Project name: Cerrena#390832

Chain sequence(s)	A: AIGPVTDLHIVNQNLAPDGLNRPTVLAGGTFPGPLIRGNKGDNFKINVIDDLTEHSMLKATSIHWHGFFQKGTNWADGPAFVTQCPITSGNAFLYDFNVPDQAGTFWYHSHLSTQYCDGLRGAFVVYDPNDPNKQLYDVDNESTVITLADWYHALAQTVTGVAVSDATLINGLGRSATGPANAPLAVISVERNKRYRFRLVSISCDPNFIFSIDHHPMTVIEMDGVNTQSMTVDSIQIFAGQRYSFVMQANQPVGNYWIRAKPNVGNTTFLGGLNSAILRYVGAPDQEPTTDQTPNSTPLVEANLRPLVYTPVPGQPFPGGADIVRNLALGFNAGRFTINGASFTPPTVPVLLQILSGTHNAQDLLPAGSVIELEQNKVVEIVLPAAGAVGGPHPFHLHGHNFWVVRSAGQTTYNFNDAPIRDVVSIGGANDQVTIRFVTDNPGPWFLHCHIDWHLEAGFAVVFAEGINGTAAANPVPAAWNQLCPLYDALSPGD
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -1.9962
• Maximal score value: 2.09
• Average score: -0.1601
• Total score value: -79.2469

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
18	A	A	0.1783
19	I	A	0.5222
20	G	A	0.1008
21	P	A	0.2095
22	V	A	1.6627
23	T	A	-0.0174
24	D	A	-1.8266
25	L	A	0.0000
26	H	A	-0.5487
27	I	A	0.0000
28	V	A	0.1971
29	N	A	-0.3328
30	Q	A	-0.9639
31	N	A	-1.3287
32	L	A	0.2185
33	A	A	-0.0439
34	P	A	0.0000
35	D	A	0.0000
36	G	A	-0.2747
37	L	A	0.3086
38	N	A	-1.1579
39	R	A	0.0000
40	P	A	-0.2509
41	T	A	0.0000
42	V	A	0.0000
43	L	A	0.0000
44	A	A	0.0000
45	G	A	-0.4917
46	G	A	-0.2300
47	T	A	-0.0556
48	F	A	0.0000
49	P	A	-0.0341
50	G	A	0.0000
51	P	A	-0.0147
52	L	A	0.1704
53	I	A	0.0000
54	R	A	-0.4654
55	G	A	-0.2947
56	N	A	-1.0029
57	K	A	-1.0540
58	G	A	-0.6664
59	D	A	-0.6286
60	N	A	-0.7066
61	F	A	0.0000
62	K	A	-0.4475
63	I	A	0.0000
64	N	A	-0.4224
65	V	A	0.0000
66	I	A	0.2480
67	D	A	0.0000
68	D	A	-1.0194
69	L	A	0.0000
70	T	A	-0.1903
71	E	A	-0.8484
72	H	A	-1.0818
73	S	A	-0.2508
74	M	A	0.0000
75	L	A	0.1692
76	K	A	-0.1541
77	A	A	0.0000
78	T	A	0.0000
79	S	A	0.0000
80	I	A	0.0000
81	H	A	0.0000
82	W	A	0.0000
83	H	A	0.0000
84	G	A	-0.0457
85	F	A	0.0000
86	F	A	0.2695
87	Q	A	0.0000
88	K	A	-1.7284
89	G	A	-0.4654
90	T	A	-0.0395
91	N	A	0.0000
92	W	A	0.0000
93	A	A	0.0000
94	D	A	0.0000
95	G	A	0.0000
96	P	A	0.0000
97	A	A	0.0000
98	F	A	0.2269
99	V	A	0.0000
100	T	A	0.0000
101	Q	A	0.0000
102	C	A	0.0000
103	P	A	0.0000
104	I	A	0.0000
105	T	A	0.0000
106	S	A	-0.1509
107	G	A	-0.5787
108	N	A	-0.6222
