Project name: 6co3:H
Status: done
submitted: 2019-03-20 16:21:02, status changed: 2019-03-20 17:34:57
Settings
|
Chain sequence(s)
|
H: QVQLVESGGGVVQPGRSLRLSCAASGFAFSSYGMHWVRQAPGKGLEWVAVIWFDGTKKYYTDSVKGRFTISRDNSKNTLYLQMNTLRAEDTAVYYCARDRGIGARRGPYYMDVWGKGTTVTVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.9193
-
Maximal score value
-
2.4944
-
Average score
-
-0.5652
-
Total score value
-
-123.2148
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
H |
-1.2201 |
|
| 2 |
V |
H |
-0.4135 |
|
| 3 |
Q |
H |
-0.6409 |
|
| 4 |
L |
H |
0.0000 |
|
| 5 |
V |
H |
0.4535 |
|
| 6 |
E |
H |
0.0000 |
|
| 7 |
S |
H |
-0.5246 |
|
| 8 |
G |
H |
-0.8211 |
|
| 9 |
G |
H |
-0.3628 |
|
| 10 |
G |
H |
0.2538 |
|
| 11 |
V |
H |
0.8103 |
|
| 12 |
V |
H |
0.0000 |
|
| 13 |
Q |
H |
-1.4647 |
|
| 14 |
P |
H |
-1.8301 |
|
| 15 |
G |
H |
-1.8406 |
|
| 16 |
R |
H |
-2.6137 |
|
| 17 |
S |
H |
-1.9493 |
|
| 18 |
L |
H |
-1.1585 |
|
| 19 |
R |
H |
-1.5072 |
|
| 20 |
L |
H |
0.0000 |
|
| 21 |
S |
H |
-0.3277 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
A |
H |
-0.2037 |
|
| 24 |
A |
H |
0.0000 |
|
| 25 |
S |
H |
-0.7382 |
|
| 26 |
G |
H |
-0.7640 |
|
| 27 |
F |
H |
-0.1437 |
|
| 28 |
A |
H |
0.0268 |
|
| 29 |
F |
H |
0.0000 |
|
| 30 |
S |
H |
-0.8452 |
|
| 31 |
S |
H |
-0.5480 |
|
| 32 |
Y |
H |
-0.6454 |
|
| 33 |
G |
H |
-0.7631 |
|
| 34 |
M |
H |
0.0000 |
|
| 35 |
H |
H |
0.0000 |
|
| 36 |
W |
H |
0.0000 |
|
| 37 |
V |
H |
0.0000 |
|
| 38 |
R |
H |
0.0000 |
|
| 39 |
Q |
H |
-0.5815 |
|
| 40 |
A |
H |
-1.1879 |
|
| 41 |
P |
H |
-0.9146 |
|
| 42 |
G |
H |
-1.4530 |
|
| 43 |
K |
H |
-2.1214 |
|
| 44 |
G |
H |
-1.0119 |
|
| 45 |
L |
H |
0.4643 |
|
| 46 |
E |
H |
-0.4334 |
|
| 47 |
W |
H |
0.2897 |
|
| 48 |
V |
H |
0.0000 |
|
| 49 |
A |
H |
0.0000 |
|
| 50 |
V |
H |
0.0000 |
|
| 51 |
I |
H |
0.0000 |
|
| 52 |
W |
H |
0.0000 |
|
| 53 |
F |
H |
-0.8669 |
|
| 54 |
D |
H |
-1.4683 |
|
| 55 |
G |
H |
-1.3594 |
|
| 56 |
T |
H |
-1.2698 |
|
| 57 |
K |
H |
-1.7807 |
|
| 58 |
K |
H |
-1.0499 |
|
| 59 |
Y |
H |
-0.2474 |
|
| 60 |
Y |
H |
-0.5768 |
|
| 61 |
T |
H |
-1.1086 |
|
| 62 |
D |
H |
-2.3539 |
|
| 63 |
S |
H |
