Project name: 1cz8:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGYDFTHYGMNWVRQAPGKGLEWVGWINTYTGEPTYAADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYPYYYGTSHWYFDVWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2812
• Maximal score value: 2.5434
• Average score: -0.4873
• Total score value: -106.2247

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1166
2	V	H	-1.3564
3	Q	H	-1.2294
4	L	H	0.0000
5	V	H	0.9695
6	E	H	0.0000
7	S	H	-0.3635
8	G	H	-0.8510
9	G	H	-0.6428
10	G	H	-0.3006
11	L	H	-0.1541
12	V	H	0.0000
13	Q	H	-1.6723
14	P	H	-1.7229
15	G	H	-1.4557
16	G	H	-1.1834
17	S	H	-1.3183
18	L	H	-1.1810
19	R	H	-2.0198
20	L	H	0.0000
21	S	H	-0.2343
22	C	H	0.0000
23	A	H	-0.0115
24	A	H	0.0000
25	S	H	-1.2015
26	G	H	-1.5796
27	Y	H	-1.2781
28	D	H	-1.6663
29	F	H	0.0000
30	T	H	-0.4081
31	H	H	-0.7973
32	Y	H	-0.0332
33	G	H	0.0112
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.2276
39	Q	H	-0.6409
40	A	H	-1.1881
41	P	H	-1.1140
42	G	H	-1.4158
43	K	H	-2.1267
44	G	H	-1.0216
45	L	H	0.4252
46	E	H	-0.4152
47	W	H	0.3274
48	V	H	0.0000
49	G	H	0.0000
50	W	H	-0.0589
51	I	H	0.0000
52	N	H	-0.6161
53	T	H	0.0000
54	Y	H	0.7125
55	T	H	-0.1324
56	G	H	-0.8321
57	E	H	-1.8299
58	P	H	-1.2343
59	T	H	-0.6957
60	Y	H	-0.8314
61	A	H	-0.7438
62	A	H	-1.5280
63	D	H	-2.6124
64	F	H	0.0000
65	K	H	-3.1278
66	R	H	-3.2812
67	R	H	-2.2462
68	F	H	0.0000
69	T	H	-1.1186
70	F	H	0.0000
71	S	H	-0.2920
72	L	H	-0.2387
73	D	H	-0.8729
74	T	H	-0.8551
75	S	H	-1.1659
76	K	H	-1.9435
77	S	H	-1.2704
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.2897
81	L	H	0.0000
82	Q	H	-1.0944
83	M	H	0.0000
84	N	H	-1.6340
85	S	H	-1.4410
86	L	H	0.0000
87	R	H	-2.2890
88	A	H	-1.7100
89	E	H	-2.2027
90	D	H	0.0000
91	T	H	-0.8144
92	A	H	0.0000
93	V	H	0.2772
94	Y	H	0.0000
95	Y	H	0.3567
96	C	H	0.0000
97	A	H	0.0000
98	K	H	0.0000
99	Y	H	0.0000
100	P	H	0.9560
101	Y	H	1.7275
102	Y	H	2.3271
103	Y	H	1.8229
104	G	H	0.5713
105	T	H	0.2777
106	S	H	0.3977
107	H	H	0.3554
108	W	H	1.1153
109	Y	H	0.9650
110	F	H	0.4316
111	D	H	-0.6237
112	V	H	-0.3167
113	W	H	0.0511
114	G	H	-0.0544
115	Q	H	-0.7949
116	G	H	-0.1916
117	T	H	0.0000
118	L	H	0.1292
119	V	H	0.0000
120	T	H	-0.5176
121	V	H	0.0000
122	S	H	-0.8296
123	S	H	-0.7588
124	A	H	-0.4719
125	S	H	-0.5825
126	T	H	-0.7459
127	K	H	-1.2519
128	G	H	-1.5018
129	P	H	-0.6108
130	S	H	-0.0279
131	V	H	0.0000
132	F	H	1.4082
133	P	H	0.1649
134	L	H	0.4736
135	A	H	-0.8037
136	P	H	0.0000
137	S	H	-0.6285
144	G	H	-0.6404
145	T	H	-0.4891
146	A	H	-0.2879
147	A	H	0.0677
148	L	H	0.0000
149	G	H	0.0000
150	C	H	0.0000
151	L	H	0.8726
152	V	H	0.0000
153	K	H	-0.2161
154	D	H	-0.6470
155	Y	H	0.0000
156	F	H	0.0000
157	P	H	0.0000
158	E	H	-0.3782
159	P	H	-0.6783
160	V	H	-0.7016
161	T	H	-0.6595
162	V	H	-0.3734
163	S	H	-0.4489
164	W	H	0.0000
165	N	H	-0.8129
166	S	H	-0.6828
167	G	H	-0.5219
168	A	H	-0.2323
169	L	H	-0.0018
170	T	H	-0.2977
171	S	H	-0.3641
172	G	H	-0.4690
173	V	H	-0.0275
174	H	H	-0.5053
175	T	H	0.1850
176	F	H	0.9068
177	P	H	0.6942
178	A	H	1.2902
179	V	H	2.5434
180	L	H	2.2146
181	Q	H	0.7962
182	S	H	0.1697
183	S	H	-0.1539
184	G	H	0.3075
185	L	H	0.3771
186	Y	H	0.9229
187	S	H	0.0000
188	L	H	0.0000
189	S	H	0.6850
190	S	H	0.0000
191	V	H	0.3942
192	V	H	0.0000
193	T	H	-0.2795
194	V	H	0.0000
195	P	H	-0.5872
196	S	H	-0.5363
197	S	H	-0.5970
198	S	H	-0.5904
199	L	H	-0.8495
200	G	H	-0.9847
201	T	H	-0.8825
202	Q	H	-1.2002
203	T	H	-1.1297
204	Y	H	0.0000
205	I	H	-1.5153
206	C	H	0.0000
207	N	H	-1.6003
208	V	H	0.0000
209	N	H	-2.0843
210	H	H	0.0000
211	K	H	-2.7935
212	P	H	-1.6051
213	S	H	-1.8394
214	N	H	-2.5957
215	T	H	-2.1015
216	K	H	-2.7730
217	V	H	-1.8022
218	D	H	-2.6797
219	K	H	-2.1975
220	K	H	-2.5230
221	V	H	0.0000
222	E	H	-2.8546
223	P	H	-1.8605
224	K	H	-2.2115