Project name: 3iu3:L
Status: done
submitted: 2019-03-20 20:10:58, status changed: 2019-03-20 20:23:56
Settings
|
Chain sequence(s)
|
L: QIVSTQSPAIMSASPGEKVTMTCSASSSRSYMQWYQQKPGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCHQRSSYTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8881
-
Maximal score value
-
1.6783
-
Average score
-
-0.7522
-
Total score value
-
-156.4542
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
L |
-0.6349 |
|
| 2 |
I |
L |
0.3942 |
|
| 3 |
V |
L |
1.5718 |
|
| 4 |
S |
L |
0.0000 |
|
| 5 |
T |
L |
0.1429 |
|
| 6 |
Q |
L |
-0.4435 |
|
| 7 |
S |
L |
-0.2500 |
|
| 8 |
P |
L |
0.1421 |
|
| 9 |
A |
L |
0.4967 |
|
| 10 |
I |
L |
1.5349 |
|
| 11 |
M |
L |
0.5128 |
|
| 12 |
S |
L |
-0.5356 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-2.0395 |
|
| 15 |
P |
L |
-1.9996 |
|
| 16 |
G |
L |
-2.2711 |
|
| 17 |
E |
L |
-3.3804 |
|
| 18 |
K |
L |
-2.9294 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.5307 |
|
| 21 |
M |
L |
0.0000 |
|
| 22 |
T |
L |
-0.3332 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
S |
L |
-0.2001 |
|
| 25 |
A |
L |
0.0554 |
|
| 26 |
S |
L |
-0.0352 |
|
| 27 |
S |
L |
-0.3489 |
|
| 28 |
S |
L |
-0.6352 |
|
| 29 |
R |
L |
-0.8128 |
|
| 30 |
S |
L |
-0.4013 |
|
| 31 |
Y |
L |
0.2712 |
|
| 32 |
M |
L |
0.0000 |
|
| 33 |
Q |
L |
0.0000 |
|
| 34 |
W |
L |
0.0000 |
|
| 35 |
Y |
L |
-0.7275 |
|
| 36 |
Q |
L |
0.0000 |
|
| 37 |
Q |
L |
-1.5215 |
|
| 38 |
K |
L |
-1.5989 |
|
| 39 |
P |
L |
-1.1357 |
|
| 40 |
G |
L |
-0.8813 |
|
| 41 |
T |
L |
-1.0052 |
|
| 42 |
S |
L |
-1.0425 |
|
| 43 |
P |
L |
-1.6365 |
|
| 44 |
K |
L |
-2.5290 |
|
| 45 |
R |
L |
-2.0248 |
|
| 46 |
W |
L |
0.0000 |
|
| 47 |
I |
L |
0.0000 |
|
| 48 |
Y |
L |
0.2493 |
|
| 49 |
D |
L |
-0.0840 |
|
| 50 |
T |
L |
-0.1362 |
|
| 51 |
S |
L |
-0.5903 |
|
| 52 |
K |
L |
-0.9098 |
|
| 53 |
L |
L |
-0.2315 |
|
| 54 |
A |
L |
-0.5567 |
|
| 55 |
S |
L |
-0.5863 |
|
| 56 |
G |
L |
-0.4081 |
|
| 57 |
V |
L |
-0.3732 |
|
| 58 |
P |
L |
-0.1623 |
|
| 59 |
A |
L |
-0.1738 |
|
| 60 |
R |
L |
-0.8510 |
|
| 61 |
F |
L |
0.0000 |
|
| 62 |
S |
L |
-0.5086 |
|
| 63 |
G |
L |
-0.4744 |
|
| 64 |
S |
L |
-0.6252 |
|
| 65 |
G |
L |
-0.5794 |
|
| 66 |
S |
L |
-0.5641 |
|
| 67 |
G |
L |
-0.6531 |
|
| 68 |
T |
L |
-0.5880 |
|
| 69 |
S |
L |
-0.6205 |
|
| 70 |
Y |
L |
0.0000 |
|
| 71 |
S |
L |
-0.4086 |
|
| 72 |
L |
L |
0.0000 |
|
| 73 |
T |
L |
-0.5985 |
|
| 74 |
I |
L |
0.0000 |
|
| 75 |
S |
L |
-1.6547 |
|
| 76 |
S |
L |
-2.0605 |
|
| 77 |
M |
L |
0.0000 |
|
| 78 |
E |
L |
-2.3184 |
|
| 79 |
A |
L |
-1.7493 |
|
| 80 |
E |
L |
-2.2671 |
|
| 81 |
D |
L |
0.0000 |
|
| 82 |
A |
L |
-1.2098 |
|
| 83 |
A |
L |
0.0000 |
|
| 84 |
T |
L |
0.0000 |
|
| 85 |
Y |
L |
0.0000 |
|
| 86 |
Y |
L |
-0.1649 |
|
| 87 |
C |
L |
0.0000 |
|
| 88 |
H |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
R |
L |
-0.5905 |
|
| 91 |
S |
L |
-0.5278 |
|
| 92 |
S |
L |
0.2560 |
|
| 93 |
Y |
L |
1.1183 |
|
| 94 |
T |
L |
1.0960 |
|
| 95 |
F |
L |
1.5610 |
|
| 96 |
G |
L |
0.5559 |
|
| 97 |
G |
L |
-0.2316 |
|
| 98 |
G |
L |
