Project name: 5ivz:B
Status: done
submitted: 2019-03-20 15:59:10, status changed: 2019-03-20 17:28:56
Settings
|
Chain sequence(s)
|
B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8158
-
Maximal score value
-
2.6186
-
Average score
-
-0.4933
-
Total score value
-
-106.5527
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
B |
-1.4371 |
|
| 2 |
V |
B |
-0.7863 |
|
| 3 |
Q |
B |
-1.4124 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
K |
B |
-1.9694 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.8365 |
|
| 8 |
G |
B |
-1.1563 |
|
| 9 |
P |
B |
-0.4759 |
|
| 10 |
G |
B |
-0.3996 |
|
| 11 |
L |
B |
-0.0957 |
|
| 12 |
V |
B |
0.0000 |
|
| 13 |
Q |
B |
-1.6900 |
|
| 14 |
P |
B |
-1.4995 |
|
| 15 |
S |
B |
-1.5844 |
|
| 16 |
Q |
B |
-1.9723 |
|
| 17 |
S |
B |
-1.5974 |
|
| 18 |
L |
B |
0.0000 |
|
| 19 |
S |
B |
-0.6213 |
|
| 20 |
I |
B |
0.0000 |
|
| 21 |
T |
B |
-0.5323 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
T |
B |
-1.0755 |
|
| 24 |
V |
B |
0.0000 |
|
| 25 |
S |
B |
-1.1816 |
|
| 26 |
G |
B |
-0.9699 |
|
| 27 |
F |
B |
-0.5283 |
|
| 28 |
S |
B |
-0.9765 |
|
| 29 |
L |
B |
0.0000 |
|
| 30 |
T |
B |
-1.0271 |
|
| 31 |
N |
B |
-0.9265 |
|
| 32 |
Y |
B |
0.3890 |
|
| 33 |
G |
B |
0.0000 |
|
| 34 |
V |
B |
0.0000 |
|
| 35 |
H |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.2988 |
|
| 40 |
S |
B |
-0.9137 |
|
| 41 |
P |
B |
-1.1150 |
|
| 42 |
G |
B |
-1.6408 |
|
| 43 |
K |
B |
-2.0122 |
|
| 44 |
G |
B |
-0.6201 |
|
| 45 |
L |
B |
0.7972 |
|
| 46 |
E |
B |
0.0000 |
|
| 47 |
W |
B |
0.4521 |
|
| 48 |
L |
B |
0.0000 |
|
| 49 |
G |
B |
0.0000 |
|
| 50 |
V |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
W |
B |
-0.6048 |
|
| 53 |
S |
B |
-0.7476 |
|
| 54 |
G |
B |
-1.3001 |
|
| 55 |
G |
B |
-1.6112 |
|
| 56 |
N |
B |
-1.9439 |
|
| 57 |
T |
B |
-1.4655 |
|
| 58 |
D |
B |
-1.4170 |
|
| 59 |
Y |
B |
-0.6521 |
|
| 60 |
N |
B |
-0.6205 |
|
| 61 |
T |
B |
-0.5247 |
|
| 62 |
P |
B |
-0.4710 |
|
| 63 |
F |
B |
0.0000 |
|
| 64 |
T |
B |
-0.5904 |
|
| 65 |
S |
B |
-0.5384 |
|
| 66 |
R |
B |
-0.9350 |
|
| 67 |
L |
B |
0.0000 |
|
| 68 |
S |
B |
-1.0293 |
|
| 69 |
I |
B |
0.0000 |
|
| 70 |
N |
B |
-1.8076 |
|
| 71 |
K |
B |
-1.5791 |
|
| 72 |
D |
B |
-1.9630 |
|
| 73 |
N |
B |
-2.6191 |
|
| 74 |
S |
B |
-1.8707 |
|
| 75 |
K |
B |
-2.4958 |
|
| 76 |
S |
B |
-1.7848 |
|
| 77 |
Q |
B |
-1.6400 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
F |
B |
-0.3615 |
|
| 80 |
F |
B |
0.0000 |
|
| 81 |
K |
B |
-1.4237 |
|
| 82 |
M |
B |
0.0000 |
|
| 83 |
N |
B |
-1.5617 |
|
| 84 |
S |
B |
-1.4871 |
|
| 85 |
L |
B |
0.0000 |
|
| 86 |
Q |
B |
-2.1817 |
|
| 87 |
S |
B |
-1.5849 |
|
| 88 |
N |
B |
-2.0805 |
|
| 89 |
D |
B |
0.0000 |
|
| 90 |
T |
B |
-0.6951 |
|
| 91 |
A |
B |
0.0000 |
|
| 92 |
I |
B |
0.4986 |
|
| 93 |
Y |
B |
0.0000 |
|
| 94 |
Y |
B |
-0.0714 |
|
| 95 |
C |
B |
0.0000 |
|
| 96 |
A |
B |
0.0000 |
|
| 97 |
R |
B |
0.0000 |
|
| 98 |
A |
B |
0.0000 |
|
| 99 |
L |
B |
1.6478 |
|
| 100 |
T |
B |
1.3444 |
|
| 101 |
Y |
B |
1.9355 |
|
| 102 |
Y |
B |
1.8017 |
|
| 103 |
D |
B |
0.9003 |
|
| 104 |
Y |
B |
0.9082 |
|
