	-1.8662
213	H	A	0.0000
214	K	A	-2.7540
215	P	A	-1.6437
216	S	A	-1.8395
217	N	A	-2.5780
218	T	A	-2.2311
219	K	A	-2.6868
220	V	A	-1.5145
221	D	A	-2.6982
222	K	A	-2.2941
223	R	A	-2.6657
224	V	A	0.0000
227	E	A	-2.5064
228	P	A	-1.1644