Project name: 4edw:H

Chain sequence(s)	H: QVQLQESGPGLVKPSETLSLTCTVSGFSLIGYDLNWIRQPPGKGLEWIGIIWGDGTTDYNSAVKSRVTISKDTSKNQFSLKLSSVTAADTAVYYCARGGYWYATSYYFDYWGQGTLVTVSSASTKGPSVFPLAPCSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTYTCNVDHKPSNTKVDKTVER
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8926
• Maximal score value: 2.5302
• Average score: -0.4138
• Total score value: -88.9662

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.4672
2	V	H	-0.7294
3	Q	H	-1.6136
4	L	H	0.0000
5	Q	H	-1.7160
6	E	H	0.0000
7	S	H	-0.6459
8	G	H	-0.6621
9	P	H	-0.6067
10	G	H	-0.4488
11	L	H	-0.3897
12	V	H	0.0000
13	K	H	-2.4226
14	P	H	-1.6789
15	S	H	-1.6885
16	E	H	-2.5840
17	T	H	-1.6451
18	L	H	0.0000
19	S	H	-0.8289
20	L	H	0.0000
21	T	H	-0.7032
22	C	H	0.0000
23	T	H	-1.3811
24	V	H	0.0000
25	S	H	-1.2135
26	G	H	-1.0756
27	F	H	-0.2095
28	S	H	0.2853
29	L	H	0.0000
30	I	H	1.3263
31	G	H	0.4345
32	Y	H	0.7794
33	D	H	0.0000
34	L	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	I	H	0.0000
38	R	H	0.0000
39	Q	H	-0.5222
40	P	H	-0.8248
41	P	H	-1.1159
42	G	H	-1.5852
43	K	H	-2.0872
44	G	H	-0.9302
45	L	H	0.6294
46	E	H	-0.1140
47	W	H	0.3240
48	I	H	0.0000
49	G	H	0.0000
50	I	H	0.0000
51	I	H	0.0000
52	W	H	-0.2149
53	G	H	-0.1308
54	D	H	-1.3949
55	G	H	-0.8297
56	T	H	-1.0308
57	T	H	-1.1034
58	D	H	-1.9972
59	Y	H	-1.4443
60	N	H	-1.2475
61	S	H	-1.2106
62	A	H	-0.6662
63	V	H	0.0000
64	K	H	-2.2044
65	S	H	-1.2413
66	R	H	-1.2430
67	V	H	0.0000
68	T	H	-0.9964
69	I	H	0.0000
70	S	H	-0.7155
71	K	H	-1.0308
72	D	H	-1.5713
73	T	H	-1.0685
74	S	H	-1.5519
75	K	H	-2.4838
76	N	H	-2.0240
77	Q	H	-1.7518
78	F	H	0.0000
79	S	H	-0.6631
80	L	H	0.0000
81	K	H	-1.1763
82	L	H	0.0000
82A	S	H	-1.1710
82B	S	H	-1.2684
82C	V	H	0.0000
83	T	H	-0.6839
84	A	H	-0.1951
85	A	H	0.0595
86	D	H	0.0000
87	T	H	0.0237
88	A	H	0.0000
89	V	H	0.2607
90	Y	H	0.0000
91	Y	H	0.0099
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	G	H	0.0000
96	G	H	0.0000
97	Y	H	2.4190
98	W	H	2.5193
99	Y	H	2.2478
100	A	H	1.2749
100A	T	H	0.9915
100B	S	H	1.3672
100C	Y	H	1.7914
100D	Y	H	1.6807
100E	F	H	1.2744
101	D	H	0.5566
102	Y	H	0.6968
103	W	H	0.2430
104	G	H	0.0000
105	Q	H	-1.3593
106	G	H	-0.6931
107	T	H	-0.3903
108	L	H	0.0536
109	V	H	0.0000
110	T	H	-0.2586
111	V	H	0.0000
112	S	H	-0.6931
113	S	H	-0.8603
114	A	H	-0.5414
115	S	H	-0.6395
116	T	H	-0.6973
117	K	H	-1.1713
118	G	H	-1.4972
119	P	H	-0.6881
120	S	H	-0.1478
121	V	H	0.0000
122	F	H	1.1558
123	P	H	0.3594
124	L	H	0.4531
125	A	H	-0.4281
126	P	H	-0.4246
127	C	H	0.3318
128	S	H	-0.1922
135	T	H	-0.3473
136	A	H	-0.4987
137	A	H	-0.1367
138	L	H	0.0000
139	G	H	0.0000
140	C	H	0.0000
141	L	H	0.6120
142	V	H	0.0000
143	K	H	-0.2888
144	D	H	-0.7773
145	Y	H	0.0000
146	F	H	-0.2649
147	P	H	0.0000
148	E	H	-0.4162
149	P	H	-0.6959
150	V	H	0.0000
151	T	H	-0.7030
152	V	H	-0.2400
153	S	H	-0.5418
154	W	H	0.0000
155	N	H	-0.8734
156	S	H	-0.8267
157	G	H	-0.6175
158	A	H	-0.2836
159	L	H	-0.0782
160	T	H	-0.2812
161	S	H	-0.2635
162	G	H	-0.2471
163	V	H	-0.0137
164	H	H	-0.5277
165	T	H	0.1552
166	F	H	0.9864
167	P	H	0.7533
168	A	H	1.2904
169	V	H	2.5302
170	L	H	2.1516
171	Q	H	0.6830
172	S	H	0.0758
173	S	H	-0.2411
174	G	H	0.2295
175	L	H	0.3128
176	Y	H	0.7820
177	S	H	0.0000
178	L	H	0.0000
179	S	H	0.6234
180	S	H	0.0000
181	V	H	0.3272
182	V	H	0.0000
183	T	H	-0.1949
184	V	H	0.0000
185	P	H	-0.5741
186	S	H	-0.5505
187	S	H	-0.6414
188	N	H	-0.9579
189	F	H	-1.1320
190	G	H	-0.7772
191	T	H	-0.7397
192	Q	H	-1.3487
193	T	H	-1.1735
194	Y	H	0.0000
195	T	H	-1.1875
196	C	H	0.0000
197	N	H	-1.5152
198	V	H	0.0000
199	D	H	-2.2402
200	H	H	0.0000
201	K	H	-2.8926
202	P	H	-1.6716
203	S	H	-1.8075
204	N	H	-2.6528
205	T	H	-2.1476
206	K	H	-2.8502
207	V	H	-1.5950
208	D	H	-2.3912
209	K	H	-1.4639
210	T	H	-1.0537
211	V	H	0.0000
212	E	H	-2.8355
213	R	H	-2.5865