109	A	A	-0.0112
110	F	A	0.0000
111	L	A	0.5510
112	Y	A	0.0000
113	D	A	-0.5741
114	F	A	0.0000
115	N	A	-0.9612
116	V	A	0.0000
117	P	A	-0.6467
118	D	A	-1.8585
119	Q	A	-0.4440
120	A	A	-0.0155
121	G	A	0.0000
122	T	A	0.0000
123	F	A	0.0000
124	W	A	0.0000
125	Y	A	0.0000
126	H	A	0.0000
127	S	A	0.0000
128	H	A	0.0000
129	L	A	0.0000
130	S	A	-0.1011
131	T	A	0.0000
132	Q	A	0.0000
133	Y	A	0.0000
134	C	A	0.0000
135	D	A	0.0000
136	G	A	0.0000
137	L	A	0.0000
138	R	A	0.0000
139	G	A	0.0000
140	A	A	0.0000
141	F	A	0.0000
142	V	A	0.0000
143	V	A	0.0000
144	Y	A	0.0322
145	D	A	-0.1991
146	P	A	-0.5203
147	N	A	-1.3196
148	D	A	0.0000
149	P	A	-0.1846
150	N	A	0.0000
151	K	A	-1.2771
152	Q	A	-1.2874
153	L	A	0.3580
154	Y	A	0.0000
155	D	A	-1.5601
156	V	A	-0.1210
157	D	A	-0.4213
158	N	A	-0.7009
159	E	A	-1.0726
160	S	A	-0.3713
161	T	A	0.0000
162	V	A	0.0000
163	I	A	0.0000
164	T	A	0.0000
165	L	A	0.0000
166	A	A	0.0000
167	D	A	0.0000
168	W	A	0.0000
169	Y	A	0.0000
170	H	A	-0.2242
171	A	A	0.0178
172	L	A	0.1622
173	A	A	0.0000
174	Q	A	-0.6150
175	T	A	-0.0947
176	V	A	0.4343
177	T	A	-0.0724
178	G	A	-0.1533
179	V	A	1.6881
180	A	A	0.6455
181	V	A	1.7155
182	S	A	0.1168
183	D	A	-0.9614
184	A	A	0.0000
185	T	A	0.0000
186	L	A	0.0000
187	I	A	0.0000
188	N	A	-0.5361
189	G	A	0.0000
190	L	A	0.3416
191	G	A	0.0000
192	R	A	-0.1854
193	S	A	-0.0774
194	A	A	0.0087
195	T	A	-0.1089
196	G	A	-0.2698
197	P	A	-0.1356
198	A	A	-0.1917
199	N	A	-1.2624
200	A	A	0.0000
201	P	A	-0.2549
202	L	A	0.0000
203	A	A	0.0000
204	V	A	0.8072
205	I	A	0.0000
206	S	A	-0.2129
207	V	A	0.0000
208	E	A	-1.4761
209	R	A	-1.6853
210	N	A	-1.6296
211	K	A	-1.0723
212	R	A	-0.7305
213	Y	A	0.0000
214	R	A	0.0000
215	F	A	0.0000
216	R	A	0.0000
217	L	A	0.0000
218	V	A	0.0000
219	S	A	0.0000
220	I	A	0.0000
221	S	A	0.0000
222	C	A	0.0000
223	D	A	-0.2590
224	P	A	0.0000
225	N	A	0.0000
226	F	A	0.0000
227	I	A	0.2229
228	F	A	0.0000
229	S	A	0.0000
230	I	A	0.0000
231	D	A	0.0000
232	H	A	-0.5354
233	H	A	0.0000
234	P	A	-0.2398
235	M	A	0.0000
236	T	A	-0.0250
237	V	A	0.0000
238	I	A	0.0000
239	E	A	0.0000
240	M	A	0.0000
241	D	A	0.0000
242	G	A	-0.0123
243	V	A	0.1947
