Project name: 4lly:B
Status: done
submitted: 2019-03-21 14:59:09, status changed: 2019-03-21 15:07:44
Settings
|
Chain sequence(s)
|
B: RIQMTQSPSSLSASVGDRVTITCKASQDVSIGVAWYQDKPGKAPKLLIYSASYRYTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYYIYPYTFGQGTKVEIKGQPKAAPSVTLFPPSSEELQANKATLVCYISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAAWSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.2054
-
Maximal score value
-
2.2692
-
Average score
-
-0.7349
-
Total score value
-
-153.5921
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
R |
B |
-2.0223 |
|
| 2 |
I |
B |
0.0000 |
|
| 3 |
Q |
B |
-1.7907 |
|
| 4 |
M |
B |
0.0000 |
|
| 5 |
T |
B |
-1.2207 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.8263 |
|
| 8 |
P |
B |
-0.6826 |
|
| 9 |
S |
B |
-0.9532 |
|
| 10 |
S |
B |
-1.1299 |
|
| 11 |
L |
B |
-0.8796 |
|
| 12 |
S |
B |
-1.3052 |
|
| 13 |
A |
B |
0.0000 |
|
| 14 |
S |
B |
-1.2952 |
|
| 15 |
V |
B |
-0.5996 |
|
| 16 |
G |
B |
-1.1187 |
|
| 17 |
D |
B |
-1.9152 |
|
| 18 |
R |
B |
-2.4225 |
|
| 19 |
V |
B |
0.0000 |
|
| 20 |
T |
B |
-0.6209 |
|
| 21 |
I |
B |
0.0000 |
|
| 22 |
T |
B |
-0.7923 |
|
| 23 |
C |
B |
0.0000 |
|
| 24 |
K |
B |
-2.7411 |
|
| 25 |
A |
B |
0.0000 |
|
| 26 |
S |
B |
-2.0236 |
|
| 27 |
Q |
B |
-2.1055 |
|
| 28 |
D |
B |
-2.3858 |
|
| 29 |
V |
B |
0.0000 |
|
| 30 |
S |
B |
-0.4420 |
|
| 31 |
I |
B |
0.6121 |
|
| 32 |
G |
B |
0.0000 |
|
| 33 |
V |
B |
0.0000 |
|
| 34 |
A |
B |
0.0000 |
|
| 35 |
W |
B |
0.0000 |
|
| 36 |
Y |
B |
0.0937 |
|
| 37 |
Q |
B |
0.0000 |
|
| 38 |
D |
B |
-1.4948 |
|
| 39 |
K |
B |
-1.7877 |
|
| 40 |
P |
B |
-1.3209 |
|
| 41 |
G |
B |
-1.5816 |
|
| 42 |
K |
B |
-2.4337 |
|
| 43 |
A |
B |
-1.4678 |
|
| 44 |
P |
B |
-1.4028 |
|
| 45 |
K |
B |
-1.4271 |
|
| 46 |
L |
B |
-0.0627 |
|
| 47 |
L |
B |
0.0000 |
|
| 48 |
I |
B |
0.0000 |
|
| 49 |
Y |
B |
1.1481 |
|
| 50 |
S |
B |
0.6733 |
|
| 51 |
A |
B |
0.0000 |
|
| 52 |
S |
B |
0.3661 |
|
| 53 |
Y |
B |
1.1404 |
|
| 54 |
R |
B |
0.0110 |
|
| 55 |
Y |
B |
0.6127 |
|
| 56 |
T |
B |
0.0827 |
|
| 57 |
G |
B |
-0.4861 |
|
| 58 |
V |
B |
