Project name: 3bl2 modified

Chain sequence(s)	A: KSGTYWATLITAFLKTVSKVEELDCVDSAVLVDVSKIITLTQEFRRHYDSVYRADYGPALKNWKRDLSKLFTSLFVDVINSGRIVGFFDVGRYVCEEVLCPGSWTEDHELLNDCMTHFFIENNLMNHFPLE; C: TMENLSRRLKVTGDLFDIM
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3768
• Maximal score value: 1.7373
• Average score: -0.805
• Total score value: -120.7554

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
5	K	A	-2.0073
6	S	A	-0.9888
7	G	A	-0.9319
8	T	A	-0.3443
9	Y	A	-0.5669
10	W	A	0.0000
11	A	A	-0.2793
12	T	A	-0.1655
13	L	A	0.0000
14	I	A	0.0000
15	T	A	-0.7203
16	A	A	0.1679
17	F	A	0.0000
18	L	A	0.0000
19	K	A	-1.3785
20	T	A	-0.9981
21	V	A	0.0000
22	S	A	0.0000
23	K	A	-2.4074
24	V	A	-2.1149
25	E	A	-2.9427
26	E	A	-2.4672
27	L	A	-0.4598
28	D	A	-1.0089
29	C	A	0.1531
30	V	A	-0.0533
31	D	A	-1.0258
32	S	A	-0.1097
33	A	A	0.2254
34	V	A	0.0000
35	L	A	1.3657
36	V	A	1.4460
37	D	A	0.4359
38	V	A	0.0000
39	S	A	0.3652
40	K	A	-0.1437
41	I	A	0.0000
42	I	A	-0.4001
43	T	A	-0.7829
44	L	A	-0.9586
45	T	A	0.0000
46	Q	A	-2.3251
47	E	A	-2.9136
48	F	A	0.0000
49	R	A	-2.6133
50	R	A	-3.3768
51	H	A	-1.7256
52	Y	A	0.0000
53	D	A	-2.4954
54	S	A	-1.2810
55	V	A	-0.2924
56	Y	A	-1.0254
57	R	A	-2.1240
58	A	A	-1.4507
59	D	A	-1.5102
60	Y	A	0.0000
61	G	A	-1.0952
62	P	A	-1.0166
63	A	A	-1.3784
64	L	A	0.0000
65	K	A	-2.2792
66	N	A	-2.2756
67	W	A	0.0000
68	K	A	-2.5048
69	R	A	-3.1884
70	D	A	-2.6756
71	L	A	0.0000
72	S	A	-1.7179
73	K	A	-2.4644
74	L	A	0.0000
75	F	A	0.0000
76	T	A	-0.4312
77	S	A	-0.6958
78	L	A	0.0000
79	F	A	0.0000
80	V	A	1.2102
81	D	A	-0.3704
82	V	A	0.8045
83	I	A	0.0288
84	N	A	-0.6517
85	S	A	-0.9133
86	G	A	0.0000
87	R	A	0.0000
88	I	A	0.0000
89	V	A	0.0000
90	G	A	0.0000
91	F	A	0.0000
92	F	A	0.0000
93	D	A	0.0000
94	V	A	0.0000
95	G	A	0.0000
96	R	A	-0.7377
97	Y	A	0.0000
98	V	A	0.0000
99	C	A	0.0000
100	E	A	-1.6923
101	E	A	-1.6734
102	V	A	-0.2473
103	L	A	0.1027
104	C	A	0.1233
105	P	A	-1.0583
106	G	A	-1.5522
107	S	A	-1.0933
108	W	A	-1.2474
109	T	A	-1.1750
110	E	A	-2.4139
111	D	A	-1.8468
112	H	A	0.0000
113	E	A	-2.4785
114	L	A	-1.3761
115	L	A	0.0000
116	N	A	-1.5689
117	D	A	-1.8074
118	C	A	-1.0586
119	M	A	0.0000
120	T	A	-0.9333
121	H	A	-1.6230
122	F	A	-1.2355
123	F	A	0.0000
124	I	A	-1.1724
125	E	A	-2.3439
126	N	A	-2.0929
127	N	A	-2.2644
128	L	A	0.0000
129	M	A	-1.4982
130	N	A	-2.2284
131	H	A	-1.6477
132	F	A	0.0000
133	P	A	-1.4247
134	L	A	-0.9171
135	E	A	-1.8420
106	T	C	-1.3177
107	M	C	-2.1524
108	E	C	-3.2091
109	N	C	-2.9065
110	L	C	0.0000
111	S	C	0.0000
112	R	C	-2.9847
113	R	C	-1.9231
114	L	C	0.0000
115	K	C	-1.0074
116	V	C	-0.5047
117	T	C	0.0000
118	G	C	0.0000
119	D	C	-0.4727
120	L	C	0.6752
121	F	C	0.0586
122	D	C	-0.5609
123	I	C	1.7373
124	M	C	1.6825