Project name: 5u5m:A

Chain sequence(s)	A: DIQMTQSSPILLSASVGDRRVVTITCRASQDVNTAVAWYQQRTNGSPRLLIYSASFLYSSGVPSRFSGSRSGTDFTLLTISSLQPEDEADYYCCQQHHYTTPPTFGAGTKVEIKRTVAAPSSVFIFPPSDEEQLKSGTASVVCLLNNFYPREEAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACCEVTHQGLSSPVTKSFNRGEC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6018
• Maximal score value: 2.5562
• Average score: -0.7345
• Total score value: -157.1888

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-2.2958
2	I	A	0.0000
3	Q	A	-1.8319
4	M	A	0.0000
5	T	A	-0.6717
6	Q	A	0.0000
7	S	A	0.2159
8	P	A	0.8999
9	I	A	1.9445
10	L	A	1.1633
11	L	A	0.3026
12	S	A	-0.5536
13	A	A	-1.0439
14	S	A	-0.9230
15	V	A	-0.1621
16	G	A	-0.8644
17	D	A	-1.7310
18	R	A	-2.4021
19	V	A	0.0000
20	T	A	-0.5841
21	I	A	0.0000
22	T	A	-0.5803
23	C	A	0.0000
24	R	A	-2.9086
25	A	A	0.0000
26	S	A	-2.1933
27	Q	A	-2.8649
28	D	A	-2.8636
29	V	A	0.0000
30	N	A	-2.1989
31	T	A	-1.2745
32	A	A	-0.4854
33	V	A	0.0000
34	A	A	0.9052
35	W	A	0.0000
36	Y	A	0.0040
37	Q	A	0.0000
38	Q	A	-1.7933
39	R	A	-2.4246
40	T	A	-1.9999
41	N	A	-1.9901
42	G	A	-1.6680
43	S	A	-1.1992
44	P	A	-1.0542
45	R	A	-1.0526
46	L	A	0.3097
47	L	A	0.0000
48	I	A	0.0000
49	Y	A	1.7693
50	S	A	0.3080
51	A	A	0.0000
52	S	A	0.7464
53	F	A	2.5562
54	L	A	1.9772
55	Y	A	1.6448
56	S	A	0.4276
57	G	A	-0.2795
58	V	A	0.0000
59	P	A	-0.2390
60	S	A	-0.3453
61	R	A	-0.7978
62	F	A	0.0000
63	S	A	0.0664
64	G	A	-0.0571
65	S	A	-1.0102
66	R	A	-2.6807
67	S	A	-1.8553
68	G	A	-2.1053
69	T	A	-2.4572
70	D	A	-2.2488
71	F	A	0.0000
72	T	A	-0.9722
73	L	A	0.0000
74	T	A	-0.6215
75	I	A	0.0000
76	S	A	-1.5118
77	S	A	-1.2900
78	L	A	0.0000
79	Q	A	-1.0412
80	P	A	-1.3907
81	E	A	-1.7737
82	D	A	0.0000
83	E	A	-1.7790
84	A	A	0.0000
85	D	A	-1.2536
86	Y	A	0.0000
87	Y	A	0.2107
88	C	A	0.0000
89	Q	A	0.0000
90	Q	A	0.0000
91	H	A	-0.4975
92	Y	A	-0.0325
93	T	A	-0.4425
94	T	A	-0.5561
95	P	A	-0.5209
96	P	A	-0.4042
97	T	A	0.1219
98	F	A	1.5207
99	G	A	0.4059
100	A	A	0.4801
101	G	A	0.4124
102	T	A	0.0000
103	K	A	-0.9337
104	V	A	0.0000
105	E	A	-1.3321
106	I	A	0.0000
107	K	A	-1.4468
108	R	A	-0.9256
109	T	A	-0.1920
110	V	A	0.1821
111	A	A	0.0093
112	A	A	-0.2357
113	P	A	0.0000
114	S	A	-0.0599
115	V	A	0.0000
116	F	A	1.4883
117	I	A	1.3921
118	F	A	1.5048
119	P	A	-0.1088
120	P	A	0.0000
121	S	A	-1.7840
122	D	A	-3.2148
123	E	A	-3.3858
124	Q	A	-2.4927
125	L	A	-2.5974
126	K	A	-3.0609
127	S	A	-1.9933
128	G	A	-1.3784
129	T	A	-1.0489
130	A	A	0.0000
131	S	A	0.0387
132	V	A	0.0000
133	V	A	0.7537
134	C	A	0.0000
135	L	A	0.5532
136	L	A	0.0000
137	N	A	-0.5475
138	N	A	-1.2078
139	F	A	0.0000
140	Y	A	-1.1672
141	P	A	-1.6917
142	R	A	-2.9156
143	E	A	-3.1456
144	A	A	-2.3672
145	K	A	-2.5387
146	V	A	0.0000
147	Q	A	-0.7677
148	W	A	0.0000
149	K	A	-0.6183
150	V	A	0.0000
151	D	A	-2.0589
152	N	A	-1.5810
153	A	A	-0.2709
154	L	A	0.7537
155	Q	A	-0.0677
156	S	A	-0.3800
157	G	A	-0.9736
158	N	A	-0.9120
159	S	A	-1.3997
160	Q	A	-2.2760
161	E	A	-2.3902
162	S	A	-1.3981
163	V	A	-0.8898
164	T	A	-1.2692
165	E	A	-2.5406
166	Q	A	0.0000
167	D	A	-2.2348
168	S	A	-2.0638
169	K	A	-2.3609
170	D	A	-1.6197
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-0.9972
175	L	A	0.0000
176	S	A	-0.5162
177	S	A	0.0000
178	T	A	-0.6197
179	L	A	0.0000
180	T	A	-0.4886
181	L	A	-0.6795
182	S	A	-1.2813
183	K	A	-2.1861
184	A	A	-1.8928
185	D	A	-2.4690
186	Y	A	0.0000
187	E	A	-3.4008
188	K	A	-3.6018
189	H	A	-3.0304
190	K	A	-3.3664
191	V	A	-1.6671
192	Y	A	0.0000
193	A	A	0.0000
194	C	A	0.0000
195	E	A	-1.0241
196	V	A	0.0000
197	T	A	-1.3135
198	H	A	0.0000
199	Q	A	-1.7737
200	G	A	-0.4829
201	L	A	-0.2499
202	S	A	-0.4477
203	S	A	-0.4405
204	P	A	-0.5944
205	V	A	-0.0682
206	T	A	-0.3574
207	K	A	-0.1956
208	S	A	-0.2808
209	F	A	0.0000
210	N	A	-2.0162
211	R	A	-2.5381
212	G	A	-2.0152
213	E	A	-2.2013
214	C	A	-0.4374