0.0000 |
|
| 59 |
P |
B |
-0.4977 |
|
| 60 |
S |
B |
-0.7155 |
|
| 61 |
R |
B |
-0.8581 |
|
| 62 |
F |
B |
0.0000 |
|
| 63 |
S |
B |
-0.4389 |
|
| 64 |
G |
B |
-0.2003 |
|
| 65 |
S |
B |
-0.4256 |
|
| 66 |
G |
B |
-0.9486 |
|
| 67 |
S |
B |
-0.8432 |
|
| 68 |
G |
B |
-1.5198 |
|
| 69 |
T |
B |
-2.0804 |
|
| 70 |
D |
B |
-2.5375 |
|
| 71 |
F |
B |
0.0000 |
|
| 72 |
T |
B |
-0.8068 |
|
| 73 |
L |
B |
0.0000 |
|
| 74 |
T |
B |
-0.6402 |
|
| 75 |
I |
B |
0.0000 |
|
| 76 |
S |
B |
-1.4934 |
|
| 77 |
S |
B |
-1.3787 |
|
| 78 |
L |
B |
0.0000 |
|
| 79 |
Q |
B |
-1.0367 |
|
| 80 |
P |
B |
-1.4586 |
|
| 81 |
E |
B |
-1.5564 |
|
| 82 |
D |
B |
0.0000 |
|
| 83 |
F |
B |
-1.0411 |
|
| 84 |
A |
B |
0.0000 |
|
| 85 |
T |
B |
0.0000 |
|
| 86 |
Y |
B |
0.0000 |
|
| 87 |
Y |
B |
-0.0070 |
|
| 88 |
C |
B |
0.0000 |
|
| 89 |
Q |
B |
0.0000 |
|
| 90 |
Q |
B |
0.0000 |
|
| 91 |
Y |
B |
1.9318 |
|
| 92 |
Y |
B |
2.2692 |
|
| 93 |
I |
B |
1.8544 |
|
| 94 |
Y |
B |
1.8436 |
|
| 95 |
P |
B |
1.0563 |
|
| 96 |
Y |
B |
1.8866 |
|
| 97 |
T |
B |
0.8460 |
|
| 98 |
F |
B |
1.1266 |
|
| 99 |
G |
B |
0.0000 |
|
| 100 |
Q |
B |
-1.0535 |
|
| 101 |
G |
B |
0.0000 |
|
| 102 |
T |
B |
0.0000 |
|
| 103 |
K |
B |
-2.1353 |
|
| 104 |
V |
B |
0.0000 |
|
| 105 |
E |
B |
-1.6127 |
|
| 106 |
I |
B |
0.0000 |
|
| 107 |
K |
B |
-2.2721 |
|
| 108 |
G |
B |
-1.4961 |
|
| 109 |
Q |
B |
0.0000 |
|
| 110 |
P |
B |
-1.6060 |
|
| 111 |
K |
B |
-2.5559 |
|
| 112 |
A |
B |
-1.5126 |
|
| 113 |
A |
B |
-0.8103 |
|
| 114 |
P |
B |
0.0000 |
|
| 115 |
S |
B |
-0.6847 |
|
| 116 |
V |
B |
0.0000 |
|
| 117 |
T |
B |
-0.0541 |
|
| 118 |
L |
B |
0.0000 |
|
| 119 |
F |
B |
1.1810 |
|
| 120 |
P |
B |
0.4584 |
|
| 121 |
P |
B |
0.0000 |
|
| 122 |
S |
B |
-1.0982 |
|
| 123 |
S |
B |
-1.8150 |
|
| 124 |
E |
B |
-2.8537 |
|
| 125 |
E |
B |
-2.4897 |
|
| 126 |
L |
B |
-2.4440 |
|
| 127 |
Q |
B |
-2.6502 |
|
| 128 |
A |
B |
-2.2307 |
|
| 129 |
N |
B |
-2.9690 |
|
| 130 |
K |
B |
-3.0875 |
|
| 131 |
A |
B |
0.0000 |
|
| 132 |
T |
B |
-0.1864 |
|
| 133 |
L |
B |
0.0000 |
|
| 134 |
V |
B |
0.9441 |
|
| 135 |
