Project name: 3vfg:L
Status: done
submitted: 2019-03-20 20:13:46, status changed: 2019-03-20 20:24:25
Settings
|
Chain sequence(s)
|
L: SIVMTQTPKFLLVSAGDRVTITCKASQSVSNDVTWYQQKAGQSPKLLIYSASNRYSGVPDRFTGSGYGTAFTFTISTVQAEDLAVYFCQQDYSSFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6509
-
Maximal score value
-
1.7404
-
Average score
-
-0.7531
-
Total score value
-
-158.9059
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
S |
L |
0.3386 |
|
| 2 |
I |
L |
0.7424 |
|
| 3 |
V |
L |
1.4754 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
0.0376 |
|
| 6 |
Q |
L |
-0.5356 |
|
| 7 |
T |
L |
-0.6208 |
|
| 8 |
P |
L |
-0.5486 |
|
| 9 |
K |
L |
-1.1561 |
|
| 10 |
F |
L |
0.9428 |
|
| 11 |
L |
L |
0.8934 |
|
| 12 |
L |
L |
1.0766 |
|
| 13 |
V |
L |
0.0000 |
|
| 14 |
S |
L |
-1.1544 |
|
| 15 |
A |
L |
-1.3194 |
|
| 16 |
G |
L |
-1.3909 |
|
| 17 |
D |
L |
-1.9497 |
|
| 18 |
R |
L |
-2.5394 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.4588 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.4164 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
K |
L |
-1.2805 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.3925 |
|
| 27 |
Q |
L |
-1.1592 |
|
| 28 |
S |
L |
-0.9411 |
|
| 29 |
V |
L |
-0.8900 |
|
| 30 |
S |
L |
-0.5511 |
|
| 31 |
N |
L |
-0.9223 |
|
| 32 |
D |
L |
-2.1386 |
|
| 33 |
V |
L |
0.0000 |
|
| 34 |
T |
L |
-0.1477 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0698 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.3405 |
|
| 39 |
K |
L |
-1.5284 |
|
| 40 |
A |
L |
-1.1558 |
|
| 41 |
G |
L |
-1.4378 |
|
| 42 |
Q |
L |
-1.9761 |
|
| 43 |
S |
L |
-1.4228 |
|
| 44 |
P |
L |
-1.2685 |
|
| 45 |
K |
L |
-1.3158 |
|
| 46 |
L |
L |
0.0280 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.2460 |
|
| 50 |
S |
L |
-0.6347 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.5840 |
|
| 53 |
N |
L |
-0.5046 |
|
| 54 |
R |
L |
-0.6164 |
|
| 55 |
Y |
L |
0.7134 |
|
| 56 |
S |
L |
0.0295 |
|
| 57 |
G |
L |
-0.4826 |
|
| 58 |
V |
L |
-0.5837 |
|
| 59 |
P |
L |
-1.1253 |
|
| 60 |
D |
L |
-2.1955 |
|
| 61 |
R |
L |
-1.6015 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
T |
L |
-0.8893 |
|
| 64 |
G |
L |
0.0000 |
|
| 65 |
S |
L |
-0.2505 |
|
| 66 |
G |
L |
-0.1179 |
|
| 67 |
Y |
L |
0.6631 |
|
| 68 |
G |
L |
-0.2711 |
|
| 69 |
T |
L |
-0.7452 |
|
| 70 |
A |
L |
-0.3365 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.2141 |
|
| 73 |
F |
L |
0.0000 |
|
| 74 |
T |
L |
-0.5504 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.5785 |
|
| 77 |
T |
L |
-1.6158 |
|
| 78 |
V |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.6433 |
|
| 80 |
A |
L |
-2.3314 |
|
| 81 |
E |
L |
-2.4543 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
L |
L |
-1.2466 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
V |
L |
-0.4038 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
F |
L |
0.1625 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.3924 |
|
| 90 |
Q |
L |
-0.5827 |
|
| 91 |
D |
L |
-1.1132 |
|
| 92 |
Y |
L |
0.5458 |
|
| 96 |
S |
L |
0.4832 |
|
| 97 |
S |
L |
0.0000 |
|
| 98 |
F |
L |
1.7404 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
G |
L |