| 105 |
E |
B |
0.1044 |
|
| 106 |
F |
B |
0.6705 |
|
| 107 |
A |
B |
0.7697 |
|
| 108 |
Y |
B |
0.5569 |
|
| 109 |
W |
B |
0.1492 |
|
| 110 |
G |
B |
0.0000 |
|
| 111 |
Q |
B |
-1.4336 |
|
| 112 |
G |
B |
-0.6349 |
|
| 113 |
T |
B |
0.0000 |
|
| 114 |
L |
B |
0.2138 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
T |
B |
0.0000 |
|
| 117 |
V |
B |
0.0000 |
|
| 118 |
S |
B |
-0.6151 |
|
| 119 |
A |
B |
-0.3766 |
|
| 120 |
A |
B |
-0.3085 |
|
| 121 |
S |
B |
-0.5283 |
|
| 122 |
T |
B |
-0.8947 |
|
| 123 |
K |
B |
-1.2603 |
|
| 124 |
G |
B |
-1.4425 |
|
| 125 |
P |
B |
0.0000 |
|
| 126 |
S |
B |
-0.0319 |
|
| 127 |
V |
B |
0.0000 |
|
| 128 |
F |
B |
1.0714 |
|
| 129 |
P |
B |
-0.0796 |
|
| 130 |
L |
B |
0.3500 |
|
| 131 |
A |
B |
-0.9327 |
|
| 132 |
P |
B |
0.0000 |
|
| 133 |
S |
B |
-0.7985 |
|
| 138 |
S |
B |
-0.6566 |
|
| 139 |
G |
B |
-0.8513 |
|
| 140 |
G |
B |
-0.9257 |
|
| 141 |
T |
B |
-0.6398 |
|
| 142 |
A |
B |
-0.3750 |
|
| 143 |
A |
B |
0.0949 |
|
| 144 |
L |
B |
0.0000 |
|
| 145 |
G |
B |
0.0000 |
|
| 146 |
C |
B |
0.0000 |
|
| 147 |
L |
B |
0.7808 |
|
| 148 |
V |
B |
0.0000 |
|
| 149 |
K |
B |
-0.1821 |
|
| 150 |
D |
B |
-0.6613 |
|
| 151 |
Y |
B |
0.0000 |
|
| 152 |
F |
B |
0.0000 |
|
| 153 |
P |
B |
0.0000 |
|
| 154 |
E |
B |
-0.3653 |
|
| 155 |
P |
B |
-0.5837 |
|
| 156 |
V |
B |
-0.5932 |
|
| 157 |
T |
B |
-0.5598 |
|
| 158 |
V |
B |
-0.1496 |
|
| 159 |
S |
B |
-0.5003 |
|
| 160 |
W |
B |
0.0000 |
|
| 161 |
N |
B |
-0.9391 |
|
| 162 |
S |
B |
-0.7061 |
|
| 163 |
G |
B |
-0.5700 |
|
| 164 |
A |
B |
-0.2345 |
|
| 165 |
L |
B |
-0.0073 |
|
| 166 |
T |
B |
-0.2596 |
|
| 167 |
S |
B |
-0.2786 |
|
| 168 |
G |
B |
-0.2803 |
|
| 169 |
V |
B |
0.0939 |
|
| 170 |
H |
B |
-0.3550 |
|
| 171 |
T |
B |
0.4821 |
|
| 172 |
F |
B |
1.7027 |
|
| 173 |
P |
B |
1.1143 |
|
| 174 |
A |
B |
1.5140 |
|
| 175 |
V |
B |
2.6186 |
|
| 176 |
L |
B |
2.0953 |
|
| 177 |
Q |
B |
0.6154 |
|
| 178 |
S |
B |
0.0548 |
|
| 179 |
S |
B |
-0.2570 |
|
| 180 |
G |
B |
0.1421 |
|
| 181 |
L |
B |
0.2054 |
|
| 182 |
Y |
B |
0.0000 |
|
| 183 |
S |
B |
0.0000 |
|
| 184 |
L |
B |
1.1693 |
|
| 185 |
S |
B |
0.9507 |
|
| 186 |
S |
B |
0.0000 |
|
| 187 |
V |
B |
0.5206 |
|
| 188 |
V |
B |
0.0000 |
|
| 189 |
T |
B |
-0.1425 |
|
| 190 |
V |
B |
0.0000 |
|
| 191 |
P |
B |
-0.5508 |
|
| 192 |
S |
B |
-0.5778 |
|
| 193 |
S |
B |
-0.5869 |
|
| 194 |
S |
B |
-0.6014 |
|
| 195 |
L |
B |
-0.7173 |
|
| 196 |
G |
B |
-0.9071 |
|
| 197 |
T |
B |
-0.6897 |
|
| 198 |
Q |
B |
-1.0072 |
|
| 199 |
T |
B |
-1.1504 |
|
| 200 |
Y |
B |
0.0000 |
|
| 201 |
I |
B |
-1.5769 |
|
| 202 |
C |
B |
0.0000 |
|
| 203 |
N |
B |
-1.6050 |
|
| 204 |
V |
B |
0.0000 |
|
| 205 |
N |
B |
-2.0390 |
|
| 206 |
H |
B |
0.0000 |
|
| 207 |
K |
B |
-2.7481 |
|
| 208 |
P |
B |
-1.5668 |
|
| 209 |
S |
B |
-1.8267 |
|
| 210 |
N |
B |
-2.5672 |
|
| 211 |
T |
B |
-2.0432 |
|
| 212 |
K |
B |
-2.7436 |
|
| 213 |
V |
B |
-1.7643 |
|
| 214 |
D |
B |
-2.6764 |
|
| 215 |
K |
B |
-2.2001 |
|
| 216 |
R |
B |
-2.7105 |
|
| 217 |
V |
B |
0.0000 |
|
| 218 |
E |
B |
-2.8158 |
|
| 219 |
P |
B |
-1.8913 |
|
| 220 |
K |
B |
-2.2823 |
|