Project name: 5x8m:c
Status: done
submitted: 2019-03-20 20:40:02, status changed: 2019-03-20 20:48:07
Settings
|
Chain sequence(s)
|
C: IVLTQSPGTLSLSPGERATLSCRASQRVSSSYLAWYQQKPGQAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSLPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8419
-
Maximal score value
-
2.2343
-
Average score
-
-0.8153
-
Total score value
-
-173.6542
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
I |
C |
1.1869 |
|
| 3 |
V |
C |
1.6538 |
|
| 4 |
L |
C |
0.0000 |
|
| 5 |
T |
C |
-0.5664 |
|
| 6 |
Q |
C |
0.0000 |
|
| 7 |
S |
C |
-0.8873 |
|
| 8 |
P |
C |
-0.5240 |
|
| 9 |
G |
C |
-0.8242 |
|
| 10 |
T |
C |
-0.4071 |
|
| 11 |
L |
C |
-0.1791 |
|
| 12 |
S |
C |
-0.4457 |
|
| 13 |
L |
C |
-0.9030 |
|
| 14 |
S |
C |
-1.4783 |
|
| 15 |
P |
C |
-1.9917 |
|
| 16 |
G |
C |
-2.2828 |
|
| 17 |
E |
C |
-2.7945 |
|
| 18 |
R |
C |
-3.2021 |
|
| 19 |
A |
C |
0.0000 |
|
| 20 |
T |
C |
-0.5455 |
|
| 21 |
L |
C |
0.0000 |
|
| 22 |
S |
C |
-0.9903 |
|
| 23 |
C |
C |
0.0000 |
|
| 24 |
R |
C |
-2.7536 |
|
| 25 |
A |
C |
0.0000 |
|
| 26 |
S |
C |
-1.0742 |
|
| 27 |
Q |
C |
-2.2262 |
|
| 28 |
R |
C |
-3.0205 |
|
| 29 |
V |
C |
0.0000 |
|
| 30 |
S |
C |
-0.8805 |
|
| 31 |
S |
C |
-0.5886 |
|
| 32 |
S |
C |
-0.7579 |
|
| 33 |
Y |
C |
0.2221 |
|
| 34 |
L |
C |
0.0000 |
|
| 35 |
A |
C |
0.0000 |
|
| 36 |
W |
C |
0.0000 |
|
| 37 |
Y |
C |
0.2171 |
|
| 38 |
Q |
C |
0.0000 |
|
| 39 |
Q |
C |
-0.9705 |
|
| 40 |
K |
C |
-1.5252 |
|
| 41 |
P |
C |
-1.2988 |
|
| 42 |
G |
C |
-1.1442 |
|
| 43 |
Q |
C |
-1.5678 |
|
| 44 |
A |
C |
-0.9925 |
|
| 45 |
P |
C |
-1.0720 |
|
| 46 |
R |
C |
-1.4302 |
|
| 47 |
L |
C |
-0.0462 |
|
| 48 |
L |
C |
0.0000 |
|
| 49 |
I |
C |
0.0000 |
|
| 50 |
Y |
C |
0.2291 |
|
| 51 |
D |
C |
-0.6468 |
|
| 52 |
A |
C |
0.0000 |
|
| 53 |
S |
C |
-0.7154 |
|
| 54 |
S |
C |
-0.6810 |
|
| 55 |
R |
C |
-1.2818 |
|
| 56 |
A |
C |
-0.5030 |
|
| 57 |
T |
C |
-0.3525 |
|
| 58 |
G |
C |
-0.7502 |
|
| 59 |
I |
C |
-0.8043 |
|
| 60 |
P |
C |
-1.2264 |
|
| 61 |
D |
C |
-2.2039 |
|
| 62 |
R |
C |
-2.1201 |
|
| 63 |
F |
C |
0.0000 |
