Project name: 5wux:C
Status: done
submitted: 2019-03-20 16:14:55, status changed: 2019-03-20 17:32:11
Settings
|
Chain sequence(s)
|
C: EVQLVESGGGLVQPGGSLRLSCAASGYVFTDYGMNWVRQAPGKGLEWMGWINTYIGEPIYADSVKGRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCARGYRSYAMDYWGQGTLVTVSSASTKGPSVFPLAPALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSTYICNVNHKPSNTKVDKKV
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8229
-
Maximal score value
-
2.5294
-
Average score
-
-0.4644
-
Total score value
-
-93.81
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
C |
-2.1122 |
|
| 2 |
V |
C |
-1.0120 |
|
| 3 |
Q |
C |
-1.3689 |
|
| 4 |
L |
C |
0.0000 |
|
| 5 |
V |
C |
0.2310 |
|
| 6 |
E |
C |
0.0000 |
|
| 7 |
S |
C |
-0.6133 |
|
| 8 |
G |
C |
-0.9806 |
|
| 9 |
G |
C |
-0.7937 |
|
| 10 |
G |
C |
-0.4711 |
|
| 11 |
L |
C |
-0.1160 |
|
| 12 |
V |
C |
0.0000 |
|
| 13 |
Q |
C |
-1.4891 |
|
| 14 |
P |
C |
-1.8620 |
|
| 15 |
G |
C |
-1.6254 |
|
| 16 |
G |
C |
-1.3218 |
|
| 17 |
S |
C |
-1.4625 |
|
| 18 |
L |
C |
-1.3494 |
|
| 19 |
R |
C |
-2.2368 |
|
| 20 |
L |
C |
0.0000 |
|
| 21 |
S |
C |
-0.4717 |
|
| 22 |
C |
C |
0.0000 |
|
| 23 |
A |
C |
-0.3024 |
|
| 24 |
A |
C |
-0.2226 |
|
| 25 |
S |
C |
-0.6048 |
|
| 26 |
G |
C |
-0.7322 |
|
| 27 |
Y |
C |
0.1271 |
|
| 28 |
V |
C |
1.2118 |
|
| 29 |
F |
C |
0.0000 |
|
| 30 |
T |
C |
0.3495 |
|
| 31 |
D |
C |
-0.7272 |
|
| 32 |
Y |
C |
-0.0523 |
|
| 33 |
G |
C |
0.0000 |
|
| 34 |
M |
C |
0.0000 |
|
| 35 |
N |
C |
0.0000 |
|
| 36 |
W |
C |
0.0000 |
|
| 37 |
V |
C |
0.0000 |
|
| 38 |
R |
C |
-0.1502 |
|
| 39 |
Q |
C |
-0.5573 |
|
| 40 |
A |
C |
-1.2274 |
|
| 41 |
P |
C |
-1.2998 |
|
| 42 |
G |
C |
-1.3839 |
|
| 43 |
K |
C |
-2.0847 |
|
| 44 |
G |
C |
-0.9497 |
|
| 45 |
L |
C |
0.5340 |
|
| 46 |
E |
C |
-0.2889 |
|
| 47 |
W |
C |
0.4958 |
|
| 48 |
M |
C |
0.0000 |
|
| 49 |
G |
C |
0.0000 |
|
| 50 |
W |
C |
0.0000 |
|
| 51 |
I |
C |
0.0000 |
|
| 52 |
N |
C |
-0.3141 |
|
| 53 |
T |
C |
0.0000 |
|
| 54 |
Y |
C |
1.5152 |
|
| 55 |
I |
C |
1.8383 |
|
| 56 |
G |
C |
0.1700 |
|
| 57 |
E |
C |
-1.1047 |
|
| 58 |
P |
C |
-0.4952 |
|
| 59 |
I |
C |
0.0100 |
|
| 60 |
Y |
C |
-0.2900 |
|
| 61 |
A |
C |
-1.0880 |
|
| 62 |
D |
C |
-2.4431 |
|
| 63 |
S |
C |
-1.8581 |
|
| 64 |
V |
C |
0.0000 |
|
| 65 |
K |
C |
-2.7701 |
|
| 66 |
G |
C |
-2.0410 |
|
| 67 |
R |
C |
-2.0544 |
|
| 68 |
F |
C |
0.0000 |
|
| 69 |
T |
C |
-0.9929 |
|
| 70 |
F |
C |
0.0000 |
|
| 71 |
S |
C |
-0.6068 |
|
| 72 |
L |
C |
-0.3638 |
|
| 73 |
D |
C |
-1.0206 |
|
| 74 |
T |
C |
-0.7607 |
|
| 75 |
S |
C |
-1.1975 |
|
| 76 |
K |
C |
-1.9641 |
|
| 77 |
S |
C |
-0.7844 |
|
| 78 |
T |
C |
0.0000 |
|
| 79 |
A |
C |
0.0000 |
|
| 80 |
Y |
C |
-0.4567 |
|
| 81 |
L |
C |
0.0000 |
|
| 82 |
Q |
C |
-1.5704 |
|
| 83 |
M |
C |
0.0000 |
|
| 84 |
N |
C |
-2.3330 |
|
| 85 |
S |
C |
-1.7336 |
|
| 86 |
L |
C |
0.0000 |
|
| 87 |
R |
C |
-2.8229 |
|
| 88 |
A |
C |
-1.9674 |
|
| 89 |
E |
C |
-2.4736 |
|
| 90 |
D |
C |
-1.6368 |
|
| 91 |
T |
C |
-0.9765 |
|
| 92 |
A |
C |
0.0000 |
|
| 93 |
V |
