Project name: 71dc42524ca6488

Chain sequence(s)	H: VQLQQSGPEMVKPGASVKMSCKASGYTFTNYVLHWVKQKPGQGLEWIGYINPYNDGTNYNAKFKDKATLTSDKSSSTAYMELSSLTSEDSAVYYCSKGGYYTLDYWGQGTSVTVSS; L: DVVMTQTPLSLPVSFGDQASISCRSSQSLVHSKGNTYLHWYLQKPGQSPKLLIYKISNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCSQSTHVPFTFGSGTKLEIK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.261
• Maximal score value: 1.4119
• Average score: -0.6272
• Total score value: -143.0069

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-1.0904
2	V	L	0.0000
3	V	L	0.7858
4	M	L	0.0000
5	T	L	-0.3227
6	Q	L	-0.3760
7	T	L	-0.0845
8	P	L	0.3758
9	L	L	1.1675
10	S	L	0.0205
11	L	L	-0.2509
12	P	L	-0.7662
13	V	L	0.0000
14	S	L	-0.8545
15	F	L	0.1620
16	G	L	-1.1238
17	D	L	-2.4839
18	Q	L	-2.7341
19	A	L	0.0000
20	S	L	-0.8461
21	I	L	0.0000
22	S	L	-0.7988
23	C	L	0.0000
24	R	L	-2.2596
25	S	L	0.0000
26	S	L	-0.8671
27	Q	L	-1.2271
28	S	L	-0.7012
29	L	L	0.0000
30	V	L	0.4623
30A	H	L	-0.5835
30B	S	L	-1.0518
30C	K	L	-2.0037
30D	G	L	-1.2500
30E	N	L	-0.8749
31	T	L	0.0000
32	Y	L	0.1837
33	L	L	0.0000
34	H	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	L	L	0.0000
38	Q	L	-1.0522
39	K	L	-1.4564
40	P	L	-0.9987
41	G	L	-1.4866
42	Q	L	-2.1683
43	S	L	-1.4361
44	P	L	0.0000
45	K	L	-1.4425
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.3884
50	K	L	-0.7208
51	I	L	-0.4813
52	S	L	-0.8125
53	N	L	-1.3687
54	R	L	-1.6127
55	F	L	-0.6168
56	S	L	-0.5433
57	G	L	-0.8154
58	V	L	-0.8972
59	P	L	-1.3534
60	D	L	-2.4299
61	R	L	-2.2059
62	F	L	0.0000
63	S	L	-1.3070
64	G	L	0.0000
65	S	L	-0.6534
66	G	L	-0.9050
67	S	L	-0.6723
68	G	L	-0.6651
69	T	L	-1.4123
70	D	L	-1.9924
71	F	L	0.0000
72	T	L	-0.8955
73	L	L	0.0000
74	K	L	-1.7667
75	I	L	0.0000
76	S	L	-2.6006
77	R	L	-2.9148
78	V	L	0.0000
79	E	L	-1.4300
80	A	L	-0.8165
81	E	L	-1.6633
82	D	L	0.0000
83	L	L	-0.5784
84	G	L	0.0000
85	V	L	-0.1288
86	Y	L	0.0000
87	F	L	0.0000
88	C	L	0.0000
89	S	L	0.0000
90	Q	L	0.0000
91	S	L	0.4629
92	T	L	0.2847
93	H	L	0.4069
94	V	L	1.2530
95	P	L	0.4666
96	F	L	0.5477
97	T	L	0.3280
98	F	L	0.2994
99	G	L	0.0000
100	S	L	-0.0816
101	G	L	0.0000
102	T	L	0.0000
103	K	L	-0.6504
104	L	L	0.0000
105	E	L	-1.3822
106	I	L	-0.7569
107	K	L	-1.4568
2	V	H	0.4941
3	Q	H	-1.2118
4	L	H	0.0000
5	Q	H	-2.1693
6	Q	H	0.0000
7	S	H	-1.1961
8	G	H	-1.1101
9	P	H	-0.6482
10	E	H	-0.9153
11	M	H	0.2590
12	V	H	-0.5443
13	K	H	-1.7999
14	P	H	-1.2001
15	G	H	-1.0899
16	A	H	-0.9003
17	S	H	-1.1684
18	V	H	0.0000
19	K	H	-2.0342
20	M	H	0.0000
21	S	H	-0.8866
22	C	H	0.0000
23	K	H	-1.6561
24	A	H	0.0000
25	S	H	-0.7397
26	G	H	-0.2392
27	Y	H	-0.1393
28	T	H	-0.3660
29	F	H	0.0000
30	T	H	-0.8303
31	N	H	-0.8202
32	Y	H	0.1289
33	V	H	-0.0882
34	L	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	K	H	-0.7612
39	Q	H	0.0000
40	K	H	-1.8220
41	P	H	-1.1755
42	G	H	-1.4097
43	Q	H	-1.9879
44	G	H	-1.2530
45	L	H	0.0000
46	E	H	-1.2084
47	W	H	0.0000
48	I	H	0.0000
49	G	H	0.0000
50	Y	H	-0.3683
51	I	H	0.0000
52	N	H	-1.0683
52A	P	H	0.0000
53	Y	H	-0.4848
54	N	H	-1.8097
55	D	H	-2.5103
56	G	H	-1.5890
57	T	H	-1.2885
58	N	H	-1.1933
59	Y	H	-0.8961
60	N	H	-1.1346
61	A	H	-1.6916
62	K	H	-2.4910
63	F	H	0.0000
64	K	H	-3.2610
65	D	H	-3.0594
66	K	H	-2.2135
67	A	H	0.0000
68	T	H	-1.1832
69	L	H	0.0000
70	T	H	-0.6811
71	S	H	-1.3693
72	D	H	-1.8535
73	K	H	-2.3509
74	S	H	-1.3503
75	S	H	-1.1866
76	S	H	-1.2893
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.5429
80	M	H	0.0000
81	E	H	-1.6711
82	L	H	0.0000
82A	S	H	-1.2704
82B	S	H	-1.0217
82C	L	H	0.0000
83	T	H	-1.2328
84	S	H	-1.4379
85	E	H	-2.0736
86	D	H	0.0000
87	S	H	-0.8258
88	A	H	0.0000
89	V	H	-0.1099
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	S	H	0.0000
94	K	H	0.0000
95	G	H	0.3014
96	G	H	0.4112
97	Y	H	1.4119
98	Y	H	0.9931
99	T	H	0.5310
100	L	H	0.0000
101	D	H	0.2303
102	Y	H	0.1851
103	W	H	-0.5780
104	G	H	0.0000
105	Q	H	-1.9161
106	G	H	-1.0931
107	T	H	0.0000
108	S	H	-0.4575
109	V	H	0.0000
110	T	H	-0.3793
111	V	H	0.0000
112	S	H	-0.5754
113	S	H	-0.7115