|
| 64 |
S |
C |
-0.9610 |
|
| 65 |
G |
C |
-0.6247 |
|
| 66 |
S |
C |
-0.9247 |
|
| 67 |
G |
C |
-1.4718 |
|
| 68 |
S |
C |
-1.3716 |
|
| 69 |
G |
C |
-1.9051 |
|
| 70 |
T |
C |
-2.6355 |
|
| 71 |
D |
C |
-3.1340 |
|
| 72 |
F |
C |
0.0000 |
|
| 73 |
T |
C |
-0.9796 |
|
| 74 |
L |
C |
0.0000 |
|
| 75 |
T |
C |
-0.8113 |
|
| 76 |
I |
C |
0.0000 |
|
| 77 |
S |
C |
-2.6016 |
|
| 78 |
R |
C |
-3.3005 |
|
| 79 |
L |
C |
0.0000 |
|
| 80 |
E |
C |
-2.5371 |
|
| 81 |
P |
C |
-1.5940 |
|
| 82 |
E |
C |
-2.2772 |
|
| 83 |
D |
C |
0.0000 |
|
| 84 |
F |
C |
-0.6455 |
|
| 85 |
A |
C |
0.0000 |
|
| 86 |
V |
C |
-0.1548 |
|
| 87 |
Y |
C |
0.0000 |
|
| 88 |
Y |
C |
0.1975 |
|
| 89 |
C |
C |
0.0000 |
|
| 90 |
Q |
C |
0.0000 |
|
| 91 |
Q |
C |
0.0000 |
|
| 92 |
Y |
C |
1.1754 |
|
| 93 |
G |
C |
0.2988 |
|
| 94 |
S |
C |
0.6797 |
|
| 95 |
L |
C |
1.8732 |
|
| 96 |
P |
C |
1.4998 |
|
| 97 |
W |
C |
2.2343 |
|
| 98 |
T |
C |
1.8699 |
|
| 99 |
F |
C |
1.8766 |
|
| 100 |
G |
C |
0.3002 |
|
| 101 |
Q |
C |
-0.6776 |
|
| 102 |
G |
C |
0.0000 |
|
| 103 |
T |
C |
0.0000 |
|
| 104 |
K |
C |
-0.5153 |
|
| 105 |
V |
C |
0.0000 |
|
| 106 |
E |
C |
0.0000 |
|
| 107 |
I |
C |
-0.8193 |
|
| 108 |
K |
C |
-1.3423 |
|
| 109 |
R |
C |
-0.9741 |
|
| 110 |
T |
C |
-0.1428 |
|
| 111 |
V |
C |
0.2013 |
|
| 112 |
A |
C |
-0.1655 |
|
| 113 |
A |
C |
-0.2403 |
|
| 114 |
P |
C |
0.0000 |
|
| 115 |
S |
C |
-0.1832 |
|
| 116 |
V |
C |
0.0000 |
|
| 117 |
F |
C |
1.0531 |
|
| 118 |
I |
C |
1.0817 |
|
| 119 |
F |
C |
1.4028 |
|
| 120 |
P |
C |
0.0331 |
|
| 121 |
P |
C |
-0.7922 |
|
| 122 |
S |
C |
-1.7844 |
|
| 123 |
D |
C |
-3.1635 |
|
| 124 |
E |
C |
-3.3145 |
|
| 125 |
Q |
C |
-2.4464 |
|
| 126 |
L |
C |
-2.5158 |
|
| 127 |
K |
C |
-2.9034 |
|
| 128 |
S |
C |
-1.8490 |
|
| 129 |
G |
C |
-1.3241 |
|
| 130 |
T |
C |
-0.9626 |
|
| 131 |
A |
C |
0.0000 |
|
| 132 |
S |
C |
0.0432 |
|
| 133 |
V |
C |
0.0000 |
|
| 134 |
V |
C |
0.7010 |
|
| 135 |
C |
C |
0.0000 |
|
| 136 |
L |
C |
0.4874 |
|
| 137 |
L |
C |
0.0000 |
|
| 138 |
N |
C |
-0.6305 |
|
| 139 |
N |
C |
-1.3608 |
|
| 140 |
F |
