| Chain sequence(s) |
H: EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYVMSWVRQAPGKGLEWVATISSGGSYTYYPDSVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCARRGDSMITTDYWGQGTLVTVS L: DIQMTQSPSSLSASVGDRVTITCKASQDVGTAVAWYQQKPGKAPKLLIYWASTRHTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSSYRTFGQGTKVEIK |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | D | L | -2.1409 | |
| 2 | I | L | 0.0000 | |
| 3 | Q | L | -2.3710 | |
| 4 | M | L | 0.0000 | |
| 5 | T | L | -1.3407 | |
| 6 | Q | L | 0.0000 | |
| 7 | S | L | -0.8234 | |
| 8 | P | L | -0.6238 | |
| 9 | S | L | -0.8750 | |
| 10 | S | L | -1.0585 | |
| 11 | L | L | -0.6296 | |
| 12 | S | L | -0.7298 | |
| 13 | A | L | 0.0000 | |
| 14 | S | L | -0.1522 | |
| 15 | V | L | 0.6149 | |
| 16 | G | L | -0.6533 | |
| 17 | D | L | -1.4935 | |
| 18 | R | L | -2.2325 | |
| 19 | V | L | 0.0000 | |
| 20 | T | L | -0.6132 | |
| 21 | I | L | 0.0000 | |
| 22 | T | L | -0.8134 | |
| 23 | C | L | 0.0000 | |
| 24 | K | L | -2.8209 | |
| 25 | A | L | 0.0000 | |
| 26 | S | L | -2.3384 | |
| 27 | Q | L | -3.0837 | |
| 28 | D | L | -2.9886 | |
| 29 | V | L | 0.0000 | |
| 30 | G | L | -1.2461 | |
| 31 | T | L | -0.6161 | |
| 32 | A | L | 0.0000 | |
| 33 | V | L | 0.0000 | |
| 34 | A | L | 0.0000 | |
| 35 | W | L | 0.0000 | |
| 36 | Y | L | 0.0000 | |
| 37 | Q | L | 0.0000 | |
| 38 | Q | L | 0.0000 | |
| 39 | K | L | -1.7102 | |
| 40 | P | L | -1.2881 | |
| 41 | G | L | -1.6908 | |
| 42 | K | L | -2.6237 | |
| 43 | A | L | -1.6891 | |
| 44 | P | L | 0.0000 | |
| 45 | K | L | -1.2606 | |
| 46 | L | L | 0.0000 | |
| 47 | L | L | 0.0000 | |
| 48 | I | L | 0.0000 | |
| 49 | Y | L | 0.0650 | |
| 50 | W | L | 0.3198 | |
| 51 | A | L | 0.0000 | |
| 52 | S | L | -0.5923 | |
| 53 | T | L | -0.7131 | |
| 54 | R | L | -1.5964 | |
| 55 | H | L | -1.1011 | |
| 56 | T | L | -0.6673 | |
| 57 | G | L | -0.7226 | |
| 58 | V | L | -0.7404 | |
| 59 | P | L | -0.5997 | |
| 60 | S | L | -0.7516 | |
| 61 | R | L | -0.7811 | |
| 62 | F | L | 0.0000 | |
| 63 | S | L | -0.6612 | |
| 64 | G | L | -0.5049 | |
| 65 | S | L | -0.6121 | |
| 66 | G | L | -1.0542 | |
| 67 | S | L | -1.2806 | |
| 68 | G | L | -1.8712 | |
| 69 | T | L | -2.3515 | |
| 70 | D | L | -2.5086 | |
| 71 | F | L | 0.0000 | |
| 72 | T | L | -0.7586 | |
| 73 | L | L | 0.0000 | |
| 74 | T | L | -0.6122 | |
| 75 | I | L | 0.0000 | |
| 76 | S | L | -1.2349 | |
| 77 | S | L | -1.0698 | |
| 78 | L | L | 0.0000 | |
| 79 | Q | L | -0.8244 | |
| 80 | P | L | -0.6363 | |
| 81 | E | L | -1.8539 | |
| 82 | D | L | 0.0000 | |
| 83 | F | L | -0.4945 | |
| 84 | A | L | 0.0000 | |
| 85 | T | L | -1.0501 | |
| 86 | Y | L | 0.0000 | |
| 87 | Y | L | 0.0000 | |
| 88 | C | L | 0.0000 | |
| 89 | Q | L | 0.0000 | |
| 90 | Q | L | 0.0000 | |
| 91 | Y | L | 0.0000 | |
| 92 | S | L | -0.5145 | |
| 93 | S | L | -0.4165 | |
| 94 | Y | L | 0.5676 | |
| 95 | R | L | -0.5869 | |
| 97 | T | L | -0.9457 | |
| 98 | F | L | 0.0000 | |
| 99 | G | L | 0.0000 | |
| 100 | Q | L | -1.7337 | |
| 101 | G | L | 0.0000 | |
| 102 | T | L | 0.0000 | |
| 103 | K | L | -1.7375 | |
| 104 | V | L | 0.0000 | |
| 105 | E | L | -0.9890 | |
| 106 | I | L | 0.6978 | |