-0.3050 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-0.7903 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
-0.4867 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.5358 |
|
| 108 |
R |
L |
-1.8680 |
|
| 109 |
A |
L |
-1.3833 |
|
| 110 |
D |
L |
-2.4444 |
|
| 111 |
A |
L |
-1.4314 |
|
| 112 |
A |
L |
-0.7616 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
T |
L |
-0.2401 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
S |
L |
0.4567 |
|
| 117 |
I |
L |
1.0236 |
|
| 118 |
F |
L |
1.6968 |
|
| 119 |
P |
L |
0.7181 |
|
| 120 |
P |
L |
-0.1054 |
|
| 121 |
S |
L |
-0.6503 |
|
| 122 |
S |
L |
-1.2492 |
|
| 123 |
E |
L |
-2.1597 |
|
| 124 |
Q |
L |
-1.4720 |
|
| 125 |
L |
L |
-1.3682 |
|
| 126 |
T |
L |
-1.0033 |
|
| 127 |
S |
L |
-0.9376 |
|
| 128 |
G |
L |
-1.1900 |
|
| 129 |
G |
L |
-1.1484 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.1160 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
1.1607 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
F |
L |
0.4815 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6742 |
|
| 138 |
N |
L |
-1.4450 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
-2.1542 |
|
| 141 |
P |
L |
-2.2006 |
|
| 142 |
K |
L |
-2.6153 |
|
| 143 |
D |
L |
-2.7668 |
|
| 144 |
I |
L |
-1.8394 |
|
| 145 |
N |
L |
-1.9999 |
|
| 146 |
V |
L |
-0.8867 |
|
| 147 |
K |
L |
-1.7289 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-2.4925 |
|
| 150 |
I |
L |
0.0000 |
|
| 151 |
D |
L |
-2.9355 |
|
| 152 |
G |
L |
-2.1647 |
|
| 153 |
S |
L |
-2.2609 |
|
| 154 |
E |
L |
-3.2638 |
|
| 155 |
R |
L |
-2.7483 |
|
| 156 |
Q |
L |
-2.3949 |
|
| 157 |
N |
L |
-1.9227 |
|
| 158 |
G |
L |
-0.6166 |
|
| 159 |
V |
L |
0.0111 |
|
| 160 |
L |
L |
0.8733 |
|
| 161 |
N |
L |
-0.2305 |
|
| 162 |
S |
L |
-0.3106 |
|
| 163 |
W |
L |
-0.7283 |
|
| 164 |
T |
L |
-1.1986 |
|
| 165 |
D |
L |
-2.2090 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.8213 |
|
| 168 |
S |
L |
-2.7572 |
|
| 169 |
K |
L |
-3.3496 |
|
| 170 |
D |
L |
-3.3096 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
0.0000 |
|
| 175 |
M |
L |
0.0000 |
|
| 176 |
S |
L |
0.1755 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
0.7367 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.0523 |
|
| 181 |
L |
L |
0.0000 |
|
| 182 |
T |
L |
-1.4801 |
|
| 183 |
K |
L |
-2.3923 |
|
| 184 |
D |
L |
-3.3395 |
|
| 185 |
E |
L |
-2.7991 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.6172 |
|
| 188 |
R |
L |
-3.6509 |
|
| 189 |
H |
L |
-2.8483 |
|
| 190 |
N |
L |
-2.5049 |
|
| 191 |
S |
L |
-1.8720 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
T |
L |
-1.1304 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.3772 |
|
| 196 |
A |
L |
0.0000 |
|
| 197 |
T |
L |
-0.9739 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
K |
L |
-2.5917 |
|
| 200 |
T |
L |
-1.3390 |
|
| 201 |
S |
L |
-0.7677 |
|
| 202 |
T |
L |
-0.5872 |
|
| 203 |
S |
L |
-0.3275 |
|
| 204 |
P |
L |
-0.2729 |
|
| 205 |
I |
L |
0.7137 |
|
| 206 |
V |
L |
0.7095 |
|
| 207 |
K |
L |
-0.0546 |
|
| 208 |
S |
L |
-0.3459 |
|
| 209 |
F |
L |
0.0000 |
|
| 210 |
N |
L |
-1.8724 |
|
| 211 |
R |
L |
-2.1881 |
|
| 212 |
N |
L |
-2.5447 |
|
| 213 |
E |
L |
-2.3973 |
|
| 214 |
C |
L |
-0.7053 |
|