Project name: 4irz:H

Chain sequence(s)	H: QVQQLVQSGAEVKKPGASVKVSCKASGFNIKDTYIHWVRQAPGQRLEWMGRIDPANGYTKYDPKFQGRVTITADTSASTAYMELSSLRSEDEAVYYCCAREGYYGNYGVYAMDYWGQGTLVTVSSASTKGPSVFPLAPCSSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2042
• Maximal score value: 2.3529
• Average score: -0.5603
• Total score value: -121.5786

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.4000
2	V	H	-0.7453
3	Q	H	-1.1137
4	L	H	0.0000
5	V	H	0.1231
6	Q	H	0.0000
7	S	H	-0.8023
8	G	H	-1.2296
9	A	H	-1.3401
10	E	H	-2.2183
11	V	H	-1.4045
12	K	H	-2.0417
13	K	H	-2.4973
14	P	H	-2.3209
15	G	H	-1.6579
16	A	H	-1.2876
17	S	H	-1.5139
18	V	H	0.0000
19	K	H	-2.1053
20	V	H	0.0000
21	S	H	-0.6755
22	C	H	0.0000
23	K	H	-1.2377
24	A	H	0.0000
25	S	H	-1.0037
26	G	H	-1.0315
27	F	H	-1.0491
28	N	H	-1.9842
29	I	H	0.0000
30	K	H	-2.4604
31	D	H	-2.3550
32	T	H	0.0000
33	Y	H	-0.2016
34	I	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.4812
39	Q	H	-1.0416
40	A	H	-1.4781
41	P	H	-1.3472
42	G	H	-1.5192
43	Q	H	-2.3706
44	R	H	-2.3660
45	L	H	-0.6779
46	E	H	-0.5949
47	W	H	0.1156
48	M	H	0.0000
49	G	H	0.0000
50	R	H	-0.8256
51	I	H	0.0000
52	D	H	-0.9782
53	P	H	0.0000
54	A	H	-1.2672
55	N	H	-1.1797
56	G	H	-0.5703
57	Y	H	0.3076
58	T	H	-0.5099
59	K	H	-1.6220
60	Y	H	-1.6067
61	D	H	-1.7001
62	P	H	-1.8775
63	K	H	-2.4270
64	F	H	0.0000
65	Q	H	-2.4752
66	G	H	-1.6238
67	R	H	-1.5621
68	V	H	0.0000
69	T	H	-1.1842
70	I	H	0.0000
71	T	H	-0.2521
72	A	H	-0.8082
73	D	H	-1.0592
74	T	H	-0.9021
75	S	H	-0.4656
76	A	H	-0.5988
77	S	H	-1.0603
78	T	H	-0.6833
79	A	H	0.0000
80	Y	H	-0.6578
81	M	H	0.0000
82	E	H	-1.8182
83	L	H	0.0000
84	S	H	-1.3155
85	S	H	-1.3125
86	L	H	0.0000
87	R	H	-3.2042
88	S	H	-2.5946
89	E	H	-2.7663
90	D	H	0.0000
91	E	H	-1.6569
92	A	H	0.0000
93	V	H	0.0994
94	Y	H	0.0000
95	Y	H	0.2690
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.2174
99	E	H	0.4727
100	G	H	0.0000
101	Y	H	1.8239
102	Y	H	1.5287
103	G	H	0.2618
104	N	H	-0.3818
105	Y	H	1.2722
106	G	H	0.9799
107	V	H	2.3529
108	Y	H	2.1719
109	A	H	1.2336
110	M	H	0.7360
111	D	H	0.4859
112	Y	H	0.6962
113	W	H	0.6220
114	G	H	0.0000
115	Q	H	-0.8050
116	G	H	-0.2872
117	T	H	0.0000
118	L	H	-0.4705
119	V	H	0.0000
120	T	H	0.0000
121	V	H	0.0000
122	S	H	-1.4391
123	S	H	-1.0355
124	A	H	-0.6259
125	S	H	-0.7118
126	T	H	-0.8066
127	K	H	-1.1318
128	G	H	-1.5562
129	P	H	-0.8944
130	S	H	-0.3626
131	V	H	0.0000
132	F	H	1.5000
133	P	H	0.3004
134	L	H	0.5032
135	A	H	-0.2612
136	P	H	-0.0669
137	C	H	0.5955
138	S	H	0.1028
144	S	H	-0.3742
145	T	H	-0.2393
146	A	H	-0.0905
147	A	H	0.1964
148	L	H	0.0000
149	G	H	0.0000
150	C	H	0.0000
151	L	H	0.7013
152	V	H	0.0000
153	K	H	-0.9216
154	D	H	-1.5793
155	Y	H	0.0000
156	F	H	0.0000
157	P	H	0.0000
158	E	H	-0.8571
159	P	H	-0.8634
160	V	H	-0.5951
161	T	H	-0.5609
162	V	H	-0.3201
163	S	H	-0.4088
164	W	H	0.0000
165	N	H	-0.9019
166	S	H	-0.6198
167	G	H	-0.5460
168	A	H	-0.2407
169	L	H	-0.1084
170	T	H	-0.3014
171	S	H	-0.3374
172	G	H	-0.3893
173	V	H	0.1516
174	H	H	-0.2150
175	T	H	0.4764
176	F	H	1.3779
177	P	H	0.9358
178	A	H	1.1862
179	V	H	2.2824
180	L	H	1.5517
181	Q	H	-0.4188
182	S	H	-0.5896
183	S	H	-0.6343
184	G	H	-0.2206
185	L	H	-0.2702
186	Y	H	0.3481
187	S	H	0.2277
188	L	H	0.0000
189	S	H	0.7327
190	S	H	0.0000
191	V	H	0.5990
192	V	H	0.0000
193	T	H	-0.1015
194	V	H	-0.0531
195	P	H	-0.2963
196	S	H	-0.2996
197	S	H	-0.5191
198	S	H	-0.6043
199	L	H	-0.5404
200	G	H	-0.9696
201	T	H	-0.8901
202	K	H	-1.4751
203	T	H	-1.4533
204	Y	H	0.0000
205	T	H	-1.8154
206	C	H	0.0000
207	N	H	-1.4807
208	V	H	0.0000
209	D	H	-1.9133
210	H	H	0.0000
211	K	H	-3.0851
212	P	H	-2.0822
213	S	H	-2.0111
214	N	H	-2.4881
215	T	H	-2.1933
216	K	H	-2.6647
217	V	H	-1.7014
218	D	H	-2.1713
219	K	H	-1.8937
220	R	H	-2.6366
221	V	H	0.0000
222	E	H	-2.2191