C |
0.0000 |
|
| 141 |
Y |
C |
0.0000 |
|
| 142 |
P |
C |
-1.6884 |
|
| 143 |
R |
C |
-2.7719 |
|
| 144 |
E |
C |
-3.0870 |
|
| 145 |
A |
C |
-2.1776 |
|
| 146 |
K |
C |
-2.3881 |
|
| 147 |
V |
C |
-1.1270 |
|
| 148 |
Q |
C |
-0.7393 |
|
| 149 |
W |
C |
0.0000 |
|
| 150 |
K |
C |
-0.6225 |
|
| 151 |
V |
C |
0.0000 |
|
| 152 |
D |
C |
-1.6892 |
|
| 153 |
N |
C |
-1.4895 |
|
| 154 |
A |
C |
-0.2174 |
|
| 155 |
L |
C |
0.7638 |
|
| 156 |
Q |
C |
-0.1110 |
|
| 157 |
S |
C |
-0.4355 |
|
| 158 |
G |
C |
-1.0009 |
|
| 159 |
N |
C |
-0.9451 |
|
| 160 |
S |
C |
-1.4955 |
|
| 161 |
Q |
C |
-2.3193 |
|
| 162 |
E |
C |
-2.3156 |
|
| 163 |
S |
C |
-1.0781 |
|
| 164 |
V |
C |
-0.6099 |
|
| 165 |
T |
C |
-1.2457 |
|
| 166 |
E |
C |
-2.3654 |
|
| 167 |
Q |
C |
-2.1507 |
|
| 168 |
D |
C |
-2.4589 |
|
| 169 |
S |
C |
-2.1645 |
|
| 170 |
K |
C |
-2.3372 |
|
| 171 |
D |
C |
-1.8094 |
|
| 172 |
S |
C |
0.0000 |
|
| 173 |
T |
C |
0.0000 |
|
| 174 |
Y |
C |
0.0000 |
|
| 175 |
S |
C |
-1.0111 |
|
| 176 |
L |
C |
0.0000 |
|
| 177 |
S |
C |
-0.4559 |
|
| 178 |
S |
C |
0.0000 |
|
| 179 |
T |
C |
-0.6747 |
|
| 180 |
L |
C |
0.0000 |
|
| 181 |
T |
C |
-0.4841 |
|
| 182 |
L |
C |
-0.6963 |
|
| 183 |
S |
C |
-1.3714 |
|
| 184 |
K |
C |
-2.3424 |
|
| 185 |
A |
C |
-2.0080 |
|
| 186 |
D |
C |
-2.6061 |
|
| 187 |
Y |
C |
0.0000 |
|
| 188 |
E |
C |
-3.8419 |
|
| 189 |
K |
C |
-3.7537 |
|
| 190 |
H |
C |
-3.2161 |
|
| 191 |
K |
C |
-3.4298 |
|
| 192 |
V |
C |
-1.5587 |
|
| 193 |
Y |
C |
0.0000 |
|
| 194 |
A |
C |
0.0000 |
|
| 195 |
C |
C |
0.0000 |
|
| 196 |
E |
C |
-0.9917 |
|
| 197 |
V |
C |
0.0000 |
|
| 198 |
T |
C |
-1.1641 |
|
| 199 |
H |
C |
0.0000 |
|
| 200 |
Q |
C |
-1.6897 |
|
| 201 |
G |
C |
-0.4071 |
|
| 202 |
L |
C |
-0.2058 |
|
| 203 |
S |
C |
-0.4360 |
|
| 204 |
S |
C |
-0.4122 |
|
| 205 |
P |
C |
-0.3548 |
|
| 206 |
V |
C |
-0.0956 |
|
| 207 |
T |
C |
-0.5598 |
|
| 208 |
K |
C |
-0.6560 |
|
| 209 |
S |
C |
-0.4529 |
|
| 210 |
F |
C |
-0.8359 |
|
| 211 |
N |
C |
-1.9979 |
|
| 212 |
R |
C |
-2.8533 |
|
| 213 |
G |
C |
-2.2756 |
|
| 214 |
E |
C |
-2.5629 |
|