-1.8252 |
|
| 64 |
V |
H |
0.0000 |
|
| 65 |
K |
H |
-2.4992 |
|
| 66 |
G |
H |
-1.7835 |
|
| 67 |
R |
H |
-1.4147 |
|
| 68 |
F |
H |
0.0000 |
|
| 69 |
T |
H |
-0.7774 |
|
| 70 |
I |
H |
0.0000 |
|
| 71 |
S |
H |
-0.4895 |
|
| 72 |
R |
H |
-1.1622 |
|
| 73 |
D |
H |
-1.9090 |
|
| 74 |
N |
H |
-1.8882 |
|
| 75 |
S |
H |
-1.7028 |
|
| 76 |
K |
H |
-2.4887 |
|
| 77 |
N |
H |
-1.8723 |
|
| 78 |
T |
H |
-1.1402 |
|
| 79 |
L |
H |
0.0000 |
|
| 80 |
Y |
H |
-0.4019 |
|
| 81 |
L |
H |
0.0000 |
|
| 82 |
Q |
H |
-0.9623 |
|
| 83 |
M |
H |
0.0000 |
|
| 84 |
N |
H |
-1.8829 |
|
| 85 |
T |
H |
-1.6313 |
|
| 86 |
L |
H |
0.0000 |
|
| 87 |
R |
H |
-2.4216 |
|
| 88 |
A |
H |
-1.6420 |
|
| 89 |
E |
H |
-2.2423 |
|
| 90 |
D |
H |
0.0000 |
|
| 91 |
T |
H |
-0.7208 |
|
| 92 |
A |
H |
0.0000 |
|
| 93 |
V |
H |
0.2380 |
|
| 94 |
Y |
H |
0.0000 |
|
| 95 |
Y |
H |
0.2281 |
|
| 96 |
C |
H |
0.0000 |
|
| 97 |
A |
H |
0.0000 |
|
| 98 |
R |
H |
-0.4125 |
|
| 99 |
D |
H |
0.0000 |
|
| 100 |
R |
H |
-1.1712 |
|
| 101 |
G |
H |
-0.2198 |
|
| 102 |
I |
H |
0.6380 |
|
| 103 |
G |
H |
-0.4451 |
|
| 104 |
A |
H |
-1.0303 |
|
| 105 |
R |
H |
-2.1378 |
|
| 106 |
R |
H |
-1.4581 |
|
| 107 |
G |
H |
0.0000 |
|
| 108 |
P |
H |
0.1874 |
|
| 109 |
Y |
H |
1.2943 |
|
| 110 |
Y |
H |
0.8977 |
|
| 111 |
M |
H |
-0.0185 |
|
| 112 |
D |
H |
-0.9822 |
|
| 113 |
V |
H |
-0.2725 |
|
| 114 |
W |
H |
-0.0181 |
|
| 115 |
G |
H |
-0.3894 |
|
| 116 |
K |
H |
-1.3791 |
|
| 117 |
G |
H |
0.0000 |
|
| 118 |
T |
H |
-0.2879 |
|
| 119 |
T |
H |
0.0800 |
|
| 120 |
V |
H |
0.0000 |
|
| 121 |
T |
H |
0.0000 |
|
| 122 |
V |
H |
0.0000 |
|
| 123 |
S |
H |
-0.6058 |
|
| 124 |
S |
H |
-0.4684 |
|
| 125 |
A |
H |
-0.3677 |
|
| 126 |
S |
H |
-0.4759 |
|
| 127 |
T |
H |
-0.7155 |
|
| 128 |
K |
H |
-1.2148 |
|
| 129 |
G |
H |
-1.4148 |
|
| 130 |
P |
H |
0.0000 |
|
| 131 |
S |
H |
-0.1409 |
|
| 132 |
V |
H |
0.0000 |
|
| 133 |
F |
H |
0.7445 |
|
| 134 |
P |
H |
0.0399 |
|
| 135 |
L |
H |
0.5551 |
|
| 136 |
A |
H |
-0.8458 |
|
| 137 |
P |
H |
0.0000 |
|
| 138 |
S |
H |
-0.7341 |
|
| 146 |
T |
H |
-0.3005 |
|
| 147 |
A |
H |
0.0000 |
|
| 148 |
A |
H |
0.0844 |
