Project name: 4gw5:A

Chain sequence(s)	A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.78
• Maximal score value: 1.8828
• Average score: -0.8514
• Total score value: -180.4975

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-1.4118
2	I	A	0.0000
3	L	A	0.7605
4	L	A	0.0000
5	T	A	-0.3181
6	Q	A	0.0838
7	S	A	0.1035
8	P	A	0.8201
9	V	A	1.8828
10	I	A	1.2781
11	L	A	0.5131
12	S	A	-0.4443
13	V	A	0.0000
14	S	A	-1.8323
15	P	A	-2.1712
16	G	A	-2.1547
17	E	A	-2.8829
18	R	A	-2.9735
19	V	A	0.0000
20	S	A	-0.6749
21	F	A	0.0000
22	S	A	-0.8955
23	C	A	0.0000
24	R	A	-2.6540
25	A	A	0.0000
26	S	A	-1.0663
27	Q	A	-1.6817
28	S	A	-1.6169
29	I	A	0.0000
30	G	A	-1.1226
31	T	A	-0.8009
32	N	A	-1.0012
33	I	A	0.0000
34	H	A	0.0000
35	W	A	0.0000
36	Y	A	-0.2470
37	Q	A	0.0000
38	Q	A	-1.8514
39	R	A	-3.1064
40	T	A	-2.1959
41	N	A	-2.1169
42	G	A	-1.7407
43	S	A	-1.2237
44	P	A	-1.1585
45	R	A	-0.9850
46	L	A	-0.1693
47	L	A	0.0000
48	I	A	0.0000
49	K	A	-0.8876
50	Y	A	-0.2713
51	A	A	0.0000
52	S	A	-1.1650
53	E	A	-1.9241
54	S	A	-1.0772
55	I	A	-0.4127
56	S	A	-0.2011
57	G	A	-0.3680
58	I	A	-0.1123
59	P	A	-0.2746
60	S	A	-0.5002
61	R	A	-1.0475
62	F	A	0.0000
63	S	A	-0.8501
64	G	A	-0.6989
65	S	A	-0.8120
66	G	A	-1.0959
67	S	A	-1.1607
68	G	A	-1.4563
69	T	A	-2.0978
70	D	A	-2.8893
71	F	A	0.0000
72	T	A	-0.9410
73	L	A	0.0000
74	S	A	-0.7976
75	I	A	0.0000
76	N	A	-2.1332
77	S	A	-2.2572
78	V	A	0.0000
79	E	A	-2.8272
80	S	A	-2.8677
81	E	A	-3.2874
82	D	A	0.0000
83	I	A	-2.0807
84	A	A	0.0000
85	D	A	-0.8657
86	Y	A	0.0000
87	Y	A	0.2112
88	C	A	0.0000
89	Q	A	0.2991
90	Q	A	0.0000
91	N	A	-1.3244
92	N	A	-1.6803
93	N	A	-1.2851
94	W	A	0.0537
95	P	A	-0.1549
96	T	A	-0.4343
97	T	A	0.3140
98	F	A	1.4258
99	G	A	0.6328
100	A	A	0.6367
101	G	A	0.3971
102	T	A	0.0000
103	K	A	-0.3722
104	L	A	0.0000
105	E	A	-1.0254
106	L	A	0.0000
107	K	A	-1.5657
108	R	A	-1.0935
109	T	A	-0.1409
110	V	A	0.2414
111	A	A	-0.1606
112	A	A	-0.2216
113	P	A	0.0000
114	S	A	-0.0768
115	V	A	0.4085
116	F	A	1.3975
117	I	A	1.3500
118	F	A	1.5453
119	P	A	-0.0478
120	P	A	-0.7038
121	S	A	-1.7925
122	D	A	-3.2228
123	E	A	-3.3992
124	Q	A	-2.4459
125	L	A	-2.5619
126	K	A	-2.9751
127	S	A	-1.8480
128	G	A	-1.3077
129	T	A	-1.1313
130	A	A	0.0000
131	S	A	0.0431
132	V	A	0.0000
133	V	A	0.7473
134	C	A	0.0000
135	L	A	0.5751
136	L	A	0.0000
137	N	A	-0.5408
138	N	A	-1.3345
139	F	A	0.0000
140	Y	A	-1.2033
141	P	A	-1.6497
142	R	A	-2.7207
143	E	A	-3.1350
144	A	A	-2.2715
145	K	A	-2.2940
146	V	A	-1.2004
147	Q	A	-0.8949
148	W	A	0.0000
149	K	A	-0.7675
150	V	A	0.0000
151	D	A	-2.0626
152	N	A	-1.5563
153	A	A	-0.3041
154	L	A	0.6463
155	Q	A	-0.1701
156	S	A	-0.4327
157	G	A	-1.0226
158	N	A	-1.0187
159	S	A	-1.4091
160	Q	A	-2.1857
161	E	A	-2.0982
162	S	A	-1.2138
163	V	A	-0.7168
164	T	A	-1.1636
165	E	A	-2.4791
166	Q	A	0.0000
167	D	A	-2.5926
168	S	A	-3.0340
169	K	A	-3.1283
170	D	A	-2.3506
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-0.9630
175	L	A	0.0000
176	S	A	-0.4101
177	S	A	0.0000
178	T	A	-0.5679
179	L	A	0.0000
180	T	A	-0.5395
181	L	A	-0.7535
182	S	A	-1.0870
183	K	A	-2.1224
184	A	A	-1.9979
185	D	A	-2.6715
186	Y	A	0.0000
187	E	A	-3.7405
188	K	A	-3.7800
189	H	A	-3.2458
190	K	A	-3.3161
191	V	A	-1.5996
192	Y	A	0.0000
193	A	A	0.0000
194	C	A	0.0000
195	E	A	-1.0937
196	V	A	0.0000
197	T	A	-1.2815
198	H	A	0.0000
199	Q	A	-1.7339
200	G	A	-0.4402
201	L	A	-0.2064
202	S	A	-0.4321
203	S	A	-0.4148
204	P	A	-0.6253
205	V	A	-0.1117
206	T	A	-0.3927
207	K	A	-0.2540
208	S	A	-0.3766
209	F	A	-0.7409
210	N	A	-2.1499
211	R	A	-2.4980
212	G	A	-1.5370