C |
B |
0.0000 |
|
| 136 |
Y |
B |
0.7396 |
|
| 137 |
I |
B |
0.0000 |
|
| 138 |
S |
B |
-0.8243 |
|
| 139 |
D |
B |
-1.9028 |
|
| 140 |
F |
B |
0.0000 |
|
| 141 |
Y |
B |
0.0000 |
|
| 142 |
P |
B |
-1.5533 |
|
| 143 |
G |
B |
-1.0416 |
|
| 144 |
A |
B |
-0.2494 |
|
| 145 |
V |
B |
-0.1583 |
|
| 146 |
T |
B |
-0.1338 |
|
| 147 |
V |
B |
-0.0422 |
|
| 148 |
A |
B |
-0.5316 |
|
| 149 |
W |
B |
0.0000 |
|
| 150 |
K |
B |
-1.2293 |
|
| 151 |
A |
B |
-1.3380 |
|
| 152 |
D |
B |
-1.5855 |
|
| 153 |
S |
B |
-1.0145 |
|
| 154 |
S |
B |
-0.7229 |
|
| 155 |
P |
B |
-0.9393 |
|
| 156 |
V |
B |
-0.9367 |
|
| 157 |
K |
B |
-1.8538 |
|
| 158 |
A |
B |
-1.0440 |
|
| 159 |
G |
B |
-0.9708 |
|
| 160 |
V |
B |
-0.9836 |
|
| 161 |
E |
B |
-1.7483 |
|
| 162 |
T |
B |
-0.5824 |
|
| 163 |
T |
B |
-0.3423 |
|
| 164 |
T |
B |
-0.1129 |
|
| 165 |
P |
B |
-0.3897 |
|
| 166 |
S |
B |
-0.8312 |
|
| 167 |
K |
B |
-1.8344 |
|
| 168 |
Q |
B |
-2.2300 |
|
| 169 |
S |
B |
-2.2023 |
|
| 170 |
N |
B |
-2.4616 |
|
| 171 |
N |
B |
-2.6646 |
|
| 172 |
K |
B |
-2.4158 |
|
| 173 |
Y |
B |
0.0000 |
|
| 174 |
A |
B |
0.0000 |
|
| 175 |
A |
B |
0.0000 |
|
| 176 |
W |
B |
0.3604 |
|
| 177 |
S |
B |
0.0000 |
|
| 178 |
Y |
B |
0.1624 |
|
| 179 |
L |
B |
0.0000 |
|
| 180 |
S |
B |
-0.7027 |
|
| 181 |
L |
B |
-1.1507 |
|
| 182 |
T |
B |
-1.8607 |
|
| 183 |
P |
B |
-2.5893 |
|
| 184 |
E |
B |
-3.2054 |
|
| 185 |
Q |
B |
-2.3284 |
|
| 186 |
W |
B |
0.0000 |
|
| 187 |
K |
B |
-3.1329 |
|
| 188 |
S |
B |
-2.4133 |
|
| 189 |
H |
B |
-2.4500 |
|
| 190 |
R |
B |
-2.5648 |
|
| 191 |
S |
B |
0.0000 |
|
| 192 |
Y |
B |
0.0000 |
|
| 193 |
S |
B |
0.0000 |
|
| 194 |
C |
B |
0.0000 |
|
| 195 |
Q |
B |
-1.1366 |
|
| 196 |
V |
B |
0.0000 |
|
| 197 |
T |
B |
-0.6824 |
|
| 198 |
H |
B |
0.0000 |
|
| 199 |
E |
B |
-2.2693 |
|
| 200 |
G |
B |
-1.4518 |
|
| 201 |
S |
B |
-0.8538 |
|
| 202 |
T |
B |
-0.6795 |
|
| 203 |
V |
B |
-0.6760 |
|
| 204 |
E |
B |
-2.1836 |
|
| 205 |
K |
B |
-1.8540 |
|
| 206 |
T |
B |
-0.9834 |
|
| 207 |
V |
B |
-0.2510 |
|
| 208 |
A |
B |
-0.7609 |
|
| 209 |
P |
B |
-1.1006 |
|