244	N	A	-0.2750
245	T	A	0.0000
246	Q	A	-0.8790
247	S	A	-0.3544
248	M	A	0.0571
249	T	A	-0.0531
250	V	A	0.0000
251	D	A	-0.3495
252	S	A	0.0000
253	I	A	0.0000
254	Q	A	-0.5350
255	I	A	0.0000
256	F	A	0.0000
257	A	A	0.0000
258	G	A	0.0000
259	Q	A	0.0000
260	R	A	0.0000
261	Y	A	0.0000
262	S	A	0.0000
263	F	A	0.0000
264	V	A	0.0000
265	M	A	0.0000
266	Q	A	-1.0122
267	A	A	0.0000
268	N	A	-1.0612
269	Q	A	-0.4985
270	P	A	-0.1059
271	V	A	1.0284
272	G	A	0.1346
273	N	A	0.0000
274	Y	A	0.0000
275	W	A	0.1231
276	I	A	0.0000
277	R	A	0.0000
278	A	A	0.0000
279	K	A	-0.5731
280	P	A	0.0000
281	N	A	-0.5264
282	V	A	0.5957
283	G	A	-0.3547
284	N	A	-1.3257
285	T	A	-0.2666
286	T	A	-0.0010
287	F	A	0.5689
288	L	A	1.5171
289	G	A	-0.1861
290	G	A	0.0000
291	L	A	0.0000
292	N	A	0.0000
293	S	A	0.0000
294	A	A	0.0000
295	I	A	0.0000
296	L	A	0.0000
297	R	A	-0.2247
298	Y	A	0.0000
299	V	A	1.6881
300	G	A	-0.1429
301	A	A	-0.1312
302	P	A	-0.5785
303	D	A	-1.9962
304	Q	A	-1.3675
305	E	A	-1.0615
306	P	A	0.0000
307	T	A	-0.0730
308	T	A	-0.3552
309	D	A	-1.8959
310	Q	A	-0.9064
311	T	A	-0.2061
312	P	A	-0.3733
313	N	A	-0.6735
314	S	A	-0.3250
315	T	A	-0.1118
316	P	A	-0.1574
317	L	A	0.4641
318	V	A	1.7672
319	E	A	0.1232
320	A	A	-0.2552
321	N	A	-1.2708
322	L	A	0.0000
323	R	A	-0.4007
324	P	A	0.0000
325	L	A	0.6283
326	V	A	2.0900
327	Y	A	1.6361
328	T	A	0.1817
329	P	A	-0.2241
330	V	A	0.1350
331	P	A	-0.0525
332	G	A	-0.5534
333	Q	A	-1.3001
334	P	A	-0.0246
335	F	A	1.8681
336	P	A	0.0462
337	G	A	-0.3497
338	G	A	-0.2840
339	A	A	-0.3683
340	D	A	-1.7873
341	I	A	0.0000
342	V	A	0.6387
343	R	A	-0.6369
344	N	A	-1.3520
345	L	A	0.0000
346	A	A	-0.0696
347	L	A	0.0000
348	G	A	0.1095
349	F	A	0.9123
350	N	A	-1.0501
351	A	A	-0.2454
352	G	A	-0.7241
353	R	A	-1.8175
354	F	A	0.0000
355	T	A	0.0000
356	I	A	0.0000
357	N	A	-1.2132
358	G	A	-0.6709
359	A	A	-0.0889
360	S	A	-0.0658
361	F	A	0.0000
362	T	A	-0.1142
363	P	A	-0.2606
364	P	A	-0.0827
365	T	A	0.1092
366	V	A	0.9969
367	P	A	0.0000
368	V	A	0.0000
369	L	A	0.0000
370	L	A	0.3886
371	Q	A	0.0000
372	I	A	0.0000
373	L	A	0.3156
374	S	A	-0.2399
375	G	A	-0.5082
376	T	A	-0.1948
377	H	A	-0.7338
