Project name: 5l6y:H

Chain sequence(s)	H: VQLVQSGAEVKKPGASVKVSCKASGYTFTNYGLSWVRQAPGQGLEWMGWISANNGDTNYGQEFQGRVTMTTDTSTSTAYMELRSLRSDDTAVYYCCARDSSSSWARWFFDLWGRGTLVTVSSASTKGPSVFPLAPISKSTSGGTAALGCCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVVTVGPSQTYICNVNHKPSNTKVDKRVESKYGPPSPSSPAPAKN
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0686
• Maximal score value: 2.0366
• Average score: -0.5272
• Total score value: -122.3011

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	1.0323
3	Q	H	-0.4233
4	L	H	0.0000
5	V	H	0.0594
6	Q	H	-0.4260
7	S	H	-0.6724
8	G	H	-0.4590
9	A	H	0.0023
10	E	H	-0.3803
11	V	H	0.4242
12	K	H	-1.1165
13	K	H	-2.2084
14	P	H	-2.2454
15	G	H	-1.6669
16	A	H	-1.3431
17	S	H	-1.5370
18	V	H	0.0000
19	K	H	-2.0612
20	V	H	0.0000
21	S	H	-0.5124
22	C	H	0.0000
23	K	H	-0.7759
24	A	H	0.0000
25	S	H	-0.1625
26	G	H	0.0402
27	Y	H	0.0510
28	T	H	-0.2258
29	F	H	0.0000
30	T	H	-1.3711
31	N	H	-1.5826
32	Y	H	-0.5698
33	G	H	0.0000
34	L	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.0536
39	Q	H	-0.4069
40	A	H	-0.9231
41	P	H	-0.8778
42	G	H	-1.1683
43	Q	H	-1.6101
44	G	H	-0.7506
45	L	H	0.6193
46	E	H	-0.4479
47	W	H	0.0219
48	M	H	0.0000
49	G	H	0.0000
50	W	H	0.0000
51	I	H	0.0000
52	S	H	0.0000
52A	A	H	0.0000
53	N	H	-2.4320
54	N	H	-2.4962
55	G	H	-1.8510
56	D	H	-2.1226
57	T	H	-1.3738
58	N	H	-1.7362
59	Y	H	-1.3838
60	G	H	0.0000
61	Q	H	-2.5658
62	E	H	-2.8565
63	F	H	0.0000
64	Q	H	-2.5534
65	G	H	-1.7008
66	R	H	-1.5768
67	V	H	0.0000
68	T	H	-0.8988
69	M	H	0.0000
70	T	H	-0.3915
71	T	H	-0.9289
72	D	H	-0.8667
73	T	H	-0.8830
74	S	H	-0.4837
75	T	H	-0.5589
76	S	H	-0.6130
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.5011
80	M	H	0.0000
81	E	H	-1.4426
82	L	H	0.0000
82A	R	H	-1.5824
82B	S	H	-1.4117
82C	L	H	0.0000
83	R	H	-3.0686
84	S	H	-2.3569
85	D	H	-2.5043
86	D	H	0.0000
87	T	H	-0.7966
88	A	H	0.0000
89	V	H	0.4537
90	Y	H	0.0000
91	Y	H	0.1088
92	C	H	0.0000
93	A	H	0.0000
94	R	H	-0.0055
95	D	H	0.0000
96	S	H	0.0000
97	S	H	-0.7374
98	S	H	-0.1160
99	S	H	-0.2016
100	W	H	1.0499
100A	A	H	0.5010
100B	R	H	0.6097
100C	W	H	1.7550
100D	F	H	2.0366
100E	F	H	0.6458
101	D	H	-0.8349
102	L	H	-0.3701
103	W	H	-0.3534
104	G	H	0.0000
105	R	H	-1.5177
106	G	H	-0.5537
107	T	H	0.0000
108	L	H	0.5387
109	V	H	0.0000
110	T	H	0.0000
111	V	H	0.0000
112	S	H	0.0000
113	S	H	-1.1263
123	A	H	-0.5782
124	S	H	-0.6719
125	T	H	-0.6688
126	K	H	-1.0825
127	G	H	-1.3559
128	P	H	-0.4982
129	S	H	-0.0518
130	V	H	0.0000
131	F	H	0.9135
132	P	H	0.0156
133	L	H	0.5303
134	A	H	-0.0508
135	P	H	0.0816
136	I	H	0.7270
137	S	H	-0.4198
138	K	H	-0.7380
139	S	H	-0.5534
140	T	H	-0.6269
141	S	H	-0.7466
142	G	H	-0.7616
143	G	H	-0.5886
144	T	H	-0.4308
145	A	H	-0.3333
146	A	H	0.1054
147	L	H	0.0000
148	G	H	0.0000
149	C	H	0.0000
150	L	H	0.6967
151	V	H	0.0000
152	K	H	-0.1122
153	D	H	-0.4642
154	Y	H	0.0000
155	F	H	0.0000
156	P	H	-0.7105
157	E	H	-1.1539
158	P	H	-1.0529
159	V	H	-0.5560
160	T	H	-0.5080
161	V	H	0.0610
162	S	H	-0.3327
163	W	H	0.0000
164	N	H	-0.7258
165	S	H	-0.5511
166	G	H	-0.3322
167	A	H	-0.1704
168	L	H	0.0392
169	T	H	-0.2651
170	S	H	-0.3265
171	G	H	-0.3824
172	V	H	0.0102
173	H	H	-0.5201
174	T	H	0.2002
175	F	H	1.0868
176	P	H	0.6514
177	A	H	0.9631
178	V	H	1.9735
179	L	H	1.0287
180	Q	H	0.2360
181	S	H	-0.3701
182	S	H	-0.3795
183	G	H	0.0000
184	L	H	-0.0069
185	Y	H	0.3312
186	S	H	0.0000
187	L	H	0.0000
188	S	H	0.6664
189	S	H	0.0000
190	V	H	0.4087
191	V	H	0.0000
192	T	H	-0.1589
193	V	H	-0.1233
194	G	H	-0.6382
195	P	H	-0.6622
196	S	H	-0.8916
201	Q	H	-1.4149
202	T	H	-1.2196
203	Y	H	-1.0258
204	I	H	-1.3136
205	C	H	0.0000
206	N	H	0.0000
207	V	H	0.0000
208	N	H	-1.5901
209	H	H	0.0000
210	K	H	-2.7741
211	P	H	-1.7134
212	S	H	-1.8031
213	N	H	-2.5611
214	T	H	-2.0059
215	K	H	-2.5682
216	V	H	-1.5873
217	D	H	-2.5742
218	K	H	-1.9995
219	R	H	-2.5855
220	V	H	0.0000
221	E	H	-2.6179
222	S	H	-1.4240
223	K	H	-1.6524
224	Y	H	-0.7082
225	G	H	-0.9218
226	P	H	-0.7321
227	P	H	-0.5540
228	S	H	-0.4721
229	P	H	-0.5725
230	S	H	-0.4619
231	S	H	-0.3728
232	P	H	-0.3733
233	A	H	-0.5318
234	P	H	-0.6554
235	A	H	-1.0898
236	K	H	-2.1221
237	N	H	-1.6951