C |
0.0254 |
|
| 94 |
Y |
C |
0.0000 |
|
| 95 |
Y |
C |
0.3924 |
|
| 96 |
C |
C |
0.0000 |
|
| 97 |
A |
C |
0.0000 |
|
| 98 |
R |
C |
0.0000 |
|
| 99 |
G |
C |
0.0000 |
|
| 100 |
Y |
C |
0.1317 |
|
| 101 |
R |
C |
-0.9880 |
|
| 102 |
S |
C |
-0.1553 |
|
| 103 |
Y |
C |
0.8714 |
|
| 104 |
A |
C |
0.3569 |
|
| 105 |
M |
C |
0.0141 |
|
| 106 |
D |
C |
-0.8975 |
|
| 107 |
Y |
C |
-0.2900 |
|
| 108 |
W |
C |
0.0552 |
|
| 109 |
G |
C |
0.0000 |
|
| 110 |
Q |
C |
-0.9567 |
|
| 111 |
G |
C |
-0.3338 |
|
| 112 |
T |
C |
-0.2281 |
|
| 113 |
L |
C |
0.0287 |
|
| 114 |
V |
C |
0.0000 |
|
| 115 |
T |
C |
-0.6002 |
|
| 116 |
V |
C |
0.0000 |
|
| 117 |
S |
C |
-1.0161 |
|
| 118 |
S |
C |
-0.6048 |
|
| 119 |
A |
C |
-0.4719 |
|
| 120 |
S |
C |
-0.6667 |
|
| 121 |
T |
C |
-0.9969 |
|
| 122 |
K |
C |
-1.7111 |
|
| 123 |
G |
C |
-1.6376 |
|
| 124 |
P |
C |
-0.7506 |
|
| 125 |
S |
C |
-0.3160 |
|
| 126 |
V |
C |
0.0000 |
|
| 127 |
F |
C |
0.6831 |
|
| 128 |
P |
C |
0.5544 |
|
| 129 |
L |
C |
0.7932 |
|
| 130 |
A |
C |
0.5440 |
|
| 131 |
P |
C |
-0.0320 |
|
| 142 |
A |
C |
0.1492 |
|
| 143 |
L |
C |
0.0000 |
|
| 144 |
G |
C |
0.0000 |
|
| 145 |
C |
C |
0.0000 |
|
| 146 |
L |
C |
0.7048 |
|
| 147 |
V |
C |
0.0000 |
|
| 148 |
K |
C |
-0.2791 |
|
| 149 |
D |
C |
-0.7022 |
|
| 150 |
Y |
C |
0.0000 |
|
| 151 |
F |
C |
-0.4555 |
|
| 152 |
P |
C |
0.0000 |
|
| 153 |
E |
C |
-0.6092 |
|
| 154 |
P |
C |
-0.7793 |
|
| 155 |
V |
C |
-0.4866 |
|
| 156 |
T |
C |
-0.4568 |
|
| 157 |
V |
C |
-0.1319 |
|
| 158 |
S |
C |
-0.4827 |
|
| 159 |
W |
C |
0.0000 |
|
| 160 |
N |
C |
-0.7588 |
|
| 161 |
S |
C |
-0.6803 |
|
| 162 |
G |
C |
-0.5113 |
|
| 163 |
A |
C |
-0.1388 |
|
| 164 |
L |
C |
0.1379 |
|
| 165 |
T |
C |
-0.2370 |
|
| 166 |
S |
C |
-0.3443 |
|
| 167 |
G |
C |
-0.4411 |
|
| 168 |
V |
C |
0.0029 |
|
| 169 |
H |
C |
-0.5390 |
|
| 170 |
T |
C |
0.1799 |
|
| 171 |
F |
C |
1.0419 |
|
| 172 |
P |
C |
0.7665 |
|
| 173 |
A |
C |
1.2640 |
|
| 174 |
V |
C |
2.5294 |
|
| 175 |
L |
C |
2.1587 |
|
| 176 |
Q |
C |
0.7005 |
|
| 177 |
S |
C |
0.1150 |
|
| 178 |
S |
C |
-0.2349 |
|
| 179 |
G |
C |
0.2188 |
|
| 180 |
L |
C |
0.2729 |
|
| 181 |
Y |
C |
0.8203 |
|
| 182 |
S |
C |
0.0000 |
|
| 183 |
L |
C |
0.0000 |
|
| 184 |
S |
C |
0.6289 |
|
| 185 |
S |
C |
0.0000 |
|
| 186 |
V |
C |
0.4993 |
|
| 187 |
V |
C |
0.0000 |
|
| 188 |
T |
C |
-0.1141 |
|
| 189 |
V |
C |
0.0401 |
|
| 190 |
P |
C |
-0.3604 |
|
| 191 |
S |
C |
-0.4543 |
|
| 192 |
S |
C |
-0.4606 |
|
| 193 |
S |
C |
-0.3667 |
|
| 198 |
T |
C |
-0.0413 |
|
| 199 |
Y |
C |
-0.1443 |
|
| 200 |
I |
C |
-0.7366 |
|
| 201 |
C |
C |
0.0000 |
|
| 202 |
N |
C |
-1.7064 |
|
| 203 |
V |
C |
0.0000 |
|
| 204 |
N |
C |
-1.8620 |
|
| 205 |
H |
C |
0.0000 |
|
| 206 |
K |
C |
-2.7193 |
|
| 207 |
P |
C |
-1.6694 |
|
| 208 |
S |
C |
-1.8691 |
|
| 209 |
N |
C |
-2.5105 |
|
| 210 |
T |
C |
-2.2375 |
|
| 211 |
K |
C |
-2.7274 |
|
| 212 |
V |
C |
-1.9917 |
|
| 213 |
D |
C |
-2.7130 |
|
| 214 |
K |
C |
-1.8782 |
|
| 215 |
K |
C |
-1.6532 |
|
| 216 |
V |
C |
0.1542 |
|