|
| 149 |
L |
H |
0.0000 |
|
| 150 |
G |
H |
0.0000 |
|
| 151 |
C |
H |
0.0000 |
|
| 152 |
L |
H |
0.6883 |
|
| 153 |
V |
H |
0.0000 |
|
| 154 |
K |
H |
-0.3152 |
|
| 155 |
D |
H |
-0.6033 |
|
| 156 |
Y |
H |
0.0000 |
|
| 157 |
F |
H |
0.0000 |
|
| 158 |
P |
H |
-0.6410 |
|
| 159 |
E |
H |
-0.6636 |
|
| 160 |
P |
H |
-0.9099 |
|
| 161 |
V |
H |
-0.7258 |
|
| 162 |
T |
H |
-0.5819 |
|
| 163 |
V |
H |
-0.1525 |
|
| 164 |
S |
H |
-0.4306 |
|
| 165 |
W |
H |
0.0000 |
|
| 166 |
N |
H |
-0.7677 |
|
| 167 |
S |
H |
-0.6490 |
|
| 168 |
G |
H |
-0.4454 |
|
| 169 |
A |
H |
-0.1947 |
|
| 170 |
L |
H |
0.0115 |
|
| 171 |
T |
H |
-0.2755 |
|
| 172 |
S |
H |
-0.3714 |
|
| 173 |
G |
H |
-0.4449 |
|
| 174 |
V |
H |
0.0413 |
|
| 175 |
H |
H |
-0.4363 |
|
| 176 |
T |
H |
0.1910 |
|
| 177 |
F |
H |
0.9516 |
|
| 178 |
P |
H |
0.6359 |
|
| 179 |
A |
H |
1.2195 |
|
| 180 |
V |
H |
2.4944 |
|
| 181 |
L |
H |
2.1751 |
|
| 182 |
Q |
H |
0.7611 |
|
| 183 |
S |
H |
0.1412 |
|
| 184 |
S |
H |
-0.1497 |
|
| 185 |
G |
H |
0.2786 |
|
| 186 |
L |
H |
0.2497 |
|
| 187 |
Y |
H |
0.7492 |
|
| 188 |
S |
H |
0.0000 |
|
| 189 |
L |
H |
0.0000 |
|
| 190 |
S |
H |
0.6361 |
|
| 191 |
S |
H |
0.0000 |
|
| 192 |
V |
H |
0.4966 |
|
| 193 |
V |
H |
0.0000 |
|
| 194 |
T |
H |
-0.2041 |
|
| 195 |
V |
H |
0.0000 |
|
| 196 |
P |
H |
-0.4301 |
|
| 197 |
S |
H |
-0.5185 |
|
| 198 |
S |
H |
-0.6040 |
|
| 199 |
S |
H |
-0.6589 |
|
| 200 |
L |
H |
-0.9001 |
|
| 201 |
G |
H |
-0.9840 |
|
| 202 |
T |
H |
-0.7708 |
|
| 203 |
Q |
H |
-1.2999 |
|
| 204 |
T |
H |
-1.2424 |
|
| 205 |
Y |
H |
0.0000 |
|
| 206 |
I |
H |
-1.5115 |
|
| 207 |
C |
H |
0.0000 |
|
| 208 |
N |
H |
-1.5376 |
|
| 209 |
V |
H |
0.0000 |
|
| 210 |
N |
H |
-1.7788 |
|
| 211 |
H |
H |
0.0000 |
|
| 212 |
K |
H |
-2.7114 |
|
| 213 |
P |
H |
-1.6674 |
|
| 214 |
S |
H |
-1.8151 |
|
| 215 |
N |
H |
-2.5422 |
|
| 216 |
T |
H |
-2.0262 |
|
| 217 |
K |
H |
-2.5912 |
|
| 218 |
V |
H |
-1.6315 |
|
| 219 |
D |
H |
-2.6510 |
|
| 220 |
K |
H |
-2.1269 |
|
| 221 |
R |
H |
-2.6975 |
|
| 222 |
V |
H |
0.0000 |
|
| 223 |
E |
H |
-2.9193 |
|
| 224 |
P |
H |
-1.8785 |
|
| 225 |
K |
H |
-2.2882 |
|