| 107 | K | L | -0.8364 | |
| 1 | E | H | -2.0344 | |
| 2 | V | H | -1.0301 | |
| 3 | Q | H | -1.1523 | |
| 4 | L | H | 0.0000 | |
| 5 | V | H | 1.1764 | |
| 6 | E | H | 0.0000 | |
| 7 | S | H | -0.0641 | |
| 8 | G | H | -0.6591 | |
| 9 | G | H | 0.0775 | |
| 10 | G | H | 0.8014 | |
| 11 | L | H | 1.3658 | |
| 12 | V | H | -0.0218 | |
| 13 | Q | H | -1.2820 | |
| 14 | P | H | -1.5124 | |
| 15 | G | H | -1.4132 | |
| 16 | G | H | -0.9800 | |
| 17 | S | H | -1.2597 | |
| 18 | L | H | -0.9314 | |
| 19 | R | H | -2.0233 | |
| 20 | L | H | 0.0000 | |
| 21 | S | H | -0.1979 | |
| 22 | C | H | 0.0000 | |
| 23 | A | H | 0.0227 | |
| 24 | A | H | 0.0000 | |
| 25 | S | H | -0.6957 | |
| 26 | G | H | -1.0758 | |
| 27 | F | H | -0.4130 | |
| 28 | T | H | -0.1554 | |
| 29 | F | H | 0.0000 | |
| 30 | S | H | -0.7128 | |
| 31 | S | H | -0.4275 | |
| 32 | Y | H | -0.1686 | |
| 33 | V | H | -0.1019 | |
| 34 | M | H | 0.0000 | |
| 35 | S | H | 0.0000 | |
| 36 | W | H | 0.0000 | |
| 37 | V | H | 0.0000 | |
| 38 | R | H | 0.0000 | |
| 39 | Q | H | -0.8113 | |
| 40 | A | H | -1.1683 | |
| 41 | P | H | -0.8874 | |
| 42 | G | H | -1.5104 | |
| 43 | K | H | -2.4140 | |
| 44 | G | H | -1.7326 | |
| 45 | L | H | -1.1296 | |
| 46 | E | H | -1.6442 | |
| 47 | W | H | -0.4455 | |
| 48 | V | H | 0.0000 | |
| 49 | A | H | 0.0000 | |
| 50 | T | H | 0.0000 | |
| 51 | I | H | 0.0000 | |
| 52 | S | H | 0.0424 | |
| 52A | S | H | -0.3730 | |
| 53 | G | H | -0.5468 | |
| 54 | G | H | -0.3123 | |
| 55 | S | H | 0.1702 | |
| 56 | Y | H | 1.1485 | |
| 57 | T | H | 0.7621 | |
| 58 | Y | H | 0.4620 | |
| 59 | Y | H | -0.7584 | |
| 60 | P | H | -1.4708 | |
| 61 | D | H | -2.4910 | |
| 62 | S | H | -1.8265 | |
| 63 | V | H | 0.0000 | |
| 64 | K | H | -2.5614 | |
| 65 | G | H | -1.8530 | |
| 66 | R | H | -1.5928 | |
| 67 | F | H | 0.0000 | |
| 68 | T | H | -0.7948 | |
| 69 | I | H | 0.0000 | |
| 70 | S | H | -0.1983 | |
| 71 | R | H | -0.9322 | |
| 72 | D | H | -1.4575 | |
| 73 | N | H | -1.6514 | |
| 74 | A | H | -1.3182 | |
| 75 | K | H | -2.2158 | |
| 76 | N | H | -1.6125 | |
| 77 | T | H | -0.8102 | |
| 78 | L | H | 0.0000 | |
| 79 | Y | H | -0.2386 | |
| 80 | L | H | 0.0000 | |
| 81 | Q | H | -1.1030 | |
| 82 | M | H | 0.0000 | |
| 82A | N | H | -1.5331 | |
| 82B | S | H | -1.3122 | |
| 82C | L | H | 0.0000 | |
| 83 | R | H | -2.2841 | |
| 84 | A | H | -1.6731 | |
| 85 | E | H | -2.2304 | |
| 86 | D | H | 0.0000 | |
| 87 | T | H | -0.4277 | |
| 88 | A | H | 0.0000 | |
| 89 | V | H | 0.5696 | |
| 90 | Y | H | 0.0000 | |
| 91 | Y | H | 0.0000 | |
| 92 | C | H | 0.0000 | |
| 93 | A | H | 0.0000 | |
| 94 | R | H | -0.0932 | |
| 95 | R | H | 0.0000 | |
| 96 | G | H | -0.5734 | |
| 97 | D | H | -1.5812 | |
| 98 | S | H | -0.7428 | |
| 99 | M | H | 0.1580 | |
| 100 | I | H | 0.0000 | |
| 100A | T | H | 0.0000 | |
| 100B | T | H | 0.0000 | |
| 101 | D | H | 0.0000 | |
| 102 | Y | H | 0.1420 | |
| 103 | W | H | 0.0000 | |
| 104 | G | H | 0.0000 | |
| 105 | Q | H | -1.2400 | |
| 106 | G | H | 0.0000 | |
| 107 | T | H | 0.5006 | |
| 108 | L | H | 1.2829 | |
| 109 | V | H | 0.0000 | |
| 110 | T | H | 0.3341 | |
| 111 | V | H | 0.0000 | |
| 112 | S | H | -0.5341 |