378	N	A	-1.3584
379	A	A	-0.4177
380	Q	A	-1.3511
381	D	A	-1.0895
382	L	A	0.0000
383	L	A	1.0566
384	P	A	0.2757
385	A	A	0.0854
386	G	A	-0.4558
387	S	A	0.0000
388	V	A	0.2495
389	I	A	0.1371
390	E	A	-0.7068
391	L	A	0.0000
392	E	A	-1.9565
393	Q	A	-1.4130
394	N	A	-1.5320
395	K	A	-0.7634
396	V	A	0.1982
397	V	A	0.0000
398	E	A	0.0000
399	I	A	0.0000
400	V	A	0.0268
401	L	A	0.0000
402	P	A	-0.1791
403	A	A	0.0000
404	A	A	0.0000
405	G	A	-0.4561
406	A	A	0.2438
407	V	A	1.6899
408	G	A	-0.1983
409	G	A	-0.3902
410	P	A	-0.1589
411	H	A	0.0000
412	P	A	0.0000
413	F	A	0.0000
414	H	A	0.0000
415	L	A	0.0000
416	H	A	0.0000
417	G	A	0.0000
418	H	A	0.0000
419	N	A	-0.3007
420	F	A	0.0000
421	W	A	0.1270
422	V	A	0.0000
423	V	A	0.0000
424	R	A	-0.2198
425	S	A	0.0000
426	A	A	-0.0734
427	G	A	-0.5050
428	Q	A	-0.3267
429	T	A	-0.1254
430	T	A	-0.0079
431	Y	A	0.3293
432	N	A	0.0303
433	F	A	0.6546
434	N	A	-1.2458
435	D	A	-1.0012
436	A	A	0.0000
437	P	A	0.0000
438	I	A	0.0000
439	R	A	0.0000
440	D	A	0.0000
441	V	A	0.0000
442	V	A	0.0000
443	S	A	-0.0215
444	I	A	0.0000
445	G	A	-0.1042
446	G	A	-0.2270
447	A	A	-0.2764
448	N	A	-1.3083
449	D	A	-0.6305
450	Q	A	-0.8664
451	V	A	0.0000
452	T	A	0.0000
453	I	A	0.0000
454	R	A	0.0000
455	F	A	0.0000
456	V	A	0.5381
457	T	A	0.0000
458	D	A	-1.7894
459	N	A	0.0000
460	P	A	-0.0263
461	G	A	0.0000
462	P	A	0.0000
463	W	A	0.0000
464	F	A	0.0000
465	L	A	0.0000
466	H	A	0.0000
467	C	A	0.0000
468	H	A	0.0000
469	I	A	0.0000
470	D	A	0.0000
471	W	A	0.1138
472	H	A	-0.0537
473	L	A	-0.1724
474	E	A	-1.7864
475	A	A	-0.3358
476	G	A	0.0000
477	F	A	0.0000
478	A	A	0.0000
479	V	A	0.0000
480	V	A	0.0000
481	F	A	0.0000
482	A	A	0.0000
483	E	A	0.0000
484	G	A	0.0000
485	I	A	0.0000
486	N	A	-1.2860
487	G	A	-0.3006
488	T	A	0.0000
489	A	A	0.0484
490	A	A	0.0682
491	A	A	0.0107
492	N	A	0.0000
493	P	A	-0.1685
494	V	A	0.4060
495	P	A	0.0028
496	A	A	-0.0796
497	A	A	0.0440
498	W	A	0.0000
499	N	A	-1.4801
500	Q	A	-1.3997
501	L	A	0.0000
502	C	A	0.0653
503	P	A	-0.1594
504	L	A	0.4531
505	Y	A	0.0498
506	D	A	-1.7269
507	A	A	-0.1779
508	L	A	0.4652
509	S	A	-0.1164
510	P	A	-0.3313
511	G	A	-0.6411
512	D	A	-1.8384