-0.1092 |
|
| 99 |
T |
L |
0.0000 |
|
| 100 |
K |
L |
-0.6074 |
|
| 101 |
L |
L |
0.0000 |
|
| 102 |
E |
L |
-0.8632 |
|
| 103 |
I |
L |
-1.3596 |
|
| 104 |
K |
L |
-1.6287 |
|
| 105 |
R |
L |
-1.1117 |
|
| 106 |
T |
L |
-0.1101 |
|
| 107 |
V |
L |
0.6950 |
|
| 108 |
A |
L |
0.1586 |
|
| 109 |
A |
L |
-0.1052 |
|
| 110 |
P |
L |
0.0000 |
|
| 111 |
S |
L |
0.0018 |
|
| 112 |
V |
L |
0.3111 |
|
| 113 |
F |
L |
1.1712 |
|
| 114 |
I |
L |
1.2390 |
|
| 115 |
F |
L |
1.6783 |
|
| 116 |
P |
L |
-0.1377 |
|
| 117 |
P |
L |
-0.7650 |
|
| 118 |
S |
L |
-1.7241 |
|
| 119 |
D |
L |
-3.2246 |
|
| 120 |
E |
L |
-3.4456 |
|
| 121 |
Q |
L |
-2.4879 |
|
| 122 |
L |
L |
-2.2862 |
|
| 123 |
K |
L |
-2.9983 |
|
| 124 |
S |
L |
-1.9054 |
|
| 125 |
G |
L |
-1.2614 |
|
| 126 |
T |
L |
-1.0377 |
|
| 127 |
A |
L |
0.0000 |
|
| 128 |
S |
L |
0.0987 |
|
| 129 |
V |
L |
0.0000 |
|
| 130 |
V |
L |
0.8646 |
|
| 131 |
C |
L |
0.0000 |
|
| 132 |
L |
L |
0.6466 |
|
| 133 |
L |
L |
0.0000 |
|
| 134 |
N |
L |
-0.5135 |
|
| 135 |
N |
L |
-1.2699 |
|
| 136 |
F |
L |
0.0000 |
|
| 137 |
Y |
L |
0.0000 |
|
| 138 |
P |
L |
-1.7268 |
|
| 139 |
R |
L |
-3.1414 |
|
| 140 |
E |
L |
-3.1913 |
|
| 141 |
A |
L |
-2.2895 |
|
| 142 |
K |
L |
-2.3645 |
|
| 143 |
V |
L |
-1.0755 |
|
| 144 |
Q |
L |
-0.7351 |
|
| 145 |
W |
L |
0.0000 |
|
| 146 |
K |
L |
-0.6541 |
|
| 147 |
V |
L |
0.0000 |
|
| 148 |
D |
L |
-2.0987 |
|
| 149 |
N |
L |
-1.4389 |
|
| 150 |
A |
L |
-0.3884 |
|
| 151 |
L |
L |
0.4392 |
|
| 152 |
Q |
L |
-0.1896 |
|
| 153 |
S |
L |
-0.6008 |
|
| 154 |
G |
L |
-1.0283 |
|
| 155 |
N |
L |
-0.9469 |
|
| 156 |
S |
L |
-1.4441 |
|
| 157 |
Q |
L |
-2.3666 |
|
| 158 |
E |
L |
-2.3169 |
|
| 159 |
S |
L |
-1.0969 |
|
| 160 |
V |
L |
-0.7290 |
|
| 161 |
T |
L |
-1.3096 |
|
| 162 |
E |
L |
-2.4195 |
|
| 163 |
Q |
L |
-2.3204 |
|
| 164 |
D |
L |
-2.5939 |
|
| 165 |
S |
L |
-2.2256 |
|
| 166 |
K |
L |
-2.5163 |
|
| 167 |
D |
L |
-2.1244 |
|
| 168 |
S |
L |
-2.1009 |
|
| 169 |
T |
L |
0.0000 |
|
| 170 |
Y |
L |
0.0000 |
|
| 171 |
S |
L |
-1.0217 |
|
| 172 |
L |
L |
0.0000 |
|
| 173 |
S |
L |
-0.4083 |
|
| 174 |
S |
L |
0.0000 |
|
| 175 |
T |
L |
-0.5491 |
|
| 176 |
L |
L |
0.0000 |
|
| 177 |
T |
L |
-0.4256 |
|
| 178 |
L |
L |
-0.5314 |
|
| 179 |
S |
L |
-0.9715 |
|
| 180 |
K |
L |
-2.0334 |
|
| 181 |
A |
L |
-1.8183 |
|
| 182 |
D |
L |
-2.3838 |
|
| 183 |
Y |
L |
0.0000 |
|
| 184 |
E |
L |
-3.8881 |
|
| 185 |
K |
L |
-3.8285 |
|
| 186 |
H |
L |
-3.4000 |
|
| 187 |
K |
L |
-3.6388 |
|
| 188 |
V |
L |
-1.8505 |
|
| 189 |
Y |
L |
0.0000 |
|
| 190 |
A |
L |
0.0000 |
|
| 191 |
C |
L |
0.0000 |
|
| 192 |
E |
L |
-0.8679 |
|
| 193 |
V |
L |
0.0000 |
|
| 194 |
T |
L |
-1.2117 |
|
| 195 |
H |
L |
0.0000 |
|
| 196 |
Q |
L |
-1.7254 |
|
| 197 |
G |
L |
-0.3655 |
|
| 198 |
L |
L |
-0.2744 |
|
| 199 |
S |
L |
-0.3310 |
|
| 200 |
S |
L |
-0.5977 |
|
| 201 |
P |
L |
-0.5496 |
|
| 202 |
V |
L |
-0.0337 |
|
| 203 |
T |
L |
-0.6544 |
|
| 204 |
K |
L |
-0.9115 |
|
| 205 |
S |
L |
-0.5368 |
|
| 206 |
F |
L |
-1.0636 |
|
| 207 |
N |
L |
-2.6187 |
|
| 208 |
R |
L |
-3.4971 |
|